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CRDFCardiff Oncology, Inc.$1.59$109M
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CRDF logoCardiff Oncology, Inc.(CRDF)Earnings, Financials & Key Ratios

CRDF•NASDAQ
Price updated Jun 11, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutCardiff Oncology, Inc., a clinical-stage oncology company, develops medicine treatment for cancer patients in California. Its lead drug candidate is onvansertib, an oral selective Polo-like Kinase 1 Inhibitor for anti-cancer therapeutics; CY140, an inhibitor of PLK1, PLK2, and PLK3 that is in phase 1/2 studies in solid tumors and leukemias; metastatic colorectal cancer that is in clinical trials; and TROV-054 is a Phase 1b/2 for FOLFIRI and bevacizumab. The company's TROV-053 is also in Phase II clinical trial in combination with Zytiga for metastatic castration-resistant prostate cancer. The company primarily serves pharmaceutical manufacturers. The company was formerly known as Trovagene, Inc. and changed its name to Cardiff Oncology, Inc. in May 2012. Cardiff Oncology, Inc. was incorporated in 1999 and is headquartered in San Diego, California.Show more
  • Revenue$593K-13.2%
  • EBITDA-$48M+0.4%
  • Net Income-$46M-0.9%
  • EPS (Diluted)-0.69+27.4%
  • Gross Margin100%
  • EBITDA Margin-8103.88%-14.7%
  • Operating Margin-8256.32%-15.9%
  • Net Margin-7732.04%-16.2%
  • ROE-71.45%-20.1%
  • ROIC-118.93%-35.6%
  • Debt/Equity0.02-0.2%

CRDF Key Insights

Cardiff Oncology, Inc. (CRDF) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y sales CAGR of 10.1%

✗Weaknesses

  • ✗Profits declining 18.9% over 5 years
  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Shares diluted 40.3% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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CRDF Price & Volume

Cardiff Oncology, Inc. (CRDF) stock price & volume — 10-year historical chart

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CRDF Growth Metrics

Cardiff Oncology, Inc. (CRDF) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years6.6%
5 Years10.13%
3 Years15.39%
TTM-10.71%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM8.36%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM35.58%

Return on Capital

10 Years-81.13%
5 Years-48.42%
3 Years-63.04%
Last Year-75.76%

CRDF Recent Earnings

Cardiff Oncology, Inc. (CRDF) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 11/12 qtrs (92%)
Q2 2026Latest
May 14, 2026
EPS
$0.18
Est $0.13
-38.5%
Revenue
$41,000
Est $88,571
-53.7%
Q1 2026
Feb 24, 2026
EPS
$0.11
Est $0.18
+38.9%
Revenue
$243,000
Est $103,500
+134.8%
Q4 2025
Nov 6, 2025
EPS
$0.17
Est $0.20
+15.0%
Revenue
$120,000
Est $103,500
+15.9%
Q3 2025
Jul 29, 2025
EPS
$0.21
Est $0.19
-10.5%
Revenue
$121,000
Est $109,375
+10.6%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.18vs $0.13-38.5%
$41,000vs $88,571-53.7%
Q1 2026Feb 24, 2026
$0.11vs $0.18+38.9%
$243,000vs $103,500+134.8%
Q4 2025Nov 6, 2025
$0.17vs $0.20+15.0%
$120,000vs $103,500+15.9%
Q3 2025Jul 29, 2025
$0.21vs $0.19-10.5%
$121,000vs $109,375+10.6%
Based on last 12 quarters of dataView full earnings history →

CRDF Peer Comparison

Cardiff Oncology, Inc. (CRDF) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
TGTX logoTGTXTG Therapeutics, Inc.Direct Competitor7.36B48.0517.3587.32%65.95%87.36%0.40
MGNX logoMGNXMacroGenics, Inc.Direct Competitor254.89M4.01-3.400.78%-44.79%-147.8%1.92
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.16B59.21-6.09-43.89%-284.18%-87%1.66
IMVT logoIMVTImmunovant, Inc.Direct Competitor6.75B32.88-11.87-68.16%0.00
KPTI logoKPTIKaryopharm Therapeutics Inc.Direct Competitor76.84M9.00-0.500.57%-129.02%
AGIO logoAGIOAgios Pharmaceuticals, Inc.Product Competitor1.71B28.72-4.0348.03%-6.4%-34.11%0.05
AGEN logoAGENAgenus Inc.Product Competitor141.17M3.39-997.0610.37%52.16%
FATE logoFATEFate Therapeutics, Inc.Product Competitor229.62M1.97-1.71-51.24%-20.57%-58.89%0.38

Compare CRDF vs Peers

Cardiff Oncology, Inc. (CRDF) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs TGTX

Most directly comparable listed peer for CRDF.

