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Clene Inc. (CLNN) 10-Year Financial Performance & Capital Metrics

CLNN • • Industrial / General
HealthcareBiotechnologyNeurology & CNS DisordersAlzheimer's & Neurodegenerative
AboutClene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug is CNM-Au8, which is being studied in various clinical trials, including a Phase 2/3 registrational clinical trial for patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; ongoing Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a planned Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. The company's products also include CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to accelerate wound healing; CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease, such as COVID-19 and to provide immune support for symptom resolution; and CNM-PtAu7, a gold-platinum CSN therapeutic for oncology applications. It also markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. The company is headquartered in Salt Lake City, Utah.Show more
  • Revenue $342K -47.7%
  • EBITDA -$31M +19.0%
  • Net Income -$39M +20.4%
  • EPS (Diluted) -5.67 +39.9%
  • Gross Margin 79.53% -2.4%
  • EBITDA Margin -9195.32% -54.9%
  • Operating Margin -9676.32% -56.1%
  • Net Margin -11520.47% -52.2%
  • ROE -1738.36% -191.9%
  • ROIC -299.74% -64.9%
  • Debt/Equity -
  • Interest Coverage -8.14 +8.4%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 32.5% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-22.08%
TTM-49.17%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM15.35%

EPS CAGR

10Y-
5Y-
3Y-
TTM34.43%

ROCE

10Y Avg-86.71%
5Y Avg-109.9%
3Y Avg-133.77%
Latest-150.23%

Peer Comparison

Alzheimer's & Neurodegenerative
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
ANVSAnnovis Bio, Inc.84.81M3.20-0.00-189.15%
CLNNClene Inc.60.19M5.11-0.90-47.71%-142.5%-17.38%
ABOSAcumen Pharmaceuticals, Inc.112.67M1.86-1.09-143.12%0.16
BHVNBiohaven Ltd.1.58B11.92-1.28-198.83%0.09
IKTInhibikase Therapeutics, Inc.200.09M1.65-1.42-100%-65.37%0.00
ALECAlector, Inc.198.66M1.82-1.483.6%-156.03%-186.68%0.34
CGTXCognition Therapeutics, Inc.121.82M1.38-1.62-76.61%0.04
ATHEAlterity Therapeutics Limited60M3.31-2.9035.32%-330.63%-73.75%0.00

Profit & Loss

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+00206K723K473K654K342K
Revenue Growth %---2.51%-0.35%0.38%-0.48%
Cost of Goods Sold+0900K65K289K26K121K70K
COGS % of Revenue--0.32%0.4%0.05%0.19%0.2%
Gross Profit+0-900K141K434K447K533K272K
Gross Margin %--0.68%0.6%0.95%0.81%0.8%
Gross Profit Growth %--1.16%2.08%0.03%0.19%-0.49%
Operating Expenses+323.94K15.43M20.36M50.41M48.86M41.07M33.37M
OpEx % of Revenue--98.81%69.73%103.29%62.8%97.56%
Selling, General & Admin323.94K6.67M3.26M18.81M16.16M14.42M13.31M
SG&A % of Revenue--15.83%26.02%34.17%22.05%38.91%
Research & Development6.64M8.76M15.2M28.42M31.92M26.66M20.06M
R&D % of Revenue--73.81%39.3%67.48%40.76%58.65%
Other Operating Expenses001.89M3.18M773K00
Operating Income+-323.94K-16.33M-20.21M-49.98M-48.41M-40.54M-33.09M
Operating Margin %---98.13%-69.13%-102.34%-61.99%-96.76%
Operating Income Growth %--49.42%-0.24%-1.47%0.03%0.16%0.18%
EBITDA+348.06K-15.43M-19.25M-49.02M-47.39M-38.84M-31.45M
EBITDA Margin %---93.45%-67.8%-100.19%-59.38%-91.95%
EBITDA Growth %--45.34%-0.25%-1.55%0.03%0.18%0.19%
D&A (Non-Cash Add-back)672K900K963K955K1.02M1.71M1.65M
EBIT19.43K-16.07M-17.92M-9.3M-26.62M-44.95M-35.34M
Net Interest Income+343.37K-88K-950K-870K-3.3M-3.17M-3.2M
Interest Income343.37K00001.39M865K
Interest Expense088K950K870K3.3M4.56M4.06M
Other Income/Expense343.37K177K1.34M39.81M18.49M-8.96M-6.31M
Pretax Income+19.43K-16.16M-18.87M-10.17M-29.92M-49.5M-39.4M
Pretax Margin %---91.61%-14.06%-63.25%-75.69%-115.2%
Income Tax+00406K-428K000
Effective Tax Rate %-14.27%1%1.02%0.96%1%1%1%
Net Income+-277.31K-16.16M-19.28M-9.74M-29.92M-49.5M-39.4M
Net Margin %---93.58%-13.47%-63.25%-75.69%-115.2%
Net Income Growth %--57.26%-0.19%0.49%-2.07%-0.65%0.2%
Net Income (Continuing)19.43K-16.16M-19.28M-9.74M-29.92M-49.5M-39.4M
Discontinued Operations0000000
Minority Interest0000000
EPS (Diluted)+-0.09-4.69-5.51-3.16-4.69-9.43-5.67
EPS Growth %--51.76%-0.17%0.43%-0.48%-1.01%0.4%
EPS (Basic)-0.09-4.69-5.51-3.16-4.69-9.43-5.67
Diluted Shares Outstanding3.12M3.47M3.5M3.08M3.26M5.25M6.95M
Basic Shares Outstanding3.12M3.47M3.5M3.08M3.26M5.25M6.95M
Dividend Payout Ratio-------

