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INVA vs PRGO vs GSK
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - General
INVA vs PRGO vs GSK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - General |
| Market Cap | $1.69B | $1.62B | $101.38B |
| Revenue (TTM) | $424M | $4.18B | $33.34B |
| Net Income (TTM) | $504M | $-1.82B | $6.40B |
| Gross Margin | 76.2% | 34.2% | 72.9% |
| Operating Margin | 14.8% | -4.1% | 26.9% |
| Forward P/E | 7.3x | 5.5x | 10.4x |
| Total Debt | $269M | $3.97B | $17.69B |
| Cash & Equiv. | $551M | $532M | $3.39B |
INVA vs PRGO vs GSK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Innoviva, Inc. (INVA) | 100 | 163.9 | +63.9% |
| Perrigo Company plc (PRGO) | 100 | 21.4 | -78.6% |
| GSK plc (GSK) | 100 | 120.3 | +20.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: INVA vs PRGO vs GSK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
INVA carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
- 95.6% 10Y total return vs GSK's 62.8%
- Lower volatility, beta 0.11, Low D/E 22.9%, current ratio 14.64x
PRGO is the clearest fit if your priority is income & stability.
- Dividend streak 10 yrs, beta 1.21, yield 9.8%
- 9.8% yield, 10-year raise streak, vs GSK's 6.6%, (1 stock pays no dividend)
GSK is the clearest fit if your priority is momentum.
- +41.5% vs PRGO's -52.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 18.5% revenue growth vs PRGO's -2.8% | |
| Value | Lower P/E (7.3x vs 10.4x), PEG 0.71 vs 0.73 | |
| Quality / Margins | 118.9% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.11 vs PRGO's 1.21, lower leverage | |
| Dividends | 9.8% yield, 10-year raise streak, vs GSK's 6.6%, (1 stock pays no dividend) | |
| Momentum (1Y) | +41.5% vs PRGO's -52.0% | |
| Efficiency (ROA) | 32.4% ROA vs PRGO's -19.8%, ROIC 14.2% vs 3.7% |
INVA vs PRGO vs GSK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
INVA vs PRGO vs GSK — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
INVA leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
GSK is the larger business by revenue, generating $33.3B annually — 78.6x INVA's $424M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, INVA holds the edge at +10.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $424M | $4.2B | $33.3B |
| EBITDAEarnings before interest/tax | $86M | $58M | $11.7B |
| Net IncomeAfter-tax profit | $504M | -$1.8B | $6.4B |
| Free Cash FlowCash after capex | $181M | $108M | $7.4B |
| Gross MarginGross profit ÷ Revenue | +76.2% | +34.2% | +72.9% |
| Operating MarginEBIT ÷ Revenue | +14.8% | -4.1% | +26.9% |
| Net MarginNet income ÷ Revenue | +118.9% | -43.5% | +19.2% |
| FCF MarginFCF ÷ Revenue | +42.6% | +2.6% | +22.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +10.6% | -7.2% | +1.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +4.0% | -56.4% | +10.3% |
Valuation Metrics
PRGO leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 6.7x trailing earnings, GSK trades at a 4% valuation discount to INVA's 6.9x P/E. Adjusting for growth (PEG ratio), GSK offers better value at 0.47x vs INVA's 0.67x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $1.7B | $1.6B | $101.4B |
| Enterprise ValueMkt cap + debt − cash | $1.4B | $5.1B | $120.8B |
| Trailing P/EPrice ÷ TTM EPS | 6.94x | -1.14x | 6.68x |
| Forward P/EPrice ÷ next-FY EPS est. | 7.31x | 5.53x | 10.40x |
| PEG RatioP/E ÷ EPS growth rate | 0.67x | — | 0.47x |
| EV / EBITDAEnterprise value multiple | 6.90x | 7.43x | 8.36x |
| Price / SalesMarket cap ÷ Revenue | 3.97x | 0.38x | 2.29x |
| Price / BookPrice ÷ Book value/share | 1.65x | 0.55x | 2.40x |
| Price / FCFMarket cap ÷ FCF | 8.63x | 11.17x | 12.83x |
Profitability & Efficiency
INVA leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 47.6% return on equity — every $100 of shareholder capital generates $48 in annual profit, vs $-51 for PRGO. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), GSK scores 8/9 vs PRGO's 4/9, reflecting strong financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | +47.6% | -50.7% | +31.5% |
| ROA (TTM)Return on assets | +32.4% | -19.8% | +8.3% |
| ROICReturn on invested capital | +14.2% | +3.7% | +22.1% |
| ROCEReturn on capital employed | +12.4% | +4.3% | +21.5% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 8 |
| Debt / EquityFinancial leverage | 0.23x | 1.35x | 1.11x |
| Net DebtTotal debt minus cash | -$282M | $3.4B | $14.3B |
| Cash & Equiv.Liquid assets | $551M | $532M | $3.4B |
| Total DebtShort + long-term debt | $269M | $4.0B | $17.7B |
| Interest CoverageEBIT ÷ Interest expense | 63.45x | -7.20x | 12.86x |
Total Returns (Dividends Reinvested)
INVA leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,448 today (with dividends reinvested), compared to $3,969 for PRGO. Over the past 12 months, GSK leads with a +41.5% total return vs PRGO's -52.0%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.1% vs PRGO's -25.2% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | +15.2% | -13.6% | +2.5% |
