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Cyclerion Therapeutics, Inc. (CYCN) 10-Year Financial Performance & Capital Metrics

CYCN • • Industrial / General
HealthcareBiotechnologyNeurology & CNS DisordersAlzheimer's & Neurodegenerative
AboutCyclerion Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovering, development, and commercialization of medicines for serious central nervous system (CNS) diseases. Its lead product candidate is CY6463, a CNS-penetrant, soluble guanylate cyclase (sGC) stimulator that is in Phase IIa trials for the treatment of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes, as well as Alzheimer's disease with vascular pathology; and Phase 1 trials diagnosed with schizophrenia in adults. It is also developing Praliciguat, an orally administered systemic sGC stimulator, which is in Phase II studies to treat resistant hypertension and diabetic nephropathy; Olinciguat, an orally administered vascular sGC stimulator that is in Phase II studies for the sickle cell disease; and CY3018 for the treatment of disorders of the CNS. It has license agreement with Akebia Therapeutics, Inc. for the development, manufacture, medical affairs, and commercialization of pharmaceutical products, including pharmaceutical compound, and other related products and forms. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue $2M
  • EBITDA -$4M +71.8%
  • Net Income -$3M +41.9%
  • EPS (Diluted) -1.21 +86.5%
  • Gross Margin 100%
  • EBITDA Margin -181.4%
  • Operating Margin -181.4%
  • Net Margin -152.85%
  • ROE -30.36% +37.3%
  • ROIC -58.3% +97.6%
  • Debt/Equity -
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Trading at only 0.4x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 14 (bottom 14%)
  • ✗Sales declining 15.0% over 5 years
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-15%
3Y-15.54%
TTM1371.65%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM58.36%

EPS CAGR

10Y-
5Y-
3Y-
TTM64.15%

ROCE

10Y Avg-85.51%
5Y Avg-70.91%
3Y Avg-72.78%
Latest-36.03%

Peer Comparison

Alzheimer's & Neurodegenerative
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Profit & Loss

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+004.51M2.3M3.32M297K02M
Revenue Growth %----0.49%0.45%-0.91%-1%-
Cost of Goods Sold+1.75M1.53M95.14M56.41M05.58M00
COGS % of Revenue--21.11%24.57%-18.78%--
Gross Profit+-1.75M-1.53M-90.63M-54.12M3.32M-5.28M02M
Gross Margin %---20.11%-23.57%1%-17.78%-1%
Gross Profit Growth %-0.12%-58.31%0.4%1.06%-2.59%1%-
Operating Expenses+93.92M115.25M34.4M27.15M58.52M13.26M12.95M5.63M
OpEx % of Revenue--7.63%11.82%17.63%44.64%-2.81%
Selling, General & Admin15.12M27.54M34.4M28.82M20.62M13.26M8.33M5.34M
SG&A % of Revenue--7.63%12.55%6.21%44.64%-2.67%
Research & Development78.8M87.72M95.14M56.41M37.64M5.98M1.51M286K
R&D % of Revenue--21.11%24.57%11.34%20.13%-0.14%
Other Operating Expenses00-95.14M-58.08M259K-5.98M3.1M0
Operating Income+-93.92M-115.25M-125.04M-81.27M-55.2M-18.54M-12.95M-3.63M
Operating Margin %---27.74%-35.39%-16.63%-62.42%--1.81%
Operating Income Growth %--0.23%-0.08%0.35%0.32%0.66%0.3%0.72%
EBITDA+-92.18M-113.72M-122.34M-78.97M-54.72M-18.48M-12.89M-3.63M
EBITDA Margin %---27.14%-34.39%-16.48%-62.21%--1.81%
EBITDA Growth %--0.23%-0.08%0.35%0.31%0.66%0.3%0.72%
D&A (Non-Cash Add-back)1.75M1.53M2.7M2.3M472K65K65K0
EBIT-93.92M-115.25M-125.04M-82.93M-54.31M-18.54M-9.65M-3.63M
Net Interest Income+002.03M588K-16K294K358K208K
Interest Income002.03M588K0294K358K208K
Interest Expense000016K000
Other Income/Expense002.03M3.46M3.55M294K358K571K
Pretax Income+-93.92M-115.25M-123.01M-77.8M-51.65M-18.25M-12.59M-3.06M
Pretax Margin %---27.29%-33.89%-15.56%-61.43%--1.53%
Income Tax+00000000
Effective Tax Rate %1%1%1%1%1%2.42%0.42%1%
Net Income+-93.92M-115.25M-123.01M-77.8M-51.65M-44.08M-5.26M-3.06M
Net Margin %---27.29%-33.89%-15.56%-148.41%--1.53%
Net Income Growth %--0.23%-0.07%0.37%0.34%0.15%0.88%0.42%
Net Income (Continuing)-93.92M-115.25M-123.01M-77.8M-51.65M-18.25M-12.59M-3.06M
Discontinued Operations00000-25.83M7.33M0
Minority Interest00000000
EPS (Diluted)+-68.80-84.42-88.37-47.80-26.40-20.15-8.99-1.21
EPS Growth %--0.23%-0.05%0.46%0.45%0.24%0.55%0.87%
EPS (Basic)-68.80-84.42-88.37-47.80-26.40-20.15-8.99-1.21
Diluted Shares Outstanding1.37M1.37M1.37M1.52M1.96M2.17M2.34M2.52M
Basic Shares Outstanding1.37M1.37M1.37M1.52M1.96M2.17M2.34M2.52M
Dividend Payout Ratio--------