Balance Sheet

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+790.48K9.48M62.99M54.58M29.2M38.85M16.16M
Cash & Short-Term Investments743.78K8.79M59.27M50.29M23.32M35M12.15M
Cash Only743.78K8.79M59.27M50.29M18.33M28.82M12.15M
Short-Term Investments00004.98M6.18M0
Accounts Receivable002.17M1.61M2.97M1.34M391K
Days Sales Outstanding--3.84K814.312.29K746.74417.3
Inventory028K191K41K43K37K68K
Days Inventory Outstanding-11.361.07K51.78603.65111.61354.57
Other Current Assets0248K112K2.45M2.87M2.48M137K
Total Non-Current Assets+46.37M5.4M5.25M8.48M15.3M13.49M11.18M
Property, Plant & Equipment4.47M5.4M5.25M8.42M15.24M13.43M11.12M
Fixed Asset Turnover--0.04x0.09x0.03x0.05x0.03x
Goodwill0000000
Intangible Assets0000000
Long-Term Investments46.37M0058K58K058K
Other Non-Current Assets-4.47M000058K0
Total Assets+47.16M14.88M68.24M63.06M44.49M52.34M27.34M
Asset Turnover--0.00x0.01x0.01x0.01x0.01x
Asset Growth %--0.68%3.59%-0.08%-0.29%0.18%-0.48%
Total Current Liabilities+222.24K4.31M11.67M6.03M13.86M25.33M10.29M
Accounts Payable0889K1.12M1.92M3.01M1.5M1.24M
Days Payables Outstanding-360.546.31K2.43K42.31K4.54K6.47K
Short-Term Debt3M416K006.42M19.5M359K
Deferred Revenue (Current)-1000K80K413K0001000K
Other Current Liabilities68K2.11M7.15M520K02.12M0
Current Ratio3.56x2.20x5.40x9.06x2.11x1.53x1.57x
Quick Ratio3.56x2.19x5.38x9.05x2.10x1.53x1.56x
Cash Conversion Cycle---1.4K-1.56K-39.42K-3.68K-5.69K
Total Non-Current Liabilities+41.94M5.68M56.23M44.44M27.4M13.62M25.9M
Long-Term Debt0640K1.95M19.08M19.25M7.15M15.43M
Capital Lease Obligations224K1.82M1.99M4.47M5.59M4.9M4.13M
Deferred Tax Liabilities-224K0260K0000
Other Non-Current Liabilities39.87M1.37M52.03M20.89M2.56M1.57M6.34M
Total Liabilities42.16M9.99M67.9M50.47M41.26M38.95M36.19M
Total Debt+3.22M2.88M4.32M24.04M31.82M32.16M20.84M
Net Debt2.48M-5.91M-54.95M-26.25M13.49M3.34M8.69M
Debt / Equity0.64x0.59x12.68x1.91x9.83x2.40x-
Debt / EBITDA9.26x------
Net Debt / EBITDA7.13x------
Interest Coverage--185.59x-21.28x-57.45x-14.69x-8.89x-8.14x
Total Equity+5M4.89M341K12.6M3.24M13.39M-8.86M
Equity Growth %--0.02%-0.93%35.94%-0.74%3.14%-1.66%
Book Value per Share1.601.410.104.090.992.55-1.27
Total Shareholders' Equity5M4.89M341K12.6M3.24M13.39M-8.86M
Common Stock1992K6K6K7K13K1K
Retained Earnings17.04K-69.57M-153.56M-163.3M-193.22M-242.72M-282.12M
Treasury Stock-1.33M000000
Accumulated OCI27.18K41K325K233K203K199K71K
Minority Interest0000000

