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ADMA vs PRPH vs BIO vs GRFS vs TECH

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ADMA
ADMA Biologics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.89B
5Y Perf.+148.3%
PRPH
ProPhase Labs, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$6M
5Y Perf.-95.8%
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.87B
5Y Perf.-48.2%
GRFS
Grifols, S.A.

Drug Manufacturers - General

HealthcareNASDAQ • ES
Market Cap$6.85B
5Y Perf.-57.2%
TECH
Bio-Techne Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.57B
5Y Perf.-26.9%

ADMA vs PRPH vs BIO vs GRFS vs TECH — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ADMA logoADMA
PRPH logoPRPH
BIO logoBIO
GRFS logoGRFS
TECH logoTECH
IndustryBiotechnologyDrug Manufacturers - Specialty & GenericMedical - DevicesDrug Manufacturers - GeneralBiotechnology
Market Cap$1.89B$6M$6.87B$6.85B$7.57B
Revenue (TTM)$510M$1M$2.59B$7.51B$1.21B
Net Income (TTM)$165M$-42M$169M$401M$110M
Gross Margin61.3%191.4%51.9%38.4%65.0%
Operating Margin42.1%-25.0%9.2%17.0%12.7%
Forward P/E9.7x27.4x9.4x24.9x
Total Debt$80M$25M$1.53B$8.74B$444M
Cash & Equiv.$88M$678K$532M$825M$162M

ADMA vs PRPH vs BIO vs GRFS vs TECHLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ADMA
PRPH
BIO
GRFS
TECH
StockMay 20May 26Return
ADMA Biologics, Inc. (ADMA)100248.3+148.3%
ProPhase Labs, Inc. (PRPH)1004.2-95.8%
Bio-Rad Laboratorie… (BIO)10051.8-48.2%
Grifols, S.A. (GRFS)10042.8-57.2%
Bio-Techne Corporat… (TECH)10073.1-26.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: ADMA vs PRPH vs BIO vs GRFS vs TECH

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ADMA and GRFS are tied at the top with 3 categories each (5-stock set) — the right choice depends on your priorities. Grifols, S.A. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. BIO also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
ADMA
ADMA Biologics, Inc.
The Growth Play

ADMA carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 19.6%, EPS growth -25.9%, 3Y rev CAGR 49.0%
  • 19.6% revenue growth vs PRPH's -84.7%
  • 32.4% margin vs PRPH's -38.7%
  • 27.4% ROA vs PRPH's -63.5%, ROIC 36.0% vs -59.4%
Best for: growth exposure
PRPH
ProPhase Labs, Inc.
The Healthcare Pick

PRPH lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
BIO
Bio-Rad Laboratories, Inc.
The Defensive Pick

BIO ranks third and is worth considering specifically for sleep-well-at-night.

  • Lower volatility, beta 0.91, Low D/E 20.5%, current ratio 5.62x
  • Beta 0.91 vs PRPH's 2.27, lower leverage
Best for: sleep-well-at-night
GRFS
Grifols, S.A.
The Income Pick

GRFS is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.

  • Dividend streak 2 yrs, beta 1.10, yield 2.6%
  • Beta 1.10, yield 2.6%, current ratio 2.51x
  • Lower P/E (9.4x vs 24.9x)
  • 2.6% yield, 2-year raise streak, vs TECH's 0.7%, (3 stocks pay no dividend)
Best for: income & stability and defensive
TECH
Bio-Techne Corporation
The Long-Run Compounder

TECH is the clearest fit if your priority is long-term compounding.

  • 102.6% 10Y total return vs ADMA's 34.8%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthADMA logoADMA19.6% revenue growth vs PRPH's -84.7%
ValueGRFS logoGRFSLower P/E (9.4x vs 24.9x)
Quality / MarginsADMA logoADMA32.4% margin vs PRPH's -38.7%
Stability / SafetyBIO logoBIOBeta 0.91 vs PRPH's 2.27, lower leverage
DividendsGRFS logoGRFS2.6% yield, 2-year raise streak, vs TECH's 0.7%, (3 stocks pay no dividend)
Momentum (1Y)GRFS logoGRFS+13.4% vs ADMA's -61.5%
Efficiency (ROA)ADMA logoADMA27.4% ROA vs PRPH's -63.5%, ROIC 36.0% vs -59.4%

