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NAUTNautilus Biotechnolgy, Inc.
$2.23$284M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
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NAUT logo

Nautilus Biotechnolgy, Inc.

NAUT
NASDAQ · Life Science Tools
$2.23
At close - Nov 6, 4:00 PM EST - USD
Market Cap$284M
P/E-4.8x
52W High$4.31
Volume4.54M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Sub-Scale Revenue Meets Structural Cash Burn At Nautilus

Nautilus Biotechnology's first commercial revenue of $234K in 2026Q3 represents a milestone, but it offsets less than 1% of the roughly $17M quarterly operating cost base, leaving cash burn structurally intact at approximately $14.7M of free cash outflow in the quarter.

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsNeutral
Explore valuation models
MARKET ACTION

NAUT price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

12/12 Beats

EPS beat 12 of last 12 quarters

02

Valuation risk

-113% Peers

P/E is 113% below peer median

03

Market leadership

RS 97 · Leader

High momentum (Outperforming 97% of market)

04

Trend Check

N/A

Trend data unavailable

Next CatalystEstimated earnings · Jan 27

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
NAUT+16.75%
S&P 500 (^GSPC)+7.63%
1-Year Return
NAUT+47.68%
S&P 500 (^GSPC)+9.69%
3-Year Return
NAUT-8.98%
S&P 500 (^GSPC)+73.80%
5-Year Return
NAUT-60.04%
S&P 500 (^GSPC)+61.19%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$59M+16.6% YoY
Free cash flow FY25
-$52M+15.2% YoY
Operating margin FY25
-
ROIC (FY25)-26%
Avg ROIC 5Y-29.3%
ROE (TTM)-42.7%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate12/12 (100%)
Revenue Beat Rate2/12 (100%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Oct 27, 2026
-$0.12+14.3%
vs -$0.14
$234,000+13.5%
vs $206,250
Q3 2026
Jul 28, 2026
-$0.11+18.5%
vs -$0.14
$190,000+90.0%
vs $100,000
Q2 2026
Apr 28, 2026
-$0.12+17.2%
vs -$0.14
—
vs $250,000
Q1 2026
Feb 26, 2026
-$0.11+21.4%
vs -$0.14
—
vs $1M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Seeking Alpha·Oct 29, 2026
Nautilus Biotechnology: Bullish On Voyager's Upcoming Launch

NAUT is extending Voyager from tau into oncology, which I think will give it more applications for its targeted proteoform platform. NAUT also has research collaborations and SEEDS participation. In my view, this corroborates that there's real scientific interest in their platform. Management's runway projection should be enough to reach their planned launch of Voyager instruments and initial assay kits.

Seeking Alpha·Oct 27, 2026
Nautilus Biotechnology, Inc. (NAUT) Q3 2026 Earnings Call Transcript

Nautilus Biotechnology, Inc. (NAUT) Q3 2026 Earnings Call Transcript

MarketBeat·Oct 27, 2026
Nautilus Biotechnology Q3 Earnings Call Highlights

Nautilus Biotechnology NASDAQ: NAUT reported third-quarter revenue of $200,000 as it continued its transition toward commercialization of its Voyager proteomics platform, with management reaffirming plans to begin taking platform pre-orders in early 2027 and start instrument shipments in mid-2027.

GlobeNewsWire·Oct 27, 2026
Nautilus to Measure Proteoforms Driving Alzheimer's Disease and Cancer in ARPA-H-Funded SEEDS Consortium

Nautilus expects to receive up to $6 million to bring its Voyager™ Platform to a multidisciplinary team integrating protein science, AI, and computational modeling to develop new diagnostics and therapeutics Nautilus expects to receive up to $6 million to bring its Voyager™ Platform to a multidisciplinary team integrating protein science, AI, and computational modeling to develop new diagnostics and therapeutics

Filtered for Nautilus Biotechnolgy, Inc.More Headlines
04

Compare before deciding

Benchmark NAUT against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Nautilus Biotechnolgy, Inc. (NAUT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
NAUT logoNAUTNautilus Biotechnolgy, Inc.Current
$2.23$283.78M-4.84—-13816.75%-42.68%—
CDNA logoCDNACareDx, Inc
$78.56$4.06B33.5813.79%25.86%34.08%—
SEER logoSEERSeer, Inc.
$1.63$89.62M-1.3215.57%-490.71%-27.23%—
QBTS logoQBTSD-Wave Quantum Inc.
$10.68$3.92B-15.93178.54%-2001.59%-26.67%—
ILMN logoILMNIllumina, Inc.
$213.13$32.25B36.67-0.78%19.72%31.45%—
PACB logoPACBPacific Biosciences of California, Inc.
$2.26$701.96M-5.363.89%-81.31%-2618.51%—

Compare NAUT vs Peers

Nautilus Biotechnolgy, Inc. (NAUT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CDNA

Most directly comparable listed peer for NAUT.

Scale Benchmark

vs TMO

Larger-name benchmark to compare NAUT against a more recognizable public peer.

Peer Set

Compare Top 5

vs CDNA, SEER, QBTS, ILMN

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

NAUT SEC Filings & Documents

Nautilus Biotechnolgy, Inc. (NAUT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Oct 27, 2026·SEC

Material company update

Jul 28, 2026·SEC

Material company update

Jun 18, 2026·SEC

10-K Annual Reports

4
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Oct 27, 2026·SEC

FY 2026

Jul 28, 2026·SEC

FY 2026

Apr 28, 2026·SEC

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NAUT Frequently Asked Questions

Nautilus Biotechnolgy, Inc. (NAUT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Nautilus Biotechnolgy, Inc.'s revenue?

Nautilus Biotechnolgy, Inc. (NAUT) reported $0.4M in revenue over the trailing twelve months.

Is NAUT profitable?

No. Nautilus Biotechnolgy, Inc. (NAUT) reported a net loss of $58.6M over the trailing twelve months.

Dividend & Returns
What is NAUT's return on equity?

Nautilus Biotechnolgy, Inc. (NAUT) had a return on equity (ROE) of -42.7% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Nautilus Biotechnolgy, Inc.'s free cash flow?

Nautilus Biotechnolgy, Inc. (NAUT) had negative free cash flow of $55.1M over the trailing twelve months.

What if you invested $1,000 in NAUT back in 2018?

Total return calculator · dividends reinvested · 8+ years of data

See returns →