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Stock Comparison

PRQR vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
PRQR
ProQR Therapeutics N.V.

Biotechnology

HealthcareNASDAQ • NL
Market Cap$152M
5Y Perf.-76.3%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$239M
5Y Perf.-88.3%

PRQR vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
PRQR logoPRQR
EDIT logoEDIT
IndustryBiotechnologyBiotechnology
Market Cap$152M$239M
Revenue (TTM)$13M$39M
Net Income (TTM)$-46M$-109M
Gross Margin89.7%98.8%
Operating Margin-345.5%-297.5%
Total Debt$14M$77M
Cash & Equiv.$92M$147M

PRQR vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

PRQR
EDIT
StockJun 20Jun 26Return
ProQR Therapeutics … (PRQR)10023.7-76.3%
Editas Medicine, In… (EDIT)10011.7-88.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: PRQR vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: EDIT leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. ProQR Therapeutics N.V. is the stronger pick specifically for capital preservation and lower volatility and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
🥇EDIT emerged as the overall leader. Track its performance:
PRQR
ProQR Therapeutics N.V.
The Income Pick

PRQR is the clearest fit if your priority is income & stability and long-term compounding.

  • beta 1.62
  • -68.2% 10Y total return vs EDIT's -91.9%
  • Lower volatility, beta 1.62, Low D/E 28.3%, current ratio 3.09x
Best for: income & stability and long-term compounding
EDIT
Editas Medicine, Inc.
The Growth Play

EDIT carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 25.4%, EPS growth 37.5%, 3Y rev CAGR 27.1%
  • 25.4% revenue growth vs PRQR's -19.2%
  • -281.6% margin vs PRQR's -339.4%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthEDIT logoEDIT25.4% revenue growth vs PRQR's -19.2%
Quality / MarginsEDIT logoEDIT-281.6% margin vs PRQR's -339.4%
Stability / SafetyPRQR logoPRQRBeta 1.62 vs EDIT's 2.63, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)EDIT logoEDIT+20.2% vs PRQR's -20.9%
Efficiency (ROA)PRQR logoPRQR-38.5% ROA vs EDIT's -58.2%

PRQR vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
PRQRProQR Therapeutics N.V.
FY 2024
Up-front payments
75.4%$16M
Milestone payments
24.6%$5M
EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

PRQR vs EDIT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLPRQRLAGGINGEDIT

Income & Cash Flow (Last 12 Months)

EDIT leads this category, winning 5 of 6 comparable metrics.

EDIT is the larger business by revenue, generating $39M annually — 2.9x PRQR's $13M. Profitability is closely matched — net margins range from -2.8% (EDIT) to -3.4% (PRQR). On growth, EDIT holds the edge at -39.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricPRQR logoPRQRProQR Therapeutic…EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$13M$39M
EBITDAEarnings before interest/tax-$44M-$111M
Net IncomeAfter-tax profit-$46M-$109M
Free Cash FlowCash after capex-$49M-$141M
Gross MarginGross profit ÷ Revenue+89.7%+98.8%
Operating MarginEBIT ÷ Revenue-3.5%-3.0%
Net MarginNet income ÷ Revenue-3.4%-2.8%
FCF MarginFCF ÷ Revenue-3.6%-3.6%
Rev. Growth (YoY)Latest quarter vs prior year-54.3%-39.2%
EPS Growth (YoY)Latest quarter vs prior year-30.0%+71.7%
EDIT leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

PRQR leads this category, winning 2 of 3 comparable metrics.
MetricPRQR logoPRQRProQR Therapeutic…EDIT logoEDITEditas Medicine, …
Market CapShares × price$152M$239M
Enterprise ValueMkt cap + debt − cash$61M$169M
Trailing P/EPrice ÷ TTM EPS-3.28x-1.36x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue8.60x5.90x
Price / BookPrice ÷ Book value/share2.66x7.94x
Price / FCFMarket cap ÷ FCF
PRQR leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

PRQR leads this category, winning 7 of 7 comparable metrics.

PRQR delivers a -86.5% return on equity — every $100 of shareholder capital generates $-86 in annual profit, vs $-7 for EDIT. PRQR carries lower financial leverage with a 0.28x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 2.81x.

