Drug Manufacturers - General
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BIIB vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
BIIB vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Drug Manufacturers - General | Biotechnology |
| Market Cap | $27.92B | $72.97B |
| Revenue (TTM) | $9.86B | $14.92B |
| Net Income (TTM) | $1.37B | $4.42B |
| Gross Margin | 69.8% | 84.5% |
| Operating Margin | 15.6% | 24.3% |
| Forward P/E | 12.9x | 15.2x |
| Total Debt | $6.95B | $2.71B |
| Cash & Equiv. | $3.01B | $3.12B |
BIIB vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Biogen Inc. (BIIB) | 100 | 61.6 | -38.4% |
| Regeneron Pharmaceu… (REGN) | 100 | 114.6 | +14.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BIIB vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BIIB carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 0.64
- Rev growth 1.4%, EPS growth -21.1%, 3Y rev CAGR -1.2%
- Lower volatility, beta 0.64, Low D/E 38.1%, current ratio 2.68x
REGN is the clearest fit if your priority is long-term compounding.
- 87.1% 10Y total return vs BIIB's -28.5%
- 29.6% margin vs BIIB's 13.9%
- 0.5% yield; 1-year raise streak; the other pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 1.4% revenue growth vs REGN's 1.0% | |
| Value | Lower P/E (12.9x vs 15.2x) | |
| Quality / Margins | 29.6% margin vs BIIB's 13.9% | |
| Stability / Safety | Beta 0.64 vs REGN's 0.81 | |
| Dividends | 0.5% yield; 1-year raise streak; the other pay no meaningful dividend | |
| Momentum (1Y) | +55.3% vs REGN's +17.0% | |
| Efficiency (ROA) | 11.1% ROA vs BIIB's 4.7%, ROIC 8.9% vs 6.5% |
BIIB vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
BIIB vs REGN — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
REGN leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN is the larger business by revenue, generating $14.9B annually — 1.5x BIIB's $9.9B. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to BIIB's 13.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $9.9B | $14.9B |
| EBITDAEarnings before interest/tax | $2.4B | $4.2B |
| Net IncomeAfter-tax profit | $1.4B | $4.4B |
| Free Cash FlowCash after capex | $2.6B | $4.2B |
| Gross MarginGross profit ÷ Revenue | +69.8% | +84.5% |
| Operating MarginEBIT ÷ Revenue | +15.6% | +24.3% |
| Net MarginNet income ÷ Revenue | +13.9% | +29.6% |
| FCF MarginFCF ÷ Revenue | +26.6% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | +1.9% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +31.1% | -7.2% |
Valuation Metrics
BIIB leads this category, winning 5 of 6 comparable metrics.
Valuation Metrics
At 16.9x trailing earnings, REGN trades at a 21% valuation discount to BIIB's 21.4x P/E. On an enterprise value basis, BIIB's 11.3x EV/EBITDA is more attractive than REGN's 17.6x.
| Metric | ||
|---|---|---|
| Market CapShares × price | $27.9B | $73.0B |
| Enterprise ValueMkt cap + debt − cash | $31.9B | $72.6B |
| Trailing P/EPrice ÷ TTM EPS | 21.42x | 16.93x |
| Forward P/EPrice ÷ next-FY EPS est. | 12.89x | 15.20x |
| PEG RatioP/E ÷ EPS growth rate | — | 2.68x |
| EV / EBITDAEnterprise value multiple | 11.33x | 17.61x |
| Price / SalesMarket cap ÷ Revenue | 2.85x | 5.09x |
| Price / BookPrice ÷ Book value/share | 1.52x | 2.44x |
| Price / FCFMarket cap ÷ FCF | 13.62x | 17.88x |
Profitability & Efficiency
REGN leads this category, winning 8 of 8 comparable metrics.