Scale Benchmark

vs RVMD

Larger-name benchmark to compare CRDF against a more recognizable public peer.

Peer Set

Compare Top 5

vs TGTX, MGNX, NKTR, IMVT

CRDF Income Statement

Cardiff Oncology, Inc. (CRDF) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
505K378K244.63K366K359K386K488K683K593K525K
Revenue Growth %
32.55%-25.15%-35.28%49.61%-1.91%7.52%26.42%39.96%-13.18%-10.71%
Cost of Goods Sold
1.81M597K000000011.8M
COGS % of Revenue
358.61%157.94%--------
Gross Profit
-1.31M▲ 0%
-219K▲ 83.2%
244.63K▲ 211.7%
366K▲ 49.6%
359K▼ 1.9%
386K▲ 7.5%
488K▲ 26.4%
683K▲ 40.0%
593K▼ 13.2%
-11.28M▲ 0%
Gross Margin %
-258.61%-57.94%100%100%100%100%100%100%100%-2147.81%
Gross Profit Growth %
3.19%83.23%211.7%49.61%-1.91%7.52%26.42%39.96%-13.18%-
Operating Expenses
22.11M16.17M16.92M19.45M29.21M40.29M45.9M49.33M49.55M36.15M
OpEx % of Revenue
4379.21%4277.78%6917.79%5314.75%8137.6%10437.31%9405.74%7223.13%8356.32%-
Selling, General & Admin
14.23M8.01M5.76M8.22M11.84M13.18M13.04M12.48M14.22M13.02M
SG&A % of Revenue
2818.22%2117.99%2354.92%2245.08%3297.49%3414.77%2672.75%1827.53%2398.65%-
Research & Development
7.88M8.16M11.16M11.23M17.38M27.11M32.86M36.85M35.33M31.62M
R&D % of Revenue
1560.99%2159.79%4562.87%3069.67%4840.11%7022.54%6732.99%5395.61%5957.67%-
Other Operating Expenses
-170K00000000-1.22M
Operating Income
-25.6M▲ 0%
-17.05M▲ 33.4%
-16.68M▲ 2.2%
-19.09M▼ 14.4%
-28.86M▼ 51.2%
-39.9M▼ 38.3%
-45.41M▼ 13.8%
-48.65M▼ 7.1%
-48.96M▼ 0.6%
-47.43M▲ 0%
Operating Margin %
-5068.51%-4511.38%-6817.79%-5214.75%-8037.6%-10337.31%-9305.74%-7123.13%-8256.32%-9033.9%
Operating Income Growth %
36.24%33.38%2.2%-14.43%-51.18%-38.28%-13.81%-7.13%-0.64%-
EBITDA
-24.54M-16.32M-16.18M-18.62M-28.4M-39.67M-45.01M-48.25M-48.06M-46.4M
EBITDA Margin %
-4859.82%-4316.64%-6615.76%-5087.43%-7911.98%-10276.17%-9224.18%-7063.98%-8103.88%-8837.33%
