Biotechnology
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Side-by-side financial analysisStock Comparison
AEON vs ABBV vs KO vs IQV vs CRL
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Beverages - Non-Alcoholic
Medical - Diagnostics & Research
Medical - Diagnostics & Research
AEON vs ABBV vs KO vs IQV vs CRL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Beverages - Non-Alcoholic | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $9M | $402.80B | $355.61B | $30.79B | $9.03B |
| Revenue (TTM) | $0.00 | $61.16B | $49.28B | $16.63B | $4.03B |
| Net Income (TTM) | $-60M | $4.23B | $13.70B | $1.39B | $-185M |
| Gross Margin | — | 70.2% | 61.7% | 26.1% | 31.9% |
| Operating Margin | — | 26.7% | 29.3% | 13.9% | 11.8% |
| Forward P/E | — | 16.0x | 25.3x | 14.2x | 16.9x |
| Total Debt | $36M | $69.07B | $45.49B | $16.17B | $3.07B |
| Cash & Equiv. | $3M | $5.23B | $10.27B | $1.98B | $214M |
AEON vs ABBV vs KO vs IQV vs CRL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 23 | Jun 26 | Return |
|---|---|---|---|
| AEON Biopharma, Inc. (AEON) | 100 | 0.1 | -99.9% |
| AbbVie Inc. (ABBV) | 100 | 152.2 | +52.2% |
| The Coca-Cola Compa… (KO) | 100 | 133.4 | +33.4% |
| IQVIA Holdings Inc. (IQV) | 100 | 81.1 | -18.9% |
| Charles River Labor… (CRL) | 100 | 89.5 | -10.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AEON vs ABBV vs KO vs IQV vs CRL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AEON ranks third and is worth considering specifically for stability.
- Beta 0.11 vs CRL's 1.39
ABBV has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.
- Dividend streak 43 yrs, beta 0.14, yield 2.9%
- 362.2% 10Y total return vs IQV's 177.5%
- Beta 0.14, yield 2.9%, current ratio 0.67x
- 8.6% revenue growth vs AEON's -135.5%
KO is the #2 pick in this set and the best alternative if quality and efficiency is your priority.
- 27.8% margin vs CRL's -4.6%
- 13.1% ROA vs AEON's -7.0%
IQV is the clearest fit if your priority is growth exposure and valuation efficiency.
- Rev growth 5.9%, EPS growth 4.7%, 3Y rev CAGR 4.2%
- PEG 0.35 vs KO's 2.26
- Lower P/E (14.2x vs 16.9x)
CRL is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.39, Low D/E 95.5%, current ratio 1.29x
- +23.5% vs AEON's -18.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs AEON's -135.5% | |
| Value | Lower P/E (14.2x vs 16.9x) | |
| Quality / Margins | 27.8% margin vs CRL's -4.6% | |
| Stability / Safety | Beta 0.11 vs CRL's 1.39 | |
| Dividends | 2.9% yield, 43-year raise streak, vs KO's 2.5%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +23.5% vs AEON's -18.1% | |
| Efficiency (ROA) | 13.1% ROA vs AEON's -7.0% |
AEON vs ABBV vs KO vs IQV vs CRL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
AEON vs ABBV vs KO vs IQV vs CRL — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
IQV leads in 1 of 6 categories
ABBV leads 1 • KO leads 1 • AEON leads 0 • CRL leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ABBV and KO each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV and AEON operate at a comparable scale, with $61.2B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to CRL's -4.6%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $61.2B | $49.3B | $16.6B | $4.0B |
| EBITDAEarnings before interest/tax | -$18M | $24.5B | $15.5B | $3.5B | $824M |
| Net IncomeAfter-tax profit | -$60M | $4.2B | $13.7B | $1.4B | -$185M |
| Free Cash FlowCash after capex | -$12M | $18.7B | $12.6B | $2.7B | $391M |
| Gross MarginGross profit ÷ Revenue | — | +70.2% | +61.7% | +26.1% | +31.9% |
| Operating MarginEBIT ÷ Revenue | — | +26.7% | +29.3% | +13.9% | +11.8% |
| Net MarginNet income ÷ Revenue | — | +6.9% | +27.8% | +8.3% | -4.6% |
| FCF MarginFCF ÷ Revenue | — | +30.6% | +25.5% | +16.1% | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +10.0% | +12.1% | +8.4% | +1.2% |
| EPS Growth (YoY)Latest quarter vs prior year | -142.5% | +57.4% | +18.2% | +15.0% | -160.0% |
Valuation Metrics
IQV leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 23.1x trailing earnings, IQV trades at a 76% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.57x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $9M | $402.8B | $355.6B | $30.8B | $9.0B |
| Enterprise ValueMkt cap + debt − cash | $41M | $466.6B | $390.8B | $45.0B | $11.9B |
| Trailing P/EPrice ÷ TTM EPS | -0.18x | 96.09x | 27.18x | 23.15x | -64.44x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 15.96x | 25.27x | 14.16x | 16.90x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.43x | 0.57x | — |
| EV / EBITDAEnterprise value multiple | — | 16.53x | 26.39x | 13.11x | 13.04x |
| Price / SalesMarket cap ÷ Revenue | — | 6.59x | 7.42x | 1.89x | 2.25x |
| Price / BookPrice ÷ Book value/share | — | — | 10.40x | 4.75x | 2.89x |
| Price / FCFMarket cap ÷ FCF | — | 22.61x | 67.15x | 15.01x | 17.42x |
Profitability & Efficiency
Evenly matched — ABBV and KO each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-6 for CRL. CRL carries lower financial leverage with a 0.95x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs AEON's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | +62.1% | +41.1% | +22.1% | -5.7% |
| ROA (TTM)Return on assets | -7.0% | +3.1% | +13.1% | +4.7% | -2.5% |
| ROICReturn on invested capital | — | +23.9% | +15.8% | +8.7% | +6.3% |
| ROCEReturn on capital employed | — | +21.5% | +17.3% | +11.0% | +8.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 6 | 7 | 4 | 4 |
| Debt / EquityFinancial leverage | — | — | 1.33x | 2.44x | 0.95x |
