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ANIK vs JNJ vs SYK vs BSX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ANIK
Anika Therapeutics, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$198M
5Y Perf.-55.9%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$533.36B
5Y Perf.+48.8%
SYK
Stryker Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$109.33B
5Y Perf.+45.8%
BSX
Boston Scientific Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$80.15B
5Y Perf.+42.0%

ANIK vs JNJ vs SYK vs BSX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ANIK logoANIK
JNJ logoJNJ
SYK logoSYK
BSX logoBSX
IndustryMedical - DevicesDrug Manufacturers - GeneralMedical - DevicesMedical - Devices
Market Cap$198M$533.36B$109.33B$80.15B
Revenue (TTM)$116M$92.15B$25.12B$20.07B
Net Income (TTM)$-11M$25.12B$3.25B$2.89B
Gross Margin58.6%68.1%63.5%69.0%
Operating Margin-10.5%26.1%22.4%19.8%
Forward P/E19.1x19.1x16.0x
Total Debt$24M$36.63B$14.86B$12.42B
Cash & Equiv.$57M$24.11B$4.01B$2.04B

ANIK vs JNJ vs SYK vs BSXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ANIK
JNJ
SYK
BSX
StockMay 20May 26Return
Anika Therapeutics,… (ANIK)10044.1-55.9%
Johnson & Johnson (JNJ)100148.8+48.8%
Stryker Corporation (SYK)100145.8+45.8%
Boston Scientific C… (BSX)100142.0+42.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: ANIK vs JNJ vs SYK vs BSX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JNJ leads in 5 of 7 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Boston Scientific Corporation is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
ANIK
Anika Therapeutics, Inc.
The Specific-Use Pick

ANIK plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
JNJ
Johnson & Johnson
The Income Pick

JNJ carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 36 yrs, beta 0.04, yield 2.2%
  • Lower volatility, beta 0.04, Low D/E 51.2%, current ratio 1.11x
  • Beta 0.04, yield 2.2%, current ratio 1.11x
  • 27.3% margin vs ANIK's -9.5%
Best for: income & stability and sleep-well-at-night
SYK
Stryker Corporation
The Long-Run Compounder

SYK is the clearest fit if your priority is long-term compounding and valuation efficiency.

  • 179.2% 10Y total return vs BSX's 143.6%
  • PEG 1.28 vs JNJ's 34.02
Best for: long-term compounding and valuation efficiency
BSX
Boston Scientific Corporation
The Growth Play

BSX is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 19.9%, EPS growth 55.2%, 3Y rev CAGR 16.5%
  • 19.9% revenue growth vs ANIK's -5.9%
  • Lower P/E (16.0x vs 19.1x)
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBSX logoBSX19.9% revenue growth vs ANIK's -5.9%
ValueBSX logoBSXLower P/E (16.0x vs 19.1x)
Quality / MarginsJNJ logoJNJ27.3% margin vs ANIK's -9.5%
Stability / SafetyJNJ logoJNJBeta 0.04 vs ANIK's 1.10
DividendsJNJ logoJNJ2.2% yield, 36-year raise streak, vs SYK's 1.2%, (2 stocks pay no dividend)
Momentum (1Y)JNJ logoJNJ+45.5% vs BSX's -47.8%
Efficiency (ROA)JNJ logoJNJ13.0% ROA vs ANIK's -5.9%, ROIC 20.7% vs -7.1%

ANIK vs JNJ vs SYK vs BSX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ANIKAnika Therapeutics, Inc.
FY 2023
Joint Preservation and Restoration
84.8%$55M
Non-Orthopedic
15.2%$10M
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B
SYKStryker Corporation
FY 2025
MedSurg
62.3%$15.6B
Orthopaedics
37.7%$9.5B
BSXBoston Scientific Corporation
FY 2025
Cardiovascular
66.0%$13.3B
MedSurg
34.0%$6.8B

ANIK vs JNJ vs SYK vs BSX — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJNJLAGGINGBSX

Income & Cash Flow (Last 12 Months)

JNJ leads this category, winning 4 of 6 comparable metrics.

JNJ is the larger business by revenue, generating $92.1B annually — 792.6x ANIK's $116M. JNJ is the more profitable business, keeping 27.3% of every revenue dollar as net income compared to ANIK's -9.5%. On growth, BSX holds the edge at +15.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricANIK logoANIKAnika Therapeutic…JNJ logoJNJJohnson & JohnsonSYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
RevenueTrailing 12 months$116M$92.1B$25.1B$20.1B
EBITDAEarnings before interest/tax-$7M$31.4B$6.3B$4.7B
Net IncomeAfter-tax profit-$11M$25.1B$3.2B$2.9B
Free Cash FlowCash after capex$1M$19.1B$4.3B$3.6B
Gross MarginGross profit ÷ Revenue+58.6%+68.1%+63.5%+69.0%
Operating MarginEBIT ÷ Revenue-10.5%+26.1%+22.4%+19.8%
Net MarginNet income ÷ Revenue-9.5%+27.3%+12.9%+14.4%
FCF MarginFCF ÷ Revenue+0.9%+20.7%+17.1%+18.1%
Rev. Growth (YoY)Latest quarter vs prior year+13.2%+6.8%+11.4%+15.9%
EPS Growth (YoY)Latest quarter vs prior year-8.8%+91.0%+56.0%+18.5%
JNJ leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

ANIK leads this category, winning 3 of 7 comparable metrics.