MetricPRQR logoPRQRProQR Therapeutic…EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-86.5%-6.8%
ROA (TTM)Return on assets-38.5%-58.2%
ROICReturn on invested capital
ROCEReturn on capital employed-40.3%-49.1%
Piotroski ScoreFundamental quality 0–911
Debt / EquityFinancial leverage0.28x2.81x
Net DebtTotal debt minus cash-$78M-$70M
Cash & Equiv.Liquid assets$92M$147M
Total DebtShort + long-term debt$14M$77M
Interest CoverageEBIT ÷ Interest expense-48.66x-91.80x
PRQR leads this category, winning 7 of 7 comparable metrics.

Total Returns (Dividends Reinvested)

PRQR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in PRQR five years ago would be worth $2,130 today (with dividends reinvested), compared to $652 for EDIT. Over the past 12 months, EDIT leads with a +20.2% total return vs PRQR's -20.9%. The 3-year compound annual growth rate (CAGR) favors PRQR at -4.4% vs EDIT's -37.4% — a key indicator of consistent wealth creation.

MetricPRQR logoPRQRProQR Therapeutic…EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date-27.6%+19.0%
1-Year ReturnPast 12 months-20.9%+20.2%
3-Year ReturnCumulative with dividends-12.7%-75.4%
5-Year ReturnCumulative with dividends-78.7%-93.5%
10-Year ReturnCumulative with dividends-68.2%-91.9%
CAGR (3Y)Annualised 3-year return-4.4%-37.4%
PRQR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — PRQR and EDIT each lead in 1 of 2 comparable metrics.

PRQR is the less volatile stock with a 1.62 beta — it tends to amplify market swings less than EDIT's 2.63 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EDIT currently trades 53.7% from its 52-week high vs PRQR's 46.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricPRQR logoPRQRProQR Therapeutic…EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5001.62x2.63x
52-Week HighHighest price in past year$3.10$4.54
52-Week LowLowest price in past year$1.33$1.66
% of 52W HighCurrent price vs 52-week peak+46.5%+53.7%
RSI (14)Momentum oscillator 0–10040.239.8
Avg Volume (50D)Average daily shares traded651K2.1M
Evenly matched — PRQR and EDIT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates PRQR as "Buy" and EDIT as "Buy". Consensus price targets imply 152.1% upside for PRQR (target: $4) vs 104.9% for EDIT (target: $5).

MetricPRQR logoPRQRProQR Therapeutic…EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$3.63$5.00
# AnalystsCovering analysts1025
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

PRQR leads in 3 of 6 categories (Valuation Metrics, Profitability & Efficiency). EDIT leads in 1 (Income & Cash Flow). 1 tied.

Best OverallProQR Therapeutics N.V. (PRQR)Leads 3 of 6 categories
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PRQR vs EDIT: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is PRQR or EDIT a better buy right now?

For growth investors, Editas Medicine, Inc.

(EDIT) is the stronger pick with 25. 4% revenue growth year-over-year, versus -19. 2% for ProQR Therapeutics N. V. (PRQR). Analysts rate ProQR Therapeutics N. V. (PRQR) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — PRQR or EDIT?

Over the past 5 years, ProQR Therapeutics N.

V. (PRQR) delivered a total return of -78. 7%, compared to -93. 5% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: PRQR returned -68. 2% versus EDIT's -91. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — PRQR or EDIT?

By beta (market sensitivity over 5 years), ProQR Therapeutics N.

V. (PRQR) is the lower-risk stock at 1. 62β versus Editas Medicine, Inc. 's 2. 63β — meaning EDIT is approximately 62% more volatile than PRQR relative to the S&P 500. On balance sheet safety, ProQR Therapeutics N. V. (PRQR) carries a lower debt/equity ratio of 28% versus 3% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — PRQR or EDIT?

By revenue growth (latest reported year), Editas Medicine, Inc.

(EDIT) is pulling ahead at 25. 4% versus -19. 2% for ProQR Therapeutics N. V. (PRQR). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -11. 8% for ProQR Therapeutics N. V.. Over a 3-year CAGR, PRQR leads at 62. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — PRQR or EDIT?

ProQR Therapeutics N.

V. (PRQR) is the more profitable company, earning -265. 2% net margin versus -395. 0% for Editas Medicine, Inc. — meaning it keeps -265. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at -245. 2% versus -275. 9% for PRQR. At the gross margin level — before operating expenses — EDIT leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — PRQR or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is PRQR or EDIT better for a retirement portfolio?

For long-horizon retirement investors, ProQR Therapeutics N.

V. (PRQR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 63 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PRQR: -68. 2%, EDIT: -91. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between PRQR and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: PRQR is a small-cap quality compounder stock; EDIT is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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