| 1-Year ReturnPast 12 months | +23.2% | -52.0% | +41.5% |
| 3-Year ReturnCumulative with dividends | +96.0% | -58.1% | +50.1% |
| 5-Year ReturnCumulative with dividends | +94.5% | -60.3% | +52.6% |
| 10-Year ReturnCumulative with dividends | +95.6% | -77.7% | +62.8% |
| CAGR (3Y)Annualised 3-year return | +25.1% | -25.2% | +14.5% |
Risk & Volatility
INVA leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.11 beta — it tends to amplify market swings less than PRGO's 1.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 91.0% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.11x | 1.21x | 0.44x |
| 52-Week HighHighest price in past year | $25.15 | $28.44 | $61.70 |
| 52-Week LowLowest price in past year | $16.52 | $9.23 | $35.45 |
| % of 52W HighCurrent price vs 52-week peak | +91.0% | +41.2% | +81.7% |
| RSI (14)Momentum oscillator 0–100 | 44.7 | 53.1 | 31.6 |
| Avg Volume (50D)Average daily shares traded | 604K | 3.3M | 4.3M |
Analyst Outlook
PRGO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: INVA as "Buy", PRGO as "Hold", GSK as "Hold". Consensus price targets imply 209.1% upside for PRGO (target: $36) vs 4.0% for GSK (target: $52). For income investors, PRGO offers the higher dividend yield at 9.82% vs GSK's 6.56%.
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold | Hold |
| Price TargetConsensus 12-month target | $40.00 | $36.20 | $52.45 |
| # AnalystsCovering analysts | 10 | 36 | 29 |
| Dividend YieldAnnual dividend ÷ price | — | +9.8% | +6.6% |
| Dividend StreakConsecutive years of raises | 0 | 10 | 1 |
| Dividend / ShareAnnual DPS | — | $1.15 | $2.44 |
| Buyback YieldShare repurchases ÷ mkt cap | +0.3% | 0.0% | 0.0% |
INVA leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRGO leads in 2 (Valuation Metrics, Analyst Outlook).
INVA vs PRGO vs GSK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is INVA or PRGO or GSK a better buy right now?
For growth investors, Innoviva, Inc.
(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). GSK plc (GSK) offers the better valuation at 6. 7x trailing P/E (10. 4x forward), making it the more compelling value choice. Analysts rate Innoviva, Inc. (INVA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — INVA or PRGO or GSK?
On trailing P/E, GSK plc (GSK) is the cheapest at 6.
7x versus Innoviva, Inc. at 6. 9x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 5x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Innoviva, Inc. wins at 0. 71x versus GSK plc's 0. 73x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — INVA or PRGO or GSK?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 5%, compared to -60. 3% for Perrigo Company plc (PRGO). Over 10 years, the gap is even starker: INVA returned +95. 6% versus PRGO's -77. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — INVA or PRGO or GSK?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 11β versus Perrigo Company plc's 1. 21β — meaning PRGO is approximately 968% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
05Which is growing faster — INVA or PRGO or GSK?
By revenue growth (latest reported year), Innoviva, Inc.
(INVA) is pulling ahead at 18. 5% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, INVA leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — INVA or PRGO or GSK?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus 8. 1% for PRGO. At the gross margin level — before operating expenses — GSK leads at 72. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is INVA or PRGO or GSK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Innoviva, Inc. (INVA) is the more undervalued stock at a PEG of 0. 71x versus GSK plc's 0. 73x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 5x forward P/E versus 10. 4x for GSK plc — 4. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 209. 1% to $36. 20.
08Which pays a better dividend — INVA or PRGO or GSK?
In this comparison, PRGO (9.
8% yield), GSK (6. 6% yield) pay a dividend. INVA does not pay a meaningful dividend and should not be held primarily for income.
09Is INVA or PRGO or GSK better for a retirement portfolio?
For long-horizon retirement investors, GSK plc (GSK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
44), 6. 6% yield). Both have compounded well over 10 years (GSK: +62. 8%, PRGO: -77. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between INVA and PRGO and GSK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: INVA is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; GSK is a mid-cap deep-value stock. PRGO, GSK pay a dividend while INVA does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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