Cash Flow

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-205.37K-13.2M-18.93M-34.62M-39.01M-30.17M-21.33M
Operating CF Margin %---91.89%-47.89%-82.48%-46.13%-62.36%
Operating CF Growth %--63.26%-0.43%-0.83%-0.13%0.23%0.29%
Net Income-277.31K-16.16M-19.28M-9.74M-29.92M-49.5M-39.4M
Depreciation & Amortization672K848K963K955K1.02M1.71M1.65M
Stock-Based Compensation269K399K761K12.38M8.51M9.12M7.95M
Deferred Taxes0000000
Other Non-Cash Items-46.6K554K1.97M-39.23M-17.09M8.7M5.26M
Working Capital Changes118.54K1.16M-3.35M1M-1.54M-191K3.21M
Change in Receivables00-21K-28K-140K46K79K
Change in Inventory0-28K-163K150K-2K6K-31K
Change in Payables0-76K-312K1.27M285K-1.51M-264K
Cash from Investing+-46M-294K-387K-1.33M-10.16M-1.5M6.32M
Capital Expenditures-752K-294K-387K-1.33M-5.18M-330K-15K
CapEx % of Revenue--1.88%1.84%10.95%0.5%0.04%
Acquisitions-------
Investments-------
Other Investing0000000
Cash from Financing+46.95M5.5M69.53M27.11M17.25M42.16M-1.53M
Debt Issued (Net)-------
Equity Issued (Net)-------
Dividends Paid0000000
Share Repurchases-------
Other Financing15.9M610K28.55M-1.98M229K-200K124K
Net Change in Cash-------
Free Cash Flow+-957.37K-13.49M-19.32M-35.96M-44.19M-30.5M-21.34M
FCF Margin %---93.77%-49.73%-93.42%-46.64%-62.4%
FCF Growth %--13.09%-0.43%-0.86%-0.23%0.31%0.3%
FCF per Share-0.31-3.89-5.52-11.68-13.55-5.81-3.07
FCF Conversion (FCF/Net Income)0.74x0.82x0.98x3.55x1.30x0.61x0.54x
Interest Paid048K39K1.09M2.32M3.06M2.61M
Taxes Paid0000000

Key Ratios

Metric2018201920202021202220232024
Return on Equity (ROE)-5.55%-326.79%-737.45%-150.56%-377.9%-595.47%-1738.36%
Return on Invested Capital (ROIC)--379.33%---2357.58%-181.74%-299.74%
Gross Margin--68.45%60.03%94.5%81.5%79.53%
Net Margin---9357.77%-1347.16%-6325.16%-7569.42%-11520.47%
Debt / Equity0.64x0.59x12.68x1.91x9.83x2.40x-
Interest Coverage--185.59x-21.28x-57.45x-14.69x-8.89x-8.14x
FCF Conversion0.74x0.82x0.98x3.55x1.30x0.61x0.54x
Revenue Growth---250.97%-34.58%38.27%-47.71%

Revenue by Segment

20202021202220232024
Product176K570K316K498K237K
Product Growth-223.86%-44.56%57.59%-52.41%
Royalty30K153K144K156K105K
Royalty Growth-410.00%-5.88%8.33%-32.69%

Frequently Asked Questions

Growth & Financials

Clene Inc. (CLNN) reported $0.2M in revenue for fiscal year 2024.

Clene Inc. (CLNN) saw revenue decline by 47.7% over the past year.

Clene Inc. (CLNN) reported a net loss of $30.5M for fiscal year 2024.

Dividend & Returns

Clene Inc. (CLNN) has a return on equity (ROE) of -1738.4%. Negative ROE indicates the company is unprofitable.

Clene Inc. (CLNN) had negative free cash flow of $18.6M in fiscal year 2024, likely due to heavy capital investments.

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