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Aprea Therapeutics, Inc. (APRE) 10-Year Financial Performance & Capital Metrics

APRE • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsSolid Tumor Oncology
AboutAprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel cancer therapeutics that target DNA damage response pathways. Its lead product candidate is ATRN-119, an oral ATR inhibitor that is in phase 1/2a clinical trial to treat patients with advanced solid tumors. The company's products pipeline also includes ATRN-Backup, an ATR inhibitor; ATRN-W1051 to treat anti-tumor activity; and ATRN-DDRi. Aprea Therapeutics, Inc. is based in Boston, Massachusetts.Show more
  • Revenue $2M +157.6%
  • EBITDA -$14M +7.5%
  • Net Income -$13M +9.3%
  • EPS (Diluted) -2.35 +40.5%
  • Gross Margin -523.16% -629.6%
  • EBITDA Margin -951.52% +64.1%
  • Operating Margin -953% +64.1%
  • Net Margin -862.43% +64.8%
  • ROE -68.98% -6.0%
  • ROIC -
  • Debt/Equity -
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Trading at only 0.3x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 7 (bottom 7%)
  • ✗Shares diluted 52.3% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-62.75%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM3.47%

EPS CAGR

10Y-
5Y-
3Y-
TTM23.49%

ROCE

10Y Avg-87.46%
5Y Avg-109.99%
3Y Avg-146.23%
Latest-73.65%

Peer Comparison

Solid Tumor Oncology
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Sector-Specific
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TLXTelix Pharmaceuticals Limited2.49B7.4353.0755.85%3.98%15.63%0.36%1.02
EXELExelixis, Inc.12.18B45.4425.8218.49%29.63%31.37%5.2%0.09
BBOTBridgeBio Oncology Therapeutics Inc.919.87M11.5025-25.73%
INBXInhibrx Biosciences, Inc.1.04B71.800.62-88.89%-110.78%-421.09%0.06
NUVBNuvation Bio Inc.2.1B6.14-2.91-8.13%-66.74%0.02
RLAYRelay Therapeutics, Inc.1.32B7.63-3.23-60.83%-26.71%-48.97%0.06
ORICORIC Pharmaceuticals, Inc.1.12B11.52-6.30-33.24%0.01
ZLABZai Lab Limited2.09B18.82-7.2449.59%-46.83%-27.21%0.18

Profit & Loss

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+000000583.23K1.5M
Revenue Growth %-------1.58%
Cost of Goods Sold+7.93K8.32K170.25K229.61K271.68K16.4M7.05K9.36M
COGS % of Revenue------0.01%6.23%
Gross Profit+-7.93K-8.32K-170.25K-229.61K-271.68K-16.4M576.18K-7.86M
Gross Margin %------0.99%-5.23%
Gross Profit Growth %--0.05%-19.47%-0.35%-0.18%-59.37%1.04%-14.64%
Operating Expenses+15.85M16.49M29.37M52.81M37.17M96.99M16.05M6.46M
OpEx % of Revenue------27.52%4.3%
Selling, General & Admin2.46M2.29M8.42M14.93M13.55M20.97M8.42M6.46M
SG&A % of Revenue------14.44%4.3%
Research & Development13.39M14.19M20.95M37.88M23.9M92.42M7.63M9.36M
R&D % of Revenue------13.08%6.23%
Other Operating Expenses0000-271.68K-16.4M0-9.36M
Operating Income+-15.85M-16.49M-29.54M-52.81M-37.45M-113.39M-15.47M-14.32M
Operating Margin %-------26.53%-9.53%
Operating Income Growth %--0.04%-0.79%-0.79%0.29%-2.03%0.86%0.07%
EBITDA+-15.84M-16.48M-29.37M-52.58M-37.17M-113.39M-15.46M-14.3M
EBITDA Margin %-------26.52%-9.52%
EBITDA Growth %--0.04%-0.78%-0.79%0.29%-2.05%0.86%0.08%
D&A (Non-Cash Add-back)7.93K8.32K170.25K229.61K271.68K4.4K7.05K22.32K
EBIT-15.19M-15.53M-28.06M-53.48M-37.13M-37.37M-14.29M-14.32M
Net Interest Income+00-156.35K01.65K01.22M1.29M
Interest Income000222.65K1.65K448.67K1.22M1.29M
Interest Expense15182156.35K222.65K0448.67K00
Other Income/Expense662.13K961.13K1.48M-667.6K319.05K730.2K1.19M1.36M
Pretax Income+-15.19M-15.53M-28.06M-53.48M-37.13M-112.66M-14.29M-12.96M
Pretax Margin %-------24.5%-8.62%
Income Tax+00000000
Effective Tax Rate %1%1%1%1.01%0.98%1%1%1%
Net Income+-15.19M-15.53M-28.06M-53.92M-36.54M-112.66M-14.29M-12.96M
Net Margin %-------24.5%-8.62%
Net Income Growth %--0.02%-0.81%-0.92%0.32%-2.08%0.87%0.09%
Net Income (Continuing)-15.19M-15.53M-28.06M-53.48M-37.13M-112.66M-14.29M-12.96M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)+-21.58-22.06-26.28-50.61-34.88-1359.79-3.95-2.35
EPS Growth %--0.02%-0.19%-0.93%0.31%-37.98%1%0.41%
EPS (Basic)-21.58-22.06-26.28-50.61-34.88-1359.79-3.95-2.35
Diluted Shares Outstanding703.78K703.78K1M1.06M1.06M82.85K3.62M5.51M
Basic Shares Outstanding703.78K703.78K1M1.06M1.06M82.85K3.62M5.51M
Dividend Payout Ratio--------