EBITDA Growth %
37.19%33.51%0.81%-15.05%-52.55%-39.65%-13.48%-7.18%0.4%10.03%
D&A (Non-Cash Add-back)
1.05M736.09K494.23K466K451K236K398K404K904K1.03M
EBIT
-23.87M-16.44M-16.41M-19.3M-28.86M-39.9M-45.41M-48.65M-48.96M-46.71M
Net Interest Income
-886.06K194.02K234.17K88K264K1.58M4.07M3.26M3.1M2.67M
Interest Income
147.88K219.43K234.17K90K264K1.58M4.07M3.26M3.1M2.67M
Interest Expense
1.03M25.41K02K000000
Other Income/Expense
689.05K-72.45K264.33K-221K564K1.2M3.97M3.22M3.11M2.67M
Pretax Income
-24.91M▲ 0%
-16.46M▲ 33.9%
-16.41M▲ 0.3%
-19.31M▼ 17.6%
-28.29M▼ 46.5%
-38.7M▼ 36.8%
-41.44M▼ 7.1%
-45.43M▼ 9.6%
-45.85M▼ 0.9%
-44.77M▲ 0%
Pretax Margin %
-4932.08%-4354.76%-6709.74%-5275.14%-7880.5%-10026.94%-8492.01%-6651.68%-7732.04%-8527.24%
Income Tax
716K617.64K00000000
Effective Tax Rate %
-2.87%-3.75%0%0%0%0%0%0%0%0%
Net Income
-24.91M▲ 0%
-16.46M▲ 33.9%
-16.41M▲ 0.3%
-19.31M▼ 17.6%
-28.29M▼ 46.5%
-38.7M▼ 36.8%
-41.44M▼ 7.1%
-45.43M▼ 9.6%
-45.85M▼ 0.9%
-44.77M▲ 0%
Net Margin %
-4932.08%-4354.76%-6709.74%-5275.14%-7880.5%-10026.94%-8492.01%-6651.68%-7732.04%-8527.24%
Net Income Growth %
36.47%33.91%0.28%-17.62%-46.53%-36.81%-7.07%-9.63%-0.92%8.36%
Net Income (Continuing)
-24.91M-16.46M-16.41M-19.31M-28.29M-38.7M-41.44M-45.43M-45.85M-44.77M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-51.71▲ 0%
-7.06▲ 86.3%
-2.70▲ 61.8%
-1.08▲ 60.0%
-0.73▲ 32.4%
-0.89▼ 21.9%
-0.93▼ 4.5%
-0.95▼ 2.2%
-0.69▲ 27.4%
-0.66▲ 0%
EPS Growth %
44.53%86.35%61.76%60%32.41%-21.92%-4.49%-2.15%27.37%35.58%
EPS (Basic)
-51.71-7.06-2.70-1.08-0.73-0.89-0.93-0.95-0.69-
Diluted Shares Outstanding
481.67K2.33M5.97M20.88M39.03M43.6M44.68M47.65M66.84M68.35M
Basic Shares Outstanding
481.67K2.33M5.97M20.88M39.03M43.6M44.68M47.65M66.84M68.35M
Dividend Payout Ratio
----------

