Medical - Healthcare Information Services
Compare Stocks
5 / 10Stock Comparison
ACON vs XTNT vs GKOS vs MDXG vs ATEC
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Devices
Medical - Devices
Biotechnology
Medical - Devices
ACON vs XTNT vs GKOS vs MDXG vs ATEC — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Healthcare Information Services | Medical - Devices | Medical - Devices | Biotechnology | Medical - Devices |
| Market Cap | $3M | $80M | $7.85B | $548M | $1.17B |
| Revenue (TTM) | $75.73B | $133M | $551M | $389M | $595M |
| Net Income (TTM) | $-7.23T | $2M | $-189M | $31M | $-125M |
| Gross Margin | 9.0% | 62.0% | 78.1% | 81.0% | 89.6% |
| Operating Margin | -93.1% | 4.8% | -15.6% | 10.2% | -9.6% |
| Forward P/E | — | — | — | 295.2x | 27.1x |
| Total Debt | $0.00 | $35M | $140M | $23M | $620M |
| Cash & Equiv. | $12.02T | $6M | $91M | $166M | $161M |
ACON vs XTNT vs GKOS vs MDXG vs ATEC — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Apr 22 | May 26 | Return |
|---|---|---|---|
| Aclarion, Inc. (ACON) | 100 | 0.0 | -100.0% |
| Xtant Medical Holdi… (XTNT) | 100 | 87.8 | -12.2% |
| Glaukos Corporation (GKOS) | 100 | 283.7 | +183.7% |
| MiMedx Group, Inc. (MDXG) | 100 | 93.4 | -6.6% |
| Alphatec Holdings, … (ATEC) | 100 | 71.4 | -28.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ACON vs XTNT vs GKOS vs MDXG vs ATEC
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ACON has the current edge in this matchup, primarily because of its strength in growth exposure and defensive.
- Rev growth 1000K%, EPS growth 99.8%, 3Y rev CAGR 106.8%
- Beta 0.98, yield 100.0%, current ratio 14.81x
- 1000K% revenue growth vs MDXG's 20.0%
- 100.0% yield; 1-year raise streak; the other 4 pay no meaningful dividend
XTNT ranks third and is worth considering specifically for income & stability and sleep-well-at-night.
- beta 0.69
- Lower volatility, beta 0.69, Low D/E 81.8%, current ratio 2.35x
- Beta 0.69 vs MDXG's 1.22
GKOS is the clearest fit if your priority is long-term compounding.
- 457.1% 10Y total return vs ATEC's 225.4%
- +52.0% vs ACON's -56.2%
MDXG is the #2 pick in this set and the best alternative if quality and efficiency is your priority.
- 7.9% margin vs ACON's -95.5%
- 9.7% ROA vs ACON's -211.6%, ROIC 42.3% vs -12.9%
ATEC is the clearest fit if your priority is value.
- Better valuation composite
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 1000K% revenue growth vs MDXG's 20.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 7.9% margin vs ACON's -95.5% | |
| Stability / Safety | Beta 0.69 vs MDXG's 1.22 | |
| Dividends | 100.0% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +52.0% vs ACON's -56.2% | |
| Efficiency (ROA) | 9.7% ROA vs ACON's -211.6%, ROIC 42.3% vs -12.9% |
ACON vs XTNT vs GKOS vs MDXG vs ATEC — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ACON vs XTNT vs GKOS vs MDXG vs ATEC — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MDXG leads in 2 of 6 categories
GKOS leads 1 • ACON leads 0 • XTNT leads 0 • ATEC leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
MDXG leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ACON is the larger business by revenue, generating $75.7B annually — 569.0x XTNT's $133M. MDXG is the more profitable business, keeping 7.9% of every revenue dollar as net income compared to ACON's -95.5%. On growth, ACON holds the edge at +999999.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $75.7B | $133M | $551M | $389M | $595M |
| EBITDAEarnings before interest/tax | -$7.05T | $11M | -$40M | $53M | $4M |
| Net IncomeAfter-tax profit | -$7.23T | $2M | -$189M | $31M | -$125M |
| Free Cash FlowCash after capex | -$7.16T | $5M | -$18M | $66M | $7M |
| Gross MarginGross profit ÷ Revenue | +9.0% | +62.0% | +78.1% | +81.0% | +89.6% |
| Operating MarginEBIT ÷ Revenue | -93.1% | +4.8% | -15.6% | +10.2% | -9.6% |
| Net MarginNet income ÷ Revenue | -95.5% | +1.3% | -34.3% | +7.9% | -21.1% |
| FCF MarginFCF ÷ Revenue | -94.6% | +3.9% | -3.4% | +17.0% | +1.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | +999999.0% | +19.0% | +41.2% | -33.1% | -100.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +99.9% | +123.7% | -6.3% | -2.4% | +37.1% |
Valuation Metrics
Evenly matched — ACON and MDXG each lead in 2 of 6 comparable metrics.