ADMA vs PRPH vs BIO vs GRFS vs TECH — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ADMAADMA Biologics, Inc.
FY 2024
ADMA BioManufacturing Segment
97.4%$416M
Plasma Collection Centers Segment
2.6%$11M
PRPHProPhase Labs, Inc.
FY 2024
Consumer Products
100.0%$7M
BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B
GRFSGrifols, S.A.
FY 2025
Haemoderivatives
86.2%$6.5B
Transfusional medicine
8.3%$623M
Other Product
3.2%$243M
Bio supplies
2.0%$154M
Other diagnostic
0.2%$17M
TECHBio-Techne Corporation
FY 2025
Consumables
87.7%$972M
Instruments
10.1%$112M
Royalty
2.1%$24M

ADMA vs PRPH vs BIO vs GRFS vs TECH — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLADMALAGGINGTECH

Income & Cash Flow (Last 12 Months)

Evenly matched — ADMA and TECH each lead in 2 of 6 comparable metrics.

GRFS is the larger business by revenue, generating $7.5B annually — 6968.8x PRPH's $1M. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to PRPH's -38.7%. On growth, BIO holds the edge at +1.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricADMA logoADMAADMA Biologics, I…PRPH logoPRPHProPhase Labs, In…BIO logoBIOBio-Rad Laborator…GRFS logoGRFSGrifols, S.A.TECH logoTECHBio-Techne Corpor…
RevenueTrailing 12 months$510M$1M$2.6B$7.5B$1.2B
EBITDAEarnings before interest/tax$221M-$22M-$315M$1.6B$254M
Net IncomeAfter-tax profit$165M-$42M$169M$401M$110M
Free Cash FlowCash after capex$108M-$23M$357M$772M$270M
Gross MarginGross profit ÷ Revenue+61.3%+191.4%+51.9%+38.4%+65.0%
Operating MarginEBIT ÷ Revenue+42.1%-25.0%+9.2%+17.0%+12.7%
Net MarginNet income ÷ Revenue+32.4%-38.7%+6.5%+5.3%+9.0%
FCF MarginFCF ÷ Revenue+21.2%-21.1%+13.8%+10.3%+22.3%
Rev. Growth (YoY)Latest quarter vs prior year-0.3%-71.9%+1.1%-0.6%-1.5%
EPS Growth (YoY)Latest quarter vs prior year+72.7%+54.3%-9.5%+40.0%+128.6%
Evenly matched — ADMA and TECH each lead in 2 of 6 comparable metrics.

Valuation Metrics

GRFS leads this category, winning 4 of 6 comparable metrics.

At 9.1x trailing earnings, BIO trades at a 91% valuation discount to TECH's 105.2x P/E. On an enterprise value basis, GRFS's 8.5x EV/EBITDA is more attractive than TECH's 37.0x.

MetricADMA logoADMAADMA Biologics, I…PRPH logoPRPHProPhase Labs, In…BIO logoBIOBio-Rad Laborator…GRFS logoGRFSGrifols, S.A.TECH logoTECHBio-Techne Corpor…
Market CapShares × price$1.9B$6M$6.9B$6.9B$7.6B
Enterprise ValueMkt cap + debt − cash$1.9B$30M$7.9B$16.1B$7.9B
Trailing P/EPrice ÷ TTM EPS13.62x-0.05x9.13x12.11x105.15x
Forward P/EPrice ÷ next-FY EPS est.9.69x27.40x9.35x24.94x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple9.45x16.53x8.49x37.02x
Price / SalesMarket cap ÷ Revenue3.71x0.83x2.66x0.81x6.21x
Price / BookPrice ÷ Book value/share4.19x0.35x0.93x0.62x4.03x
Price / FCFMarket cap ÷ FCF68.06x18.33x7.77x29.52x
GRFS leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

ADMA leads this category, winning 7 of 9 comparable metrics.

ADMA delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $-6 for PRPH. ADMA carries lower financial leverage with a 0.17x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRPH's 3.34x. On the Piotroski fundamental quality scale (0–9), GRFS scores 6/9 vs PRPH's 1/9, reflecting solid financial health.

