← Back to Screener
US Stock Screener
HomeScreensNewsWatchlist
...

Prime Medicine, Inc. (PRME) 10-Year Financial Performance & Capital Metrics

PRME •
HealthcareBiotechnologyRNA and Genome Editing Developers
AboutPrime Medicine, Inc., a biotechnology company, delivers genetic therapies to address diseases by deploying gene editing technology. It offers Prime Editors with a Prime Editor protein, comprising a fusion between a Cas protein and a reverse transcriptase enzyme; and a pegRNA, which targets the Prime Editor to a specific genomic location and provides a template for making the desired edit to the target DNA sequence. The company was incorporated in 2019 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue $3M
  • EBITDA -$196M +1.9%
  • Net Income -$196M +1.1%
  • EPS (Diluted) -1.65 +24.2%
  • Gross Margin 100%
  • EBITDA Margin -6581.93%
  • Operating Margin -6787.36%
  • Net Margin -6566.61%
  • ROE -136.88% -55.2%
  • ROIC -260.47% -122.6%
  • Debt/Equity 0.27 +160.0%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 87 (top 13%)

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 30.4% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

Loading chart...

Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM647.13%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM9.99%

EPS CAGR

10Y-
5Y-
3Y-
TTM26.54%

ROCE

10Y Avg-75.21%
5Y Avg-58.98%
3Y Avg-76.44%
Latest-102%

Peer Comparison

RNA and Genome Editing Developers
Select Columns
Size & Scale
Valuation
Per Share
Growth
Profitability
Quality & Returns
Safety & Leverage
TTM Growth
Famous Investor Metrics
Dividends
Latest Quarter
Momentum & Returns
Total Return (DRIP)
Technical
Volume & Trading
Shares & Dilution
Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
ALNYAlnylam Pharmaceuticals, Inc.44.07B332.92142.8865.19%8.45%39.76%1.06%3.76
SLXNWSilexion Therapeutics Ltd.63.6M0.030.00-132.54%
EDITEditas Medicine, Inc.205.18M2.20-0.76-58.64%-430.84%-14.85%0.26
SGMOSangamo Therapeutics, Inc.92.01M0.43-0.88-67.2%-331.28%-17.44%1.34
CAMPCAMP4 Therapeutics Corporation210.49M4.49-1.6986.29%-14.04%-133.54%0.14
SLNSilence Therapeutics plc256.95M5.44-1.7170.47%-252.16%-84.61%0.00
PEPGPepGen Inc.202.89M6.22-2.18-57.35%0.16
ARCTArcturus Therapeutics Holdings Inc.224.14M8.23-2.74-12.27%-72.48%-29.71%0.12

Compare PRME vs Peers

Analyze head-to-head performance against top industry competitors across valuation, growth, and profitability metrics.

vs ALNY

Compare head-to-head with Alnylam Pharmaceuticals, Inc.

vs IONS

Compare head-to-head with Ionis Pharmaceuticals, Inc.