Valuation Metrics
On an enterprise value basis, MDXG's 5.1x EV/EBITDA is more attractive than ATEC's 3752.1x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $3M | $80M | $7.9B | $548M | $1.2B |
| Enterprise ValueMkt cap + debt − cash | -$12.02T | $109M | $7.9B | $405M | $1.6B |
| Trailing P/EPrice ÷ TTM EPS | -0.23x | -4.75x | -40.90x | 11.53x | -8.07x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 295.20x | 27.09x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 5.14x | 3752.09x |
| Price / SalesMarket cap ÷ Revenue | 0.00x | 0.68x | 15.47x | 1.31x | 1.54x |
| Price / BookPrice ÷ Book value/share | 0.00x | 1.77x | 11.69x | 2.15x | 32.28x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 7.51x | 422.56x |
Profitability & Efficiency
MDXG leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
MDXG delivers a 12.9% return on equity — every $100 of shareholder capital generates $13 in annual profit, vs $-4 for ATEC. MDXG carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to ATEC's 17.21x. On the Piotroski fundamental quality scale (0–9), ATEC scores 6/9 vs XTNT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -2.3% | +3.8% | -26.5% | +12.9% | -4.4% |
| ROA (TTM)Return on assets | -2.1% | +1.8% | -20.1% | +9.7% | -15.8% |
| ROICReturn on invested capital | -12.9% | -12.8% | -9.2% | +42.3% | -12.6% |
| ROCEReturn on capital employed | -109.9% | -17.9% | -10.3% | +25.7% | -13.7% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 3 | 5 | 6 |
| Debt / EquityFinancial leverage | — | 0.82x | 0.21x | 0.09x | 17.21x |
| Net DebtTotal debt minus cash | -$12.02T | $29M | $49M | -$144M | $459M |
| Cash & Equiv.Liquid assets | $12.02T | $6M | $91M | $166M | $161M |
| Total DebtShort + long-term debt | $0 | $35M | $140M | $23M | $620M |
| Interest CoverageEBIT ÷ Interest expense | — | 1.55x | -18.69x | 25.32x | -3.29x |
Total Returns (Dividends Reinvested)
GKOS leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in GKOS five years ago would be worth $16,155 today (with dividends reinvested), compared to $0 for ACON. Over the past 12 months, GKOS leads with a +52.0% total return vs ACON's -56.2%. The 3-year compound annual growth rate (CAGR) favors GKOS at 31.7% vs ACON's -96.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -36.5% | -24.0% | +21.2% | -43.1% | -62.7% |
| 1-Year ReturnPast 12 months | -56.2% | +10.0% | +52.0% | -47.1% | -37.8% |
| 3-Year ReturnCumulative with dividends | -100.0% | -12.3% | +128.7% | -36.6% | -47.8% |
| 5-Year ReturnCumulative with dividends | -100.0% | -66.1% | +61.5% | -62.9% | -48.7% |
| 10-Year ReturnCumulative with dividends | -100.0% | -97.8% | +457.1% | -48.5% | +225.4% |
| CAGR (3Y)Annualised 3-year return | -96.9% | -4.3% | +31.7% | -14.1% | -19.5% |
Risk & Volatility
Evenly matched — XTNT and GKOS each lead in 1 of 2 comparable metrics.
