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Stock Comparison

TXG vs BRKR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TXG
10x Genomics, Inc.

Medical - Healthcare Information Services

HealthcareNASDAQ • US
Market Cap$2.93B
5Y Perf.-71.2%
BRKR
Bruker Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$6.44B
5Y Perf.+1.0%

TXG vs BRKR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TXG logoTXG
BRKR logoBRKR
IndustryMedical - Healthcare Information ServicesMedical - Devices
Market Cap$2.93B$6.44B
Revenue (TTM)$643M$3.46B
Net Income (TTM)$-44M$-26M
Gross Margin69.1%45.3%
Operating Margin-9.5%4.9%
Forward P/E20.7x
Total Debt$158M$2.04B
Cash & Equiv.$474M$299M

TXG vs BRKRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TXG
BRKR
StockMay 20May 26Return
10x Genomics, Inc. (TXG)10028.8-71.2%
Bruker Corporation (BRKR)100101.0+1.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: TXG vs BRKR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BRKR leads in 4 of 7 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. 10x Genomics, Inc. is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
TXG
10x Genomics, Inc.
The Growth Play

TXG is the clearest fit if your priority is growth exposure and sleep-well-at-night.

  • Rev growth 5.2%, EPS growth 77.0%, 3Y rev CAGR 7.6%
  • Lower volatility, beta 2.32, Low D/E 19.8%, current ratio 4.46x
  • 5.2% revenue growth vs BRKR's 2.1%
Best for: growth exposure and sleep-well-at-night
BRKR
Bruker Corporation
The Income Pick

BRKR carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 0 yrs, beta 1.59, yield 0.4%
  • 59.6% 10Y total return vs TXG's -56.9%
  • Beta 1.59, yield 0.4%, current ratio 1.73x
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthTXG logoTXG5.2% revenue growth vs BRKR's 2.1%
ValueTXG logoTXGBetter valuation composite
Quality / MarginsBRKR logoBRKR-0.8% margin vs TXG's -6.8%
Stability / SafetyBRKR logoBRKRBeta 1.59 vs TXG's 2.32
DividendsBRKR logoBRKR0.4% yield; the other pay no meaningful dividend
Momentum (1Y)TXG logoTXG+180.7% vs BRKR's +7.7%
Efficiency (ROA)BRKR logoBRKR-0.4% ROA vs TXG's -4.4%, ROIC 4.4% vs -17.9%

TXG vs BRKR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TXG10x Genomics, Inc.
FY 2025
Product And Service Revenue
48.1%$597M
Consumables
40.9%$507M
Instruments
4.6%$57M
Licensing And Royalty Revenue
3.7%$46M
Service
2.6%$33M
BRKRBruker Corporation
FY 2025
Product
80.5%$2.8B
Product and Service, Other
19.5%$670M

TXG vs BRKR — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBRKRLAGGINGTXG

Income & Cash Flow (Last 12 Months)

Evenly matched — TXG and BRKR each lead in 3 of 6 comparable metrics.

BRKR is the larger business by revenue, generating $3.5B annually — 5.4x TXG's $643M. BRKR is the more profitable business, keeping -0.8% of every revenue dollar as net income compared to TXG's -6.8%.

MetricTXG logoTXG10x Genomics, Inc.BRKR logoBRKRBruker Corporation
RevenueTrailing 12 months$643M$3.5B
EBITDAEarnings before interest/tax-$29M$339M
Net IncomeAfter-tax profit-$44M-$26M
Free Cash FlowCash after capex$130M$51M
Gross MarginGross profit ÷ Revenue+69.1%+45.3%
Operating MarginEBIT ÷ Revenue-9.5%+4.9%
Net MarginNet income ÷ Revenue-6.8%-0.8%
FCF MarginFCF ÷ Revenue+20.2%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year+0.6%+2.7%
EPS Growth (YoY)Latest quarter vs prior year+67.5%-81.8%
Evenly matched — TXG and BRKR each lead in 3 of 6 comparable metrics.

Valuation Metrics

BRKR leads this category, winning 3 of 4 comparable metrics.
MetricTXG logoTXG10x Genomics, Inc.BRKR logoBRKRBruker Corporation
Market CapShares × price$2.9B$6.4B
Enterprise ValueMkt cap + debt − cash$2.6B$8.2B
Trailing P/EPrice ÷ TTM EPS-64.97x-282.00x
Forward P/EPrice ÷ next-FY EPS est.20.68x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple17.93x
Price / SalesMarket cap ÷ Revenue4.56x1.87x
Price / BookPrice ÷ Book value/share3.56x2.56x
Price / FCFMarket cap ÷ FCF22.54x148.71x
BRKR leads this category, winning 3 of 4 comparable metrics.

Profitability & Efficiency

BRKR leads this category, winning 5 of 8 comparable metrics.

BRKR delivers a -1.1% return on equity — every $100 of shareholder capital generates $-1 in annual profit, vs $-6 for TXG. TXG carries lower financial leverage with a 0.20x debt-to-equity ratio, signaling a more conservative balance sheet compared to BRKR's 0.81x.

