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Zymeworks Inc. (ZYME) 10-Year Financial Performance & Capital Metrics

ZYME • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsSolid Tumor Oncology
AboutZymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a novel bispecific antibody that is in Phase 1 and Phase 2 clinical trials for the treatment of biliary tract, gastroesophageal adenocarcinomas, breast, and colorectal cancer; and ZW49, a biparatopic anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate that is in Phase 1 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. The company has strategic partnerships with Merck Sharp & Dohme Research Ltd.; Eli Lilly and Company; Bristol-Myers Squibb company; GlaxoSmithKline Intellectual Property Development Ltd.; Daiichi Sankyo Co., Ltd.; Janssen Biotech, Inc.; BeiGene, Ltd.; and Exelixis, Inc. It also has licensing and research collaboration with LEO Pharma A/S to research, develop, and commercialize bispecific antibodies; and Iconic Therapeutics, Inc. Zymeworks Inc. was incorporated in 2003 and is headquartered in Vancouver, Canada.Show more
  • Revenue $76M +0.4%
  • EBITDA -$126M -4.3%
  • Net Income -$123M -3.4%
  • EPS (Diluted) -1.62 +5.8%
  • Gross Margin 100% +213.5%
  • EBITDA Margin -165.02% -3.9%
  • Operating Margin -179.69% +1.1%
  • Net Margin -160.8% -3.0%
  • ROE -30.54% -23.2%
  • ROIC -32.9% +27.9%
  • Debt/Equity 0.05 -5.0%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 89 (top 11%)
  • ✓Strong 5Y sales CAGR of 20.9%

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 10.2% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y46.55%
5Y20.9%
3Y41.95%
TTM116.21%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM44.2%

EPS CAGR

10Y-
5Y-
3Y-
TTM44%

ROCE

10Y Avg-37.04%
5Y Avg-26.57%
3Y Avg-8.7%
Latest-30.47%

Peer Comparison

Solid Tumor Oncology
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Size & Scale
Valuation
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Quality & Returns
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Total Return (DRIP)
Technical
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
TLXTelix Pharmaceuticals Limited2.49B7.4353.0755.85%3.98%15.63%0.36%1.02
EXELExelixis, Inc.12.18B45.4425.8218.49%29.63%31.37%5.2%0.09
BBOTBridgeBio Oncology Therapeutics Inc.919.87M11.5025-25.73%
INBXInhibrx Biosciences, Inc.1.04B71.800.62-88.89%-110.78%-421.09%0.06
NUVBNuvation Bio Inc.2.1B6.14-2.91-8.13%-66.74%0.02
RLAYRelay Therapeutics, Inc.1.32B7.63-3.23-60.83%-26.71%-48.97%0.06
ORICORIC Pharmaceuticals, Inc.1.12B11.52-6.30-33.24%0.01
ZLABZai Lab Limited2.09B18.82-7.2449.59%-46.83%-27.21%0.18

