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NAUT logoNautilus Biotechnology, Inc.(NAUT)Earnings, Financials & Key Ratios

NAUT•NASDAQ
$2.94
$374M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDiagnostics and Omics Tools
AboutNautilus Biotechnology, Inc., a development stage life sciences company, engages in creating a platform technology for quantifying and unlocking the complexity of the proteome. It develops Nautilus Platform, a proteomics platform that includes end-to-end solution comprised of instruments, consumables, and software analysis. The company was founded in 2016 and is headquartered in Seattle, Washington.Show more
  • Revenue$0
  • EBITDA-$60M+19.6%
  • Net Income-$59M+16.6%
  • EPS (Diluted)-0.47+16.1%
  • ROE-32.27%-8.1%
  • ROIC-25.96%-4.5%
  • Debt/Equity0.19+31.0%
Technical→

NAUT Key Insights

Nautilus Biotechnology, Inc. (NAUT) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 95 (top 5%)

✗Weaknesses

  • ✗Profits declining 30.4% over 5 years
  • ✗Weak Piotroski F-Score: 1/9
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

NAUT Price & Volume

Nautilus Biotechnology, Inc. (NAUT) stock price & volume — 10-year historical chart

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NAUT Growth Metrics

Nautilus Biotechnology, Inc. (NAUT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM16.86%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM14.81%

Return on Capital

10 Years-30.67%
5 Years-25%
3 Years-28.81%
Last Year-31.96%

NAUT Recent Earnings

Nautilus Biotechnology, Inc. (NAUT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 12/12 qtrs (100%)
Q2 2026Latest
Apr 28, 2026
EPS
$0.12
Est $0.14
+17.2%
Revenue
—
Est $250,000
Q1 2026
Feb 26, 2026
EPS
$0.11
Est $0.14
+21.4%
Revenue
—
Est $1M
Q4 2025
Oct 27, 2025
EPS
$0.11
Est $0.15
+26.7%
Revenue
—
Q3 2025
Jul 31, 2025
EPS
$0.12
Est $0.15
+22.6%
Revenue
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 28, 2026
$0.12vs $0.14+17.2%
—vs $250,000
Q1 2026Feb 26, 2026
$0.11vs $0.14+21.4%
—vs $1M
Q4 2025Oct 27, 2025
$0.11vs $0.15+26.7%
—
Q3 2025Jul 31, 2025
$0.12vs $0.15+22.6%
—
Based on last 12 quarters of dataView full earnings history →

NAUT Peer Comparison

Nautilus Biotechnology, Inc. (NAUT) competitors in Diagnostics and Omics Tools — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
CDNA logoCDNACareDx, IncDirect Competitor1.08B20.94-52.3513.79%-1.98%-2.61%0.06
SEER logoSEERSeer, Inc.Direct Competitor105.44M1.89-1.36-8.13%-486.02%-29.19%0.08
QBTS logoQBTSD-Wave Quantum Inc.Direct Competitor8.48B23.84-21.48178.54%-14.44%-41.66%0.01
ILMN logoILMNIllumina, Inc.Product Competitor21.66B142.5826.16-0.78%19.43%32.84%0.94
PACB logoPACBPacific Biosciences of California, Inc.Product Competitor516.17M1.71-1.60-23.19%-325.8%-13.95%1.33
BFLY logoBFLYButterfly Network, Inc.Product Competitor1.19B4.55-14.6818.96%-73.63%-36.79%0.10
TWST logoTWSTTwist Bioscience CorporationProduct Competitor3.71B59.53-45.7920.32%-19.85%-17.46%0.29
BEAM logoBEAMBeam Therapeutics Inc.Product Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24

Compare NAUT vs Peers

Nautilus Biotechnology, Inc. (NAUT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CDNA

Most directly comparable listed peer for NAUT.

Scale Benchmark

vs TMO

Larger-name benchmark to compare NAUT against a more recognizable public peer.

