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Axsome Therapeutics, Inc. (AXSM) 10-Year Financial Performance & Capital Metrics

AXSM • • Industrial / General
HealthcareBiotechnologyNeurology & CNS DisordersPsychiatric & CNS Disorders
AboutAxsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.Show more
  • Revenue $386M +42.5%
  • EBITDA -$273M -21.2%
  • Net Income -$287M -20.1%
  • EPS (Diluted) -5.99 -13.7%
  • Gross Margin 91.37% +1.1%
  • EBITDA Margin -70.68% +15.0%
  • Operating Margin -72.74% +15.1%
  • Net Margin -74.47% +15.8%
  • ROE -231.63% -45.5%
  • ROIC -
  • Debt/Equity 3.38 +246.8%
  • Interest Coverage -42.71 -18.9%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 86 (top 14%)
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗High debt to equity ratio of 3.4x
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Expensive at 148.8x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM65.83%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM26.19%

EPS CAGR

10Y-
5Y-
3Y-
TTM28.48%

ROCE

10Y Avg-93.52%
5Y Avg-84.79%
3Y Avg-86.33%
Latest-71.23%

Peer Comparison

Psychiatric & CNS Disorders
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Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+000000050.04M270.6M385.69M
Revenue Growth %--------4.41%0.43%
Cost of Goods Sold+3.54K20.48K42.56K48.94K37.33K005.2M26.07M33.3M
COGS % of Revenue-------0.1%0.1%0.09%
Gross Profit+-3.54K-20.48K-42.56K-48.94K-37.33K0044.84M244.53M352.39M
Gross Margin %-------0.9%0.9%0.91%
Gross Profit Growth %--4.78%-1.08%-0.15%0.24%1%--4.45%0.44%
Operating Expenses+9.2M27.54M27.16M32.85M67.11M99.14M124.71M224.64M476.36M632.95M
OpEx % of Revenue-------4.49%1.76%1.64%
Selling, General & Admin2.42M6.34M7.21M9.35M13.6M28.9M66.65M159.25M323.12M411.36M
SG&A % of Revenue-------3.18%1.19%1.07%
Research & Development6.78M21.2M19.96M23.5M53.65M70.24M58.06M57.95M97.94M187.08M
R&D % of Revenue-------1.16%0.36%0.49%
Other Operating Expenses0000-139.45K-53.58K07.44M55.29M34.52M
Operating Income+-9.2M-27.54M-27.16M-32.85M-67.25M-99.14M-124.71M-179.8M-231.82M-280.56M
Operating Margin %--------3.59%-0.86%-0.73%
Operating Income Growth %-0.62%-2%0.01%-0.21%-1.05%-0.47%-0.26%-0.44%-0.29%-0.21%
EBITDA+-9.19M-27.52M-27.12M-32.8M-67.21M-99.06M-124.63M-175.4M-224.99M-272.6M
EBITDA Margin %--------3.51%-0.83%-0.71%
EBITDA Growth %-2.35%-1.99%0.01%-0.21%-1.05%-0.47%-0.26%-0.41%-0.28%-0.21%
D&A (Non-Cash Add-back)3.54K20.48K42.56K48.94K37.33K77.72K76K4.4M6.83M7.96M
EBIT-9.2M-27.54M-27.81M-32.63M-67.25M-100.39M-124.71M-179.8M-231.82M-280.56M
Net Interest Income+0-132.42K-1.34M-1.13M00-5.7M-7.33M-6.45M-6.57M
Interest Income914.95K0001.24M2.57M0000
Interest Expense914.95K132.42K1.34M1.13M1.24M2.57M5.7M7.33M6.45M6.57M
Other Income/Expense-1.36M341.86K-1.78M1.66M-1.1M-3.76M-5.7M-7.33M-6.45M-6.57M
Pretax Income+-10.56M-27.2M-28.94M-30.97M-68.35M-102.9M-130.4M-187.13M-238.28M-287.13M
Pretax Margin %--------3.74%-0.88%-0.74%
Income Tax+1.36M0000000960K85K
Effective Tax Rate %1.16%1%1%1%1%1%1%1%1%1%
Net Income+-12.21M-27.2M-28.94M-30.97M-68.35M-102.9M-130.4M-187.13M-239.24M-287.22M
Net Margin %--------3.74%-0.88%-0.74%
Net Income Growth %-1.03%-1.23%-0.06%-0.07%-1.21%-0.51%-0.27%-0.44%-0.28%-0.2%