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+9.66M11.01M51.76M53.02M29.54M38.95M26.68M412.48M76.01M76.3M
Revenue Growth %4.78%0.14%3.7%0.02%-0.44%0.32%-0.32%14.46%-0.82%0%
Cost of Goods Sold+24.4M35.55M41.14M56.93M117.1M170.9M00142.99M0
COGS % of Revenue2.53%3.23%0.79%1.07%3.96%4.39%--1.88%-
Gross Profit+-14.74M-24.54M10.62M-3.91M-87.55M-131.94M26.68M412.48M-66.98M76.3M
Gross Margin %-1.53%-2.23%0.21%-0.07%-2.96%-3.39%1%1%-0.88%1%
Gross Profit Growth %-0.67%-0.66%1.43%-1.37%-21.41%-0.51%1.2%14.46%-1.16%2.14%
Operating Expenses+29.62M48.1M59.22M86.15M63.75M55.52M242.31M281.95M71.08M213.41M
OpEx % of Revenue3.07%4.37%1.14%1.62%2.16%1.43%9.08%0.68%0.94%2.8%
Selling, General & Admin5.22M12.55M18.55M29.46M62.88M55.17M42.6M73.4M70.4M61.5M
SG&A % of Revenue0.54%1.14%0.36%0.56%2.13%1.42%1.6%0.18%0.93%0.81%
Research & Development24.65M36.82M41.75M56.68M118.25M171.34M199.75M208.6M143.62M134.62M
R&D % of Revenue2.55%3.34%0.81%1.07%4%4.4%7.49%0.51%1.89%1.76%
Other Operating Expenses-251K-1.26M-964K-1.26M-117.37M-171M-39K-42K-142.94M17.29M
Operating Income+-19.96M-37.86M-9M-33.13M-151.3M-187.47M-215.63M130.53M-138.05M-137.11M
Operating Margin %-2.07%-3.44%-0.17%-0.62%-5.12%-4.81%-8.08%0.32%-1.82%-1.8%
Operating Income Growth %-0.57%-0.9%0.76%-2.68%-3.57%-0.24%-0.15%1.61%-2.06%0.01%
EBITDA+-19.47M-36.84M-6.26M-29.5M-148.99M-184.11M-206.05M142.53M-120.75M-125.92M
EBITDA Margin %-2.02%-3.35%-0.12%-0.56%-5.04%-4.73%-7.72%0.35%-1.59%-1.65%
EBITDA Growth %-0.58%-0.89%0.83%-3.71%-4.05%-0.24%-0.12%1.69%-1.85%-0.04%
D&A (Non-Cash Add-back)494K1.02M2.74M3.63M2.31M3.35M9.58M12M17.3M11.19M
EBIT-19.12M-37.93M-7.93M-33.36M-150.43M-187.12M-215.67M130.49M-138.01M-119.82M
Net Interest Income+306K-642K-397K2.47M5.88M5.7M1.97M3.6M19.7M19.94M
Interest Income324K308K743K2.64M5.88M5.7M1.97M3.6M19.7M19.94M
Interest Expense18K950K1.14M166K000000
Other Income/Expense824K-1.02M-964K-1.02M6.45M7.34M3.27M4.71M18.81M20.5M
Pretax Income+-19.14M-38.88M-9.96M-34.38M-144.85M-180.12M-212.36M135.23M-119.24M-116.61M
Pretax Margin %-1.98%-3.53%-0.19%-0.65%-4.9%-4.62%-7.96%0.33%-1.57%-1.53%
Income Tax+34K-5.08M444K2.17M582K429K-516K10.89M-568K6.08M
Effective Tax Rate %1%0.87%1.04%1.06%1%1%1%0.92%1%1.05%
Net Income+-19.17M-33.81M-10.41M-36.56M-145.44M-180.55M-211.84M124.34M-118.67M-122.69M
Net Margin %-1.98%-3.07%-0.2%-0.69%-4.92%-4.64%-7.94%0.3%-1.56%-1.61%
Net Income Growth %-0.48%-0.76%0.69%-2.51%-2.98%-0.24%-0.17%1.59%-1.95%-0.03%
Net Income (Continuing)-19.17M-33.81M-10.41M-36.56M-145.44M-180.55M-211.84M124.34M-118.67M-122.69M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-0.97-1.72-0.49-1.26-3.83-3.58-4.061.90-1.72-1.62
EPS Growth %-0.49%-0.77%0.72%-1.57%-2.04%0.07%-0.13%1.47%-1.91%0.06%
EPS (Basic)-0.97-1.72-0.49-1.26-3.83-3.58-4.061.91-1.72-1.62
Diluted Shares Outstanding19.84M19.7M21.32M29.09M38.02M50.38M52.13M65.25M68.86M75.88M
Basic Shares Outstanding19.84M19.7M21.25M29.01M37.97M50.38M52.13M65.19M68.86M75.85M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+17.68M46.48M92.33M204.37M311.83M455.08M288.22M544.71M412.93M300.45M
Cash & Short-Term Investments15.16M40.26M87.8M200.16M298.9M426.35M252.61M492.23M374.33M225.78M
Cash Only11.52M16.44M35.95M42.2M128.45M242.04M201.87M400.91M157.56M66.1M
Short-Term Investments3.64M23.82M51.85M157.96M170.45M184.32M50.74M91.32M216.77M159.67M
Accounts Receivable2.27M4.31M2.33M358K2.19M15.29M15.61M33.4M19.48M55.81M
Days Sales Outstanding85.58142.816.432.4626.99143.31213.6129.5693.53266.99
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets000000019.07M19.12M18.86M
Total Non-Current Assets+5.47M47.51M39.62M39.99M56.38M83.3M100.91M104.02M167.95M162.64M
Property, Plant & Equipment781K6.72M7.18M6.48M16.5M17.61M49.77M47.65M37.54M34.32M
Fixed Asset Turnover12.37x1.64x7.21x8.18x1.79x2.21x0.54x8.66x2.02x2.22x
Goodwill012.02M12.02M12.02M12.02M12.02M12.02M12.02M12.02M12.02M
Intangible Assets144K20.63M19.14M20.01M23.68M22.93M21.47M26.38M25.28M4.58M
Long-Term Investments4.18M000025.92M886K886K81.93M98.43M
