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TENX vs ATHA vs NKTR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TENX
Tenax Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$69M
5Y Perf.-99.5%
ATHA
Athira Pharma, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$17M
5Y Perf.-97.4%
NKTR
Nektar Therapeutics

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.69B
5Y Perf.-66.5%

TENX vs ATHA vs NKTR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TENX logoTENX
ATHA logoATHA
NKTR logoNKTR
IndustryBiotechnologyBiotechnologyBiotechnology
Market Cap$69M$17M$1.69B
Revenue (TTM)$0.00$0.00$55M
Net Income (TTM)$-43M$-129M$-164M
Gross Margin99.6%
Operating Margin-237.9%
Total Debt$0.00$803K$149M
Cash & Equiv.$95M$69M$15M

TENX vs ATHA vs NKTRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TENX
ATHA
NKTR
StockSep 20May 26Return
Tenax Therapeutics,… (TENX)1000.5-99.5%
Athira Pharma, Inc. (ATHA)1002.6-97.4%
Nektar Therapeutics (NKTR)10033.5-66.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: TENX vs ATHA vs NKTR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TENX leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Nektar Therapeutics is the stronger pick specifically for recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
TENX
Tenax Therapeutics, Inc.
The Income Pick

TENX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 1 yrs, beta 0.90
  • EPS growth 96.3%
  • Lower volatility, beta 0.90, current ratio 20.60x
Best for: income & stability and growth exposure
ATHA
Athira Pharma, Inc.
The Secondary Option

ATHA plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
NKTR
Nektar Therapeutics
The Long-Run Compounder

NKTR is the clearest fit if your priority is long-term compounding.

  • -59.1% 10Y total return vs ATHA's -97.5%
  • +8.2% vs ATHA's +81.6%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthTENX logoTENX428.0% revenue growth vs ATHA's -64.6%
Quality / MarginsTENX logoTENX2.0% margin vs NKTR's -297.1%
Stability / SafetyTENX logoTENXBeta 0.90 vs NKTR's 1.85
DividendsTieNone of these 3 stocks pay a meaningful dividend
Momentum (1Y)NKTR logoNKTR+8.2% vs ATHA's +81.6%
Efficiency (ROA)TENX logoTENX-42.1% ROA vs ATHA's -225.7%

TENX vs ATHA vs NKTR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TENXTenax Therapeutics, Inc.
FY 2013
United States
100.0%$46,016
ATHAAthira Pharma, Inc.

Segment breakdown not available.

NKTRNektar Therapeutics
FY 2025
Non Cash Royalty Revenue Related To Sale Of Future Royalties
99.5%$55M
License Collaboration And Other Revenue
0.5%$300,000

TENX vs ATHA vs NKTR — Financial Metrics

Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLTENXLAGGINGNKTR

Income & Cash Flow (Last 12 Months)

ATHA leads this category, winning 1 of 1 comparable metric.

NKTR and ATHA operate at a comparable scale, with $55M and $0 in trailing revenue.

MetricTENX logoTENXTenax Therapeutic…ATHA logoATHAAthira Pharma, In…NKTR logoNKTRNektar Therapeuti…
RevenueTrailing 12 months$0$0$55M
EBITDAEarnings before interest/tax-$43M-$110M-$130M
Net IncomeAfter-tax profit-$43M-$129M-$164M
Free Cash FlowCash after capex-$26M-$52M-$209M
Gross MarginGross profit ÷ Revenue+99.6%
Operating MarginEBIT ÷ Revenue-2.4%
Net MarginNet income ÷ Revenue-3.0%
FCF MarginFCF ÷ Revenue-3.8%
Rev. Growth (YoY)Latest quarter vs prior year-25.3%
EPS Growth (YoY)Latest quarter vs prior year-110.5%+24.8%-4.5%
ATHA leads this category, winning 1 of 1 comparable metric.

Valuation Metrics

Evenly matched — TENX and ATHA each lead in 1 of 2 comparable metrics.
MetricTENX logoTENXTenax Therapeutic…ATHA logoATHAAthira Pharma, In…NKTR logoNKTRNektar Therapeuti…
Market CapShares × price$69M$17M$1.7B
Enterprise ValueMkt cap + debt − cash-$26M-$30M$1.8B
Trailing P/EPrice ÷ TTM EPS-10.13x-0.17x-8.57x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue30.64x
Price / BookPrice ÷ Book value/share1.93x0.37x15.66x
Price / FCFMarket cap ÷ FCF
Evenly matched — TENX and ATHA each lead in 1 of 2 comparable metrics.

Profitability & Efficiency

TENX leads this category, winning 6 of 8 comparable metrics.

TENX delivers a -45.0% return on equity — every $100 of shareholder capital generates $-45 in annual profit, vs $-4 for NKTR. ATHA carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), TENX scores 3/9 vs NKTR's 2/9, reflecting mixed financial health.