MetricTXG logoTXG10x Genomics, Inc.BRKR logoBRKRBruker Corporation
ROE (TTM)Return on equity-5.7%-1.1%
ROA (TTM)Return on assets-4.4%-0.4%
ROICReturn on invested capital-17.9%+4.4%
ROCEReturn on capital employed-13.1%+5.0%
Piotroski ScoreFundamental quality 0–944
Debt / EquityFinancial leverage0.20x0.81x
Net DebtTotal debt minus cash-$316M$1.7B
Cash & Equiv.Liquid assets$474M$299M
Total DebtShort + long-term debt$158M$2.0B
Interest CoverageEBIT ÷ Interest expense-7374.83x0.75x
BRKR leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

BRKR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in BRKR five years ago would be worth $6,345 today (with dividends reinvested), compared to $1,574 for TXG. Over the past 12 months, TXG leads with a +180.7% total return vs BRKR's +7.7%. The 3-year compound annual growth rate (CAGR) favors BRKR at -17.8% vs TXG's -25.3% — a key indicator of consistent wealth creation.

MetricTXG logoTXG10x Genomics, Inc.BRKR logoBRKRBruker Corporation
YTD ReturnYear-to-date+36.8%-12.0%
1-Year ReturnPast 12 months+180.7%+7.7%
3-Year ReturnCumulative with dividends-58.3%-44.4%
5-Year ReturnCumulative with dividends-84.3%-36.6%
10-Year ReturnCumulative with dividends-56.9%+59.6%
CAGR (3Y)Annualised 3-year return-25.3%-17.8%
BRKR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — TXG and BRKR each lead in 1 of 2 comparable metrics.

BRKR is the less volatile stock with a 1.59 beta — it tends to amplify market swings less than TXG's 2.32 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TXG currently trades 86.0% from its 52-week high vs BRKR's 75.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTXG logoTXG10x Genomics, Inc.BRKR logoBRKRBruker Corporation
Beta (5Y)Sensitivity to S&P 5002.32x1.59x
52-Week HighHighest price in past year$26.45$56.22
52-Week LowLowest price in past year$7.72$28.53
% of 52W HighCurrent price vs 52-week peak+86.0%+75.2%
RSI (14)Momentum oscillator 0–10049.652.6
Avg Volume (50D)Average daily shares traded2.3M1.9M
Evenly matched — TXG and BRKR each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates TXG as "Hold" and BRKR as "Buy". Consensus price targets imply 23.2% upside for BRKR (target: $52) vs -2.6% for TXG (target: $22). BRKR is the only dividend payer here at 0.36% yield — a key consideration for income-focused portfolios.

MetricTXG logoTXG10x Genomics, Inc.BRKR logoBRKRBruker Corporation
Analyst RatingConsensus buy/hold/sellHoldBuy
Price TargetConsensus 12-month target$22.14$52.13
# AnalystsCovering analysts2232
Dividend YieldAnnual dividend ÷ price+0.4%
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS$0.15
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

BRKR leads in 3 of 6 categories — strongest in Valuation Metrics and Profitability & Efficiency. 2 categories are tied.

Best OverallBruker Corporation (BRKR)Leads 3 of 6 categories
Loading custom metrics...

TXG vs BRKR: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is TXG or BRKR a better buy right now?

For growth investors, 10x Genomics, Inc.

(TXG) is the stronger pick with 5. 2% revenue growth year-over-year, versus 2. 1% for Bruker Corporation (BRKR). Analysts rate Bruker Corporation (BRKR) a "Buy" — based on 32 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — TXG or BRKR?

Over the past 5 years, Bruker Corporation (BRKR) delivered a total return of -36.

6%, compared to -84. 3% for 10x Genomics, Inc. (TXG). Over 10 years, the gap is even starker: BRKR returned +67. 1% versus TXG's -57. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — TXG or BRKR?

By beta (market sensitivity over 5 years), Bruker Corporation (BRKR) is the lower-risk stock at 1.

59β versus 10x Genomics, Inc. 's 2. 32β — meaning TXG is approximately 46% more volatile than BRKR relative to the S&P 500. On balance sheet safety, 10x Genomics, Inc. (TXG) carries a lower debt/equity ratio of 20% versus 81% for Bruker Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — TXG or BRKR?

By revenue growth (latest reported year), 10x Genomics, Inc.

(TXG) is pulling ahead at 5. 2% versus 2. 1% for Bruker Corporation (BRKR). On earnings-per-share growth, the picture is similar: 10x Genomics, Inc. grew EPS 77. 0% year-over-year, compared to -119. 7% for Bruker Corporation. Over a 3-year CAGR, BRKR leads at 10. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — TXG or BRKR?

Bruker Corporation (BRKR) is the more profitable company, earning -0.

3% net margin versus -6. 8% for 10x Genomics, Inc. — meaning it keeps -0. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BRKR leads at 6. 9% versus -17. 2% for TXG. At the gross margin level — before operating expenses — TXG leads at 69. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is TXG or BRKR more undervalued right now?

Analyst consensus price targets imply the most upside for BRKR: 23.

2% to $52. 13.

07

Which pays a better dividend — TXG or BRKR?

In this comparison, BRKR (0.

4% yield) pays a dividend. TXG does not pay a meaningful dividend and should not be held primarily for income.

08

Is TXG or BRKR better for a retirement portfolio?

For long-horizon retirement investors, Bruker Corporation (BRKR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding.

10x Genomics, Inc. (TXG) carries a higher beta of 2. 32 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BRKR: +67. 1%, TXG: -57. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between TXG and BRKR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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TXG

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 41%
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BRKR

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 27%
  • Dividend Yield > 0.5%
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