Peer Set

Compare Top 5

vs CDNA, SEER, QBTS, ILMN

NAUT Income Statement

Nautilus Biotechnology, Inc. (NAUT) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue000000000
Revenue Growth %---------
Cost of Goods Sold002.35M2.84M3.42M5.71M6.35M6.46M6.32M
COGS % of Revenue---------
Gross Profit
0▲ 0%
0▲ 0%
-2.35M▲ 0%
-2.84M▼ 21.1%
-3.42M▼ 20.2%
-5.71M▼ 67.0%
-6.35M▼ 11.4%
-6.46M▼ 1.8%
-6.32M▲ 0%
Gross Margin %---------
Gross Profit Growth %----21.14%-20.2%-67.01%-11.36%-1.76%-
Operating Expenses111.68M10.11M13.4M47.66M60.2M70.45M75.12M60.37M59.28M
OpEx % of Revenue---------
Selling, General & Admin111.68M1.62M3.31M21.15M23.75M28.9M31M25.73M22.47M
SG&A % of Revenue---------
Research & Development08.49M10.09M26.51M36.45M47.25M50.48M41.11M39.75M
R&D % of Revenue---------
Other Operating Expenses00000-5.71M-6.35M-6.46M-1000K
Operating Income
-111.68M▲ 0%
-10.11M▲ 90.9%
-15.74M▼ 55.7%
-50.5M▼ 220.7%
-63.62M▼ 26.0%
-76.15M▼ 19.7%
-81.48M▼ 7.0%
-66.84M▲ 18.0%
-64.12M▲ 0%
Operating Margin %---------
Operating Income Growth %-90.95%-55.73%-220.74%-25.98%-19.7%-6.99%17.97%-
EBITDA626.6M-9.56M-13.4M-47.66M-60.2M-74.3M-75.12M-60.37M-57.8M
EBITDA Margin %---------
EBITDA Growth %--101.53%-40.12%-255.69%-26.33%-23.42%-1.1%19.64%14.4%
D&A (Non-Cash Add-back)738.28M548K2.35M2.84M3.42M1.85M6.35M6.46M6.32M
EBIT-111.68M-10.11M-15.62M-50.31M-57.92M-76.15M-70.78M-59M-58.51M
Net Interest Income000329K012.55M10.78M7.87M7.08M
Interest Income000329K5.82M12.55M10.78M7.87M7.08M
Interest Expense00005.82M0000
Other Income/Expense738.28M492K125K183K5.69M12.48M10.7M7.84M7.03M
Pretax Income
626.6M▲ 0%
-9.62M▼ 101.5%
-15.62M▼ 62.4%
-50.31M▼ 222.1%
-57.92M▼ 15.1%
-63.67M▼ 9.9%
-70.78M▼ 11.2%
-59M▲ 16.6%
-57.09M▲ 0%
Pretax Margin %---------
Income Tax000000000
Effective Tax Rate %0%0%0%0%0%0%0%0%0%
Net Income
626.6M▲ 0%
-9.62M▼ 101.5%
-15.62M▼ 62.4%
-50.31M▼ 222.1%
-57.92M▼ 15.1%
-63.67M▼ 9.9%
-70.78M▼ 11.2%
-59M▲ 16.6%
-57.09M▲ 0%
Net Margin %---------
Net Income Growth %--101.53%-62.39%-222.14%-15.12%-9.93%-11.16%16.64%16.86%
Net Income (Continuing)626.6M-9.62M-15.62M-50.31M-57.92M-63.67M-70.78M-59M-57.09M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
87.18▲ 0%
-1.59▼ 101.8%
-0.47▲ 70.4%
-0.60▼ 27.7%
-0.46▲ 23.3%
-0.51▼ 10.9%
-0.56▼ 9.8%
-0.47▲ 16.1%
-0.45▲ 0%
EPS Growth %--101.82%70.44%-27.66%23.33%-10.87%-9.8%16.07%14.81%
EPS (Basic)87.18-1.59-0.47-0.60-0.46-0.51-0.56-0.47-
Diluted Shares Outstanding7.19M6.07M33.07M84.46M124.59M124.92M125.43M126.26M126.63M
Basic Shares Outstanding7.19M6.07M33.07M84.46M124.59M124.92M125.43M126.26M126.63M
Dividend Payout Ratio---------

