Biotechnology
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YDES vs NUVB
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
YDES vs NUVB — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $22M | $1.75B |
| Revenue (TTM) | $0.00 | $143M |
| Net Income (TTM) | $-3M | $-146M |
| Gross Margin | 30.4% | 91.6% |
| Operating Margin | -286.5% | -105.0% |
| Total Debt | $23K | $10M |
| Cash & Equiv. | $3M | $164M |
Quick Verdict: YDES vs NUVB
Each card shows where this stock fits in a portfolio — not just who wins on paper.
YDES is the clearest fit if your priority is income & stability and sleep-well-at-night.
- beta 0.81
- Lower volatility, beta 0.81, Low D/E 0.3%, current ratio 13.18x
- Beta 0.81, current ratio 13.18x
NUVB carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 7.0%, EPS growth 71.6%
- -49.6% 10Y total return vs YDES's -56.9%
- 7.0% revenue growth vs YDES's 45.8%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 7.0% revenue growth vs YDES's 45.8% | |
| Quality / Margins | -102.1% margin vs YDES's -276.6% | |
| Stability / Safety | Beta 0.81 vs NUVB's 2.04, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +141.1% vs YDES's -56.9% | |
| Efficiency (ROA) | -23.8% ROA vs YDES's -100.8%, ROIC -54.3% vs -63.3% |
YDES vs NUVB — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
YDES vs NUVB — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
NUVB leads this category, winning 5 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
NUVB and YDES operate at a comparable scale, with $143M and $0 in trailing revenue. Profitability is closely matched — net margins range from -102.1% (NUVB) to -2.8% (YDES).
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $143M |
| EBITDAEarnings before interest/tax | -$3M | -$145M |
| Net IncomeAfter-tax profit | -$3M | -$146M |
| Free Cash FlowCash after capex | -$1M | -$126M |
| Gross MarginGross profit ÷ Revenue | +30.4% | +91.6% |
| Operating MarginEBIT ÷ Revenue | -2.9% | -105.0% |
| Net MarginNet income ÷ Revenue | -2.8% | -102.1% |
| FCF MarginFCF ÷ Revenue | -9.3% | -88.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +26.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -116.0% | +106.3% |
Valuation Metrics
YDES leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $22M | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $18M | $1.6B |
| Trailing P/EPrice ÷ TTM EPS | -9.27x | -8.40x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 42.19x | 27.82x |
| Price / BookPrice ÷ Book value/share | 3.27x | 5.63x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
NUVB leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
YDES delivers a -42.7% return on equity — every $100 of shareholder capital generates $-43 in annual profit, vs $-44 for NUVB. YDES carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NUVB's 0.03x. On the Piotroski fundamental quality scale (0–9), NUVB scores 4/9 vs YDES's 3/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -42.7% | -44.1% |
| ROA (TTM)Return on assets | -100.8% | -23.8% |
| ROICReturn on invested capital | -63.3% | -54.3% |
| ROCEReturn on capital employed | -44.1% | -42.8% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.03x |
| Net DebtTotal debt minus cash | -$3M | -$154M |
| Cash & Equiv.Liquid assets | $3M | $164M |
| Total DebtShort + long-term debt | $22,555 | $10M |
| Interest CoverageEBIT ÷ Interest expense | -1893.69x | -162.11x |
Total Returns (Dividends Reinvested)
NUVB leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NUVB five years ago would be worth $4,574 today (with dividends reinvested), compared to $4,314 for YDES. Over the past 12 months, NUVB leads with a +141.1% total return vs YDES's -56.9%. The 3-year compound annual growth rate (CAGR) favors NUVB at 46.0% vs YDES's -24.4% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -56.7% | -41.3% |
| 1-Year ReturnPast 12 months | -56.9% | +141.1% |
| 3-Year ReturnCumulative with dividends | -56.9% | +211.1% |
| 5-Year ReturnCumulative with dividends | -56.9% | -54.3% |
| 10-Year ReturnCumulative with dividends | -56.9% | -49.6% |
| CAGR (3Y)Annualised 3-year return | -24.4% | +46.0% |
Risk & Volatility
Evenly matched — YDES and NUVB each lead in 1 of 2 comparable metrics.
Risk & Volatility
YDES is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than NUVB's 2.04 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NUVB currently trades 51.7% from its 52-week high vs YDES's 20.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.81x | 2.04x |
| 52-Week HighHighest price in past year | $25.00 | $9.75 |
| 52-Week LowLowest price in past year | $4.73 | $1.57 |
| % of 52W HighCurrent price vs 52-week peak | +20.8% | +51.7% |
| RSI (14)Momentum oscillator 0–100 | 38.8 | 54.0 |
| Avg Volume (50D)Average daily shares traded | 20K | 4.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $12.40 |
| # AnalystsCovering analysts | — | 9 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
NUVB leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). YDES leads in 1 (Valuation Metrics). 1 tied.
YDES vs NUVB: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is YDES or NUVB a better buy right now?
For growth investors, Nuvation Bio Inc.
(NUVB) is the stronger pick with 699. 0% revenue growth year-over-year, versus 45. 8% for YD Bio Limited Ordinary Shares (YDES). Analysts rate Nuvation Bio Inc. (NUVB) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — YDES or NUVB?
Over the past 5 years, Nuvation Bio Inc.
(NUVB) delivered a total return of -54. 3%, compared to -56. 9% for YD Bio Limited Ordinary Shares (YDES). Over 10 years, the gap is even starker: NUVB returned -51. 8% versus YDES's -56. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — YDES or NUVB?
By beta (market sensitivity over 5 years), YD Bio Limited Ordinary Shares (YDES) is the lower-risk stock at 0.
81β versus Nuvation Bio Inc. 's 2. 04β — meaning NUVB is approximately 151% more volatile than YDES relative to the S&P 500. On balance sheet safety, YD Bio Limited Ordinary Shares (YDES) carries a lower debt/equity ratio of 0% versus 3% for Nuvation Bio Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — YDES or NUVB?
By revenue growth (latest reported year), Nuvation Bio Inc.
(NUVB) is pulling ahead at 699. 0% versus 45. 8% for YD Bio Limited Ordinary Shares (YDES). Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — YDES or NUVB?
YD Bio Limited Ordinary Shares (YDES) is the more profitable company, earning -276.
6% net margin versus -325. 3% for Nuvation Bio Inc. — meaning it keeps -276. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: YDES leads at -286. 5% versus -338. 7% for NUVB. At the gross margin level — before operating expenses — NUVB leads at 86. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — YDES or NUVB?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is YDES or NUVB better for a retirement portfolio?
For long-horizon retirement investors, YD Bio Limited Ordinary Shares (YDES) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
81)). Nuvation Bio Inc. (NUVB) carries a higher beta of 2. 04 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (YDES: -56. 1%, NUVB: -51. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between YDES and NUVB?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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