Other Non-Current Assets360K3.04M1.22M1.4M2.96M3.1M13.7M15.74M7.57M8.92M
Total Assets+23.15M94M131.96M244.36M368.2M538.38M389.13M648.73M580.88M463.09M
Asset Turnover0.42x0.12x0.39x0.22x0.08x0.07x0.07x0.64x0.13x0.16x
Asset Growth %-0.54%3.06%0.4%0.85%0.51%0.46%-0.28%0.67%-0.1%-0.2%
Total Current Liabilities+4.85M16.56M14.66M29.99M82.55M85.67M71.85M95.63M55.76M88.29M
Accounts Payable2.11M2.96M1.66M2.6M5.35M6.24M5.17M7.86M6.21M3.9M
Days Payables Outstanding31.5930.3414.7616.6616.6713.34--15.86-
Short-Term Debt0000000000
Deferred Revenue (Current)1000K1000K1000K1000K0001000K1000K1000K
Other Current Liabilities48K5.69M2.04M20.63M50.59M48.74M11.1M16.01M8.68M7.49M
Current Ratio3.64x2.81x6.30x6.82x3.78x5.31x4.01x5.70x7.41x3.40x
Quick Ratio3.64x2.81x6.30x6.82x3.78x5.31x4.01x5.70x7.41x3.40x
Cash Conversion Cycle----------
Total Non-Current Liabilities+59K68.44M866K33.89M39.97M42.79M68.19M60.14M60.31M36.03M
Long-Term Debt04.42M00000000
Capital Lease Obligations049K52K42K5.64M5.93M31.02M24.79M22.46M15.77M
Deferred Tax Liabilities16K5.02M0114K408K1.18M1.57M1.79M3.3M4.76M
Other Non-Current Liabilities43K58.95M814K904K978K2.73M2.65M2.98M1.61M895K
Total Liabilities4.91M84.99M15.53M63.87M122.52M128.45M140.04M155.77M116.07M124.32M
Total Debt+6K4.42M62K57K6.93M8.64M32.33M28.11M26.72M18.51M
Net Debt-11.51M-12.01M-35.88M-42.15M-121.52M-233.39M-169.53M-372.8M-130.84M-47.6M
Debt / Equity0.00x0.49x0.00x-0.03x0.02x0.13x0.06x0.06x0.05x
Debt / EBITDA-------0.20x--
Net Debt / EBITDA--------2.62x--
Interest Coverage-1108.89x-39.86x-7.89x-199.56x------
Total Equity+18.24M9M116.43M-145.27M245.68M409.92M249.09M492.96M464.81M338.77M
Equity Growth %-0.54%-0.51%11.93%-2.25%2.69%0.67%-0.39%0.98%-0.06%-0.27%
Book Value per Share0.920.465.46-4.996.468.144.787.556.754.46
Total Shareholders' Equity18.24M9M116.43M-145.27M245.68M409.92M249.09M492.96M464.81M338.77M
Common Stock83.61M106.59M222.99M320.07M450.21M724.22M741.15M906.76M1.01B1.02B
Retained Earnings-63.92M-97.79M-108.72M-145.27M-290.71M-471.26M-683.1M-558.76M-677.44M-830.34M
Treasury Stock0-6.86M00000000
Accumulated OCI-6.66M-6.66M-6.66M-6.66M-6.66M-6.66M-6.66M-6.66M-6.6M-6.95M
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-22.17M-35.25M219K24.18M-81.85M-151.4M-192.45M144.11M-118.3M-110.04M
Operating CF Margin %-2.3%-3.2%0%0.46%-2.77%-3.89%-7.21%0.35%-1.56%-1.44%
Operating CF Growth %-2.16%-0.59%1.01%109.4%-4.39%-0.85%-0.27%1.75%-1.82%0.07%
Net Income-19.17M-33.81M-10.41M-36.56M-145.44M-180.55M-211.84M124.34M-118.67M-122.69M
Depreciation & Amortization494K1.02M2.74M3.63M7.33M10.28M9.58M12M17.3M11.19M
Stock-Based Compensation1.39M4.29M3.43M13.44M49M29.12M10.76M4.01M8.1M17.79M
Deferred Taxes16K-5.5M15K-17K-726K266K-953K1.94M-757K691K
Other Non-Cash Items-5.06M1.12M2.66M3.75M1.54M-364K-387K-2.21M1.27M13.93M
Working Capital Changes-4.9M-2.37M1.78M39.92M6.44M-10.15M393K4.01M-25.55M-30.95M
Change in Receivables-1.36M-592K2.41M-119K-1.83M-13.11M-266K-17.51M13.92M-36.36M
Change in Inventory1.56M00-111K000000
Change in Payables2.42M1.93M-358K3.68M21.57M7.62M16.48M26.48M-44.77M14.34M
Cash from Investing+-9.2M-25.45M-30.89M-109.05M-25.59M-43.44M144.6M-53.85M-207.25M38.76M
Capital Expenditures-853K-5.46M-3.12M-3.42M-6.32M-6.26M-12.4M-13.13M-2.47M-1.99M
CapEx % of Revenue0.09%0.5%0.06%0.06%0.21%0.16%0.46%0.03%0.03%0.03%
Acquisitions----------
Investments----------
Other Investing-4.31M-19.99M-27.77M-105.63M-7.56M-1.96M-881K40.72M-1.6M-1.07M
Cash from Financing+1.52M64.78M49.95M91.43M193.66M308.98M8.01M108.58M81.85M-20.45M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing-232K-1.03M1.98M690K5.45M8.11M8.03M1.06M5.77M9.61M
Net Change in Cash----------
Free Cash Flow+-23.02M-40.71M-2.9M20.76M-95.73M-157.67M-205.74M130.98M-122.38M-113.11M
FCF Margin %-2.38%-3.7%-0.06%0.39%-3.24%-4.05%-7.71%0.32%-1.61%-1.48%
FCF Growth %-2.16%-0.77%0.93%8.15%-5.61%-0.65%-0.3%1.64%-1.93%0.08%
FCF per Share-1.16-2.07-0.140.71-2.52-3.13-3.952.01-1.78-1.49
FCF Conversion (FCF/Net Income)1.16x1.04x-0.02x-0.66x0.56x0.84x0.91x1.16x1.00x0.90x
Interest Paid0000000000
Taxes Paid0000000003.18M