CRDF Balance Sheet

Cardiff Oncology, Inc. (CRDF) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
9.47M12.77M11.35M133.36M146.13M111.28M77.41M95.05M60.13M47.34M
Cash & Short-Term Investments
8.23M11.45M10.2M130.98M140.82M105.27M74.82M91.75M58.3M46.06M
Cash Only
8.23M11.45M10.2M130.98M11.94M16.35M21.66M51.47M17.47M8.54M
Short-Term Investments
0000128.88M88.92M53.17M40.28M40.83M37.51M
Accounts Receivable
77.09K167.75K203.48K320K535K771K288K773K182K191K
Days Sales Outstanding
55.72161.99303.6319.13543.94729.05215.41413.1112.02200.4
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
000005.25M2.3M2.54M1.64M1.09M
Total Non-Current Assets
2.82M1.41M1.73M1.37M3.42M4.91M4.22M2.14M1.76M1.83M
Property, Plant & Equipment
2.43M1.3M1.58M967K3.18M3.52M2.95M2.07M1.21M986K
Fixed Asset Turnover
0.21x0.29x0.16x0.38x0.11x0.11x0.17x0.33x0.49x0.40x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
0000000000
Other Non-Current Assets
390K103K157.58K404K239K1.39M1.28M69K549K844K
Total Assets
12.29M▲ 0%
14.17M▲ 15.4%
13.09M▼ 7.7%
134.73M▲ 929.5%
149.54M▲ 11.0%
116.19M▼ 22.3%
81.64M▼ 29.7%
97.19M▲ 19.1%
61.88M▼ 36.3%
49.17M▲ 0%
Asset Turnover
0.04x0.03x0.02x0.00x0.00x0.00x0.01x0.01x0.01x0.01x
Asset Growth %
-72.05%15.36%-7.66%929.51%11%-22.3%-29.74%19.05%-36.33%-62.27%
Total Current Liabilities
3.95M2.96M4.78M6.12M6.56M7.81M10.44M13.43M16.39M14.46M
Accounts Payable
825.24K664.84K656.3K1.37M1.44M1.96M1.97M4.82M8.09M5.48M
Days Payables Outstanding
166.32406.48-------170.25
Short-Term Debt
1.33M000000000
Deferred Revenue (Current)
-11000000000
Other Current Liabilities
651.2K827.65K1M1.56M1.48M1.85M5.05M2.75M7.58M8.34M
Current Ratio
2.40x4.31x2.37x21.79x22.28x14.25x7.41x7.08x3.67x3.27x
Quick Ratio
2.40x4.31x2.37x21.79x22.28x14.25x7.41x7.08x3.67x3.27x
Cash Conversion Cycle
---------30.15
Total Non-Current Liabilities
1.83M1.12M993.46K450K2.57M2.04M1.46M813K102K0
Long-Term Debt
0000000000
Capital Lease Obligations
00860.96K9K2.57M2.04M1.46M813K102K850K
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
1.83M1.12M132.5K441K000000
Total Liabilities
5.78M4.09M5.78M6.57M9.13M9.85M11.9M14.24M16.5M14.46M
Total Debt
1.33M01.73M869K3.12M2.71M2.15M1.52M832K646K
Net Debt
-6.89M-11.45M-8.47M-130.11M-8.82M-13.63M-19.51M-49.95M-16.64M-7.9M
Debt / Equity
0.20x-0.24x0.01x0.02x0.03x0.03x0.02x0.02x0.02x
Debt / EBITDA
----------0.01x
Net Debt / EBITDA
---------0.17x
Interest Coverage
-23.09x-646.85x--9652.50x------
Total Equity
6.51M▲ 0%
10.08M▲ 55.0%
7.31M▼ 27.5%
128.16M▲ 1652.9%
140.42M▲ 9.6%
106.34M▼ 24.3%
69.74M▼ 34.4%
82.95M▲ 18.9%
45.39M▼ 45.3%
34.71M▲ 0%
Equity Growth %
-67.09%55%-27.5%1652.87%9.57%-24.27%-34.42%18.94%-45.28%-85.66%
Book Value per Share
13.514.331.226.143.602.441.561.740.680.51
Total Shareholders' Equity
6.51M10.08M7.31M128.16M140.42M106.34M69.74M82.95M45.39M34.71M
Common Stock
5.28K7.74K8.31K4K4K4K4K7K7K7K
Retained Earnings
-173.05M-192.19M-208.9M-231.5M-259.81M-298.1M-339.54M-384.18M-430.03M-442.38M
Treasury Stock
0000000000
Accumulated OCI
-2.07M-2.11M00-142K-395K-67K34K50K-49K
Minority Interest
0000000000