Balance Sheet

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+24.73M66M133.04M92.42M56.58M30.15M22.52M23.58M
Cash & Short-Term Investments24.4M65.68M130.09M89.02M53.08M28.79M21.61M22.85M
Cash Only24.4M65.68M130.09M89.02M53.08M28.79M21.61M22.85M
Short-Term Investments00000000
Accounts Receivable00000000
Days Sales Outstanding--------
Inventory00000000
Days Inventory Outstanding--------
Other Current Assets000001.37M914.27K726.25K
Total Non-Current Assets+30.46K24.56K563.14K388.51K239.05K2.32K129.08K403.35K
Property, Plant & Equipment30.34K24.45K563.03K359.13K209.68K2.32K88.36K81.52K
Fixed Asset Turnover------6.60x18.43x
Goodwill00000000
Intangible Assets00000000
Long-Term Investments00000040.72K40.17K
Other Non-Current Assets12111110729.38K29.37K00281.66K
Total Assets+24.76M66.02M133.61M92.81M56.82M30.16M22.65M23.98M
Asset Turnover------0.03x0.06x
Asset Growth %-1.67%1.02%-0.31%-0.39%-0.47%-0.25%0.06%
Total Current Liabilities+4.3M4.87M9.06M15.33M7.32M3.2M4.39M3.36M
Accounts Payable1.66M1.74M2.18M4.5M1.77M842.75K1.67M1.35M
Days Payables Outstanding76.47K76.34K4.67K7.16K2.38K18.7586.46K52.71
Short-Term Debt00000000
Deferred Revenue (Current)000000528.97K0
Other Current Liabilities1.92M2.5M961.79K1.52M1.42M960.36K1.17M465.01K
Current Ratio5.75x13.56x14.68x6.03x7.73x9.42x5.14x7.01x
Quick Ratio5.75x13.56x14.68x6.03x7.73x9.42x5.14x7.01x
Cash Conversion Cycle--------
Total Non-Current Liabilities+56.23M112.59M302.62K78.85K01.31M1.31M1.31M
Long-Term Debt00000000
Capital Lease Obligations00302.62K78.85K0000
Deferred Tax Liabilities00000000
Other Non-Current Liabilities56.23M112.59M0001.31M1.31M1.31M
Total Liabilities60.53M117.46M9.36M15.41M7.32M4.51M4.39M4.67M
Total Debt+00544.95K335.16K190.47K000
Net Debt-24.4M-65.68M-129.54M-88.68M-52.89M-28.79M-21.61M-22.85M
Debt / Equity--0.00x0.00x0.00x---
Debt / EBITDA--------
Net Debt / EBITDA--------
Interest Coverage-999999.00x-90601.12x-188.96x-237.19x--252.73x--
Total Equity+-35.77M-51.44M124.24M77.4M49.51M25.64M18.26M19.31M
Equity Growth %--0.44%3.42%-0.38%-0.36%-0.48%-0.29%0.06%
Book Value per Share-50.82-73.09123.6473.2446.51309.515.053.50
Total Shareholders' Equity-35.77M-51.44M124.24M77.4M49.51M25.64M18.26M19.31M
Common Stock126.84K127.09K21.02K21.19K1.09K2.65K3.74K5.48K
Retained Earnings-46.94M-62.47M-90.53M-144.01M-181.13M-293.8M-308.08M-321.04M
Treasury Stock00000000
Accumulated OCI-8.29M-8.76M-11.53M-10.04M-10.36M-10.62M-10.61M-10.63M
Minority Interest00000000

