Biotechnology
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EDIT vs CRSP
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
EDIT vs CRSP — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $298M | $4.92B |
| Revenue (TTM) | $0.00 | $37M |
| Net Income (TTM) | $-160M | $-488M |
| Gross Margin | — | -355.3% |
| Operating Margin | — | -15.6% |
| Total Debt | $18M | $207M |
| Cash & Equiv. | $147M | $348M |
EDIT vs CRSP — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Editas Medicine, In… (EDIT) | 100 | 11.7 | -88.3% |
| CRISPR Therapeutics… (CRSP) | 100 | 85.3 | -14.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: EDIT vs CRSP
Each card shows where this stock fits in a portfolio — not just who wins on paper.
EDIT is the clearest fit if your priority is momentum.
- +97.4% vs CRSP's +39.2%
CRSP carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.93
- Rev growth -90.0%, EPS growth -49.1%, 3Y rev CAGR 100.4%
- 271.8% 10Y total return vs EDIT's -90.5%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -90.0% revenue growth vs EDIT's -100.0% | |
| Stability / Safety | Beta 1.93 vs EDIT's 2.52, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +97.4% vs CRSP's +39.2% | |
| Efficiency (ROA) | -21.7% ROA vs EDIT's -74.2% |
EDIT vs CRSP — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
EDIT vs CRSP — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
EDIT leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
CRSP and EDIT operate at a comparable scale, with $37M and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $37M |
| EBITDAEarnings before interest/tax | $0 | -$556M |
| Net IncomeAfter-tax profit | -$160M | -$488M |
| Free Cash FlowCash after capex | -$166M | -$303M |
| Gross MarginGross profit ÷ Revenue | — | -3.6% |
| Operating MarginEBIT ÷ Revenue | — | -15.6% |
| Net MarginNet income ÷ Revenue | — | -13.3% |
| FCF MarginFCF ÷ Revenue | — | -8.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | -151.6% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +105.5% | -15.8% |
Valuation Metrics
CRSP leads this category, winning 2 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $298M | $4.9B |
| Enterprise ValueMkt cap + debt − cash | $169M | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -1.69x | -8.10x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 1400.87x |
| Price / BookPrice ÷ Book value/share | 9.89x | 2.45x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
CRSP leads this category, winning 5 of 6 comparable metrics.
Profitability & Efficiency
CRSP delivers a -25.5% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-5 for EDIT. CRSP carries lower financial leverage with a 0.11x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), CRSP scores 2/9 vs EDIT's 1/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -5.2% | -25.5% |
| ROA (TTM)Return on assets | -74.2% | -21.7% |
| ROICReturn on invested capital | — | -27.4% |
| ROCEReturn on capital employed | — | -31.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 |
| Debt / EquityFinancial leverage | 0.66x | 0.11x |
| Net DebtTotal debt minus cash | -$129M | -$141M |
| Cash & Equiv.Liquid assets | $147M | $348M |
| Total DebtShort + long-term debt | $18M | $207M |
| Interest CoverageEBIT ÷ Interest expense | — | — |
Total Returns (Dividends Reinvested)
CRSP leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CRSP five years ago would be worth $4,599 today (with dividends reinvested), compared to $876 for EDIT. Over the past 12 months, EDIT leads with a +97.4% total return vs CRSP's +39.2%. The 3-year compound annual growth rate (CAGR) favors CRSP at -2.1% vs EDIT's -32.2% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +48.3% | -2.6% |
| 1-Year ReturnPast 12 months | +97.4% | +39.2% |
| 3-Year ReturnCumulative with dividends | -68.9% | -6.1% |
| 5-Year ReturnCumulative with dividends | -91.2% | -54.0% |
| 10-Year ReturnCumulative with dividends | -90.5% | +271.8% |
| CAGR (3Y)Annualised 3-year return | -32.2% | -2.1% |
Risk & Volatility
Evenly matched — EDIT and CRSP each lead in 1 of 2 comparable metrics.
Risk & Volatility
CRSP is the less volatile stock with a 1.93 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.52x | 1.93x |
| 52-Week HighHighest price in past year | $4.54 | $78.48 |
| 52-Week LowLowest price in past year | $1.29 | $33.03 |
| % of 52W HighCurrent price vs 52-week peak | +67.0% | +66.7% |
| RSI (14)Momentum oscillator 0–100 | 52.5 | 52.5 |
| Avg Volume (50D)Average daily shares traded | 1.7M | 2.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates EDIT as "Buy" and CRSP as "Buy". Consensus price targets imply 97.4% upside for EDIT (target: $6) vs 20.3% for CRSP (target: $63).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $6.00 | $63.00 |
| # AnalystsCovering analysts | 25 | 38 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.4% |
CRSP leads in 3 of 6 categories (Valuation Metrics, Profitability & Efficiency). EDIT leads in 1 (Income & Cash Flow). 1 tied.
EDIT vs CRSP: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is EDIT or CRSP a better buy right now?
For growth investors, CRISPR Therapeutics AG (CRSP) is the stronger pick with -90.
0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Editas Medicine, Inc. (EDIT) a "Buy" — based on 25 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — EDIT or CRSP?
Over the past 5 years, CRISPR Therapeutics AG (CRSP) delivered a total return of -54.
0%, compared to -91. 2% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: CRSP returned +271. 8% versus EDIT's -90. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — EDIT or CRSP?
By beta (market sensitivity over 5 years), CRISPR Therapeutics AG (CRSP) is the lower-risk stock at 1.
93β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 31% more volatile than CRSP relative to the S&P 500. On balance sheet safety, CRISPR Therapeutics AG (CRSP) carries a lower debt/equity ratio of 11% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — EDIT or CRSP?
By revenue growth (latest reported year), CRISPR Therapeutics AG (CRSP) is pulling ahead at -90.
0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -49. 1% for CRISPR Therapeutics AG. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — EDIT or CRSP?
Editas Medicine, Inc.
(EDIT) is the more profitable company, earning 0. 0% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -189. 3% for CRSP. At the gross margin level — before operating expenses — EDIT leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — EDIT or CRSP?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is EDIT or CRSP better for a retirement portfolio?
For long-horizon retirement investors, CRISPR Therapeutics AG (CRSP) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+271.
8% 10Y return). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CRSP: +271. 8%, EDIT: -90. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between EDIT and CRSP?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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