Balance Sheet

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+1.26M879K101.2M58.5M55.46M14.82M8.02M4.22M
Cash & Short-Term Investments0097.59M54.4M53.96M13.38M7.57M3.23M
Cash Only0097.59M54.4M53.96M13.38M7.57M3.23M
Short-Term Investments00000000
Accounts Receivable001.47M127K100K96K0556K
Days Sales Outstanding--119.3720.1910.99117.98-101.47
Inventory0000928K000
Days Inventory Outstanding--------
Other Current Assets8K12K162K1.56M468K537K11K16K
Total Non-Current Assets+4.21M6.52M85.28M56.88M3.87M3.26M5.35M5.35M
Property, Plant & Equipment4.13M6.5M79.75M50.27M1.47M1.22M00
Fixed Asset Turnover--0.06x0.05x2.26x0.24x--
Goodwill00000000
Intangible Assets00000000
Long-Term Investments004.99M0005.35M5.35M
Other Non-Current Assets80K25K540K6.61M2.41M2.04M00
Total Assets+5.47M7.4M186.48M115.38M59.33M18.08M13.37M9.57M
Asset Turnover--0.02x0.02x0.06x0.02x-0.21x
Asset Growth %-0.35%24.2%-0.38%-0.49%-0.7%-0.26%-0.28%
Total Current Liabilities+14.04M17.85M18.25M16.95M11.09M7.63M2.09M725K
Accounts Payable1.8M2.78M3.31M1.15M1.83M2.97M1.2M390K
Days Payables Outstanding376.92664.3112.77.43-194.31--
Short-Term Debt003.42M3.51M0000
Deferred Revenue (Current)00000000
Other Current Liabilities5.62M7.27M5.05M176K7.28M68K102K63K
Current Ratio0.09x0.05x5.55x3.45x5.00x1.94x3.85x5.83x
Quick Ratio0.09x0.05x5.55x3.45x4.92x1.94x3.85x5.83x
Cash Conversion Cycle--------
Total Non-Current Liabilities+0070.5M38.93M0000
Long-Term Debt00000000
Capital Lease Obligations0070.5M38.93M0000
Deferred Tax Liabilities00000000
Other Non-Current Liabilities00000000
Total Liabilities14.04M17.85M88.75M55.88M11.09M7.63M2.09M725K
Total Debt+0073.92M45.73M0000
Net Debt00-23.68M-8.66M-53.96M-13.38M-7.57M-3.23M
Debt / Equity--0.76x0.77x----
Debt / EBITDA--------
Net Debt / EBITDA--------
Interest Coverage-----3449.69x---
Total Equity+-8.57M-10.45M97.73M59.49M48.25M10.45M11.29M8.85M
Equity Growth %--0.22%10.36%-0.39%-0.19%-0.78%0.08%-0.22%
Book Value per Share-6.28-7.6571.3939.1424.654.814.833.51
Total Shareholders' Equity-8.57M-10.45M97.73M59.49M48.25M10.45M11.29M8.85M
Common Stock00000000
Retained Earnings00-85.63M-163.43M-215.08M-259.15M-264.42M-267.49M
Treasury Stock00000000
Accumulated OCI-15.87M-15.49M-20K-27K-23K-20K-12K0
Minority Interest00000000