MetricADMA logoADMAADMA Biologics, I…PRPH logoPRPHProPhase Labs, In…BIO logoBIOBio-Rad Laborator…GRFS logoGRFSGrifols, S.A.TECH logoTECHBio-Techne Corpor…
ROE (TTM)Return on equity+39.0%-6.1%+2.4%+5.2%+5.5%
ROA (TTM)Return on assets+27.4%-63.5%+2.2%+2.0%+4.3%
ROICReturn on invested capital+36.0%-59.4%+2.6%+5.4%+3.4%
ROCEReturn on capital employed+38.8%-75.6%+2.9%+6.4%+4.2%
Piotroski ScoreFundamental quality 0–951565
Debt / EquityFinancial leverage0.17x3.34x0.21x1.15x0.23x
Net DebtTotal debt minus cash-$8M$24M$999M$7.9B$282M
Cash & Equiv.Liquid assets$88M$678,000$532M$825M$162M
Total DebtShort + long-term debt$80M$25M$1.5B$8.7B$444M
Interest CoverageEBIT ÷ Interest expense50.85x-7.96x-2.49x2.05x15.11x
ADMA leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ADMA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ADMA five years ago would be worth $48,922 today (with dividends reinvested), compared to $3,644 for PRPH. Over the past 12 months, GRFS leads with a +13.4% total return vs ADMA's -61.5%. The 3-year compound annual growth rate (CAGR) favors ADMA at 32.7% vs PRPH's -68.2% — a key indicator of consistent wealth creation.

MetricADMA logoADMAADMA Biologics, I…PRPH logoPRPHProPhase Labs, In…BIO logoBIOBio-Rad Laborator…GRFS logoGRFSGrifols, S.A.TECH logoTECHBio-Techne Corpor…
YTD ReturnYear-to-date-54.3%-62.5%-16.7%-12.3%-18.8%
1-Year ReturnPast 12 months-61.5%-55.6%+5.5%+13.4%-2.2%
3-Year ReturnCumulative with dividends+133.4%-96.8%-32.8%+9.5%-40.0%
5-Year ReturnCumulative with dividends+389.2%-63.6%-57.9%-53.6%-51.0%
10-Year ReturnCumulative with dividends+34.8%+38.1%+79.3%-35.2%+102.6%
CAGR (3Y)Annualised 3-year return+32.7%-68.2%-12.4%+3.1%-15.7%
ADMA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

BIO leads this category, winning 2 of 2 comparable metrics.

BIO is the less volatile stock with a 0.91 beta — it tends to amplify market swings less than PRPH's 2.27 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIO currently trades 74.1% from its 52-week high vs PRPH's 7.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricADMA logoADMAADMA Biologics, I…PRPH logoPRPHProPhase Labs, In…BIO logoBIOBio-Rad Laborator…GRFS logoGRFSGrifols, S.A.TECH logoTECHBio-Techne Corpor…
Beta (5Y)Sensitivity to S&P 5001.25x2.27x0.91x1.10x1.20x
52-Week HighHighest price in past year$22.73$1.84$343.12$11.14$72.16
52-Week LowLowest price in past year$7.21$0.07$211.43$7.09$45.12
% of 52W HighCurrent price vs 52-week peak+35.9%+7.3%+74.1%+72.7%+67.0%
RSI (14)Momentum oscillator 0–10026.050.336.145.443.2
Avg Volume (50D)Average daily shares traded7.4M104K304K681K2.4M
BIO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — GRFS and TECH each lead in 1 of 2 comparable metrics.

Analyst consensus: ADMA as "Buy", BIO as "Buy", GRFS as "Buy", TECH as "Buy". Consensus price targets imply 157.0% upside for ADMA (target: $21) vs 22.9% for BIO (target: $313). For income investors, GRFS offers the higher dividend yield at 2.62% vs TECH's 0.65%.

MetricADMA logoADMAADMA Biologics, I…PRPH logoPRPHProPhase Labs, In…BIO logoBIOBio-Rad Laborator…GRFS logoGRFSGrifols, S.A.TECH logoTECHBio-Techne Corpor…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$21.00$312.50$61.33
# AnalystsCovering analysts1014825
Dividend YieldAnnual dividend ÷ price+2.6%+0.7%
Dividend StreakConsecutive years of raises1123
Dividend / ShareAnnual DPS$0.18$0.32
Buyback YieldShare repurchases ÷ mkt cap+1.7%0.0%+4.3%+2.1%+3.6%
Evenly matched — GRFS and TECH each lead in 1 of 2 comparable metrics.
Key Takeaway

ADMA leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). GRFS leads in 1 (Valuation Metrics). 2 tied.

