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MREOMereo BioPharma Group plc
$0.30$47M
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MREO logoMereo BioPharma Group plc(MREO)Earnings, Financials & Key Ratios

MREO•NASDAQ
$0.30
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutMereo BioPharma Group plc, a biopharmaceutical company, develops and commercializes therapeutics for the treatment of oncology and rare diseases in the United Kingdom and internationally. Its lead product candidate, etigilimab (OMP-313M32), an antibody T-cell immunoreceptor with Ig and ITIM domains, which is in Phase 1b clinical trial for the treatment of tumor. The company is also developing Navicixizumab (OMP-305B83), which has completed Phase 1b clinical trials for the treatment of the late line ovarian cancer; Acumapimod (BCT-197), a p38 MAP kinase inhibitor that is in Phase II clinical trials to treat acute exacerbations of chronic obstructive pulmonary disease; and Leflutrozole (BGS-649), an oral aromatase inhibitor for the treatment of hypogonadotropic hypogonadism. In addition, it develops rare disease product candidates, including Setrusumab (BPS-804), a novel antibody for the treatment of osteogenesis imperfecta; and Alvelestat (MPH-966), an oral small molecule that is in Phase II clinical trial to treat Alpha-1 antitrypsin deficiency. The company has a collaboration with The University of Texas MD Anderson Cancer Center to evaluate anti-TIGIT therapeutic antibody candidate, etigilimab. Mereo BioPharma Group plc was incorporated in 2015 and is based in London, the United Kingdom.Show more
  • Revenue$500K
  • EBITDA-$37M+19.8%
  • Net Income-$42M+3.2%
  • EPS (Diluted)-0.26+10.3%
  • Gross Margin73.4%
  • EBITDA Margin-7421.6%
  • Operating Margin-7651.4%
  • Net Margin-8375.6%
  • ROE-82.21%-6.0%

MREO Price & Volume

Mereo BioPharma Group plc (MREO) stock price & volume — 10-year historical chart

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Persistent Clinical Burn Challenges Mereo BioPharma Liquidity

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Liquidity and clinical execution
"Mereo BioPharma remains a high-risk, pre-revenue biotechnology entity characterized by a reliance on sporadic milestone payments and a significant quarterly R&D expenditure averaging $4.5 million. The company's long-term viability is increasingly constrained by a shrinking asset base, which has declined from $96.1 million in 2024Q2 to $40.6 million as of 2026Q1. Investors should monitor the potential for dilutive financing or strategic out-licensing as the current cash position of $36.2 million faces ongoing pressure from consistent negative free cash flow."

Verdict Logic

the company's reliance on stock-based compensation exceeding $1.5 million per quarter and a rapid depletion of assets from $96.1 million to $40.6 million over two years suggests significant risk to shareholder value.

MREO Growth Metrics

Mereo BioPharma Group plc (MREO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM24.24%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM99.95%

Return on Capital

10 Years-57.31%
5 Years-56.19%
3 Years-68.11%
Last Year-73.46%

MREO Recent Earnings

Mereo BioPharma Group plc (MREO) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (30%)●Beat Revenue 0/12 qtrs (0%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.01-150.0%
$0.02
Rev
—
$12M
Q2 2026
Mar 19, 2026
Metric
Actual
Est
EPS
$0.01+0.0%
$0.01
Rev
—
$23M
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.01-20.0%
$0.01
Rev
$300,000-94.3%
$5M
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.02-100.0%
$0.01
Rev
$685,710
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.01vs $0.02-150.0%
—vs $12M
Q2 2026Mar 19, 2026
$0.01vs $0.01+0.0%
—vs $23M
Q4 2025Nov 10, 2025
$0.01vs $0.01-20.0%
$300,000vs $5M-94.3%
Q3 2025Aug 12, 2025
$0.02vs $0.01-100.0%
$685,710
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Mereo BioPharma Group plc (MREO)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MREO logoMREOMereo BioPharma Group plcCurrent
$0.30$47.34M-1.14—-8375.6%-82.21%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$30.77$3.03B-5.2820.13%-91.03%——
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
KRYS logoKRYSKrystal Biotech, Inc.
$372.25$10.97B54.4233.94%53.92%19.25%—
ACRS logoACRSAclaris Therapeutics, Inc.
$5.00$602.98M-9.43-58.19%-832.58%-55.89%—
ARDX logoARDXArdelyx, Inc.
$5.55$1.36B-21.3522.09%-13.58%-38.11%—

Compare MREO vs Peers

Mereo BioPharma Group plc (MREO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RARE

Most directly comparable listed peer for MREO.

Scale Benchmark

vs PFE

Larger-name benchmark to compare MREO against a more recognizable public peer.

Peer Set

Compare Top 5

vs RARE, FOLD, KRYS, ACRS

MREO SEC Filings & Documents

Mereo BioPharma Group plc (MREO) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 14, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

Mar 27, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 19, 2026·SEC

FY 2025

Mar 26, 2025·SEC

FY 2024

Mar 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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MREO Frequently Asked Questions

Mereo BioPharma Group plc (MREO) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Mereo BioPharma Group plc's revenue?

Mereo BioPharma Group plc (MREO) reported $0.5M in revenue for fiscal year 2025.

Is MREO profitable?

Mereo BioPharma Group plc (MREO) reported a net loss of $35.7M for fiscal year 2025.

Dividend & Returns
What is MREO's return on equity?

Mereo BioPharma Group plc (MREO) has a return on equity (ROE) of -82.2%. Negative ROE indicates the company is unprofitable.

What is Mereo BioPharma Group plc's free cash flow?

Mereo BioPharma Group plc (MREO) had negative free cash flow of $27.0M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MREO back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →