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Anavex Life Sciences Corp. (AVXL) 10-Year Financial Performance & Capital Metrics

AVXL • • Industrial / General
HealthcareBiotechnologyNeurology & CNS DisordersAlzheimer's & Neurodegenerative
AboutAnavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of drug candidates for the treatment of central nervous system (CNS) diseases. Its lead drug candidate is ANAVEX 2-73, which is in Phase III clinical trial for the treatment of Alzheimer's disease; Phase III clinical trial to treat pediatric patients with Rett syndrome; Phase II clinical trial for the treatment of Parkinson's disease; and preclinical clinical trials to treat epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. The company's drug candidate also comprises ANAVEX 3-71, which is in Phase I clinical trial for the treatment of frontotemporal dementia and other dementia indications; and preclinical clinical trials for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Its preclinical drug candidates include ANAVEX 1-41, a sigma-1 receptor agonist for the treatment of depression, stroke, Parkinson's, and Alzheimer's diseases; ANAVEX 1066, a mixed sigma-1/sigma-2 ligand for the potential treatment of neuropathic and visceral pain; and ANAVEX 1037 to treat prostate and pancreatic cancer. The company was incorporated in 2004 and is headquartered in New York, New York.Show more
  • Revenue $0
  • EBITDA $0 +100.0%
  • Net Income $0 +100.0%
  • EPS (Diluted) -0.54 -3.8%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -
  • ROIC -
  • Debt/Equity -
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Weak momentum: RS Rating 5 (bottom 5%)
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-15.99%

EPS CAGR

10Y-
5Y-
3Y-
TTM-14%

ROCE

10Y Avg-87.09%
5Y Avg-40.35%
3Y Avg-39.78%
Latest-

Peer Comparison

Alzheimer's & Neurodegenerative
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Profit & Loss

Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Sales/Revenue+000-685K000000
Revenue Growth %----1%-----
Cost of Goods Sold+1.25K000000000
COGS % of Revenue----------
Gross Profit+-1.25K000000000
Gross Margin %----------
Gross Profit Growth %-1%--------
Operating Expenses+14.88M15.54M19.18M29.11M30.94M41.95M50.99M55.76M52.88M51.41M
OpEx % of Revenue----42.49%------
Selling, General & Admin8.33M5.01M6.14M6.85M5.86M9.15M13.07M12.04M11.04M13.82M
SG&A % of Revenue----10%------
Research & Development7.25M10.67M13.34M22.26M25.23M32.98M37.92M43.72M41.84M37.59M
R&D % of Revenue----32.5%------
Other Operating Expenses151.4K000-151K-186K0000
Operating Income+-15.59M-15.54M-19.18M-28.75M-31.09M-41.92M-50.99M-55.76M-52.88M0
Operating Margin %---41.97%------
Operating Income Growth %-1.19%0%-0.23%-0.5%-0.08%-0.35%-0.22%-0.09%0.05%1%
EBITDA+-15.59M-15.54M-1.68M-2.11M-30.63M-4.47M-54.31M-58.47M-2.29M0
EBITDA Margin %---3.08%------
EBITDA Growth %-1.19%0%0.89%-0.26%-13.51%0.85%-11.16%-0.08%0.96%1%
D&A (Non-Cash Add-back)1.25K1.25K17.5M26.64M037.45M-3.32M-2.72M50.59M0
EBIT-15.02M-15.42M-18.98M-28.53M-30.63M-42.19M-50.94M-53.04M-45.29M0
Net Interest Income+-11.31M0224.15K56.15K179.97K26.26K05.55M7.32M0
Interest Income11.32K88.1K255.09K207.28K179.97K26.26K946.99K6.52M7.32M0
Interest Expense11.32M030.94K151.13K00946.99K964K00
Other Income/Expense881.96K2.28M2.1M3.08M4.83M4.28M3.37M8.26M9.88M0
Pretax Income+-14.71M-13.4M-17.18M-26.21M-26.26M-37.64M-47.62M-47.5M-43M0
Pretax Margin %---38.27%------
Income Tax+29.61K59.61K72.75K82.18K22.66K267.56K358.49K7K00
Effective Tax Rate %1%1%1.02%1%1%1.01%1.01%1%1%-
Net Income+-14.74M-13.46M-17.45M-26.3M-26.28M-37.91M-47.98M-47.51M-43M0
Net Margin %---38.39%------
Net Income Growth %-0.22%0.09%-0.3%-0.51%0%-0.44%-0.27%0.01%0.09%1%
Net Income (Continuing)-14.74M-13.46M-17.25M-26.3M-26.28M-37.91M-47.98M-47.51M-43M0
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-0.42-0.33-0.39-0.54-0.45-0.54-0.62-0.60-0.52-0.54
EPS Growth %0.35%0.21%-0.18%-0.38%0.17%-0.2%-0.15%0.03%0.13%-0.04%
EPS (Basic)-0.42-0.33-0.39-0.54-0.45-0.54-0.62-0.60-0.52-0.54
Diluted Shares Outstanding35.15M40.84M44.66M48.91M58.2M69.8M76.91M79.79M83.47M85.29M
Basic Shares Outstanding35.15M40.84M44.66M48.91M58.2M69.8M76.91M79.79M83.47M85.29M
Dividend Payout Ratio----------

