Biotechnology
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Side-by-side financial analysisStock Comparison
INAB vs FATE vs ADCT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
INAB vs FATE vs ADCT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $6M | $221M | $127M |
| Revenue (TTM) | $0.00 | $6M | $79M |
| Net Income (TTM) | $-19M | $-130M | $-137M |
| Gross Margin | — | 53.8% | 90.7% |
| Operating Margin | — | -22.1% | -149.6% |
| Total Debt | $3M | $78M | $439M |
| Cash & Equiv. | $27M | $47M | $261M |
INAB vs FATE vs ADCT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 21 | Jun 26 | Return |
|---|---|---|---|
| IN8bio, Inc. (INAB) | 100 | 0.5 | -99.5% |
| Fate Therapeutics, … (FATE) | 100 | 2.3 | -97.7% |
| ADC Therapeutics S.… (ADCT) | 100 | 4.7 | -95.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: INAB vs FATE vs ADCT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
INAB has the current edge in this matchup, primarily because of its strength in sleep-well-at-night and defensive.
- Lower volatility, beta 1.89, Low D/E 10.1%, current ratio 8.82x
- Beta 1.89, current ratio 8.82x
- 32.1% revenue growth vs FATE's -51.2%
FATE is the clearest fit if your priority is long-term compounding.
- 8.0% 10Y total return vs ADCT's -96.6%
- +53.2% vs ADCT's -70.5%
- -39.4% ROA vs INAB's -80.2%, ROIC -36.5% vs -256.0%
ADCT is the clearest fit if your priority is income & stability and growth exposure.
- beta 1.84
- Rev growth 14.9%, EPS growth 30.9%, 3Y rev CAGR -27.1%
- Beta 1.84 vs FATE's 1.93
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 32.1% revenue growth vs FATE's -51.2% | |
| Quality / Margins | 1.3% margin vs FATE's -20.6% | |
| Stability / Safety | Beta 1.84 vs FATE's 1.93 | |
| Dividends | Tie | None of these 3 stocks pay a meaningful dividend |
| Momentum (1Y) | +53.2% vs ADCT's -70.5% | |
| Efficiency (ROA) | -39.4% ROA vs INAB's -80.2%, ROIC -36.5% vs -256.0% |
INAB vs FATE vs ADCT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
INAB vs FATE vs ADCT — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ADCT leads in 1 of 6 categories
INAB leads 0 • FATE leads 0 • 4 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ADCT leads this category, winning 6 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ADCT and INAB operate at a comparable scale, with $79M and $0 in trailing revenue. Profitability is closely matched — net margins range from -173.0% (ADCT) to -20.6% (FATE). On growth, ADCT holds the edge at -9.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $0 | $6M | $79M |
| EBITDAEarnings before interest/tax | -$17M | -$127M | -$117M |
| Net IncomeAfter-tax profit | -$19M | -$130M | -$137M |
| Free Cash FlowCash after capex | -$15M | -$108M | -$115M |
| Gross MarginGross profit ÷ Revenue | — | +53.8% | +90.7% |
| Operating MarginEBIT ÷ Revenue | — | -22.1% | -149.6% |
| Net MarginNet income ÷ Revenue | — | -20.6% | -173.0% |
| FCF MarginFCF ÷ Revenue | — | -17.1% | -144.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -20.3% | -9.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.9% | +18.8% | +41.7% |
Valuation Metrics
Evenly matched — INAB and FATE and ADCT each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $6M | $221M | $127M |
| Enterprise ValueMkt cap + debt − cash | -$18M | $253M | $304M |
| Trailing P/EPrice ÷ TTM EPS | -0.31x | -1.65x | -0.89x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 33.32x | 1.56x |
| Price / BookPrice ÷ Book value/share | 0.22x | 1.09x | — |
| Price / FCFMarket cap ÷ FCF | — | — | — |
Profitability & Efficiency
Evenly matched — INAB and FATE each lead in 4 of 8 comparable metrics.
Profitability & Efficiency
FATE delivers a -58.9% return on equity — every $100 of shareholder capital generates $-59 in annual profit, vs $-96 for INAB. INAB carries lower financial leverage with a 0.10x debt-to-equity ratio, signaling a more conservative balance sheet compared to FATE's 0.38x. On the Piotroski fundamental quality scale (0–9), INAB scores 5/9 vs FATE's 2/9, reflecting solid financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | -96.4% | -58.9% | — |
| ROA (TTM)Return on assets | -80.2% | -39.4% | -44.7% |
| ROICReturn on invested capital | -2.6% | -36.5% | — |
| ROCEReturn on capital employed | -84.5% | -43.1% | -43.8% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 2 | 4 |
| Debt / EquityFinancial leverage | 0.10x | 0.38x | — |
| Net DebtTotal debt minus cash | -$24M | $31M | $178M |
| Cash & Equiv.Liquid assets | $27M | $47M | $261M |
| Total DebtShort + long-term debt | $3M | $78M | $439M |
| Interest CoverageEBIT ÷ Interest expense | — | — | -1.72x |
Total Returns (Dividends Reinvested)
Evenly matched — FATE and ADCT each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADCT five years ago would be worth $433 today (with dividends reinvested), compared to $46 for INAB. Over the past 12 months, FATE leads with a +53.2% total return vs ADCT's -70.5%. The 3-year compound annual growth rate (CAGR) favors ADCT at -24.2% vs INAB's -71.3% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | -43.9% | +91.9% | -71.7% |
| 1-Year ReturnPast 12 months | -37.6% | +53.2% | -70.5% |
| 3-Year ReturnCumulative with dividends | -97.6% | -65.9% | -56.5% |
| 5-Year ReturnCumulative with dividends | -99.5% | -97.7% | -95.7% |
| 10-Year ReturnCumulative with dividends | -99.5% | +8.0% | -96.6% |
| CAGR (3Y)Annualised 3-year return | -71.3% | -30.2% | -24.2% |
Risk & Volatility
Evenly matched — FATE and ADCT each lead in 1 of 2 comparable metrics.
Risk & Volatility
ADCT is the less volatile stock with a 1.84 beta — it tends to amplify market swings less than FATE's 1.93 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FATE currently trades 66.0% from its 52-week high vs ADCT's 20.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.89x | 1.93x | 1.84x |
| 52-Week HighHighest price in past year | $2.73 | $2.88 | $4.97 |
| 52-Week LowLowest price in past year | $1.17 | $0.91 | $0.78 |
| % of 52W HighCurrent price vs 52-week peak | +50.5% | +66.0% | +20.0% |
| RSI (14)Momentum oscillator 0–100 | 38.9 | 48.9 | 14.8 |
| Avg Volume (50D)Average daily shares traded | 62K | 3.2M | 1.8M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: FATE as "Buy", ADCT as "Hold". Consensus price targets imply 251.3% upside for ADCT (target: $4) vs 189.5% for FATE (target: $6).
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Hold |
| Price TargetConsensus 12-month target | — | $5.50 | $3.50 |
| # AnalystsCovering analysts | — | 31 | 12 |
| Dividend YieldAnnual dividend ÷ price | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% |
ADCT leads in 1 of 6 categories — strongest in Income & Cash Flow. 4 categories are tied.
INAB vs FATE vs ADCT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is INAB or FATE or ADCT a better buy right now?
For growth investors, ADC Therapeutics S.
A. (ADCT) is the stronger pick with 14. 9% revenue growth year-over-year, versus -51. 2% for Fate Therapeutics, Inc. (FATE). Analysts rate Fate Therapeutics, Inc. (FATE) a "Buy" — based on 31 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — INAB or FATE or ADCT?
Over the past 5 years, ADC Therapeutics S.
A. (ADCT) delivered a total return of -95. 7%, compared to -99. 5% for IN8bio, Inc. (INAB). Over 10 years, the gap is even starker: FATE returned +8. 0% versus INAB's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — INAB or FATE or ADCT?
By beta (market sensitivity over 5 years), ADC Therapeutics S.
A. (ADCT) is the lower-risk stock at 1. 84β versus Fate Therapeutics, Inc. 's 1. 93β — meaning FATE is approximately 5% more volatile than ADCT relative to the S&P 500. On balance sheet safety, IN8bio, Inc. (INAB) carries a lower debt/equity ratio of 10% versus 38% for Fate Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — INAB or FATE or ADCT?
By revenue growth (latest reported year), ADC Therapeutics S.
A. (ADCT) is pulling ahead at 14. 9% versus -51. 2% for Fate Therapeutics, Inc. (FATE). On earnings-per-share growth, the picture is similar: ADC Therapeutics S. A. grew EPS 30. 9% year-over-year, compared to -678. 9% for IN8bio, Inc.. Over a 3-year CAGR, ADCT leads at -27. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — INAB or FATE or ADCT?
IN8bio, Inc.
(INAB) is the more profitable company, earning 0. 0% net margin versus -20. 5% for Fate Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INAB leads at 0. 0% versus -22. 2% for FATE. At the gross margin level — before operating expenses — ADCT leads at 90. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — INAB or FATE or ADCT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is INAB or FATE or ADCT better for a retirement portfolio?
For long-horizon retirement investors, ADC Therapeutics S.
A. (ADCT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. IN8bio, Inc. (INAB) carries a higher beta of 1. 89 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ADCT: -96. 6%, INAB: -99. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between INAB and FATE and ADCT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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