Cash Flow

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-81.22M-97.5M-102.22M-72.49M-36.52M-40.61M-21.25M-4.33M
Operating CF Margin %---22.68%-31.57%-11%-136.74%--2.17%
Operating CF Growth %--0.2%-0.05%0.29%0.5%-0.11%0.48%0.8%
Net Income-93.92M-115.25M-123.01M-77.8M-51.65M-18.25M-12.59M-3.06M
Depreciation & Amortization1.75M1.53M2.7M2.3M472K65K00
Stock-Based Compensation9.49M12.43M19.63M14.99M9.61M00625K
Deferred Taxes00000000
Other Non-Cash Items12.59M14.51M751K-4.38M3.64M-19.58M-4.05M-363K
Working Capital Changes1.47M3.79M-2.29M-7.59M1.41M-2.85M-4.6M-1.54M
Change in Receivables00-1.47M1.35M27K4K96K-556K
Change in Inventory00-3.18M00000
Change in Payables392K979K-250K-1.1M393K1.14M-1.77M-445K
Cash from Investing+-1.4M-3.44M-6.71M18K1.46M010.4M0
Capital Expenditures-1.4M-3.44M-6.89M-1.52M-7K000
CapEx % of Revenue--1.53%0.66%0%---
Acquisitions--------
Investments--------
Other Investing00173K1.54M1.46M000
Cash from Financing+82.62M100.94M211.57M28.09M30.79M29K5.02M0
Debt Issued (Net)--------
Equity Issued (Net)--------
Dividends Paid00000000
Share Repurchases--------
Other Financing82.62M100.94M36.57M331K282K000
Net Change in Cash--------
Free Cash Flow+-82.62M-100.94M-109.1M-74.01M-36.52M-40.61M-21.25M-4.33M
FCF Margin %---24.21%-32.24%-11%-136.74%--2.17%
FCF Growth %--0.22%-0.08%0.32%0.51%-0.11%0.48%0.8%
FCF per Share-60.52-73.94-79.70-48.69-18.66-18.69-9.09-1.72
FCF Conversion (FCF/Net Income)0.86x0.85x0.83x0.93x0.71x0.92x4.04x1.42x
Interest Paid00000000
Taxes Paid00000000

Key Ratios

Metric20172018201920202021202220232024
Return on Equity (ROE)---281.86%-98.97%-95.87%-150.19%-48.42%-30.36%
Return on Invested Capital (ROIC)---294.86%-97.61%-183.5%--2468.42%-58.3%
Gross Margin---2010.94%-2357.06%100%-1778.45%-100%
Net Margin---2729.27%-3388.59%-1555.63%-14841.08%--152.85%
Debt / Equity--0.76x0.77x----
Interest Coverage-----3449.69x---
FCF Conversion0.86x0.85x0.83x0.93x0.71x0.92x4.04x1.42x
Revenue Growth----49.06%44.6%-91.05%-100%-

Revenue by Segment

2024
License Agreement1.75M
License Agreement Growth-
License250K
License Growth-

Frequently Asked Questions

Growth & Financials

Cyclerion Therapeutics, Inc. (CYCN) reported $2.9M in revenue for fiscal year 2024.

Cyclerion Therapeutics, Inc. (CYCN) grew revenue by 0.0% over the past year. Growth has been modest.

Cyclerion Therapeutics, Inc. (CYCN) reported a net loss of $2.2M for fiscal year 2024.

Dividend & Returns

Cyclerion Therapeutics, Inc. (CYCN) has a return on equity (ROE) of -30.4%. Negative ROE indicates the company is unprofitable.

Cyclerion Therapeutics, Inc. (CYCN) had negative free cash flow of $1.4M in fiscal year 2024, likely due to heavy capital investments.

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