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NAUTNautilus Biotechnolgy, Inc.
$0.95$121M
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NAUT logo

Nautilus Biotechnolgy, Inc.

NAUT
NASDAQ · Biotechnology
$0.95
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$121M
P/E-2.0x
52W High$4.31
Volume385.7K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Pre-Revenue Proteomics Platform Faces Liquidity Constraints

Nautilus Biotechnology remains a high-risk, pre-commercial entity with no revenue generation over the last ten quarters, necessitating a critical evaluation of its ability to reach market viability. The company's heavy reliance on R&D, which averaged $10.8 mil...

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

NAUT price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

12/12 Beats

EPS beat 12 of last 12 quarters

02

Valuation risk

-105% Peers

P/E is 105% below peer median

03

Market leadership

RS 5 · Lag

Laggard (Underperforming 95% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Oct 28

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
NAUT-50.06%
S&P 500 (^GSPC)+12.39%
1-Year Return
NAUT+31.52%
S&P 500 (^GSPC)+15.77%
3-Year Return
NAUT-70.74%
S&P 500 (^GSPC)+72.20%
5-Year Return
NAUT-85.91%
S&P 500 (^GSPC)+72.72%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$59M+16.6% YoY
Free cash flow
-$52M+15.2% YoY
Operating margin
-
ROIC (TTM)-26%
Avg ROIC 5Y-
ROE (TTM)-32.3%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate12/12 (100%)
Revenue Beat Rate1/12 (100%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 28, 2026
-$0.11+18.5%
vs -$0.14
$190,000+90.0%
vs $100,000
Q2 2026
Apr 28, 2026
-$0.12+17.2%
vs -$0.14
—
vs $250,000
Q1 2026
Feb 26, 2026
-$0.11+21.4%
vs -$0.14
—
vs $1M
Q4 2025
Oct 27, 2025
-$0.11+26.7%
vs -$0.15
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GlobeNewsWire·Sep 4, 2026
Nature Methods Publication Reveals Deep Insights into Functional Biology through First-of-its-Kind Quantification of Tau Proteoforms

First large-scale, single-molecule analysis of the tau proteoform landscape reveals unique disease-associated modifications, a new source of potential biomarkers and drug targets, and a method Nautilus is now extending across disease areas First large-scale, single-molecule analysis of the tau proteoform landscape reveals unique disease-associated modifications, a new source of potential biomarkers and drug targets, and a method Nautilus is now extending across disease areas

Seeking Alpha·Aug 3, 2026
Nautilus Biotechnology: Contrarian Proteoformics Play After The Recent Pullback

NAUT is now prioritizing targeted proteoform assays after Broadscale testing failed to support its prior commercialization roadmap. But their roadmap with Voyager is clearer, although Early Access revenue remains too limited to prove it can turn into recurring sales. Unfortunately, the main risks going forward are still tied to potential execution setbacks, its ongoing cash burn, and a likely capital raise by 2027.

Seeking Alpha·Jul 28, 2026
Nautilus Biotechnology, Inc. (NAUT) Q2 2026 Earnings Call Transcript

Nautilus Biotechnology, Inc. (NAUT) Q2 2026 Earnings Call Transcript

MarketBeat·Jul 28, 2026
Nautilus Biotechnology Q2 Earnings Call Highlights

Nautilus Biotechnology NASDAQ: NAUT said it is shifting a significant share of its research and development resources toward proteoform applications, citing customer interest and a delay in its Broadscale broad-proteome program.

Filtered for Nautilus Biotechnolgy, Inc.More Headlines
04

Compare before deciding

Benchmark NAUT against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Nautilus Biotechnolgy, Inc. (NAUT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
NAUT logoNAUTNautilus Biotechnolgy, Inc.Current
$0.95$121.39M-2.03——-32.27%—
CDNA logoCDNACareDx, Inc
$54.31$2.81B-135.7813.79%24.23%32.81%—
SEER logoSEERSeer, Inc.
$1.80$98.97M-1.4115.57%-490.71%-27.23%—
QBTS logoQBTSD-Wave Quantum Inc.
$16.81$6.17B-15.14178.54%-2001.59%-26.67%—
ILMN logoILMNIllumina, Inc.
$255.38$38.64B46.86-0.78%18.36%31.08%—
PACB logoPACBPacific Biosciences of California, Inc.
$1.41$437.95M-0.773.89%-82.49%-4961.74%—

Compare NAUT vs Peers

Nautilus Biotechnolgy, Inc. (NAUT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CDNA

Most directly comparable listed peer for NAUT.

Scale Benchmark

vs TMO

Larger-name benchmark to compare NAUT against a more recognizable public peer.

Peer Set

Compare Top 5

vs CDNA, SEER, QBTS, ILMN

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

NAUT SEC Filings & Documents

Nautilus Biotechnolgy, Inc. (NAUT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 28, 2026·SEC

Material company update

Jun 18, 2026·SEC

Material company update

Apr 28, 2026·SEC

10-K Annual Reports

5
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 28, 2026·SEC

FY 2026

Apr 28, 2026·SEC

FY 2025

Oct 28, 2025·SEC

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NAUT Frequently Asked Questions

Nautilus Biotechnolgy, Inc. (NAUT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Nautilus Biotechnolgy, Inc.'s revenue?

Nautilus Biotechnolgy, Inc. (NAUT) reported $0.2M in revenue for fiscal year 2025.

Is NAUT profitable?

Nautilus Biotechnolgy, Inc. (NAUT) reported a net loss of $56.5M for fiscal year 2025.

Dividend & Returns
What is NAUT's return on equity?

Nautilus Biotechnolgy, Inc. (NAUT) has a return on equity (ROE) of -32.3%. Negative ROE indicates the company is unprofitable.

What is Nautilus Biotechnolgy, Inc.'s free cash flow?

Nautilus Biotechnolgy, Inc. (NAUT) had negative free cash flow of $51.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in NAUT back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →