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ACTU
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HRZN
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HTGC
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Stock Comparison

ACTU vs TPVG vs IMVT vs HRZN vs HTGC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ACTU
Actuate Therapeutics Inc

Biotechnology

HealthcareNASDAQ • US
Market Cap$48M
5Y Perf.-74.9%
TPVG
TriplePoint Venture Growth BDC Corp.

Asset Management

Financial ServicesNYSE • US
Market Cap$226M
5Y Perf.-26.0%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.+8.8%
HRZN
Horizon Technology Finance Corporation

Asset Management

Financial ServicesNASDAQ • US
Market Cap$192M
5Y Perf.-60.5%
HTGC
Hercules Capital, Inc.

Asset Management

Financial ServicesNYSE • US
Market Cap$2.90B
5Y Perf.-19.1%

ACTU vs TPVG vs IMVT vs HRZN vs HTGC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ACTU logoACTU
TPVG logoTPVG
IMVT logoIMVT
HRZN logoHRZN
HTGC logoHTGC
IndustryBiotechnologyAsset ManagementBiotechnologyAsset ManagementAsset Management
Market Cap$48M$226M$6.90B$192M$2.90B
Revenue (TTM)$0.00$61M$0.00$75M$578M
Net Income (TTM)$-22M$-12M$-506M$28M$289M
Gross Margin72.9%35.7%88.3%
Operating Margin-35.9%26.0%65.8%
Forward P/E6.0x6.5x8.1x
Total Debt$405K$469M$72K$473M$2.30B
Cash & Equiv.$13M$20M$902M$106M$57M

ACTU vs TPVG vs IMVT vs HRZN vs HTGCLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ACTU
TPVG
IMVT
HRZN
HTGC
StockAug 24Jun 26Return
Actuate Therapeutic… (ACTU)10025.1-74.9%
TriplePoint Venture… (TPVG)10074.0-26.0%
Immunovant, Inc. (IMVT)100108.8+8.8%
Horizon Technology … (HRZN)10039.5-60.5%
Hercules Capital, I… (HTGC)10080.9-19.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: ACTU vs TPVG vs IMVT vs HRZN vs HTGC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HTGC leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Horizon Technology Finance Corporation is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. TPVG and IMVT also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇HTGC emerged as the overall leader. Track its performance:
ACTU
Actuate Therapeutics Inc
The Healthcare Pick

Among these 5 stocks, ACTU doesn't own a clear edge in any measured category.

Best for: healthcare exposure
TPVG
TriplePoint Venture Growth BDC Corp.
The Banking Pick

TPVG ranks third and is worth considering specifically for growth exposure.

  • Rev growth 36.6%, EPS growth 48.8%
  • 36.6% NII/revenue growth vs IMVT's -22.2%
Best for: growth exposure
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding.

  • 237.9% 10Y total return vs HTGC's 164.1%
  • +110.9% vs ACTU's -76.5%
Best for: long-term compounding
HRZN
Horizon Technology Finance Corporation
The Banking Pick

HRZN is the #2 pick in this set and the best alternative if income & stability and valuation efficiency is your priority.

  • Dividend streak 1 yrs, beta 0.85, yield 28.8%
  • PEG 0.27 vs TPVG's 5.88
  • Lower P/E (6.5x vs 8.1x)
  • 28.8% yield, 1-year raise streak, vs TPVG's 18.4%, (2 stocks pay no dividend)
Best for: income & stability and valuation efficiency
HTGC
Hercules Capital, Inc.
The Banking Pick

HTGC carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.