Net Income (Continuing)-12.21M-27.2M-28.94M-30.97M-68.35M-102.9M-130.4M-187.13M-239.24M-287.22M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-0.88-1.42-1.27-1.15-2.05-2.83-3.47-4.60-5.27-5.99
EPS Growth %-0.87%-0.61%0.11%0.09%-0.78%-0.38%-0.23%-0.33%-0.15%-0.14%
EPS (Basic)-0.88-1.42-1.27-1.15-2.05-2.83-3.47-4.60-5.27-5.99
Diluted Shares Outstanding11.95M19.15M22.76M26.88M34.02M37.21M37.62M40.66M45.43M47.91M
Basic Shares Outstanding11.95M19.15M22.76M26.88M34.02M37.21M37.62M40.66M45.43M47.91M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+49.03M38M35.3M15.22M220.38M184.02M86.52M245.64M504.26M485.06M
Cash & Short-Term Investments48.04M36.62M34.02M13.97M219.97M183.88M86.47M200.84M386.19M315.35M
Cash Only48.04M36.62M34.02M13.97M219.97M183.88M86.47M200.84M386.19M315.35M
Short-Term Investments0000000000
Accounts Receivable000000037.7M94.82M142M
Days Sales Outstanding-------275127.9134.38
Inventory00000004.32M15.13M15.73M
Days Inventory Outstanding-------303.35211.94172.42
Other Current Assets00000002.78M8.12M11.98M
Total Non-Current Assets+43.28K213.55K256.02K164.18K170.5K2.11M1.27M85.83M83.97M83.43M
Property, Plant & Equipment16.65K100.73K68.07K51.83K30.62K1.79M944.01K1.14M7.62M5.97M
Fixed Asset Turnover-------43.82x35.52x64.64x
Goodwill000000010.31M12.04M12.04M
Intangible Assets000000059.66M53.29M46.89M
Long-Term Investments0000000000
Other Non-Current Assets26.63K112.82K187.95K112.34K139.88K317.38K322.91K14.72M11.03M18.53M
Total Assets+49.08M38.21M35.56M15.38M220.55M186.13M87.79M331.48M588.24M568.5M
Asset Turnover-------0.15x0.46x0.68x
Asset Growth %16.61%-0.22%-0.07%-0.57%13.34%-0.16%-0.53%2.78%0.77%-0.03%
Total Current Liabilities+2.63M7.17M12.18M10.82M24.49M23.44M23.07M96.56M138.85M230.1M
Accounts Payable1.89M4.08M3.44M3.69M10.94M13.5M13.15M38.6M40.68M72M
Days Payables Outstanding195.01K72.72K29.46K27.5K107K--2.71K569.65789.09
Short-Term Debt0269.16K3.27M3.29M2.6M00000
Deferred Revenue (Current)001000K0000000
Other Current Liabilities00444.29K0004.05M17.18M76.45M36.51M
Current Ratio18.63x5.30x2.90x1.41x9.00x7.85x3.75x2.54x3.63x2.11x
Quick Ratio18.63x5.30x2.90x1.41x9.00x7.85x3.75x2.50x3.52x2.04x
Cash Conversion Cycle--------2.13K-229.81-482.28
Total Non-Current Liabilities+09.47M6.66M3.62M17.33M48.9M49.09M125.36M258.4M281.38M
Long-Term Debt09.47M6.66M3.62M17.33M48.32M49.09M94.26M178.07M180.71M
Capital Lease Obligations00000581.71K007.04M8.99M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities000000031.1M73.3M91.68M
Total Liabilities2.63M16.64M18.84M14.44M41.83M72.34M72.15M221.92M397.26M511.48M
Total Debt+09.74M9.93M6.91M19.93M50.12M49.71M94.68M186.37M192.96M
Net Debt-48.04M-26.88M-24.09M-7.06M-200.03M-133.75M-36.76M-106.16M-199.82M-122.4M
Debt / Equity-0.45x0.59x7.37x0.11x0.44x3.18x0.86x0.98x3.38x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-10.05x-207.99x-20.27x-29.14x-54.25x-38.64x-21.89x-24.51x-35.93x-42.71x
Total Equity+46.44M21.57M16.72M937.92K178.72M113.79M15.63M109.56M190.98M57.02M
Equity Growth %15.5%-0.54%-0.23%-0.94%189.55%-0.36%-0.86%6.01%0.74%-0.7%
Book Value per Share3.891.130.730.035.253.060.422.694.201.19
Total Shareholders' Equity46.44M21.57M16.72M937.92K178.72M113.79M15.63M109.56M190.98M57.02M
Common Stock1.92K1.92K2.55K3.01K3.69K3.74K3.78K4K5K5K
Retained Earnings-20.44M-47.64M-76.58M-107.55M-175.9M-278.8M-409.2M-596.33M-835.57M-1.12B