Balance Sheet

Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Total Current Assets+9.45M27.79M24.32M25.33M34.54M161.62M152.7M154.39M135.57M103.81M
Cash & Short-Term Investments9.19M27.44M22.93M22.19M29.25M152.11M149.16M151.02M132.19M102.58M
Cash Only9.19M27.44M22.93M22.19M29.25M152.11M149.16M151.02M132.19M102.58M
Short-Term Investments0000000000
Accounts Receivable79.35K9.75K1.87M2.64M4.85M9.14M3.19M2.71M2.45M809K
Days Sales Outstanding----1.41K------
Inventory000-2.64M016.36K0000
Days Inventory Outstanding----------
Other Current Assets0002.64M0-16.36K162653K931K429K
Total Non-Current Assets+52.4K52.4K52.4K05.29M16.36K3.55B3.36M00
Property, Plant & Equipment0000000000
Fixed Asset Turnover----------
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments0000000000
Other Non-Current Assets52.4K52.4K52.4K05.29M16.36K3.55B3.36M00
Total Assets+9.5M27.84M24.38M25.33M34.54M161.62M152.7M154.39M135.57M103.81M
Asset Turnover----0.03x------
Asset Growth %-0.39%1.93%-0.12%0.04%0.36%3.68%-0.06%0.01%-0.12%-0.23%
Total Current Liabilities+3.19M3.58M3.88M5.04M7.31M10.8M10.21M12.53M15.3M8.95M
Accounts Payable3.06M3.58M2.96M3.52M3.99M4.74M3.82M4.32M9.63M4.25M
Days Payables Outstanding892.31K---------
Short-Term Debt0000000000
Deferred Revenue (Current)70.53K0000443.83K443.83K0842K805K
Other Current Liabilities70.53K00000-476.85M1.53M1.56M
Current Ratio2.96x7.75x6.26x5.03x4.73x14.97x14.95x12.32x8.86x11.60x
Quick Ratio2.96x7.75x6.26x5.55x4.73x14.97x14.95x12.32x8.86x11.60x
Cash Conversion Cycle----------
Total Non-Current Liabilities+0000000000
Long-Term Debt0000000000
Capital Lease Obligations0000000000
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities0000000000
Total Liabilities3.19M3.58M3.88M5.04M7.31M10.8M10.21M12.53M15.3M8.95M
Total Debt+0000000000
Net Debt-9.19M-27.44M-22.93M-22.19M-29.25M-152.11M-149.16M-151.02M-132.19M-102.58M
Debt / Equity----------
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-1.38x--620.01x-190.24x---53.84x-57.84x--
Total Equity+6.31M24.25M20.49M20.29M27.24M150.82M142.49M141.85M120.26M94.87M
Equity Growth %-0.51%2.84%-0.16%-0.01%0.34%4.54%-0.06%-0%-0.15%-0.21%
Book Value per Share0.180.590.460.410.472.161.851.781.441.11
Total Shareholders' Equity6.31M24.25M20.49M20.29M27.24M150.82M142.49M141.85M120.26M94.87M
Common Stock36.17K43.33K45.94K52.65K62.05K75.92K77.94K82K85K87K
Retained Earnings-78.02M-91.48M-108.93M-133.4M-159.68M-197.59M-245.56M-293.07M-336.07M-382.45M
Treasury Stock0000000000
Accumulated OCI0000000000
Minority Interest0000000000