  • Lower volatility, beta 0.64, current ratio 1.44x
  • Beta 0.64, yield 9.1%, current ratio 1.44x
  • NIM 9.1% vs HRZN's 7.1%
  • 50.1% margin vs TPVG's -19.5%
Best for: sleep-well-at-night and defensive
See the full category breakdown
CategoryWinnerWhy
GrowthTPVG logoTPVG36.6% NII/revenue growth vs IMVT's -22.2%
ValueHRZN logoHRZNLower P/E (6.5x vs 8.1x)
Quality / MarginsHTGC logoHTGC50.1% margin vs TPVG's -19.5%
Stability / SafetyHTGC logoHTGCBeta 0.64 vs ACTU's 2.21
DividendsHRZN logoHRZN28.8% yield, 1-year raise streak, vs TPVG's 18.4%, (2 stocks pay no dividend)
Momentum (1Y)IMVT logoIMVT+110.9% vs ACTU's -76.5%
Efficiency (ROA)HTGC logoHTGC6.4% ROA vs ACTU's -180.9%

ACTU vs TPVG vs IMVT vs HRZN vs HTGC — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHTGCLAGGINGACTU

Income & Cash Flow (Last 12 Months)

HTGC leads this category, winning 3 of 5 comparable metrics.

HTGC and IMVT operate at a comparable scale, with $578M and $0 in trailing revenue. HTGC is the more profitable business, keeping 50.1% of every revenue dollar as net income compared to TPVG's -19.5%.

MetricACTU logoACTUActuate Therapeut…TPVG logoTPVGTriplePoint Ventu…IMVT logoIMVTImmunovant, Inc.HRZN logoHRZNHorizon Technolog…HTGC logoHTGCHercules Capital,…
RevenueTrailing 12 months$0$61M$0$75M$578M
EBITDAEarnings before interest/tax-$22M-$22M-$532M$19M$381M
Net IncomeAfter-tax profit-$22M-$12M-$506M$28M$289M
Free Cash FlowCash after capex-$20M-$59M-$407M$67M-$352M
Gross MarginGross profit ÷ Revenue+72.9%+35.7%+88.3%
Operating MarginEBIT ÷ Revenue-35.9%+26.0%+65.8%
Net MarginNet income ÷ Revenue-19.5%+37.4%+50.1%
FCF MarginFCF ÷ Revenue-97.1%+89.6%-60.8%
Rev. Growth (YoY)Latest quarter vs prior year
EPS Growth (YoY)Latest quarter vs prior year+25.0%-2.3%-14.1%-29.6%-20.7%
HTGC leads this category, winning 3 of 5 comparable metrics.

Valuation Metrics

TPVG leads this category, winning 3 of 6 comparable metrics.

At 4.2x trailing earnings, HRZN trades at a 50% valuation discount to HTGC's 8.4x P/E. Adjusting for growth (PEG ratio), HRZN offers better value at 0.17x vs TPVG's 4.50x — a lower PEG means you pay less per unit of expected earnings growth.

MetricACTU logoACTUActuate Therapeut…TPVG logoTPVGTriplePoint Ventu…IMVT logoIMVTImmunovant, Inc.HRZN logoHRZNHorizon Technolog…HTGC logoHTGCHercules Capital,…
Market CapShares × price$48M$226M$6.9B$192M$2.9B
Enterprise ValueMkt cap + debt − cash$36M$675M$6.0B$560M$5.1B
Trailing P/EPrice ÷ TTM EPS-1.91x4.57x-12.14x4.15x8.38x
Forward P/EPrice ÷ next-FY EPS est.5.96x6.50x8.05x
PEG RatioP/E ÷ EPS growth rate4.50x0.17x
EV / EBITDAEnterprise value multiple8.91x14.08x
Price / SalesMarket cap ÷ Revenue2.33x4.81x5.30x
Price / BookPrice ÷ Book value/share5.36x0.63x7.19x0.58x1.36x
Price / FCFMarket cap ÷ FCF3.40x
TPVG leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

HTGC leads this category, winning 4 of 9 comparable metrics.

HTGC delivers a 13.2% return on equity — every $100 of shareholder capital generates $13 in annual profit, vs $-4 for ACTU. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to HRZN's 1.49x. On the Piotroski fundamental quality scale (0–9), HRZN scores 5/9 vs IMVT's 2/9, reflecting solid financial health.

