Biotechnology
Compare Stocks
2 / 10Stock Comparison
ADXN vs INVA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
ADXN vs INVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $5M | $1.93B |
| Revenue (TTM) | $68K | $424M |
| Net Income (TTM) | $-6M | $504M |
| Gross Margin | -246.8% | 76.2% |
| Operating Margin | -36.7% | 14.8% |
| Forward P/E | 0.7x | 11.9x |
| Total Debt | $42K | $269M |
| Cash & Equiv. | $3M | $551M |
ADXN vs INVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Addex Therapeutics … (ADXN) | 100 | 4.8 | -95.2% |
| Innoviva, Inc. (INVA) | 100 | 163.2 | +63.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ADXN vs INVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ADXN is the clearest fit if your priority is value.
- Lower P/E (0.7x vs 11.9x)
INVA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 0.13
- Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
- 94.9% 10Y total return vs ADXN's -96.9%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 18.5% revenue growth vs ADXN's -74.9% | |
| Value | Lower P/E (0.7x vs 11.9x) | |
| Quality / Margins | 118.9% margin vs ADXN's -90.2% | |
| Stability / Safety | Beta 0.13 vs ADXN's 0.59 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +21.7% vs ADXN's -13.1% | |
| Efficiency (ROA) | 32.4% ROA vs ADXN's -67.7%, ROIC 14.2% vs -103.3% |
ADXN vs INVA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
ADXN vs INVA — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
INVA leads this category, winning 6 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
INVA is the larger business by revenue, generating $424M annually — 6273.3x ADXN's $67,607. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to ADXN's -90.2%. On growth, INVA holds the edge at +10.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $67,607 | $424M |
| EBITDAEarnings before interest/tax | -$2M | $86M |
| Net IncomeAfter-tax profit | -$6M | $504M |
| Free Cash FlowCash after capex | -$2M | $181M |
| Gross MarginGross profit ÷ Revenue | -2.5% | +76.2% |
| Operating MarginEBIT ÷ Revenue | -36.7% | +14.8% |
| Net MarginNet income ÷ Revenue | -90.2% | +118.9% |
| FCF MarginFCF ÷ Revenue | -23.3% | +42.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -44.8% | +10.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +11.2% | +4.0% |
Valuation Metrics
ADXN leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
At 0.7x trailing earnings, ADXN trades at a 91% valuation discount to INVA's 6.9x P/E.
| Metric | ||
|---|---|---|
| Market CapShares × price | $5M | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $394,716 | $1.7B |
| Trailing P/EPrice ÷ TTM EPS | 0.65x | 6.91x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 11.91x |
| PEG RatioP/E ÷ EPS growth rate | — | 0.67x |
| EV / EBITDAEnterprise value multiple | — | 8.10x |
| Price / SalesMarket cap ÷ Revenue | 8.93x | 4.55x |
| Price / BookPrice ÷ Book value/share | 0.46x | 1.65x |
| Price / FCFMarket cap ÷ FCF | — | 9.88x |
Profitability & Efficiency
INVA leads this category, winning 7 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-78 for ADXN. ADXN carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to INVA's 0.23x. On the Piotroski fundamental quality scale (0–9), INVA scores 5/9 vs ADXN's 4/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -78.3% | +46.5% |
| ROA (TTM)Return on assets | -67.7% | +32.4% |
| ROICReturn on invested capital | -103.3% | +14.2% |
| ROCEReturn on capital employed | -47.4% | +12.4% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 |
| Debt / EquityFinancial leverage | 0.00x | 0.23x |
| Net DebtTotal debt minus cash | -$3M | -$282M |
| Cash & Equiv.Liquid assets | $3M | $551M |
| Total DebtShort + long-term debt | $41,994 | $269M |
| Interest CoverageEBIT ÷ Interest expense | -1857.72x | 63.45x |
Total Returns (Dividends Reinvested)
INVA leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $354 for ADXN. Over the past 12 months, INVA leads with a +21.7% total return vs ADXN's -13.1%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs ADXN's -21.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -13.3% | +14.7% |
| 1-Year ReturnPast 12 months | -13.1% | +21.7% |
| 3-Year ReturnCumulative with dividends | -52.0% | +95.2% |
| 5-Year ReturnCumulative with dividends | -96.5% | +94.4% |
| 10-Year ReturnCumulative with dividends | -96.9% | +94.9% |
| CAGR (3Y)Annualised 3-year return | -21.7% | +25.0% |
Risk & Volatility
INVA leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than ADXN's 0.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 90.7% from its 52-week high vs ADXN's 58.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.59x | 0.13x |
| 52-Week HighHighest price in past year | $12.05 | $25.15 |
| 52-Week LowLowest price in past year | $5.41 | $16.52 |
| % of 52W HighCurrent price vs 52-week peak | +58.2% | +90.7% |
| RSI (14)Momentum oscillator 0–100 | 51.3 | 39.9 |
| Avg Volume (50D)Average daily shares traded | 4K | 621K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $37.67 |
| # AnalystsCovering analysts | — | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | 0 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.2% |
INVA leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ADXN leads in 1 (Valuation Metrics).
ADXN vs INVA: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is ADXN or INVA a better buy right now?
For growth investors, Innoviva, Inc.
(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -74. 9% for Addex Therapeutics Ltd (ADXN). Addex Therapeutics Ltd (ADXN) offers the better valuation at 0. 7x trailing P/E, making it the more compelling value choice. Analysts rate Innoviva, Inc. (INVA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ADXN or INVA?
On trailing P/E, Addex Therapeutics Ltd (ADXN) is the cheapest at 0.
7x versus Innoviva, Inc. at 6. 9x.
03Which is the better long-term investment — ADXN or INVA?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 4%, compared to -96. 5% for Addex Therapeutics Ltd (ADXN). Over 10 years, the gap is even starker: INVA returned +94. 9% versus ADXN's -96. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ADXN or INVA?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus Addex Therapeutics Ltd's 0. 59β — meaning ADXN is approximately 368% more volatile than INVA relative to the S&P 500. On balance sheet safety, Addex Therapeutics Ltd (ADXN) carries a lower debt/equity ratio of 0% versus 23% for Innoviva, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ADXN or INVA?
By revenue growth (latest reported year), Innoviva, Inc.
(INVA) is pulling ahead at 18. 5% versus -74. 9% for Addex Therapeutics Ltd (ADXN). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to 150. 0% for Addex Therapeutics Ltd. Over a 3-year CAGR, INVA leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ADXN or INVA?
Addex Therapeutics Ltd (ADXN) is the more profitable company, earning 1746% net margin versus 63.
8% for Innoviva, Inc. — meaning it keeps 1746% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -681. 8% for ADXN. At the gross margin level — before operating expenses — ADXN leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Which pays a better dividend — ADXN or INVA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is ADXN or INVA better for a retirement portfolio?
For long-horizon retirement investors, Innoviva, Inc.
(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 13)). Both have compounded well over 10 years (INVA: +94. 9%, ADXN: -96. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ADXN and INVA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ADXN is a small-cap deep-value stock; INVA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.