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GHRS logoGH Research PLC(GHRS)Earnings, Financials & Key Ratios

GHRS•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutGH Research PLC, a clinical-stage biopharmaceutical company, engages in developing various therapies for the treatment of psychiatric and neurological disorders. The company focuses on developing 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) therapies for the treatment of patients with treatment-resistant depression (TRD). Its lead program is GH001, an inhalable 5-MeO-DMT product candidate that has completed two Phase 1 clinical trials and Phase 1/2 clinical trial in patients with TRD. The company also develops GH002, an injectable 5-MeO-DMT product candidate; and GH003, an intranasal 5-MeO-DMT product candidate, which are in preclinical development trials with a focus on psychiatric and neurological disorders. GH Research PLC was incorporated in 2018 and is based in Dublin, Ireland.Show more
  • Revenue$0
  • EBITDA-$60M-20.7%
  • Net Income-$48M-23.9%
  • EPS (Diluted)-0.79-5.3%
  • ROE-21.04%-7.5%

GHRS Key Insights

GH Research PLC (GHRS) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 90 (top 10%)

✗Weaknesses

  • ✗Profits declining 155.2% over 5 years
  • ✗Weak Piotroski F-Score: 3/9
  • ✗Shares diluted 17.3% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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GHRS Price & Volume

GH Research PLC (GHRS) stock price & volume — 10-year historical chart

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GHRS Growth Metrics

GH Research PLC (GHRS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-33.98%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-16.46%

Return on Capital

10 Years-26.24%
5 Years-18.3%
3 Years-23.07%
Last Year-26.43%

GHRS Recent Earnings

GH Research PLC (GHRS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$0.31-14.8%
$0.27
Rev
—
—
Q2 2026
Mar 5, 2026
Metric
Actual
Est
EPS
$0.23+20.7%
$0.29
Rev
—
—
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.23+0.0%
$0.23
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.15+31.8%
$0.22
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$0.31vs $0.27-14.8%
—
Q2 2026Mar 5, 2026
$0.23vs $0.29+20.7%
—
Q4 2025Nov 6, 2025
$0.23vs $0.23+0.0%
—
Q3 2025Aug 7, 2025
$0.15vs $0.22+31.8%
—
Based on last 12 quarters of dataView full earnings history →

GHRS Peer Comparison

GH Research PLC (GHRS) competitors in Neuroscience and Psychiatry Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
CMPS logoCMPSCOMPASS Pathways plcDirect Competitor1.2B12.53-4.07-151.02%
ATAI logoATAIAtai Beckley N.VDirect Competitor1.49B4.06-1.4012.28%-190.19%-366.21%0.01
MNMD logoMNMDMind Medicine (MindMed) Inc.Direct Competitor2.04B20.69-10.04-102.48%
CYBN logoCYBNCybin Inc.Direct Competitor303.86M6.09-13.66-81%
NRXP logoNRXPNRx Pharmaceuticals, Inc.Direct Competitor68.62M3.97-2.96-10.7%
ACAD logoACADACADIA Pharmaceuticals Inc.Product Competitor3.7B21.629.4411.87%34.3%35.65%0.04
AXSM logoAXSMAxsome Therapeutics, Inc.Product Competitor12.89B250.50-68.0765.55%-26.59%-260.01%2.73
INVA logoINVAInnoviva, Inc.Product Competitor1.66B22.496.8218.52%118.91%47.59%0.23

Compare GHRS vs Peers

GH Research PLC (GHRS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CMPS

Most directly comparable listed peer for GHRS.

Scale Benchmark

vs LLY

Larger-name benchmark to compare GHRS against a more recognizable public peer.