NAUT Balance Sheet

Nautilus Biotechnology, Inc. (NAUT) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets1.33M16.96M77.66M349.22M187.21M176.84M132.83M105.96M98.83M
Cash & Short-Term Investments144.49B16.66M76.74M345.73M184.47M173.42M129.89M103.41M95.87M
Cash Only1.2M595K36.61M185.62M114.52M19.4M27.65M12.39M14.63M
Short-Term Investments144.49B16.06M40.13M160.11M69.95M154.02M102.25M91.02M81.24M
Accounts Receivable000000000
Days Sales Outstanding---------
Inventory000000000
Days Inventory Outstanding---------
Other Current Assets-144.49B00003.42M2.93M2.56M2.96M
Total Non-Current Assets144.49M1.58M7.35M49.23M162.84M128.73M109.92M85.15M78.95M
Property, Plant & Equipment01.12M6.21M31.86M32.57M36.9M32.33M31.23M30.27M
Fixed Asset Turnover--------0.00x
Goodwill000000000
Intangible Assets000000000
Long-Term Investments144.49M0016.37M129.17M90.65M76.41M52.74M168.94M
Other Non-Current Assets0459K1.14M997K1.11M1.18M1.18M1.18M4.72M
Total Assets
145.82M▲ 0%
18.54M▼ 87.3%
85.01M▲ 358.5%
398.45M▲ 368.7%
350.05M▼ 12.1%
305.56M▼ 12.7%
242.74M▼ 20.6%
191.11M▼ 21.3%
177.78M▲ 0%
Asset Turnover--------0.00x
Asset Growth %--87.28%358.48%368.7%-12.15%-12.71%-20.56%-21.27%-87.66%
Total Current Liabilities5K490K3.02M5.81M6.79M9.12M7.63M7.95M8.34M
Accounts Payable0289K470K1.72M1.27M1.64M987K943K1.19M
Days Payables Outstanding--73.12221.29135.91104.8656.7153.2457.73
Short-Term Debt00000003.83M3.85M
Deferred Revenue (Current)000000000
Other Current Liabilities5K77K617K388K438K2.97M2.55M3.18M3.31M
Current Ratio266.45x34.62x25.73x60.09x27.57x19.39x17.40x13.33x13.33x
Quick Ratio266.45x34.62x25.73x60.09x27.57x19.39x17.40x13.33x13.33x
Cash Conversion Cycle---------
Total Non-Current Liabilities5M275M111.71M29.06M28.34M31.09M26.38M26.19M25.02M
Long-Term Debt5M275M0000026.19M25.02M
Capital Lease Obligations003.3M29.06M28.34M31.09M26.38M046.75M
Deferred Tax Liabilities000000000
Other Non-Current Liabilities00108.42M000000
Total Liabilities140.82M490K114.73M34.87M35.13M40.21M34.01M34.14M33.36M
Total Debt5M275M4.78M30.03M30.33M34.63M30.48M30.02M28.87M
Net Debt3.8M274.4M-31.83M-155.59M-84.19M15.23M2.83M17.63M14.25M
Debt / Equity1.00x15.23x-0.08x0.10x0.13x0.15x0.19x0.19x
Debt / EBITDA0.01x--------0.50x
Net Debt / EBITDA0.01x--------0.25x
Interest Coverage-----9.96x----
Total Equity
5M▲ 0%
18.05M▲ 261.0%
-29.72M▼ 264.6%
363.58M▲ 1323.3%
314.92M▼ 13.4%
265.35M▼ 15.7%
208.73M▼ 21.3%
156.97M▼ 24.8%
144.41M▲ 0%
Equity Growth %-261.04%-264.64%1323.3%-13.38%-15.74%-21.34%-24.8%-97.85%
Book Value per Share0.702.98-0.904.302.532.121.661.241.14
Total Shareholders' Equity5M18.05M-29.72M363.58M314.92M265.35M208.73M156.97M144.41M
Common Stock01K1K12K12K13K13K13K13K
Retained Earnings626.6K-14.71M-30.32M-80.64M-138.56M-202.24M-273.02M-332.02M-346.72M
Treasury Stock000000000
Accumulated OCI07K3K-184K-1.85M-255K57K243K-91K
Minority Interest000000000

NAUT Cash Flow Statement

Nautilus Biotechnology, Inc. (NAUT) cash flow — operating, investing & free cash flow history

Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations-238.3M-9.66M-14M-39.24M-45.81M-51.71M-59.15M-50.7M-50.7M
Operating CF Margin %---------
Operating CF Growth %-95.95%-44.86%-180.37%-16.73%-12.89%-14.38%14.29%49.01%
Net Income626.6M-9.62M-15.62M-50.31M-57.92M-63.67M-70.78M-59M-57.09M
Depreciation & Amortization0548K2.35M2.84M3.42M5.71M6.35M6.46M6.32M
Stock-Based Compensation0110K369K7.93M10.38M12.14M12.7M6.84M6.04M
Deferred Taxes000000000
Other Non-Cash Items-866.23M-157K295K320K-890K-2.66M-1.96M-1.42M-947K
Working Capital Changes1.33M-545K-1.39M-22K-788K-3.22M-5.46M-3.58M-4.18M
Change in Receivables000000000
Change in Inventory000000000
Change in Payables00123K1.26M-561K393K-578K-69K262K
Cash from Investing1.2M4.05M-25.28M-138.96M-25.74M-43.73M66.25M35.22M29.95M
Capital Expenditures0-926K-921K-2.27M-2.32M-2.44M-2.12M-1.28M-1.57M
CapEx % of Revenue---------
Acquisitions000000000
Investments---------
Other Investing1.2M4.98M0000154.65M0-11.13M
Cash from Financing145.19B36K75.9M327.45M562K368K1.14M214K1.3M
Debt Issued (Net)000000000
Equity Issued (Net)0075.86M-7.96M562K368K1.14M214K1.3M
Dividends Paid000000000
Share Repurchases-1.2M-874.33K0000000
Other Financing145.19B36K42K335.41M00000
Net Change in Cash
1.2M▲ 0%
595K▼ 50.3%
36.62M▲ 6055.3%
149.24M▲ 307.5%
-70.98M▼ 147.6%
-95.08M▼ 33.9%
8.25M▲ 108.7%
-15.26M▼ 285.0%
-18.61M▲ 0%
Free Cash Flow
-238.3M▲ 0%
-10.59M▲ 95.6%
-14.92M▼ 40.9%
-41.51M▼ 178.3%
-48.13M▼ 15.9%
-54.15M▼ 12.5%
-61.27M▼ 13.1%
-51.97M▲ 15.2%
-51.43M▲ 0%
FCF Margin %---------
FCF Growth %-95.56%-40.89%-178.27%-15.95%-12.51%-13.14%15.17%12.11%
FCF per Share-33.15-1.75-0.45-0.49-0.39-0.43-0.49-0.41-0.41
FCF Conversion (FCF/Net Income)-0.38x1.00x0.90x0.78x0.79x0.81x0.84x0.86x0.90x
Interest Paid000000000
Taxes Paid000000000

NAUT Key Ratios

Nautilus Biotechnology, Inc. (NAUT) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2019202020212022202320242025TTM
Return on Equity (ROE)-83.45%--30.14%-17.07%-21.95%-29.86%-32.27%-35.04%
Return on Invested Capital (ROIC)-5.03%-10.23%-51.73%-21.75%-22.34%-24.83%-25.96%-25.96%
Debt / Equity15.23x-0.08x0.10x0.13x0.15x0.19x0.19x
Interest Coverage----9.96x----
FCF Conversion1.00x0.90x0.78x0.79x0.81x0.84x0.86x0.90x

NAUT SEC Filings & Documents

Nautilus Biotechnology, Inc. (NAUT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 28, 2026·SEC

Material company update

Nov 4, 2025·SEC

Material company update

Oct 28, 2025·SEC

10-K Annual Reports

5
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Apr 28, 2026·SEC

FY 2025

Oct 28, 2025·SEC

FY 2025

Jul 31, 2025·SEC

NAUT Frequently Asked Questions

Nautilus Biotechnology, Inc. (NAUT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Nautilus Biotechnology, Inc. (NAUT) grew revenue by 0.0% over the past year. Growth has been modest.

Nautilus Biotechnology, Inc. (NAUT) reported a net loss of $57.1M for fiscal year 2025.

Dividend & Returns

Nautilus Biotechnology, Inc. (NAUT) has a return on equity (ROE) of -32.3%. Negative ROE indicates the company is unprofitable.

Nautilus Biotechnology, Inc. (NAUT) had negative free cash flow of $51.4M in fiscal year 2025, likely due to heavy capital investments.

Explore More NAUT

Nautilus Biotechnology, Inc. (NAUT) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

→

Valuation

DCF intrinsic value, peer multiples & estimates

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