At 27.8x trailing earnings, BSX trades at a 27% valuation discount to JNJ's 38.2x P/E. Adjusting for growth (PEG ratio), SYK offers better value at 2.29x vs JNJ's 34.02x — a lower PEG means you pay less per unit of expected earnings growth.

MetricANIK logoANIKAnika Therapeutic…JNJ logoJNJJohnson & JohnsonSYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
Market CapShares × price$198M$533.4B$109.3B$80.1B
Enterprise ValueMkt cap + debt − cash$165M$545.9B$120.2B$90.5B
Trailing P/EPrice ÷ TTM EPS-19.43x38.22x33.98x27.80x
Forward P/EPrice ÷ next-FY EPS est.19.12x19.06x15.96x
PEG RatioP/E ÷ EPS growth rate34.02x2.29x
EV / EBITDAEnterprise value multiple18.51x19.76x24.25x
Price / SalesMarket cap ÷ Revenue1.75x6.00x4.35x3.99x
Price / BookPrice ÷ Book value/share1.48x7.52x4.87x3.29x
Price / FCFMarket cap ÷ FCF45.38x26.88x25.53x21.91x
ANIK leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

JNJ leads this category, winning 5 of 9 comparable metrics.

JNJ delivers a 31.7% return on equity — every $100 of shareholder capital generates $32 in annual profit, vs $-8 for ANIK. ANIK carries lower financial leverage with a 0.17x debt-to-equity ratio, signaling a more conservative balance sheet compared to SYK's 0.66x. On the Piotroski fundamental quality scale (0–9), BSX scores 7/9 vs JNJ's 5/9, reflecting strong financial health.

MetricANIK logoANIKAnika Therapeutic…JNJ logoJNJJohnson & JohnsonSYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
ROE (TTM)Return on equity-7.7%+31.7%+15.0%+12.4%
ROA (TTM)Return on assets-5.9%+13.0%+6.9%+6.9%
ROICReturn on invested capital-7.1%+20.7%+11.4%+8.8%
ROCEReturn on capital employed-6.4%+17.6%+13.0%+11.1%
Piotroski ScoreFundamental quality 0–96567
Debt / EquityFinancial leverage0.17x0.51x0.66x0.51x
Net DebtTotal debt minus cash-$33M$12.5B$10.8B$10.4B
Cash & Equiv.Liquid assets$57M$24.1B$4.0B$2.0B
Total DebtShort + long-term debt$24M$36.6B$14.9B$12.4B
Interest CoverageEBIT ÷ Interest expense48.23x6.72x11.03x
JNJ leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JNJ leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in JNJ five years ago would be worth $14,389 today (with dividends reinvested), compared to $3,559 for ANIK. Over the past 12 months, JNJ leads with a +45.5% total return vs BSX's -47.8%. The 3-year compound annual growth rate (CAGR) favors JNJ at 13.3% vs ANIK's -17.2% — a key indicator of consistent wealth creation.

MetricANIK logoANIKAnika Therapeutic…JNJ logoJNJJohnson & JohnsonSYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
YTD ReturnYear-to-date+58.0%+7.4%-17.8%-43.1%
1-Year ReturnPast 12 months+0.2%+45.5%-24.5%-47.8%
3-Year ReturnCumulative with dividends-43.1%+45.5%+2.4%+1.5%
5-Year ReturnCumulative with dividends-64.4%+43.9%+17.5%+24.7%
10-Year ReturnCumulative with dividends-66.7%+131.3%+179.2%+143.6%
CAGR (3Y)Annualised 3-year return-17.2%+13.3%+0.8%+0.5%
JNJ leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ANIK and JNJ each lead in 1 of 2 comparable metrics.

JNJ is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than ANIK's 1.10 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ANIK currently trades 90.9% from its 52-week high vs BSX's 49.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricANIK logoANIKAnika Therapeutic…JNJ logoJNJJohnson & JohnsonSYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
Beta (5Y)Sensitivity to S&P 5001.10x0.04x0.52x0.30x
52-Week HighHighest price in past year$16.24$251.71$404.87$109.50
52-Week LowLowest price in past year$7.87$146.12$284.97$53.64
% of 52W HighCurrent price vs 52-week peak+90.9%+87.9%+70.5%+49.3%
RSI (14)Momentum oscillator 0–10053.534.326.635.4
Avg Volume (50D)Average daily shares traded131K6.9M2.1M15.6M
Evenly matched — ANIK and JNJ each lead in 1 of 2 comparable metrics.

