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ADXN vs INVA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ADXN
Addex Therapeutics Ltd

Biotechnology

HealthcareNASDAQ • CH
Market Cap$5M
5Y Perf.-95.2%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.93B
5Y Perf.+63.2%

ADXN vs INVA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ADXN logoADXN
INVA logoINVA
IndustryBiotechnologyBiotechnology
Market Cap$5M$1.93B
Revenue (TTM)$68K$424M
Net Income (TTM)$-6M$504M
Gross Margin-246.8%76.2%
Operating Margin-36.7%14.8%
Forward P/E0.7x11.9x
Total Debt$42K$269M
Cash & Equiv.$3M$551M

ADXN vs INVALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ADXN
INVA
StockMay 20May 26Return
Addex Therapeutics … (ADXN)1004.8-95.2%
Innoviva, Inc. (INVA)100163.2+63.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: ADXN vs INVA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 5 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Addex Therapeutics Ltd is the stronger pick specifically for valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
ADXN
Addex Therapeutics Ltd
The Value Play

ADXN is the clearest fit if your priority is value.

  • Lower P/E (0.7x vs 11.9x)
Best for: value
INVA
Innoviva, Inc.
The Income Pick

INVA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 0 yrs, beta 0.13
  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • 94.9% 10Y total return vs ADXN's -96.9%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthINVA logoINVA18.5% revenue growth vs ADXN's -74.9%
ValueADXN logoADXNLower P/E (0.7x vs 11.9x)
Quality / MarginsINVA logoINVA118.9% margin vs ADXN's -90.2%
Stability / SafetyINVA logoINVABeta 0.13 vs ADXN's 0.59
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)INVA logoINVA+21.7% vs ADXN's -13.1%
Efficiency (ROA)INVA logoINVA32.4% ROA vs ADXN's -67.7%, ROIC 14.2% vs -103.3%

ADXN vs INVA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ADXNAddex Therapeutics Ltd
FY 2024
Research
100.0%$400,000
INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M

ADXN vs INVA — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGADXN

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 6 of 6 comparable metrics.

INVA is the larger business by revenue, generating $424M annually — 6273.3x ADXN's $67,607. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to ADXN's -90.2%. On growth, INVA holds the edge at +10.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricADXN logoADXNAddex Therapeutic…INVA logoINVAInnoviva, Inc.
RevenueTrailing 12 months$67,607$424M
EBITDAEarnings before interest/tax-$2M$86M
Net IncomeAfter-tax profit-$6M$504M
Free Cash FlowCash after capex-$2M$181M
Gross MarginGross profit ÷ Revenue-2.5%+76.2%
Operating MarginEBIT ÷ Revenue-36.7%+14.8%
Net MarginNet income ÷ Revenue-90.2%+118.9%
FCF MarginFCF ÷ Revenue-23.3%+42.8%
Rev. Growth (YoY)Latest quarter vs prior year-44.8%+10.6%
EPS Growth (YoY)Latest quarter vs prior year+11.2%+4.0%
INVA leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

ADXN leads this category, winning 2 of 3 comparable metrics.

At 0.7x trailing earnings, ADXN trades at a 91% valuation discount to INVA's 6.9x P/E.

MetricADXN logoADXNAddex Therapeutic…INVA logoINVAInnoviva, Inc.
Market CapShares × price$5M$1.9B
Enterprise ValueMkt cap + debt − cash$394,716$1.7B
Trailing P/EPrice ÷ TTM EPS0.65x6.91x
Forward P/EPrice ÷ next-FY EPS est.11.91x
PEG RatioP/E ÷ EPS growth rate0.67x
EV / EBITDAEnterprise value multiple8.10x
Price / SalesMarket cap ÷ Revenue8.93x4.55x
Price / BookPrice ÷ Book value/share0.46x1.65x
Price / FCFMarket cap ÷ FCF9.88x
ADXN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 7 of 9 comparable metrics.

INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-78 for ADXN. ADXN carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to INVA's 0.23x. On the Piotroski fundamental quality scale (0–9), INVA scores 5/9 vs ADXN's 4/9, reflecting solid financial health.

