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CLNNClene Inc.
$6.06$62M
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CLNN logoClene Inc.(CLNN)Earnings, Financials & Key Ratios

CLNN•NASDAQ
$6.06
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutClene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug is CNM-Au8, which is being studied in various clinical trials, including a Phase 2/3 registrational clinical trial for patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; ongoing Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a planned Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. The company's products also include CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to accelerate wound healing; CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease, such as COVID-19 and to provide immune support for symptom resolution; and CNM-PtAu7, a gold-platinum CSN therapeutic for oncology applications. It also markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. The company is headquartered in Salt Lake City, Utah.Show more
  • Revenue$200K-41.5%
  • EBITDA-$22M+31.4%
  • Net Income-$26M+33.6%
  • EPS (Diluted)-2.65+53.3%
  • Gross Margin78.5%-1.3%
  • EBITDA Margin-10794%-17.4%
  • Operating Margin-11541.5%-19.3%
  • Net Margin-13086.5%-13.6%

CLNN Price & Volume

Clene Inc. (CLNN) stock price & volume — 10-year historical chart

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Clene Faces Severe Liquidity And Solvency Risks

Investment Thesis • Updated 2026Q1

VerdictNeutral
Growth:Contracting
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Insolvency and dilutive financing
"Clene Inc. faces a precarious financial outlook characterized by a negligible revenue base of $15,000 in 2026Q1 and a persistent inability to achieve operational profitability. The company's reliance on high-cost R&D spending, which frequently exceeds $5 million per quarter, has led to a rapid erosion of shareholder equity into a negative $18.8 million position. Investors should remain cautious as the firm's dwindling cash reserves of $5.9 million suggest an imminent requirement for dilutive financing or potential insolvency."

Verdict Logic

Negative: The company's negative equity position of -$18.8 million and the rapid depletion of cash reserves to $5.9 million indicate a high probability of significant shareholder dilution or insolvency.

CLNN Growth Metrics

Clene Inc. (CLNN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-0.59%
3 Years-24.94%
TTM-61.71%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-15.28%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM24.68%

Return on Capital

10 Years-99.52%
5 Years-135.7%
3 Years-160.02%
Last Year-189.2%

CLNN Recent Earnings

Clene Inc. (CLNN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 4/12 qtrs (33%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$0.69-8.4%
$0.64
Rev
$15,000-70.4%
$50,750
Q2 2026
Mar 12, 2026
Metric
Actual
Est
EPS
$0.88-18.9%
$0.74
Rev
$77,000+196.2%
$26,000
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.85-41.7%
$0.60
Rev
$15,000-76.7%
$64,333
Q3 2025
Aug 14, 2025
Metric
Actual
Est
EPS
$0.78-59.2%
$0.49
Rev
$27,000-51.0%
$55,140
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.69vs $0.64-8.4%
$15,000vs $50,750-70.4%
Q2 2026Mar 12, 2026
$0.88vs $0.74-18.9%
$77,000vs $26,000+196.2%
Q4 2025Nov 13, 2025
$0.85vs $0.60-41.7%
$15,000vs $64,333-76.7%
Q3 2025Aug 14, 2025
$0.78vs $0.49-59.2%
$27,000vs $55,140-51.0%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Clene Inc. (CLNN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CLNN logoCLNNClene Inc.Current
$6.06$62.46M-2.29-41.52%-13086.5%——
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.32$4.34B11.0611.87%34.3%35.65%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$327.79$9.47B-24.32-100%—-43.02%—
SAVA logoSAVACassava Sciences, Inc.
$1.32$63.77M-2.54——-95.77%—
ACIU logoACIUAC Immune S.A.
$2.56$260.54M-2.96-86.92%-1971.7%-101.76%—
NRXP logoNRXPNRx Pharmaceuticals, Inc.
$3.73$64.48M-2.78—-1070.26%——

Compare CLNN vs Peers

Clene Inc. (CLNN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for CLNN.

Scale Benchmark

vs LLY

Larger-name benchmark to compare CLNN against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, PRAX, SAVA, ACIU

CLNN SEC Filings & Documents

Clene Inc. (CLNN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 22, 2026·SEC

Material company update

May 14, 2026·SEC

Material company update

May 5, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 24, 2025·SEC

10-Q Quarterly Reports

5
FY 2026

May 14, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 14, 2025·SEC

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CLNN Frequently Asked Questions

Clene Inc. (CLNN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Clene Inc.'s revenue?

Clene Inc. (CLNN) reported $0.1M in revenue for fiscal year 2025.

How fast is Clene Inc. growing?

Clene Inc. (CLNN) saw revenue decline by 41.5% over the past year.

Is CLNN profitable?

Clene Inc. (CLNN) reported a net loss of $33.5M for fiscal year 2025.

Dividend & Returns
What is Clene Inc.'s free cash flow?

Clene Inc. (CLNN) had negative free cash flow of $18.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CLNN back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →