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CYTKCytokinetics, Incorporated
$53.69$6.7B
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CYTK logo

Cytokinetics, Incorporated

CYTK
NASDAQ · Metabolic & Cardiovascular Biotech
$53.69
At close - Nov 6, 4:00 PM EST - USD
Market Cap$6.68B
P/E-9.6x
52W High$88.31
Volume2.56M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Revenue Inflection Emerges Amid Persistent Losses and Negative Equity

Cytokinetics' quarterly revenue climbed from $19.4M in 2026Q1 to $47.6M in 2026Q3, and gross margin reached 95.3%, which suggests commercial traction is building off a very small base.

GrowthExpanding
ProfitabilityWeak
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

CYTK price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-123% Peers

P/E is 123% below peer median

03

Market leadership

RS 29 · Lag

Laggard (Underperforming 71% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 4
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue rose 23.6% sequentially to $47.6M in 2026Q3 and gross margin improved to 95.3%, yet operating margin of -3.5% remains far from breakeven after quarters of losses exceeding -86%.

Analyst Consensus+115.3% target
Buy(35 analysts)
34 Buy1 Hold0 Sell

The Bull Case

Upside Catalysts

Bullish investor thesis

A bullish thesis on Cytokinetics, Incorporated highlights potential upside, as discussed on Valueinvestorsclub.com by Bohr.

Late-stage pipeline potential

Cytokinetics' late-stage pipeline, including aficamten, could transition into a globally approved therapy for oHCM, driving growth.

Cardiac myosin focus

The company's focus on developing drugs targeting the sarcomere, specifically cardiac myosin, positions it well in treating debilitating cardiac conditions.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
CYTK-13.02%
S&P 500 (^GSPC)+7.63%
1-Year Return
CYTK-10.96%
S&P 500 (^GSPC)+9.69%
3-Year Return
CYTK+55.94%
S&P 500 (^GSPC)+63.20%
5-Year Return
CYTK+30.95%
S&P 500 (^GSPC)+51.70%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$88M+376.6% YoY
Net income FY25
-$785M-33.2% YoY
Free cash flow FY25
-$535M-33.8% YoY
Operating margin FY25
-695.4%+2207.3 pts YoY
ROIC (FY25)-86.6%
Avg ROIC 5Y-74.7%
ROE (FY25)-
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
Revenue Beat Rate6/12 (50%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 4, 2026
-$1.37+4.2%
vs -$1.43
$48M+13.6%
vs $42M
Q3 2026
Aug 6, 2026
-$1.50+8.0%
vs -$1.63
$29M+62.7%
vs $18M
Q2 2026
May 5, 2026
-$1.67+0.0%
vs -$1.67
$19M+127.2%
vs $9M
Q1 2026
Feb 24, 2026
-$1.50-1.4%
vs -$1.48
$18M+156.3%
vs $7M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Seeking Alpha·3d ago
Cytokinetics, Incorporated (CYTK) Q3 2026 Earnings Call Transcript

Cytokinetics, Incorporated (CYTK) Q3 2026 Earnings Call Transcript

MarketBeat·3d ago
Cytokinetics Q3 Earnings Call Highlights

Cytokinetics NASDAQ: CYTK reported $44.5 million in third-quarter net revenue from heart drug MYQORZO, up 76% from the prior quarter, as the company prepares regulatory submissions that could expand the treatment's use.

Zacks Investment Research·3d ago
Cytokinetics (CYTK) Reports Q3 Loss, Beats Revenue Estimates

Cytokinetics (CYTK) came out with a quarterly loss of $1.37 per share versus the Zacks Consensus Estimate of a loss of $1.5. This compares to a loss of $1.54 per share a year ago.

GlobeNewsWire·3d ago
Cytokinetics Reports Third Quarter 2026 Financial Results and Provides Business Update

MYQORZO ® (aficamten) Net Product Revenue of $44.5 Million Expect to Submit Supplemental NDA for Aficamten in Non-Obstructive HCM in Q4 2026 and Type II Variation in the European Union in Early 2027 ~$1.6 Billion in Cash, Cash Equivalents and Investments as of September 30, 2026 SOUTH SAN FRANCISCO, Calif., Nov. 04, 2026 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) reported a management update and financial results for the third quarter of 2026.

Filtered for Cytokinetics, IncorporatedMore Headlines
04

Compare before deciding

Benchmark CYTK against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Cytokinetics, Incorporated (CYTK)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
CYTK logoCYTKCytokinetics, IncorporatedCurrent
$53.69$6.68B-9.60376.56%-667.26%——
MDGL logoMDGLMadrigal Pharmaceuticals, Inc.
$399.63$9.21B-77.92432.05%-10.89%-27.07%—
KRYS logoKRYSKrystal Biotech, Inc.
$300.88$8.87B41.2133.94%47.91%17.02%—
RCUS logoRCUSArcus Biosciences, Inc.
$18.28$2.3B-5.23-4.26%-445%-90.04%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$21.23$3.64B10.2811.87%30.13%28.03%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$15.43$1.52B-3.0120.13%-71.78%——

Compare CYTK vs Peers

Cytokinetics, Incorporated (CYTK) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs MDGL

Most directly comparable listed peer for CYTK.

Scale Benchmark

vs LLY

Larger-name benchmark to compare CYTK against a more recognizable public peer.

Peer Set

Compare Top 5

vs MDGL, KRYS, RCUS, ACAD

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

CYTK SEC Filings & Documents

Cytokinetics, Incorporated (CYTK) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Nov 4, 2026·SEC

Material company update

Aug 13, 2026·SEC

Material company update

Aug 6, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Nov 4, 2026·SEC

FY 2026

Aug 6, 2026·SEC

FY 2026

May 5, 2026·SEC

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CYTK Frequently Asked Questions

Cytokinetics, Incorporated (CYTK) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Cytokinetics, Incorporated's revenue?

Cytokinetics, Incorporated (CYTK) reported $116.6M in revenue over the trailing twelve months. Revenue was $88.0M in fiscal year 2025. That is 673% more than the $11.4M of fiscal year 2002.

How fast is Cytokinetics, Incorporated growing?

Cytokinetics, Incorporated (CYTK) grew revenue by 33.7% over the trailing twelve months, compared with the twelve months before.

Is CYTK profitable?

No. Cytokinetics, Incorporated (CYTK) reported a net loss of $777.9M over the trailing twelve months.

Dividend & Returns
What is Cytokinetics, Incorporated's free cash flow?

Cytokinetics, Incorporated (CYTK) had negative free cash flow of $588.6M over the trailing twelve months.

What if you invested $1,000 in CYTK back in 2002?

Total return calculator · dividends reinvested · 24+ years of data

See returns →