Cash Flow

Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Cash from Operations+-9.24M-9.02M-12.58M-18.53M-21.29M-30.38M-24.24M-27.79M-30.81M-39.04M
Operating CF Margin %---27.05%------
Operating CF Growth %-1.19%0.02%-0.4%-0.47%-0.15%-0.43%0.2%-0.15%-0.11%-0.27%
Net Income-14.74M-13.46M-17.45M-26.29M-26.28M-37.91M-47.98M-47.51M-43M-46.38M
Depreciation & Amortization1.25K000000000
Stock-Based Compensation5.06M4.14M5.52M6.43M4.88M8.23M18.38M16.37M9.44M11.55M
Deferred Taxes-58.14K000000000
Other Non-Cash Items-145.57K-75.2K5.61M35.38K0403242845K0-4.22M
Working Capital Changes640.07K382.81K-646K1.3M116.52K-706.44K5.36M2.5M2.75M0
Change in Receivables-2.51K54.44K-231.1K-772.39K-2.21M-4.29M5.94M484K260K0
Change in Inventory000772.39K2.21M4.29M-5.94M000
Change in Payables-151.4M554.71K38.23K683.8K465.72K750.73K-915K497K5.3M-5.38M
Cash from Investing+0000000000
Capital Expenditures0000000000
CapEx % of Revenue----------
Acquisitions----------
Investments----------
Other Investing0000000000
Cash from Financing+3.13M27.27M8.07M17.78M28.35M153.24M21.29M29.65M11.97M9.43M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing3.13M0-101.13K-50K-403.76K23.4K01.78M691K9.43M
Net Change in Cash----------
Free Cash Flow+-9.24M-9.02M-12.58M-18.53M-21.29M-30.38M-24.24M-27.79M-30.81M-39.04M
FCF Margin %---27.05%------
FCF Growth %-1.19%0.02%-0.4%-0.47%-0.15%-0.43%0.2%-0.15%-0.11%-0.27%
FCF per Share-0.26-0.22-0.28-0.38-0.37-0.44-0.32-0.35-0.37-0.46
FCF Conversion (FCF/Net Income)0.63x0.67x0.72x0.70x0.81x0.80x0.51x0.58x0.72x-
Interest Paid0000000000
Taxes Paid000022.66K140K327K136K300K0

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-154.18%-88.08%-78.01%-128.96%-110.59%-42.58%-32.71%-33.41%-32.81%-
Net Margin---3838.69%------
Interest Coverage-1.38x--620.01x-190.24x---53.84x-57.84x--
FCF Conversion0.63x0.67x0.72x0.70x0.81x0.80x0.51x0.58x0.72x-
Revenue Growth----100%-----

Frequently Asked Questions

Growth & Financials

Anavex Life Sciences Corp. (AVXL) grew revenue by 0.0% over the past year. Growth has been modest.

Anavex Life Sciences Corp. (AVXL) reported a net loss of $48.2M for fiscal year 2025.

Dividend & Returns

Anavex Life Sciences Corp. (AVXL) had negative free cash flow of $37.1M in fiscal year 2025, likely due to heavy capital investments.

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