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-66.1%-248.22%-16.59%--289.69%-55.08%-64.29%33.51%-24.78%-30.54%
Return on Invested Capital (ROIC)-222.57%-1528.42%-17.41%--91.4%-93.52%-126.3%98.03%-45.6%-32.9%
Gross Margin-152.62%-222.93%20.51%-7.37%-296.34%-338.75%100%100%-88.11%100%
Net Margin-198.45%-307.1%-20.1%-68.95%-492.27%-463.54%-794.01%30.14%-156.13%-160.8%
Debt / Equity0.00x0.49x0.00x-0.03x0.02x0.13x0.06x0.06x0.05x
Interest Coverage-1108.89x-39.86x-7.89x-199.56x------
FCF Conversion1.16x1.04x-0.02x-0.66x0.56x0.84x0.91x1.16x1.00x0.90x
Revenue Growth478.44%13.96%370.18%2.43%-44.28%31.84%-31.5%1446.03%-81.57%0.38%

Revenue by Segment

2018201920202021202220232024
Milestone Revenue------25M
Milestone Revenue Growth-------
Research Support Payments And Other Service-4.01M7.95M5.68M8.2M52.62M2.83M
Research Support Payments And Other Service Growth--98.08%-28.56%44.38%541.62%-94.61%
Royalty------100K
Royalty Growth-------
Licensing Fee----5M--
Licensing Fee Growth-------
Performance Milestone2M2M15M8M---
Performance Milestone Growth-0.00%650.00%-46.67%---
Partner Revenue--4M----
Partner Revenue Growth-------
Option Exercise Fee-7.5M-----
Option Exercise Fee Growth-------
Commercial License Option Exercise-3.5M-----
Commercial License Option Exercise Growth-------
License4M------
License Growth-------
Service, Other373K------
Service, Other Growth-------

Frequently Asked Questions

Growth & Financials

Zymeworks Inc. (ZYME) reported $134.5M in revenue for fiscal year 2024. This represents a 7953% increase from $1.7M in 2014.

Zymeworks Inc. (ZYME) grew revenue by 0.4% over the past year. Growth has been modest.

Zymeworks Inc. (ZYME) reported a net loss of $63.4M for fiscal year 2024.

Dividend & Returns

Zymeworks Inc. (ZYME) has a return on equity (ROE) of -30.5%. Negative ROE indicates the company is unprofitable.

Zymeworks Inc. (ZYME) had negative free cash flow of $66.2M in fiscal year 2024, likely due to heavy capital investments.

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