MetricACTU logoACTUActuate Therapeut…TPVG logoTPVGTriplePoint Ventu…IMVT logoIMVTImmunovant, Inc.HRZN logoHRZNHorizon Technolog…HTGC logoHTGCHercules Capital,…
ROE (TTM)Return on equity-4.3%-3.4%-68.2%+9.0%+13.2%
ROA (TTM)Return on assets-180.9%-1.5%-62.2%+3.6%+6.4%
ROICReturn on invested capital+7.2%-0.2%+6.6%
ROCEReturn on capital employed-5.1%+9.4%-68.3%-0.2%+8.8%
Piotroski ScoreFundamental quality 0–944255
Debt / EquityFinancial leverage0.05x1.33x0.00x1.49x1.04x
Net DebtTotal debt minus cash-$13M$449M-$902M$368M$2.2B
Cash & Equiv.Liquid assets$13M$20M$902M$106M$57M
Total DebtShort + long-term debt$404,991$469M$72,000$473M$2.3B
Interest CoverageEBIT ÷ Interest expense-1073.65x-1.02x0.60x4.34x
HTGC leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $2,346 for ACTU. Over the past 12 months, IMVT leads with a +110.9% total return vs ACTU's -76.5%. The 3-year compound annual growth rate (CAGR) favors IMVT at 15.7% vs ACTU's -38.3% — a key indicator of consistent wealth creation.

MetricACTU logoACTUActuate Therapeut…TPVG logoTPVGTriplePoint Ventu…IMVT logoIMVTImmunovant, Inc.HRZN logoHRZNHorizon Technolog…HTGC logoHTGCHercules Capital,…
YTD ReturnYear-to-date-66.5%-12.7%+29.8%-28.1%-12.8%
1-Year ReturnPast 12 months-76.5%-10.7%+110.9%-26.7%-3.6%
3-Year ReturnCumulative with dividends-76.5%-22.4%+55.0%-31.5%+43.9%
5-Year ReturnCumulative with dividends-76.5%-23.3%+213.0%-39.3%+44.7%
10-Year ReturnCumulative with dividends-76.5%+85.3%+237.9%+43.1%+164.1%
CAGR (3Y)Annualised 3-year return-38.3%-8.1%+15.7%-11.8%+12.9%
IMVT leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IMVT and HTGC each lead in 1 of 2 comparable metrics.

HTGC is the less volatile stock with a 0.64 beta — it tends to amplify market swings less than ACTU's 2.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 92.7% from its 52-week high vs ACTU's 21.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricACTU logoACTUActuate Therapeut…TPVG logoTPVGTriplePoint Ventu…IMVT logoIMVTImmunovant, Inc.HRZN logoHRZNHorizon Technolog…HTGC logoHTGCHercules Capital,…
Beta (5Y)Sensitivity to S&P 5002.21x0.65x1.66x0.85x0.64x
52-Week HighHighest price in past year$9.25$7.50$36.27$8.46$19.67
52-Week LowLowest price in past year$1.60$4.48$14.32$3.80$13.70
% of 52W HighCurrent price vs 52-week peak+21.8%+74.3%+92.7%+51.5%+78.8%
RSI (14)Momentum oscillator 0–10039.049.957.956.949.7
Avg Volume (50D)Average daily shares traded178K298K1.9M918K1.7M
Evenly matched — IMVT and HTGC each lead in 1 of 2 comparable metrics.

Analyst Outlook

HRZN leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ACTU as "Buy", TPVG as "Hold", IMVT as "Buy", HRZN as "Hold", HTGC as "Buy". Consensus price targets imply 939.6% upside for ACTU (target: $21) vs -2.5% for HRZN (target: $4). For income investors, HRZN offers the higher dividend yield at 28.76% vs HTGC's 9.14%.

MetricACTU logoACTUActuate Therapeut…TPVG logoTPVGTriplePoint Ventu…IMVT logoIMVTImmunovant, Inc.HRZN logoHRZNHorizon Technolog…HTGC logoHTGCHercules Capital,…
Analyst RatingConsensus buy/hold/sellBuyHoldBuyHoldBuy
Price TargetConsensus 12-month target$21.00$8.95$43.67$4.25$17.58
# AnalystsCovering analysts112232231
Dividend YieldAnnual dividend ÷ price+18.4%+28.8%+9.1%
Dividend StreakConsecutive years of raises010
Dividend / ShareAnnual DPS$1.02$1.25$1.42
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+0.2%
HRZN leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

HTGC leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). TPVG leads in 1 (Valuation Metrics). 1 tied.