CRDF Cash Flow Statement

Cardiff Oncology, Inc. (CRDF) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-23.28M-13.2M-13.27M-16.32M-23.04M-33.82M-30.89M-37.69M-37.92M-37.42M
Operating CF Margin %
-4610.1%-3492.06%-5423.66%-4457.65%-6417.83%-8761.66%-6329.3%-5518.74%-6395.11%-
Operating CF Growth %
25%43.3%-0.52%-22.96%-41.22%-46.79%8.67%-22.04%-0.61%51.99%
Net Income
-24.91M-16.46M-16.41M-19.31M-28.29M-38.7M-41.44M-45.43M-45.85M-44.77M
Depreciation & Amortization
1.25M859K494K466K451K236K398K404K904K1.17M
Stock-Based Compensation
4.01M2.17M885K1.76M3.23M4.26M4.51M4.76M5.69M5.99M
Deferred Taxes
-1.75M-635K-28K01.32M00000
Other Non-Cash Items
1.24M764K703K1.42M2.03M772K-921K-598K-848K-804K
Working Capital Changes
-3.13M98K1.09M-654K-1.79M-380K6.57M3.17M2.18M994K
Change in Receivables
23.36K19.26M-35.73M-117K-215K-236K483K-484K591K214K
Change in Inventory
0-255.62M-1.42B0000000
Change in Payables
-2.94B236.48M1.46B0719K1.35M2.83M2.98M2.2M5.21M
Cash from Investing
23.96M23K-68K-211K-131.45M38.15M36.2M13.73M1.34M19.18M
Capital Expenditures
-100K-5.1K-68K-211K-205K-892K-582K-80K-44K-44K
CapEx % of Revenue
19.8%1.35%27.8%57.65%57.1%231.09%119.26%11.71%7.42%8.38%
Acquisitions
109.91M5.1K00205K-114K0000
Investments
----------
Other Investing
-101.1M23K00-205K114K00-744K-744K
Cash from Financing
-6.38M16.4M12.08M137.31M35.45M75K053.78M2.58M2.68M
Debt Issued (Net)
-17.24M-1.38M00000000
Equity Issued (Net)
11.73M16.17M8.82M112.3M34.19M75K053.41M2.58M2.66M
Dividends Paid
-24.24M-24.24M-24.24M0-24K-414K0000
Share Repurchases
0000000000
Other Financing
-866.04K25.85M27.5M25.01M1.29M414K0373K025K
Net Change in Cash
-5.69M▲ 0%
3.23M▲ 156.7%
-1.26M▼ 139.0%
120.79M▲ 9701.4%
-119.04M▼ 198.6%
4.4M▲ 103.7%
5.31M▲ 20.5%
29.82M▲ 461.7%
-34M▼ 214.0%
-15.55M▲ 0%
Free Cash Flow
-23.38M▲ 0%
-13.21M▲ 43.5%
-13.34M▼ 1.0%
-16.53M▼ 23.9%
-23.25M▼ 40.7%
-34.71M▼ 49.3%
-31.47M▲ 9.3%
-37.77M▼ 20.0%
-37.97M▼ 0.5%
-37.46M▲ 0%
FCF Margin %
-4629.9%-3493.41%-5451.45%-4515.3%-6474.93%-8992.75%-6448.57%-5530.45%-6402.53%-7135.43%
FCF Growth %
26.62%43.52%-0.99%-23.92%-40.66%-49.33%9.34%-20.03%-0.51%12.37%
FCF per Share
-48.54-5.67-2.23-0.79-0.60-0.80-0.70-0.79-0.57-0.55
FCF Conversion (FCF/Net Income)
0.93x0.80x0.81x0.85x0.81x0.87x0.75x0.83x0.83x0.84x
Interest Paid
668.47K22.48K00000000
Taxes Paid
8008008001K1K2K1K000

CRDF Key Ratios

Cardiff Oncology, Inc. (CRDF) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)-189.59%-198.44%-188.72%-28.5%-21.07%-31.37%-47.07%-59.51%-71.45%-95.51%
Return on Invested Capital (ROIC)-----33.39%-26.68%-47.65%-87.68%-118.93%-98.65%
Gross Margin-258.61%-57.94%100%100%100%100%100%100%100%-2147.81%
Net Margin-4932.08%-4354.76%-6709.74%-5275.14%-7880.5%-10026.94%-8492.01%-6651.68%-7732.04%-8527.24%
Debt / Equity0.20x-0.24x0.01x0.02x0.03x0.03x0.02x0.02x0.02x
Interest Coverage-23.09x-646.85x--9652.50x------
FCF Conversion0.93x0.80x0.81x0.85x0.81x0.87x0.75x0.83x0.83x0.84x
Revenue Growth32.55%-25.15%-35.28%49.61%-1.91%7.52%26.42%39.96%-13.18%-10.71%
Related:CRDF Dividend History·CRDF Revenue History·CRDF Price History·CRDF P/E History·CRDF Financial Ratios·CRDF Institutional Holders

CRDF SEC Filings & Documents

Cardiff Oncology, Inc. (CRDF) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 19, 2026·SEC

Material company update

May 14, 2026·SEC

Material company update

Apr 9, 2026·SEC

10-K Annual Reports

4
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Jul 29, 2025·SEC

CRDF Frequently Asked Questions

Cardiff Oncology, Inc. (CRDF) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Cardiff Oncology, Inc. (CRDF) reported $0.5M in revenue for fiscal year 2025.

Cardiff Oncology, Inc. (CRDF) saw revenue decline by 13.2% over the past year.

Cardiff Oncology, Inc. (CRDF) reported a net loss of $44.8M for fiscal year 2025.

Dividend & Returns

Cardiff Oncology, Inc. (CRDF) has a return on equity (ROE) of -71.5%. Negative ROE indicates the company is unprofitable.

Cardiff Oncology, Inc. (CRDF) had negative free cash flow of $37.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CRDF back in 2005?

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