Peer Set

Compare Top 5

vs CMPS, ATAI, MNMD, CYBN

GHRS Income Statement

GH Research PLC (GHRS) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
00000000
Revenue Growth %
--------
Cost of Goods Sold
000000335K268K
COGS % of Revenue
--------
Gross Profit
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
-335K▲ 0%
-268K▲ 0%
Gross Margin %
--------
Gross Profit Growth %
--------
Operating Expenses
310K446K15.1M30.55M41.22M50.31M60.34M66.42M
OpEx % of Revenue
--------
Selling, General & Admin
14K108K6.54M10.06M11.12M15M21.61M23.07M
SG&A % of Revenue
--------
Research & Development
296K338K8.55M20.48M29.82M35.02M38.73M43.27M
R&D % of Revenue
--------
Other Operating Expenses
005K14K280K294K075K
Operating Income
-310K▲ 0%
-446K▼ 43.9%
-15.1M▼ 3285.7%
-30.55M▼ 102.3%
-41.22M▼ 34.9%
-50.31M▼ 22.1%
-60.68M▼ 20.6%
-66.69M▲ 0%
Operating Margin %
--------
Operating Income Growth %
--43.87%-3285.65%-102.34%-34.92%-22.05%-20.6%-
EBITDA
00-15.08M-30.51M-40.91M-50M-60.34M-66.34M
EBITDA Margin %
--------
EBITDA Growth %
----102.29%-34.09%-22.22%-20.69%-29.55%
D&A (Non-Cash Add-back)
310K446K19K47K315K315K335K350K
EBIT
-310K-446K-9.19M-22.46M-35.52M-38.91M-60.68M-58.73M
Net Interest Income
00-8.99K01.17M1.91M2.16M1.96M
Interest Income
009-1.89M2.63M2.63M2.32M
Interest Expense
009K-723K717K463K369K
Other Income/Expense
005.9M8.1M5.63M11.35M12.42M10.27M
Pretax Income
-310K▲ 0%
-446K▼ 43.9%
-9.2M▼ 1963.2%
-22.46M▼ 144.0%
-35.59M▼ 58.5%
-38.96M▼ 9.5%
-48.26M▼ 23.9%
-56.41M▲ 0%
Pretax Margin %
--------
Income Tax
00000000
Effective Tax Rate %
0%0%0%0%0%0%0%0%
Net Income
-310K▲ 0%
-446K▼ 43.9%
-9.2M▼ 1963.2%
-22.46M▼ 144.0%
-35.59M▼ 58.5%
-38.96M▼ 9.5%
-48.26M▼ 23.9%
-56.41M▲ 0%
Net Margin %
--------
Net Income Growth %
--43.87%-1963.23%-144.03%-58.47%-9.48%-23.86%-33.98%
Net Income (Continuing)
-310K-446K-9.2M-22.46M-35.59M-38.96M-48.26M-56.41M
Discontinued Operations
00000000
Minority Interest
00000000
EPS (Diluted)
-0.01▲ 0%
-0.01▼ 32.4%
-0.18▼ 1124.5%
-0.14▲ 22.2%
-0.68▼ 385.7%
-0.75▼ 10.3%
-0.79▼ 5.3%
-0.91▲ 0%
EPS Growth %
--32.43%-1124.49%22.22%-385.71%-10.29%-5.33%-16.46%
EPS (Basic)
-0.01-0.01-0.18-0.14-0.68-0.75-0.79-
Diluted Shares Outstanding
28M30.37M52.02M52.02M52.02M52.03M61.04M62.03M
Basic Shares Outstanding
28M30.37M52.02M52.02M52.02M52.03M61.04M62.03M
Dividend Payout Ratio
--------

GHRS Balance Sheet

GH Research PLC (GHRS) balance sheet — assets, liabilities & shareholders' equity

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
504K5.91M279.84M168.54M164.09M154.22M285.98M272.23M
Cash & Short-Term Investments
498K5.89M276.78M165.96M161.56M149.32M280.71M267.32M
Cash Only
498K5.89M276.78M165.96M78.42M100.79M246.25M242.65M
Short-Term Investments
000083.14M48.53M34.46M24.67M
Accounts Receivable
0048K90K178K1.73M1.29M0
Days Sales Outstanding
--------
Inventory
0-6K3.01M-90K0000
Days Inventory Outstanding
--------
Other Current Assets
6K11K10K47K119K004.91M
Total Non-Current Assets
0082K85.82M62.21M34.05M2.25M3.04M
Property, Plant & Equipment
0082K97K1.07M748K620K580K
Fixed Asset Turnover
-------0.00x
Goodwill
00000000
Intangible Assets
00000000
Long-Term Investments
00085.72M61.14M33.3M022.53M
Other Non-Current Assets
0000001.63M2.46M
Total Assets
504K▲ 0%
5.91M▲ 1073.0%
279.92M▲ 4634.8%
254.36M▼ 9.1%
226.3M▼ 11.0%
188.27M▼ 16.8%
288.23M▲ 53.1%
275.27M▲ 0%
Asset Turnover
-------0.00x
Asset Growth %
-1073.02%4634.84%-9.13%-11.03%-16.8%53.09%141.73%
Total Current Liabilities
104K246K2.75M4.55M6.7M8.95M8.38M11.81M
Accounts Payable
93K1K883K1.87M0000
Days Payables Outstanding
-------2.48K
Short-Term Debt
0000343K255K365K357K
Deferred Revenue (Current)
00000000
Other Current Liabilities
00168K312K6.36M8.7M8.02M11.46M
Current Ratio
4.85x24.03x101.80x37.07x24.49x17.23x34.13x23.04x
Quick Ratio
4.85x24.06x100.70x37.09x24.49x17.23x34.13x23.04x
Cash Conversion Cycle
--------
Total Non-Current Liabilities
0001.87M631K369K147K75K
Long-Term Debt
00000000
Capital Lease Obligations
0000631K369K147K722K
Deferred Tax Liabilities
00000000
Other Non-Current Liabilities
00000000
Total Liabilities
104K246K2.75M4.55M7.33M9.32M8.53M11.89M
Total Debt
0000974K624K512K432K
Net Debt
-498K-5.89M-276.78M-165.96M-77.45M-100.17M-245.74M-242.22M
Debt / Equity
----0.00x0.00x0.00x0.00x
Debt / EBITDA
--------0.01x
Net Debt / EBITDA
-------3.65x
Interest Coverage
---1021.44x--49.13x-54.27x-131.05x-159.15x
Total Equity
400K▲ 0%
5.67M▲ 1316.5%
277.18M▲ 4791.9%
249.82M▼ 9.9%
218.97M▼ 12.3%
178.95M▼ 18.3%
279.7M▲ 56.3%
263.38M▲ 0%
Equity Growth %
-1316.5%4791.9%-9.87%-12.35%-18.28%56.3%147.68%
Book Value per Share
0.010.195.334.804.213.444.584.25
Total Shareholders' Equity
400K5.67M277.18M249.82M218.97M178.95M279.7M263.38M
Common Stock
801K871K1.3M1.3M1.3M1.3M1.55M1.55M
Retained Earnings
-389K-835K-10.04M-32.49M-67.94M-106.45M-154.43M-173.23M
Treasury Stock
00000000
Accumulated OCI
-12K200K-5.54M-10.44M-5.86M-7.37M1.52M3.92M
Minority Interest
00000000