Best OverallADMA Biologics, Inc. (ADMA)Leads 2 of 6 categories
Loading custom metrics...

ADMA vs PRPH vs BIO vs GRFS vs TECH: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ADMA or PRPH or BIO or GRFS or TECH a better buy right now?

For growth investors, ADMA Biologics, Inc.

(ADMA) is the stronger pick with 19. 6% revenue growth year-over-year, versus -84. 7% for ProPhase Labs, Inc. (PRPH). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 1x trailing P/E (27. 4x forward), making it the more compelling value choice. Analysts rate ADMA Biologics, Inc. (ADMA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ADMA or PRPH or BIO or GRFS or TECH?

On trailing P/E, Bio-Rad Laboratories, Inc.

(BIO) is the cheapest at 9. 1x versus Bio-Techne Corporation at 105. 2x. On forward P/E, Grifols, S. A. is actually cheaper at 9. 4x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — ADMA or PRPH or BIO or GRFS or TECH?

Over the past 5 years, ADMA Biologics, Inc.

(ADMA) delivered a total return of +389. 2%, compared to -63. 6% for ProPhase Labs, Inc. (PRPH). Over 10 years, the gap is even starker: TECH returned +102. 6% versus GRFS's -35. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ADMA or PRPH or BIO or GRFS or TECH?

By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.

(BIO) is the lower-risk stock at 0. 91β versus ProPhase Labs, Inc. 's 2. 27β — meaning PRPH is approximately 149% more volatile than BIO relative to the S&P 500. On balance sheet safety, ADMA Biologics, Inc. (ADMA) carries a lower debt/equity ratio of 17% versus 3% for ProPhase Labs, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ADMA or PRPH or BIO or GRFS or TECH?

By revenue growth (latest reported year), ADMA Biologics, Inc.

(ADMA) is pulling ahead at 19. 6% versus -84. 7% for ProPhase Labs, Inc. (PRPH). On earnings-per-share growth, the picture is similar: Grifols, S. A. grew EPS 147. 8% year-over-year, compared to -166. 3% for ProPhase Labs, Inc.. Over a 3-year CAGR, ADMA leads at 49. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ADMA or PRPH or BIO or GRFS or TECH?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus -788. 2% for ProPhase Labs, Inc. — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 37. 5% versus -570. 6% for PRPH. At the gross margin level — before operating expenses — TECH leads at 64. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ADMA or PRPH or BIO or GRFS or TECH more undervalued right now?

On forward earnings alone, Grifols, S.

A. (GRFS) trades at 9. 4x forward P/E versus 27. 4x for Bio-Rad Laboratories, Inc. — 18. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 157. 0% to $21. 00.

08

Which pays a better dividend — ADMA or PRPH or BIO or GRFS or TECH?

In this comparison, GRFS (2.

6% yield), TECH (0. 7% yield) pay a dividend. ADMA, PRPH, BIO do not pay a meaningful dividend and should not be held primarily for income.

09

Is ADMA or PRPH or BIO or GRFS or TECH better for a retirement portfolio?

For long-horizon retirement investors, Bio-Techne Corporation (TECH) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.

20), 0. 7% yield, +102. 6% 10Y return). ProPhase Labs, Inc. (PRPH) carries a higher beta of 2. 27 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (TECH: +102. 6%, PRPH: +38. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ADMA and PRPH and BIO and GRFS and TECH?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ADMA is a small-cap high-growth stock; PRPH is a small-cap quality compounder stock; BIO is a small-cap deep-value stock; GRFS is a small-cap deep-value stock; TECH is a small-cap quality compounder stock. GRFS, TECH pay a dividend while ADMA, PRPH, BIO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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ADMA

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 19%
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  • Market Cap > $100B
  • Gross Margin > 114%
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BIO

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  • Market Cap > $100B
  • Net Margin > 5%
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Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 5%
  • Dividend Yield > 1.0%
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Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
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(ADMA: -0.3% · PRPH: -71.9%)

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