Cash Flow

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-14M-15.25M-26.71M-41.8M-37.69M-25.01M-12.18M-13.56M
Operating CF Margin %-------20.88%-9.02%
Operating CF Growth %--0.09%-0.75%-0.57%0.1%0.34%0.51%-0.11%
Net Income-15.19M-15.53M-28.06M-53.48M-37.13M-112.66M-14.29M-12.96M
Depreciation & Amortization7.93K8.32K170.25K229.61K271.68K186.44K7.05K22.32K
Stock-Based Compensation395.44K329.18K1.35M4.98M7.81M16.98M444.46K489.44K
Deferred Taxes00000000
Other Non-Cash Items-662.14K-961.32K-1.33M890.25K-317.4K72.24M38.93K-54.37K
Working Capital Changes1.45M901.85K1.16M5.57M-8.33M-1.76M1.62M-1.06M
Change in Receivables00000000
Change in Inventory00000000
Change in Payables327.05K214.38K437.51K2.33M-2.73M-858.51K827.46K-314.21K
Cash from Investing+0-3.7K-30.9K-25.71K00-93.09K-15.48K
Capital Expenditures0-3.7K-30.9K-25.71K00-93.09K-15.48K
CapEx % of Revenue------0.16%0.01%
Acquisitions--------
Investments--------
Other Investing00000000
Cash from Financing+23.34M56.37M92.58M150.95K1.75M682.97K5.14M14.82M
Debt Issued (Net)--------
Equity Issued (Net)--------
Dividends Paid00000000
Share Repurchases--------
Other Financing02.1K71K0208.37K0-648.93K-1.32M
Net Change in Cash--------
Free Cash Flow+-14M-15.25M-26.74M-41.83M-37.69M-25.01M-12.27M-13.57M
FCF Margin %-------21.04%-9.03%
FCF Growth %--0.09%-0.75%-0.56%0.1%0.34%0.51%-0.11%
FCF per Share-19.90-21.67-26.61-39.58-35.41-301.88-3.39-2.46
FCF Conversion (FCF/Net Income)0.92x0.98x0.95x0.78x1.03x0.22x0.85x1.05x
Interest Paid00000000
Taxes Paid00000000

Key Ratios

Metric20172018201920202021202220232024
Return on Equity (ROE)---77.08%-53.48%-57.58%-299.83%-65.08%-68.98%
Gross Margin------98.79%-523.16%
Net Margin-------2449.59%-862.43%
Debt / Equity--0.00x0.00x0.00x---
Interest Coverage-999999.00x-90601.12x-188.96x-237.19x--252.73x--
FCF Conversion0.92x0.98x0.95x0.78x1.03x0.22x0.85x1.05x
Revenue Growth-------157.63%

Frequently Asked Questions

Growth & Financials

Aprea Therapeutics, Inc. (APRE) reported $0.5M in revenue for fiscal year 2024.

Aprea Therapeutics, Inc. (APRE) grew revenue by 157.6% over the past year. This is strong growth.

Aprea Therapeutics, Inc. (APRE) reported a net loss of $13.0M for fiscal year 2024.

Dividend & Returns

Aprea Therapeutics, Inc. (APRE) has a return on equity (ROE) of -69.0%. Negative ROE indicates the company is unprofitable.

Aprea Therapeutics, Inc. (APRE) had negative free cash flow of $13.5M in fiscal year 2024, likely due to heavy capital investments.

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