Risk & Volatility
XTNT is the less volatile stock with a 0.69 beta — it tends to amplify market swings less than MDXG's 1.22 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GKOS currently trades 91.4% from its 52-week high vs ACON's 26.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.98x | 0.69x | 1.20x | 1.22x | 1.13x |
| 52-Week HighHighest price in past year | $12.03 | $0.95 | $146.75 | $7.99 | $23.29 |
| 52-Week LowLowest price in past year | $2.34 | $0.44 | $73.16 | $3.02 | $6.85 |
| % of 52W HighCurrent price vs 52-week peak | +26.3% | +60.0% | +91.4% | +46.2% | +33.3% |
| RSI (14)Momentum oscillator 0–100 | 48.3 | 60.9 | 63.0 | 49.3 | 26.8 |
| Avg Volume (50D)Average daily shares traded | 103K | 142K | 678K | 1.4M | 3.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: GKOS as "Buy", MDXG as "Buy", ATEC as "Buy". Consensus price targets imply 222.6% upside for ATEC (target: $25) vs 9.3% for GKOS (target: $147). ACON is the only dividend payer here at 100.00% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | — | $146.67 | $10.00 | $25.00 |
| # AnalystsCovering analysts | — | — | 24 | 15 | 16 |
| Dividend YieldAnnual dividend ÷ price | +100.0% | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | — | — | — | — |
| Dividend / ShareAnnual DPS | $10196.68 | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +45.0% | 0.0% | 0.0% | +0.6% | 0.0% |
MDXG leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). GKOS leads in 1 (Total Returns). 2 tied.
ACON vs XTNT vs GKOS vs MDXG vs ATEC: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ACON or XTNT or GKOS or MDXG or ATEC a better buy right now?
For growth investors, Aclarion, Inc.
(ACON) is the stronger pick with 999999% revenue growth year-over-year, versus 20. 0% for MiMedx Group, Inc. (MDXG). MiMedx Group, Inc. (MDXG) offers the better valuation at 11. 5x trailing P/E (295. 2x forward), making it the more compelling value choice. Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ACON or XTNT or GKOS or MDXG or ATEC?
On forward P/E, Alphatec Holdings, Inc.
is actually cheaper at 27. 1x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — ACON or XTNT or GKOS or MDXG or ATEC?
Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +61.
5%, compared to -100. 0% for Aclarion, Inc. (ACON). Over 10 years, the gap is even starker: GKOS returned +457. 1% versus ACON's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ACON or XTNT or GKOS or MDXG or ATEC?
By beta (market sensitivity over 5 years), Xtant Medical Holdings, Inc.
(XTNT) is the lower-risk stock at 0. 69β versus MiMedx Group, Inc. 's 1. 22β — meaning MDXG is approximately 77% more volatile than XTNT relative to the S&P 500. On balance sheet safety, MiMedx Group, Inc. (MDXG) carries a lower debt/equity ratio of 9% versus 17% for Alphatec Holdings, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ACON or XTNT or GKOS or MDXG or ATEC?
By revenue growth (latest reported year), Aclarion, Inc.
(ACON) is pulling ahead at 999999% versus 20. 0% for MiMedx Group, Inc. (MDXG). On earnings-per-share growth, the picture is similar: Aclarion, Inc. grew EPS 99. 8% year-over-year, compared to -18. 4% for Glaukos Corporation. Over a 3-year CAGR, ACON leads at 106. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ACON or XTNT or GKOS or MDXG or ATEC?
MiMedx Group, Inc.
(MDXG) is the more profitable company, earning 11. 6% net margin versus -95. 5% for Aclarion, Inc. — meaning it keeps 11. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MDXG leads at 15. 3% versus -93. 1% for ACON. At the gross margin level — before operating expenses — MDXG leads at 82. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ACON or XTNT or GKOS or MDXG or ATEC more undervalued right now?
On forward earnings alone, Alphatec Holdings, Inc.
(ATEC) trades at 27. 1x forward P/E versus 295. 2x for MiMedx Group, Inc. — 268. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ATEC: 222. 6% to $25. 00.
08Which pays a better dividend — ACON or XTNT or GKOS or MDXG or ATEC?
In this comparison, ACON (100.
0% yield) pays a dividend. XTNT, GKOS, MDXG, ATEC do not pay a meaningful dividend and should not be held primarily for income.
09Is ACON or XTNT or GKOS or MDXG or ATEC better for a retirement portfolio?
For long-horizon retirement investors, Aclarion, Inc.
(ACON) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 98), 100. 0% yield). Both have compounded well over 10 years (ACON: -100. 0%, MDXG: -48. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ACON and XTNT and GKOS and MDXG and ATEC?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
ACON pays a dividend while XTNT, GKOS, MDXG, ATEC do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.