Prime Medicine, Inc. (PRME) Stock Price History
Historical prices from 2022 to 2026
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PRME Historical Performance
Short-Term Returns
PRME Stock Price Trajectory (2022–2026)
As of May 8, 2026, Prime Medicine, Inc. (PRME) trades at $3.12, representing a +119.4% return over the past year. The stock has delivered a -79.7% total return over five years (-27.3% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $21.73 on November 14, 2022. From this peak, PRME has corrected -85.7%, currently trading 23% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers BEAM (+93.9% 1Y), CRSP (+53.1% 1Y), and EDIT (+127.8% 1Y), PRME has underperformed the peer group average. Compare PRME vs BEAM →
PRME Historical Price Data (2025–2026)
Showing 30 of 890 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-07 | 3.41 | 3.55 | 3.06 | 3.12 | 3.94M | -8.65% |
| 2026-05-06 | 3.46 | 3.48 | 3.28 | 3.41 | 2.69M | +0.59% |
| 2026-05-05 | 3.49 | 3.55 | 3.28 | 3.39 | 2.65M | -2.02% |
| 2026-05-04 | 3.40 | 3.58 | 3.37 | 3.46 | 1.10M | +1.47% |
| 2026-05-01 | 3.52 | 3.53 | 3.35 | 3.41 | 1.78M | -3.81% |
| 2026-04-30 | 3.54 | 3.69 | 3.50 | 3.54 | 1.55M | +0.42% |
| 2026-04-29 | 3.63 | 3.69 | 3.51 | 3.53 | 1.41M | -4.34% |
| 2026-04-28 | 3.64 | 3.79 | 3.62 | 3.69 | 1.57M | +0.54% |
| 2026-04-27 | 3.73 | 3.98 | 3.64 | 3.67 | 1.48M | -0.81% |
| 2026-04-24 | 3.82 | 3.85 | 3.66 | 3.70 | 1.45M | -3.65% |
| 2026-04-23 | 3.97 | 4.03 | 3.78 | 3.84 | 1.84M | -3.03% |
| 2026-04-22 | 3.82 | 3.97 | 3.81 | 3.96 | 1.76M | +3.94% |
| 2026-04-21 | 3.89 | 3.96 | 3.75 | 3.81 | 2.11M | -2.06% |
| 2026-04-20 | 3.77 | 3.92 | 3.69 | 3.89 | 1.04M | +2.10% |
| 2026-04-17 | 3.78 | 3.91 | 3.76 | 3.81 | 1.88M | +3.81% |
| 2026-04-16 | 3.79 | 3.79 | 3.61 | 3.67 | 1.51M | -3.17% |
| 2026-04-15 | 3.76 | 3.84 | 3.65 | 3.79 | 2.17M | +2.43% |
| 2026-04-14 | 3.76 | 3.87 | 3.65 | 3.70 | 2.44M | +1.09% |
| 2026-04-13 | 3.38 | 3.73 | 3.36 | 3.66 | 1.80M | +6.71% |
| 2026-04-10 | 3.50 | 3.54 | 3.27 | 3.43 | 1.68M | -2.28% |
| 2026-04-09 | 3.50 | 3.55 | 3.45 | 3.51 | 1.27M | -0.85% |
| 2026-04-08 | 3.69 | 3.71 | 3.44 | 3.54 | 1.71M | +3.81% |
| 2026-04-07 | 3.32 | 3.42 | 3.19 | 3.41 | 1.48M | +2.10% |
| 2026-04-06 | 3.30 | 3.50 | 3.29 | 3.34 | 2.14M | +0.60% |
| 2026-04-02 | 3.27 | 3.45 | 3.23 | 3.32 | 1.63M | -2.06% |
| 2026-04-01 | 3.55 | 3.73 | 3.38 | 3.39 | 2.19M | -2.59% |
| 2026-03-31 | 3.23 | 3.51 | 3.23 | 3.48 | 2.03M | +10.48% |
| 2026-03-30 | 3.33 | 3.42 | 3.05 | 3.15 | 3.91M | -6.80% |
| 2026-03-27 | 3.57 | 3.64 | 3.29 | 3.38 | 4.06M | -7.14% |
| 2026-03-26 | 3.56 | 3.83 | 3.56 | 3.64 | 1.80M | +0.28% |
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Start ComparisonPRME — Frequently Asked Questions
Quick answers to the most common questions about buying PRME stock.
How has PRME stock performed recently?
PRME returned +119.4% over the past year, beating its 5-year annualized CAGR of -27.3%. The stock trades below its 200-day moving average, confirming the uptrend.
What is PRME's all-time high price?
Prime Medicine, Inc. reached $21.73 on 2022-11-14. The 52-week high is $6.94. Current 1-year return of +119.4% places the stock closer to historical peaks.
Where can I download PRME historical price data?
This page provides PRME daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2022-2026, downloadable in CSV format.