Compare Top 5

vs ALNY, IONS, ARWR, CRSP

Profit & Loss

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+05.21M0002.98M
Revenue Growth %---100%---
Cost of Goods Sold+2.76M2.98M0000
COGS % of Revenue-57.2%----
Gross Profit+-2.76M2.23M0002.98M
Gross Margin %-42.8%---100%
Gross Profit Growth %-180.8%-100%---
Operating Expenses+2.17M3.16M84.47M116.54M204.79M205.45M
OpEx % of Revenue-60.69%---6887.36%
Selling, General & Admin1.25M3.16M13.92M29.82M43.39M50.16M
SG&A % of Revenue-60.69%---1681.56%
Research & Development920K2.98M70.55M86.72M147.91M155.29M
R&D % of Revenue-57.2%---5205.8%
Other Operating Expenses0-2.98M0013.5M0
Operating Income+-2.17M-932K-84.47M-116.54M-204.79M-202.47M
Operating Margin %--17.89%----6787.36%
Operating Income Growth %-57.09%-8963.73%-37.96%-75.72%1.14%
EBITDA+4.34M-889K-83.91M-114.32M-200.14M-196.34M
EBITDA Margin %--17.06%----6581.93%
EBITDA Growth %--120.47%-9338.25%-36.25%-75.07%1.9%
D&A (Non-Cash Add-back)6.52M43K568K2.22M4.65M6.13M
EBIT-2.52M-932K-84.47M-116.54M-191.29M-202.47M
Net Interest Income+000003.52M
Interest Income000003.52M
Interest Expense000000
Other Income/Expense0-611K-81.38M-6.22M6.38M6.58M
Pretax Income+-2.52M-1.54M-165.85M-122.77M-198.41M-195.88M
Pretax Margin %--29.62%----6566.61%
Income Tax+4K1.87M-486K-948K-279K0
Effective Tax Rate %100.16%221%99.71%99.23%99.86%100%
Net Income+-2.53M-3.41M-165.37M-121.82M-198.13M-195.88M
Net Margin %--65.45%----6566.61%
Net Income Growth %--34.84%-4749.47%26.33%-62.64%1.14%
Net Income (Continuing)-2.53M-3.41M-165.37M-121.82M-198.13M-195.88M
Discontinued Operations000000
Minority Interest000000
EPS (Diluted)+-0.03-0.05-1.92-1.46-2.18-1.65
EPS Growth %--80.82%-3542.61%24.04%-49.09%24.17%
EPS (Basic)-0.03-0.05-1.92-1.46-2.18-1.65
Diluted Shares Outstanding95.73M95.73M95.73M97.21M90.97M118.6M
Basic Shares Outstanding95.73M95.73M95.73M97.21M90.97M118.6M
Dividend Payout Ratio------

Balance Sheet

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+8.7M53.4M270.58M296.62M142.98M211.89M
Cash & Short-Term Investments8.65M53.33M269.62M293.92M121.67M190.44M
Cash Only8.65M36.98M185.42M187.62M41.57M182.48M
Short-Term Investments016.35M84.2M106.3M80.09M7.97M
Accounts Receivable000000
Days Sales Outstanding------
Inventory000000
Days Inventory Outstanding------
Other Current Assets50K00246K2.25M14.67M
Total Non-Current Assets+01.38M31.28M63.7M50.88M85.62M
Property, Plant & Equipment0596K15.68M48.55M36.6M71.56M
Fixed Asset Turnover-8.74x---0.04x
Goodwill000000
Intangible Assets000000
Long-Term Investments000000
Other Non-Current Assets0785K15.6M15.14M14.28M14.06M
Total Assets+8.7M54.78M301.86M360.31M193.85M297.51M
Asset Turnover-0.10x---0.01x
Asset Growth %-529.91%451%19.37%-46.2%53.47%
Total Current Liabilities+7.31M19.44M57.98M26.71M56.42M37.96M
Accounts Payable0250K1.44M4.33M19.54M11.35M
Days Payables Outstanding-30.62----
Short-Term Debt000000
Deferred Revenue (Current)000007.09M
Other Current Liabilities7.31M19.08M14.66M6.98M10.91M6.93M
Current Ratio1.19x2.75x4.67x11.10x2.53x5.58x
Quick Ratio1.19x2.75x4.67x11.10x2.53x5.58x
Cash Conversion Cycle------
Total Non-Current Liabilities+01.87M4.31M17.33M4.36M106.4M
Long-Term Debt000000
Capital Lease Obligations003.07M17.05M4.36M37.18M
Deferred Tax Liabilities01.87M1.24M279K00
Other Non-Current Liabilities000006M
Total Liabilities7.31M21.31M62.3M44.04M60.78M144.36M
Total Debt+0010.41M28.75M13.63M40.79M
Net Debt-8.65M-36.98M-175.01M-158.88M-27.94M-141.68M
Debt / Equity--0.04x0.09x0.10x0.27x
Debt / EBITDA------
Net Debt / EBITDA-1.99x-----
Interest Coverage------
Total Equity+1.39M33.47M239.56M316.27M133.07M153.15M
Equity Growth %-2309.94%615.66%32.02%-57.92%15.09%
Book Value per Share0.010.352.503.251.461.29
Total Shareholders' Equity1.39M33.47M239.56M316.27M133.07M153.15M
Common Stock1K002K2K2K
Retained Earnings-2.6M-6.01M-171.38M-293.2M-491.33M-687.21M
Treasury Stock000000
Accumulated OCI00-27K-384K-15K1K
Minority Interest000000