MetricADXN logoADXNAddex Therapeutic…INVA logoINVAInnoviva, Inc.
ROE (TTM)Return on equity-78.3%+46.5%
ROA (TTM)Return on assets-67.7%+32.4%
ROICReturn on invested capital-103.3%+14.2%
ROCEReturn on capital employed-47.4%+12.4%
Piotroski ScoreFundamental quality 0–945
Debt / EquityFinancial leverage0.00x0.23x
Net DebtTotal debt minus cash-$3M-$282M
Cash & Equiv.Liquid assets$3M$551M
Total DebtShort + long-term debt$41,994$269M
Interest CoverageEBIT ÷ Interest expense-1857.72x63.45x
INVA leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INVA leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $354 for ADXN. Over the past 12 months, INVA leads with a +21.7% total return vs ADXN's -13.1%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs ADXN's -21.7% — a key indicator of consistent wealth creation.

MetricADXN logoADXNAddex Therapeutic…INVA logoINVAInnoviva, Inc.
YTD ReturnYear-to-date-13.3%+14.7%
1-Year ReturnPast 12 months-13.1%+21.7%
3-Year ReturnCumulative with dividends-52.0%+95.2%
5-Year ReturnCumulative with dividends-96.5%+94.4%
10-Year ReturnCumulative with dividends-96.9%+94.9%
CAGR (3Y)Annualised 3-year return-21.7%+25.0%
INVA leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

INVA leads this category, winning 2 of 2 comparable metrics.

INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than ADXN's 0.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 90.7% from its 52-week high vs ADXN's 58.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricADXN logoADXNAddex Therapeutic…INVA logoINVAInnoviva, Inc.
Beta (5Y)Sensitivity to S&P 5000.59x0.13x
52-Week HighHighest price in past year$12.05$25.15
52-Week LowLowest price in past year$5.41$16.52
% of 52W HighCurrent price vs 52-week peak+58.2%+90.7%
RSI (14)Momentum oscillator 0–10051.339.9
Avg Volume (50D)Average daily shares traded4K621K
INVA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricADXN logoADXNAddex Therapeutic…INVA logoINVAInnoviva, Inc.
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$37.67
# AnalystsCovering analysts10
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

INVA leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ADXN leads in 1 (Valuation Metrics).

Best OverallInnoviva, Inc. (INVA)Leads 4 of 6 categories
Loading custom metrics...

ADXN vs INVA: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is ADXN or INVA a better buy right now?

For growth investors, Innoviva, Inc.

(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -74. 9% for Addex Therapeutics Ltd (ADXN). Addex Therapeutics Ltd (ADXN) offers the better valuation at 0. 7x trailing P/E, making it the more compelling value choice. Analysts rate Innoviva, Inc. (INVA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ADXN or INVA?

On trailing P/E, Addex Therapeutics Ltd (ADXN) is the cheapest at 0.

7x versus Innoviva, Inc. at 6. 9x.

03

Which is the better long-term investment — ADXN or INVA?

Over the past 5 years, Innoviva, Inc.

(INVA) delivered a total return of +94. 4%, compared to -96. 5% for Addex Therapeutics Ltd (ADXN). Over 10 years, the gap is even starker: INVA returned +94. 9% versus ADXN's -96. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ADXN or INVA?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 13β versus Addex Therapeutics Ltd's 0. 59β — meaning ADXN is approximately 368% more volatile than INVA relative to the S&P 500. On balance sheet safety, Addex Therapeutics Ltd (ADXN) carries a lower debt/equity ratio of 0% versus 23% for Innoviva, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ADXN or INVA?

By revenue growth (latest reported year), Innoviva, Inc.

(INVA) is pulling ahead at 18. 5% versus -74. 9% for Addex Therapeutics Ltd (ADXN). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to 150. 0% for Addex Therapeutics Ltd. Over a 3-year CAGR, INVA leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ADXN or INVA?

Addex Therapeutics Ltd (ADXN) is the more profitable company, earning 1746% net margin versus 63.

8% for Innoviva, Inc. — meaning it keeps 1746% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -681. 8% for ADXN. At the gross margin level — before operating expenses — ADXN leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Which pays a better dividend — ADXN or INVA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is ADXN or INVA better for a retirement portfolio?

For long-horizon retirement investors, Innoviva, Inc.

(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 13)). Both have compounded well over 10 years (INVA: +94. 9%, ADXN: -96. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between ADXN and INVA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ADXN is a small-cap deep-value stock; INVA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Stocks Like

ADXN

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
Run This Screen
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INVA

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 71%
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Beat Both

Find stocks that outperform ADXN and INVA on the metrics below

Revenue Growth>
%
(ADXN: -44.8% · INVA: 10.6%)
P/E Ratio<
x
(ADXN: 0.7x · INVA: 6.9x)

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