Profitability & Efficiency
REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $8 for BIIB. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to BIIB's 0.38x.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | +7.5% | +14.3% |
| ROA (TTM)Return on assets | +4.7% | +11.1% |
| ROICReturn on invested capital | +6.5% | +8.9% |
| ROCEReturn on capital employed | +7.7% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.38x | 0.09x |
| Net DebtTotal debt minus cash | $3.9B | -$412M |
| Cash & Equiv.Liquid assets | $3.0B | $3.1B |
| Total DebtShort + long-term debt | $6.9B | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | 6.91x | 108.44x |
Total Returns (Dividends Reinvested)
REGN leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in REGN five years ago would be worth $14,651 today (with dividends reinvested), compared to $6,964 for BIIB. Over the past 12 months, BIIB leads with a +55.3% total return vs REGN's +17.0%. The 3-year compound annual growth rate (CAGR) favors REGN at -2.5% vs BIIB's -15.9% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +6.4% | -9.4% |
| 1-Year ReturnPast 12 months | +55.3% | +17.0% |
| 3-Year ReturnCumulative with dividends | -40.5% | -7.3% |
| 5-Year ReturnCumulative with dividends | -30.4% | +46.5% |
| 10-Year ReturnCumulative with dividends | -28.5% | +87.1% |
| CAGR (3Y)Annualised 3-year return | -15.9% | -2.5% |
Risk & Volatility
BIIB leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
BIIB is the less volatile stock with a 0.64 beta — it tends to amplify market swings less than REGN's 0.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIIB currently trades 93.4% from its 52-week high vs REGN's 85.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.64x | 0.81x |
| 52-Week HighHighest price in past year | $202.41 | $821.11 |
| 52-Week LowLowest price in past year | $115.25 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +93.4% | +85.5% |
| RSI (14)Momentum oscillator 0–100 | 53.2 | 39.8 |
| Avg Volume (50D)Average daily shares traded | 1.1M | 631K |
Analyst Outlook
REGN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Wall Street rates BIIB as "Buy" and REGN as "Buy". Consensus price targets imply 23.3% upside for REGN (target: $866) vs 11.8% for BIIB (target: $211). REGN is the only dividend payer here at 0.49% yield — a key consideration for income-focused portfolios.
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $211.42 | $865.68 |
| # AnalystsCovering analysts | 48 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% |
| Dividend StreakConsecutive years of raises | 0 | 1 |
| Dividend / ShareAnnual DPS | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.4% |
REGN leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BIIB leads in 2 (Valuation Metrics, Risk & Volatility).
BIIB vs REGN: Frequently Asked Questions
10 questions · data-driven answers · updated daily
01Is BIIB or REGN a better buy right now?
For growth investors, Biogen Inc.
(BIIB) is the stronger pick with 1. 4% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 16. 9x trailing P/E (15. 2x forward), making it the more compelling value choice. Analysts rate Biogen Inc. (BIIB) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — BIIB or REGN?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 16. 9x versus Biogen Inc. at 21. 4x. On forward P/E, Biogen Inc. is actually cheaper at 12. 9x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — BIIB or REGN?
Over the past 5 years, Regeneron Pharmaceuticals, Inc.
(REGN) delivered a total return of +46. 5%, compared to -30. 4% for Biogen Inc. (BIIB). Over 10 years, the gap is even starker: REGN returned +87. 1% versus BIIB's -28. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — BIIB or REGN?
By beta (market sensitivity over 5 years), Biogen Inc.
(BIIB) is the lower-risk stock at 0. 64β versus Regeneron Pharmaceuticals, Inc. 's 0. 81β — meaning REGN is approximately 26% more volatile than BIIB relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 38% for Biogen Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — BIIB or REGN?
By revenue growth (latest reported year), Biogen Inc.
(BIIB) is pulling ahead at 1. 4% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -21. 1% for Biogen Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — BIIB or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus 13. 2% for Biogen Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus 19. 1% for BIIB. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is BIIB or REGN more undervalued right now?
On forward earnings alone, Biogen Inc.
(BIIB) trades at 12. 9x forward P/E versus 15. 2x for Regeneron Pharmaceuticals, Inc. — 2. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for REGN: 23. 3% to $865. 68.
08Which pays a better dividend — BIIB or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. BIIB does not pay a meaningful dividend and should not be held primarily for income.
09Is BIIB or REGN better for a retirement portfolio?
For long-horizon retirement investors, Biogen Inc.
(BIIB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 64)). Both have compounded well over 10 years (BIIB: -28. 5%, REGN: +87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between BIIB and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: BIIB is a mid-cap quality compounder stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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