Cash Flow

Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-1.33M-5.54M-34.08M-131.83M-165.41M-122.86M
Operating CF Margin %--106.41%----4118.84%
Operating CF Growth %--315.59%-514.75%-286.79%-25.48%25.72%
Net Income-2.53M-3.41M-165.37M-121.82M-198.13M-195.88M
Depreciation & Amortization043K568K2.22M4.65M6.13M
Stock-Based Compensation0391K1.75M6.46M13.91M26.07M
Deferred Taxes01.87M-624K-964K-279K0
Other Non-Cash Items703K-4.6M98.42M17.68M11.79M9.74M
Working Capital Changes492K164K31.18M-35.4M2.65M31.08M
Change in Receivables000000
Change in Inventory000000
Change in Payables0250K1.19M2.46M9.14M-5.26M
Cash from Investing+0-1.06M-73.63M-47.1M18.71M68.46M
Capital Expenditures0-639K-4.15M-16.09M-8.72M-7.29M
CapEx % of Revenue-12.26%---244.52%
Acquisitions000000
Investments------
Other Investing0-423K-496K-665K-170K1M
Cash from Financing+9.98M34.93M269.28M181.49M655K195.88M
Debt Issued (Net)000000
Equity Issued (Net)1000K1000K1000K1000K655K1000K
Dividends Paid000000
Share Repurchases000000
Other Financing0-20K-1.09M-3.82M025.74M
Net Change in Cash028.33M161.57M2.57M-146.05M141.47M
Free Cash Flow+-1.33M-6.18M-38.23M-147.92M-174.14M-130.16M
FCF Margin %--118.68%----4363.36%
FCF Growth %--363.49%-518.34%-286.91%-17.72%25.25%
FCF per Share-0.01-0.06-0.40-1.52-1.91-1.10
FCF Conversion (FCF/Net Income)0.53x1.63x0.21x1.08x0.83x0.63x
Interest Paid000000
Taxes Paid000141K00

Key Ratios

Metric201920202021202220232024
Return on Equity (ROE)-182.07%-19.56%-121.13%-43.83%-88.19%-136.88%
Return on Invested Capital (ROIC)---207.57%-78.77%-117.01%-260.47%
Gross Margin-42.8%---100%
Net Margin--65.45%----6566.61%
Debt / Equity--0.04x0.09x0.10x0.27x
FCF Conversion0.53x1.63x0.21x1.08x0.83x0.63x
Revenue Growth---100%---

Deep Dive Analysis

Explore detailed financial history, valuation models, and returns analysis

Valuation Overview

DCF models, peer multiples & analyst estimates

Total Return Calculator

Historical returns with dividends reinvested

Dividend History

Yield, growth, payout safety & DRIP calculator

Earnings History

EPS trends, net income & profitability analysis

Price History

Long-term charts & historical price data

Revenue History

Sales growth patterns & revenue breakdown

Financial Ratios

30 years of valuation, profitability & efficiency metrics

VCP Scanner

Find stocks. Verify deeply. Act with conviction.

Patterns find ideas. Fundamentals build conviction.

Data updated daily

Quick Links

  • Home
  • Screens
  • Valuation
  • Compare
  • Total Return
  • News
  • Insights
  • Methodology
  • How It Works
  • Profile

Popular Screens

  • VCP Hot
  • VCP Warm
  • Value Screens
  • Growth Screens
  • Momentum Screens
  • Technical Screens
  • Quality Screens

Community

  • Twitter
  • Get Early Access
© 2026 VCP Scanner. All rights reserved.
Made with ❤️ for investors
Not financial advice. Do your own research.