Treasury Stock0000000000
Accumulated OCI0000000000
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-7.44M-21.28M-26.47M-30.05M-46.38M-78.46M-108.23M-116.51M-145.08M-128.41M
Operating CF Margin %--------2.33%-0.54%-0.33%
Operating CF Growth %-0.62%-1.86%-0.24%-0.14%-0.54%-0.69%-0.38%-0.08%-0.25%0.11%
Net Income-10.56M-27.2M-28.94M-30.97M-68.35M-102.9M-130.4M-187.13M-239.24M-287.22M
Depreciation & Amortization3.54K20.48K42.56K48.94K37.33K77.72K76K4.4M6.83M0
Stock-Based Compensation803.28K2.03M2.07M1.75M6.12M14.76M20.8M37.73M62.62M85.22M
Deferred Taxes2.28M0646K-2.79M01.25M0000
Other Non-Cash Items-902.22K68.93K470.52K375.63K649.99K7.95M974K4.83M53.1M39.69M
Working Capital Changes937.73K3.8M-759.55K1.52M15.17M412.04K324K23.67M-28.39M33.9M
Change in Receivables00000177.5K0-37.7M-57.12M-47.18M
Change in Inventory00000-177.5K-6K-5.28M-8.16M744K
Change in Payables1.13M2.19M-645.72K251.79K7.26M2.56M-355K25.46M2.07M31.32M
Cash from Investing+-20.2K-104.56K-9.9K-32.7K-16.12K-45.89K-308K-53.7M-582K-270K
Capital Expenditures-20.2K-104.56K-9.9K-32.7K-16.12K-45.89K-308K-702K-582K-270K
CapEx % of Revenue-------0.01%0%0%
Acquisitions----------
Investments----------
Other Investing0000000000
Cash from Financing+52.88M9.97M23.88M10.03M252.39M42.41M11.13M284.58M331.01M57.84M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing-12.49K-64.93K484.61K486.03K1.39M-52.76K3.69M-4.18M-12.74M18.05M
Net Change in Cash----------
Free Cash Flow+-7.46M-21.39M-26.48M-30.09M-46.39M-78.5M-108.53M-117.21M-145.66M-128.68M
FCF Margin %--------2.34%-0.54%-0.33%
FCF Growth %-0.62%-1.87%-0.24%-0.14%-0.54%-0.69%-0.38%-0.08%-0.24%0.12%
FCF per Share-0.62-1.12-1.16-1.12-1.36-2.11-2.89-2.88-3.21-2.69
FCF Conversion (FCF/Net Income)0.61x0.78x0.91x0.97x0.68x0.76x0.83x0.62x0.61x0.45x
Interest Paid0000004.63M7.69M00
Taxes Paid0000000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-56.48%-79.99%-151.19%-350.78%-76.08%-70.36%-201.51%-298.97%-159.21%-231.63%
Gross Margin-------89.61%90.37%91.37%
Net Margin--------373.99%-88.41%-74.47%
Debt / Equity-0.45x0.59x7.37x0.11x0.44x3.18x0.86x0.98x3.38x
Interest Coverage-10.05x-207.99x-20.27x-29.14x-54.25x-38.64x-21.89x-24.51x-35.93x-42.71x
FCF Conversion0.61x0.78x0.91x0.97x0.68x0.76x0.83x0.62x0.61x0.45x
Revenue Growth--------440.8%42.53%

Revenue by Segment

202220232024
Product-202.46M381.68M
Product Growth--88.52%
License-65.73M-
License Growth---
Royalty-2.4M-
Royalty Growth---

Revenue by Geography

202220232024
UNITED STATES49.13M197.22M378.16M
UNITED STATES Growth-301.42%91.74%
Non-US905K65.73M4.02M
Non-US Growth-7163.54%-93.89%

Frequently Asked Questions

Growth & Financials

Axsome Therapeutics, Inc. (AXSM) reported $561.3M in revenue for fiscal year 2024.

Axsome Therapeutics, Inc. (AXSM) grew revenue by 42.5% over the past year. This is strong growth.

Axsome Therapeutics, Inc. (AXSM) reported a net loss of $229.5M for fiscal year 2024.

Dividend & Returns

Axsome Therapeutics, Inc. (AXSM) has a return on equity (ROE) of -231.6%. Negative ROE indicates the company is unprofitable.

Axsome Therapeutics, Inc. (AXSM) had negative free cash flow of $101.0M in fiscal year 2024, likely due to heavy capital investments.

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