| Net DebtTotal debt minus cash | $33M | $63.8B | $35.2B | $14.2B | $2.9B |
| Cash & Equiv.Liquid assets | $3M | $5.2B | $10.3B | $2.0B | $214M |
| Total DebtShort + long-term debt | $36M | $69.1B | $45.5B | $16.2B | $3.1B |
| Interest CoverageEBIT ÷ Interest expense | — | 3.28x | 10.70x | 3.10x | 4.29x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $22,367 today (with dividends reinvested), compared to $11 for AEON. Over the past 12 months, CRL leads with a +23.5% total return vs AEON's -18.1%. The 3-year compound annual growth rate (CAGR) favors ABBV at 21.5% vs AEON's -89.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -34.2% | +0.8% | +20.3% | -19.5% | -7.4% |
| 1-Year ReturnPast 12 months | -18.1% | +21.9% | +17.2% | +14.0% | +23.5% |
| 3-Year ReturnCumulative with dividends | -99.9% | +79.3% | +47.0% | -14.4% | -8.7% |
| 5-Year ReturnCumulative with dividends | -99.9% | +123.7% | +65.6% | -25.8% | -47.2% |
| 10-Year ReturnCumulative with dividends | -99.9% | +362.2% | +121.1% | +177.5% | +122.4% |
| CAGR (3Y)Annualised 3-year return | -89.7% | +21.5% | +13.7% | -5.0% | -3.0% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than CRL's 1.39 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs AEON's 50.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.11x | 0.14x | -0.20x | 1.16x | 1.39x |
| 52-Week HighHighest price in past year | $1.45 | $244.81 | $84.04 | $247.05 | $228.88 |
| 52-Week LowLowest price in past year | $0.63 | $181.73 | $65.35 | $153.01 | $143.06 |
| % of 52W HighCurrent price vs 52-week peak | +50.4% | +93.0% | +98.3% | +73.5% | +81.9% |
| RSI (14)Momentum oscillator 0–100 | 33.7 | 62.8 | 60.6 | 54.4 | 60.8 |
| Avg Volume (50D)Average daily shares traded | 85K | 4.6M | 12.7M | 1.5M | 767K |
Analyst Outlook
Evenly matched — ABBV and KO each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ABBV as "Buy", KO as "Buy", IQV as "Buy", CRL as "Buy". Consensus price targets imply 22.5% upside for IQV (target: $222) vs 4.2% for KO (target: $86). For income investors, ABBV offers the higher dividend yield at 2.89% vs KO's 2.46%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $256.92 | $86.13 | $222.22 | $213.17 |
| # AnalystsCovering analysts | — | 41 | 48 | 44 | 37 |
| Dividend YieldAnnual dividend ÷ price | — | +2.9% | +2.5% | — | — |
| Dividend StreakConsecutive years of raises | — | 43 | 56 | 2 | 1 |
| Dividend / ShareAnnual DPS | — | $6.57 | $2.04 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.2% | +0.2% | +4.0% | +4.0% |
IQV leads in 1 of 6 categories (Valuation Metrics). ABBV leads in 1 (Total Returns). 3 tied.
AEON vs ABBV vs KO vs IQV vs CRL: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is AEON or ABBV or KO or IQV or CRL a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). IQVIA Holdings Inc. (IQV) offers the better valuation at 23. 1x trailing P/E (14. 2x forward), making it the more compelling value choice. Analysts rate AbbVie Inc. (ABBV) a "Buy" — based on 41 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — AEON or ABBV or KO or IQV or CRL?
On trailing P/E, IQVIA Holdings Inc.
(IQV) is the cheapest at 23. 1x versus AbbVie Inc. at 96. 1x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 14. 2x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — AEON or ABBV or KO or IQV or CRL?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +123. 7%, compared to -99. 9% for AEON Biopharma, Inc. (AEON). Over 10 years, the gap is even starker: ABBV returned +362. 2% versus AEON's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — AEON or ABBV or KO or IQV or CRL?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Charles River Laboratories International, Inc. 's 1. 39β — meaning CRL is approximately -792% more volatile than KO relative to the S&P 500. On balance sheet safety, Charles River Laboratories International, Inc. (CRL) carries a lower debt/equity ratio of 95% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — AEON or ABBV or KO or IQV or CRL?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: The Coca-Cola Company grew EPS 23. 6% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, IQV leads at 4. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — AEON or ABBV or KO or IQV or CRL?
The Coca-Cola Company (KO) is the more profitable company, earning 27.
3% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus 0. 0% for AEON. At the gross margin level — before operating expenses — ABBV leads at 70. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is AEON or ABBV or KO or IQV or CRL more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 14. 2x forward P/E versus 25. 3x for The Coca-Cola Company — 11. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IQV: 22. 5% to $222. 22.
08Which pays a better dividend — AEON or ABBV or KO or IQV or CRL?
In this comparison, ABBV (2.
9% yield), KO (2. 5% yield) pay a dividend. AEON, IQV, CRL do not pay a meaningful dividend and should not be held primarily for income.
09Is AEON or ABBV or KO or IQV or CRL better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, CRL: +122. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between AEON and ABBV and KO and IQV and CRL?
These companies operate in different sectors (AEON (Healthcare) and ABBV (Healthcare) and KO (Consumer Defensive) and IQV (Healthcare) and CRL (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
ABBV, KO pay a dividend while AEON, IQV, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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