MetricTENX logoTENXTenax Therapeutic…ATHA logoATHAAthira Pharma, In…NKTR logoNKTRNektar Therapeuti…
ROE (TTM)Return on equity-45.0%-3.8%-4.0%
ROA (TTM)Return on assets-42.1%-2.3%-62.8%
ROICReturn on invested capital-57.2%
ROCEReturn on capital employed-39.0%-2.3%-55.7%
Piotroski ScoreFundamental quality 0–9322
Debt / EquityFinancial leverage0.03x1.66x
Net DebtTotal debt minus cash-$95M-$68M$134M
Cash & Equiv.Liquid assets$95M$69M$15M
Total DebtShort + long-term debt$0$803,000$149M
Interest CoverageEBIT ÷ Interest expense-847.57x-4.74x
TENX leads this category, winning 6 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

NKTR leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in NKTR five years ago would be worth $2,765 today (with dividends reinvested), compared to $35 for TENX. Over the past 12 months, NKTR leads with a +818.2% total return vs ATHA's +81.6%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs ATHA's -46.7% — a key indicator of consistent wealth creation.

MetricTENX logoTENXTenax Therapeutic…ATHA logoATHAAthira Pharma, In…NKTR logoNKTRNektar Therapeuti…
YTD ReturnYear-to-date+5.4%-37.6%+92.0%
1-Year ReturnPast 12 months+109.2%+81.6%+818.2%
3-Year ReturnCumulative with dividends-55.1%-84.8%+621.8%
5-Year ReturnCumulative with dividends-99.6%-97.7%-72.3%
10-Year ReturnCumulative with dividends-100.0%-97.5%-59.1%
CAGR (3Y)Annualised 3-year return-23.4%-46.7%+93.3%
NKTR leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — TENX and NKTR each lead in 1 of 2 comparable metrics.

TENX is the less volatile stock with a 0.90 beta — it tends to amplify market swings less than NKTR's 1.85 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NKTR currently trades 76.5% from its 52-week high vs ATHA's 51.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTENX logoTENXTenax Therapeutic…ATHA logoATHAAthira Pharma, In…NKTR logoNKTRNektar Therapeuti…
Beta (5Y)Sensitivity to S&P 5000.90x1.47x1.85x
52-Week HighHighest price in past year$18.38$8.36$109.00
52-Week LowLowest price in past year$5.34$2.30$7.99
% of 52W HighCurrent price vs 52-week peak+63.4%+51.9%+76.5%
RSI (14)Momentum oscillator 0–10038.438.453.4
Avg Volume (50D)Average daily shares traded520K46K991K
Evenly matched — TENX and NKTR each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricTENX logoTENXTenax Therapeutic…ATHA logoATHAAthira Pharma, In…NKTR logoNKTRNektar Therapeuti…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$132.83
# AnalystsCovering analysts33
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ATHA leads in 1 of 6 categories (Income & Cash Flow). TENX leads in 1 (Profitability & Efficiency). 2 tied.

Best OverallTenax Therapeutics, Inc. (TENX)Leads 1 of 6 categories
Loading custom metrics...

TENX vs ATHA vs NKTR: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is TENX or ATHA or NKTR a better buy right now?

Analysts rate Nektar Therapeutics (NKTR) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison.

The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — TENX or ATHA or NKTR?

Over the past 5 years, Nektar Therapeutics (NKTR) delivered a total return of -72.

3%, compared to -99. 6% for Tenax Therapeutics, Inc. (TENX). Over 10 years, the gap is even starker: NKTR returned -59. 1% versus TENX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — TENX or ATHA or NKTR?

By beta (market sensitivity over 5 years), Tenax Therapeutics, Inc.

(TENX) is the lower-risk stock at 0. 90β versus Nektar Therapeutics's 1. 85β — meaning NKTR is approximately 105% more volatile than TENX relative to the S&P 500. On balance sheet safety, Athira Pharma, Inc. (ATHA) carries a lower debt/equity ratio of 3% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.

04

Which is growing faster — TENX or ATHA or NKTR?

On earnings-per-share growth, the picture is similar: Tenax Therapeutics, Inc.

grew EPS 96. 3% year-over-year, compared to -12. 1% for Nektar Therapeutics. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — TENX or ATHA or NKTR?

Tenax Therapeutics, Inc.

(TENX) is the more profitable company, earning 0. 0% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TENX leads at 0. 0% versus -236. 8% for NKTR. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — TENX or ATHA or NKTR?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is TENX or ATHA or NKTR better for a retirement portfolio?

For long-horizon retirement investors, Tenax Therapeutics, Inc.

(TENX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 90)). Nektar Therapeutics (NKTR) carries a higher beta of 1. 85 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (TENX: -100. 0%, NKTR: -59. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between TENX and ATHA and NKTR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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