Analyst Outlook

JNJ leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ANIK as "Buy", JNJ as "Buy", SYK as "Buy", BSX as "Buy". Consensus price targets imply 69.3% upside for BSX (target: $91) vs 12.6% for JNJ (target: $249). For income investors, JNJ offers the higher dividend yield at 2.20% vs SYK's 1.18%.

MetricANIK logoANIKAnika Therapeutic…JNJ logoJNJJohnson & JohnsonSYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$249.27$389.62$91.33
# AnalystsCovering analysts6405043
Dividend YieldAnnual dividend ÷ price+2.2%+1.2%
Dividend StreakConsecutive years of raises36340
Dividend / ShareAnnual DPS$4.87$3.36
Buyback YieldShare repurchases ÷ mkt cap+4.8%+0.5%0.0%0.0%
JNJ leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

JNJ leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ANIK leads in 1 (Valuation Metrics). 1 tied.

Best OverallJohnson & Johnson (JNJ)Leads 4 of 6 categories
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ANIK vs JNJ vs SYK vs BSX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ANIK or JNJ or SYK or BSX a better buy right now?

For growth investors, Boston Scientific Corporation (BSX) is the stronger pick with 19.

9% revenue growth year-over-year, versus -5. 9% for Anika Therapeutics, Inc. (ANIK). Boston Scientific Corporation (BSX) offers the better valuation at 27. 8x trailing P/E (16. 0x forward), making it the more compelling value choice. Analysts rate Anika Therapeutics, Inc. (ANIK) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ANIK or JNJ or SYK or BSX?

On trailing P/E, Boston Scientific Corporation (BSX) is the cheapest at 27.

8x versus Johnson & Johnson at 38. 2x. On forward P/E, Boston Scientific Corporation is actually cheaper at 16. 0x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Stryker Corporation wins at 1. 28x versus Johnson & Johnson's 34. 02x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — ANIK or JNJ or SYK or BSX?

Over the past 5 years, Johnson & Johnson (JNJ) delivered a total return of +43.

9%, compared to -64. 4% for Anika Therapeutics, Inc. (ANIK). Over 10 years, the gap is even starker: SYK returned +179. 2% versus ANIK's -66. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ANIK or JNJ or SYK or BSX?

By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.

04β versus Anika Therapeutics, Inc. 's 1. 10β — meaning ANIK is approximately 2352% more volatile than JNJ relative to the S&P 500. On balance sheet safety, Anika Therapeutics, Inc. (ANIK) carries a lower debt/equity ratio of 17% versus 66% for Stryker Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — ANIK or JNJ or SYK or BSX?

By revenue growth (latest reported year), Boston Scientific Corporation (BSX) is pulling ahead at 19.

9% versus -5. 9% for Anika Therapeutics, Inc. (ANIK). On earnings-per-share growth, the picture is similar: Anika Therapeutics, Inc. grew EPS 80. 2% year-over-year, compared to -57. 8% for Johnson & Johnson. Over a 3-year CAGR, BSX leads at 16. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ANIK or JNJ or SYK or BSX?

Johnson & Johnson (JNJ) is the more profitable company, earning 15.

8% net margin versus -9. 6% for Anika Therapeutics, Inc. — meaning it keeps 15. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JNJ leads at 24. 9% versus -9. 8% for ANIK. At the gross margin level — before operating expenses — JNJ leads at 69. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ANIK or JNJ or SYK or BSX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Stryker Corporation (SYK) is the more undervalued stock at a PEG of 1. 28x versus Johnson & Johnson's 34. 02x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Boston Scientific Corporation (BSX) trades at 16. 0x forward P/E versus 19. 1x for Johnson & Johnson — 3. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for BSX: 69. 3% to $91. 33.

08

Which pays a better dividend — ANIK or JNJ or SYK or BSX?

In this comparison, JNJ (2.

2% yield), SYK (1. 2% yield) pay a dividend. ANIK, BSX do not pay a meaningful dividend and should not be held primarily for income.

09

Is ANIK or JNJ or SYK or BSX better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

04), 2. 2% yield, +131. 3% 10Y return). Both have compounded well over 10 years (JNJ: +131. 3%, ANIK: -66. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ANIK and JNJ and SYK and BSX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ANIK is a small-cap quality compounder stock; JNJ is a large-cap quality compounder stock; SYK is a mid-cap quality compounder stock; BSX is a mid-cap high-growth stock. JNJ, SYK pay a dividend while ANIK, BSX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Stocks Like

ANIK

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 35%
Run This Screen
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JNJ

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 16%
Run This Screen
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SYK

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 7%
Run This Screen
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BSX

High-Growth Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 7%
  • Net Margin > 8%
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Beat Both

Find stocks that outperform ANIK and JNJ and SYK and BSX on the metrics below

Revenue Growth>
%
(ANIK: 13.2% · JNJ: 6.8%)

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