Best OverallHercules Capital, Inc. (HTGC)Leads 2 of 6 categories
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ACTU vs TPVG vs IMVT vs HRZN vs HTGC: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ACTU or TPVG or IMVT or HRZN or HTGC a better buy right now?

For growth investors, TriplePoint Venture Growth BDC Corp.

(TPVG) is the stronger pick with 36. 6% revenue growth year-over-year, versus 17. 9% for Horizon Technology Finance Corporation (HRZN). Horizon Technology Finance Corporation (HRZN) offers the better valuation at 4. 2x trailing P/E (6. 5x forward), making it the more compelling value choice. Analysts rate Actuate Therapeutics Inc (ACTU) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ACTU or TPVG or IMVT or HRZN or HTGC?

On trailing P/E, Horizon Technology Finance Corporation (HRZN) is the cheapest at 4.

2x versus Hercules Capital, Inc. at 8. 4x. On forward P/E, TriplePoint Venture Growth BDC Corp. is actually cheaper at 6. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Horizon Technology Finance Corporation wins at 0. 27x versus TriplePoint Venture Growth BDC Corp. 's 5. 88x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — ACTU or TPVG or IMVT or HRZN or HTGC?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -76. 5% for Actuate Therapeutics Inc (ACTU). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus ACTU's -76. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ACTU or TPVG or IMVT or HRZN or HTGC?

By beta (market sensitivity over 5 years), Hercules Capital, Inc.

(HTGC) is the lower-risk stock at 0. 64β versus Actuate Therapeutics Inc's 2. 21β — meaning ACTU is approximately 245% more volatile than HTGC relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 149% for Horizon Technology Finance Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — ACTU or TPVG or IMVT or HRZN or HTGC?

By revenue growth (latest reported year), TriplePoint Venture Growth BDC Corp.

(TPVG) is pulling ahead at 36. 6% versus 17. 9% for Horizon Technology Finance Corporation (HRZN). On earnings-per-share growth, the picture is similar: Horizon Technology Finance Corporation grew EPS 756. 3% year-over-year, compared to -1. 5% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ACTU or TPVG or IMVT or HRZN or HTGC?

Hercules Capital, Inc.

(HTGC) is the more profitable company, earning 62. 1% net margin versus -6. 6% for Horizon Technology Finance Corporation — meaning it keeps 62. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TPVG leads at 77. 9% versus -4. 0% for HRZN. At the gross margin level — before operating expenses — HTGC leads at 87. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ACTU or TPVG or IMVT or HRZN or HTGC more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Horizon Technology Finance Corporation (HRZN) is the more undervalued stock at a PEG of 0. 27x versus TriplePoint Venture Growth BDC Corp. 's 5. 88x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, TriplePoint Venture Growth BDC Corp. (TPVG) trades at 6. 0x forward P/E versus 8. 1x for Hercules Capital, Inc. — 2. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ACTU: 939. 6% to $21. 00.

08

Which pays a better dividend — ACTU or TPVG or IMVT or HRZN or HTGC?

In this comparison, HRZN (28.

8% yield), TPVG (18. 4% yield), HTGC (9. 1% yield) pay a dividend. ACTU, IMVT do not pay a meaningful dividend and should not be held primarily for income.

09

Is ACTU or TPVG or IMVT or HRZN or HTGC better for a retirement portfolio?

For long-horizon retirement investors, Hercules Capital, Inc.

(HTGC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 64), 9. 1% yield, +164. 1% 10Y return). Actuate Therapeutics Inc (ACTU) carries a higher beta of 2. 21 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HTGC: +164. 1%, ACTU: -76. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ACTU and TPVG and IMVT and HRZN and HTGC?

These companies operate in different sectors (ACTU (Healthcare) and TPVG (Financial Services) and IMVT (Healthcare) and HRZN (Financial Services) and HTGC (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ACTU is a small-cap quality compounder stock; TPVG is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; HRZN is a small-cap high-growth stock; HTGC is a small-cap high-growth stock. TPVG, HRZN, HTGC pay a dividend while ACTU, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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