Last 22 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -2.57 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 1.91 | 7.32 | 6.18 | 3.56 | 1.82 | 1.60 | 0.95 | 3.28 | 14.50 | — | — | — | — |
| — | +356.3% | +550.3% | +8.8% | -87.4% | — | — | — | — | — | — | — | — | |
| P/B Ratio | 0.55 | 1.98 | 1.76 | 2.01 | 2.01 | 1.34 | 0.78 | 1.47 | 0.93 | 2.88 | 2.44 | 0.76 | 0.41 |
| — | +47.9% | +126.4% | +37.2% | +114.8% | -53.4% | -68.1% | +93.6% | +128.7% | +619.8% | +430.8% | -15.8% | -52.3% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Invivyd, Inc.'s operating margin was -313.9% in Q1 2026, down 240.9 pp QoQ and down 164.2 pp YoY. The trailing four-quarter average of -149.6% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind. Gross margin contracted 4.2% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 93.0% | 88.8% | 93.4% | 91.7% | 94.2% | 92.6% | 94.8% | 91.3% | 96.1% | — | — | — | — |
| — | -4.2% | -1.5% | +0.4% | -2.0% | — | — | — | — | — | — | — | — | |
| Operating Margin | -104.0% | -313.9% | -73.0% | -84.0% | -127.8% | -149.7% | -139.1% | -670.0% | -2175.2% | — | — | — | — |
| — | -109.7% | +47.6% | +87.5% | +94.1% | — | — | — | — | — | — | — | — | |
| Net Margin | -98.2% | -301.2% | -64.3% | -79.7% | -124.4% | -144.1% | -133.5% | -653.1% | -2086.9% | — | — | — | — |
| — | -109.0% | +51.8% | +87.8% | +94.0% | — | — | — | — | — | — | — | — |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -34.0% | -18.6% | -6.6% | -15.4% | -30.2% | -26.8% | -24.5% | -54.3% | -29.6% | -24.4% | -34.7% | -14.9% | -16.5% |
| — | +30.4% | +73.0% | +71.6% | -2.2% | -9.5% | +29.6% | -263.4% | -79.3% | -136.2% | -185.8% | -31.2% | -41.6% | |
| ROA | -25.8% | -16.0% | -5.3% | -9.2% | -15.2% | -14.0% | -12.7% | -35.8% | -24.1% | -19.6% | -29.2% | -13.4% | -15.1% |
| — | -14.3% | +58.0% | +74.4% | +36.8% | +28.6% | +56.7% | -168.0% | -59.5% | -103.2% | -164.8% | -34.7% | -54.0% | |
| ROIC | -494.9% | -144.2% | -67.0% | -76.5% | -126.8% | -393.0% | — | — | — | — | -249.0% | -28.1% | -22.1% |
| — | +63.3% | — | — | — | — | — | — | — | — | -1168.6% | +82.7% | — |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has improved 323.4% YoY to 6.47x, strengthening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.01 | 0.04 | 0.01 | 0.03 | 0.07 | 0.02 | 0.02 | 0.02 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 |
| — | +157.3% | -46.5% | +46.5% | +1331.1% | +67.5% | +58.3% | +88.7% | -53.9% | -3.7% | +16.6% | +160.8% | +52.4% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 7.24 | 6.47 | 7.24 | 2.47 | 1.33 | 1.53 | 1.62 | 1.92 | 4.71 | 5.77 | 4.47 | 10.08 | 9.54 |
| — | +323.4% | +345.9% | +28.2% | -71.7% | -73.5% | -63.7% | -80.9% | -50.6% | -63.0% | -70.3% | +10.3% | +34.5% | |
| Quick Ratio | 6.50 | 5.67 | 6.50 | 2.47 | 1.32 | 1.52 | 1.62 | 1.58 | 4.57 | 5.77 | 4.47 | 10.08 | 9.54 |
| — | +273.0% | +300.0% | +56.2% | -71.0% | -73.7% | -63.7% | -84.3% | -52.1% | -63.1% | -70.3% | +10.3% | +34.5% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | -20.63 | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
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Invivyd, Inc.'s current P/E is -2.6x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Invivyd, Inc.'s current operating margin is -104.0%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Invivyd, Inc.'s business trajectory between earnings reports.