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ZYMEZymeworks Inc.
$29.63$2.2B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
Performance
P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
Live BreakoutsStock ScreenerOwnership
ZYME logo

Zymeworks Inc.

ZYME
NASDAQ · Oncology Biotech
$29.63
At close - Nov 6, 4:00 PM EST - USD
Market Cap$2.18B
P/E-14.4x
52W High$31.49
Volume903.14K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Revenue Collapse and Cash Burn Threaten Liquidity

Zymeworks' licensing-driven revenue spike in 2025Q2 ($48.7M) has reversed sharply, with revenue falling to zero in 2026Q2 and gross margin swinging to -18.2% in 2026Q1, indicating the end of its asset-light revenue model.

GrowthDecelerating
ProfitabilityNegative
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

ZYME price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

6/12 Beats

EPS beat 6 of last 12 quarters

02

Valuation risk

-139% Peers

P/E is 139% below peer median

03

Market leadership

RS 80 · Leader

High momentum (Outperforming 80% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystConfirmed earnings · Nov 9

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
ZYME+11.31%
S&P 500 (^GSPC)+7.63%
1-Year Return
ZYME+65.53%
S&P 500 (^GSPC)+9.69%
3-Year Return
ZYME+307.01%
S&P 500 (^GSPC)+75.77%
5-Year Return
ZYME+34.44%
S&P 500 (^GSPC)+61.51%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-14.4x
Forward P/E
24.9x
EV/EBITDA
N/A
FCF YieldCash Flow
N/A

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-14.4x
4.1x
0th· Low
EV/EBITDA
N/A
1.0x
N/A
Price/FCF
N/A
3.9x
N/A
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$1.47-95.0%
Base (Fair)$30.68+3.5%
Bull$2.42-91.8%
$1.47 Bear$30.68 Base$2.42 Bull
Current Market Price: $29.63
Trades at a 3.4% discount to Base DCF ($30.68)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$106M+38.9% YoY
Net income FY25
-$81M+33.9% YoY
Free cash flow FY25
-$35M+69.5% YoY
Operating margin FY25
-87.3%+92.4 pts YoY
ROIC (FY25)-25.9%
Avg ROIC 5Y-26.5%
ROE (TTM)-72.1%
Piotroski Score5 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate6/12 (50%)
Revenue Beat Rate7/12 (58%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.62-7.9%
vs -$0.57
$5M+1.2%
vs $5M
Q2 2026
May 7, 2026
-$0.59-490.0%
vs -$0.10
$2M-90.1%
vs $24M
Q2 2026
Mar 2, 2026
-$0.55-57.1%
vs -$0.35
$3M-86.9%
vs $19M
Q4 2025
Nov 6, 2025
-$0.26+13.3%
vs -$0.30
$28M+41.7%
vs $19M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Defense World·6d ago
Comparing Vericel (NASDAQ:VCEL) and Zymeworks (NASDAQ:ZYME)

Zymeworks (NASDAQ: ZYME - Get Free Report) and Vericel (NASDAQ: VCEL - Get Free Report) are both mid-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their dividends, analyst recommendations, institutional ownership, risk, profitability, earnings and valuation. Earnings and Valuation This table compares Zymeworks and Vericel"s

Zacks Investment Research·Oct 29, 2026
Zymeworks Inc. (ZYME) to Report Q3 Results: Wall Street Expects Earnings Growth

Zymeworks (ZYME) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.

MarketBeat·Oct 27, 2026
Zymeworks Highlights ZW191 Ovarian Cancer Responses, Roche Deal Upside

Zymeworks NASDAQ: ZYME outlined a partnering-focused research strategy, presented updated clinical data for its ZW191 antibody-drug conjugate in platinum-resistant ovarian cancer, and discussed its recently announced collaboration with Roche for the DLL3-targeting T-cell engager ZW209.

Seeking Alpha·Oct 27, 2026
Zymeworks Inc. (ZYME) Discusses Portfolio Strategy, Roche Partnership and Pipeline Updates Transcript

Zymeworks Inc. (ZYME) Discusses Portfolio Strategy, Roche Partnership and Pipeline Updates Transcript

Filtered for Zymeworks Inc.More Headlines
04

Compare before deciding

Benchmark ZYME against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Zymeworks Inc. (ZYME)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ZYME logoZYMEZymeworks Inc.Current
$29.63$2.18B-14.4238.87%-404%-72.07%—
IMVT logoIMVTImmunovant, Inc.
$30.53$6.3B-11.66—-7585.86%-69.59%—
RCUS logoRCUSArcus Biosciences, Inc.
$18.28$2.3B-5.23-4.26%-445%-90.04%—
AGIO logoAGIOAgios Pharmaceuticals, Inc.
$29.41$1.75B-4.7148.03%-264.76%-34.63%—
TPST logoTPSTTempest Therapeutics, Inc.
$0.38$5.79M-0.14——-1270.11%—
ABBV logoABBVAbbVie Inc.
$291.31$514.68B49.878.57%15.68%—2.26%

Compare ZYME vs Peers

Zymeworks Inc. (ZYME) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for ZYME.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ZYME against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, RCUS, AGIO, TPST

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

ZYME SEC Filings & Documents

Zymeworks Inc. (ZYME) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jun 29, 2026·SEC

Material company update

May 14, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 2, 2026·SEC

FY 2025

Mar 5, 2025·SEC

FY 2024

Mar 6, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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ZYME Frequently Asked Questions

Zymeworks Inc. (ZYME) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Zymeworks Inc.'s revenue?

Zymeworks Inc. (ZYME) reported $37.1M in revenue over the trailing twelve months. Revenue was $106.0M in fiscal year 2025. That is 6245% more than the $1.7M of fiscal year 2014.

How fast is Zymeworks Inc. growing?

Zymeworks Inc. (ZYME) revenue fell by 69.8% over the trailing twelve months, compared with the twelve months before.

Is ZYME profitable?

No. Zymeworks Inc. (ZYME) reported a net loss of $150.0M over the trailing twelve months.

Dividend & Returns
What is ZYME's return on equity?

Zymeworks Inc. (ZYME) had a return on equity (ROE) of -72.1% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Zymeworks Inc.'s free cash flow?

Zymeworks Inc. (ZYME) had negative free cash flow of $120.0M over the trailing twelve months.

What if you invested $1,000 in ZYME back in 2014?

Total return calculator · dividends reinvested · 12+ years of data

See returns →