GHRS Cash Flow Statement

GH Research PLC (GHRS) cash flow — operating, investing & free cash flow history

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-289K-330K-15.28M-26.2M-33.34M-42.28M-43.55M-46.33M
Operating CF Margin %
--------
Operating CF Growth %
--14.19%-4531.21%-71.43%-27.24%-26.84%-3%-49.37%
Net Income
-310K-446K-9.2M-22.46M-35.59M-38.96M-48.26M-56.41M
Depreciation & Amortization
0019K47K315K315K335K350K
Stock-Based Compensation
00366K1.67M2.29M1.17M01.88M
Deferred Taxes
00-5.92M00000
Other Non-Cash Items
009K-7.62M-2M-5M7.46M8.35M
Working Capital Changes
21K116K-559K2.16M1.65M188K-3.09M-495.64K
Change in Receivables
00000000
Change in Inventory
00000000
Change in Payables
00000000
Cash from Investing
00-104K-84.69M-54.1M65.14M46.17M43.35M
Capital Expenditures
00-104K-67K-100K-49K-121K-181.35K
CapEx % of Revenue
--------
Acquisitions
00000000
Investments
--------
Other Investing
0000000-20.34M
Cash from Financing
797K5.5M286.45M0-204K-304K139.65M-2.23M
Debt Issued (Net)
0000-219K-304K0-63K
Equity Issued (Net)
797K5.5M309.2M015K0139.85M3.43M
Dividends Paid
00000000
Share Repurchases
00000000
Other Financing
00-22.75M000-197K-5.6M
Net Change in Cash
498K▲ 0%
5.4M▲ 983.7%
270.88M▲ 4919.1%
-110.82M▼ 140.9%
-87.53M▲ 21.0%
22.37M▲ 125.6%
145.46M▲ 550.2%
-2.3M▲ 0%
Free Cash Flow
-289K▲ 0%
-330K▼ 14.2%
-15.39M▼ 4562.7%
-26.27M▼ 70.7%
-33.44M▼ 27.3%
-42.33M▼ 26.6%
-43.67M▼ 3.2%
-46.51M▲ 0%
FCF Margin %
--------
FCF Growth %
--14.19%-4562.73%-70.7%-27.3%-26.61%-3.16%-12.62%
FCF per Share
-0.01-0.01-0.30-0.50-0.64-0.81-0.72-0.75
FCF Conversion (FCF/Net Income)
0.93x0.74x1.66x1.17x0.94x1.09x0.90x0.82x
Interest Paid
00000000
Taxes Paid
00000000

GHRS Key Ratios

GH Research PLC (GHRS) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202020212022202320242025TTM
Return on Equity (ROE)
-14.7%-6.51%-8.52%-15.18%-19.58%-21.04%-19.83%
Return on Invested Capital (ROIC)
--13323.53%-54.39%-27.43%-34.26%-80.72%-135.73%
Debt / Equity
---0.00x0.00x0.00x0.00x
Interest Coverage
--1021.44x--49.13x-54.27x-131.05x-159.15x
FCF Conversion
0.74x1.66x1.17x0.94x1.09x0.90x0.82x
Related:GHRS Dividend History·GHRS Revenue History·GHRS Price History·GHRS P/E History·GHRS Financial Ratios·GHRS Institutional Holders

GHRS Frequently Asked Questions

GH Research PLC (GHRS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

GH Research PLC (GHRS) grew revenue by 0.0% over the past year. Growth has been modest.

GH Research PLC (GHRS) reported a net loss of $56.4M for fiscal year 2025.

Dividend & Returns

GH Research PLC (GHRS) has a return on equity (ROE) of -21.0%. Negative ROE indicates the company is unprofitable.

GH Research PLC (GHRS) had negative free cash flow of $46.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in GHRS back in 2019?

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