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Stock Comparison

BIO vs BRKR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.99B
5Y Perf.-47.3%
BRKR
Bruker Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$6.44B
5Y Perf.-2.3%

BIO vs BRKR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BIO logoBIO
BRKR logoBRKR
IndustryMedical - DevicesMedical - Devices
Market Cap$6.99B$6.44B
Revenue (TTM)$2.59B$3.46B
Net Income (TTM)$169M$-26M
Gross Margin51.9%45.3%
Operating Margin9.2%4.9%
Forward P/E25.2x20.0x
Total Debt$1.53B$2.04B
Cash & Equiv.$532M$299M

BIO vs BRKRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BIO
BRKR
StockMay 20May 26Return
Bio-Rad Laboratorie… (BIO)10052.7-47.3%
Bruker Corporation (BRKR)10097.7-2.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: BIO vs BRKR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BIO leads in 4 of 7 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Bruker Corporation is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
BIO
Bio-Rad Laboratories, Inc.
The Income Pick

BIO carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • beta 0.92
  • 82.9% 10Y total return vs BRKR's 59.6%
  • Lower volatility, beta 0.92, Low D/E 20.5%, current ratio 5.62x
Best for: income & stability and long-term compounding
BRKR
Bruker Corporation
The Growth Play

BRKR is the clearest fit if your priority is growth exposure.

  • Rev growth 2.1%, EPS growth -119.7%, 3Y rev CAGR 10.7%
  • 2.1% revenue growth vs BIO's 0.7%
  • Lower P/E (20.0x vs 25.2x)
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBRKR logoBRKR2.1% revenue growth vs BIO's 0.7%
ValueBRKR logoBRKRLower P/E (20.0x vs 25.2x)
Quality / MarginsBIO logoBIO6.5% margin vs BRKR's -0.8%
Stability / SafetyBIO logoBIOBeta 0.92 vs BRKR's 1.59, lower leverage
DividendsBRKR logoBRKR0.4% yield; the other pay no meaningful dividend
Momentum (1Y)BIO logoBIO+11.9% vs BRKR's +7.7%
Efficiency (ROA)BIO logoBIO2.2% ROA vs BRKR's -0.4%, ROIC 2.6% vs 4.4%

BIO vs BRKR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B
BRKRBruker Corporation
FY 2025
Product
80.5%$2.8B
Product and Service, Other
19.5%$670M

BIO vs BRKR — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBIOLAGGINGBRKR

Income & Cash Flow (Last 12 Months)

BIO leads this category, winning 4 of 6 comparable metrics.

BRKR and BIO operate at a comparable scale, with $3.5B and $2.6B in trailing revenue. BIO is the more profitable business, keeping 6.5% of every revenue dollar as net income compared to BRKR's -0.8%.

MetricBIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
RevenueTrailing 12 months$2.6B$3.5B
EBITDAEarnings before interest/tax-$315M$339M
Net IncomeAfter-tax profit$169M-$26M
Free Cash FlowCash after capex$357M$51M
Gross MarginGross profit ÷ Revenue+51.9%+45.3%
Operating MarginEBIT ÷ Revenue+9.2%+4.9%
Net MarginNet income ÷ Revenue+6.5%-0.8%
FCF MarginFCF ÷ Revenue+13.8%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year+1.1%+2.7%
EPS Growth (YoY)Latest quarter vs prior year-9.5%-81.8%
BIO leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — BIO and BRKR each lead in 3 of 6 comparable metrics.

On an enterprise value basis, BIO's 16.8x EV/EBITDA is more attractive than BRKR's 17.9x.

MetricBIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
Market CapShares × price$7.0B$6.4B
Enterprise ValueMkt cap + debt − cash$8.0B$8.2B
Trailing P/EPrice ÷ TTM EPS9.29x-282.00x
Forward P/EPrice ÷ next-FY EPS est.25.17x20.01x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple16.80x17.93x
Price / SalesMarket cap ÷ Revenue2.71x1.87x
Price / BookPrice ÷ Book value/share0.95x2.56x
Price / FCFMarket cap ÷ FCF18.67x148.71x
Evenly matched — BIO and BRKR each lead in 3 of 6 comparable metrics.

Profitability & Efficiency

BIO leads this category, winning 6 of 9 comparable metrics.

BIO delivers a 2.4% return on equity — every $100 of shareholder capital generates $2 in annual profit, vs $-1 for BRKR. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to BRKR's 0.81x. On the Piotroski fundamental quality scale (0–9), BIO scores 5/9 vs BRKR's 4/9, reflecting solid financial health.

MetricBIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
ROE (TTM)Return on equity+2.4%-1.1%
ROA (TTM)Return on assets+2.2%-0.4%
ROICReturn on invested capital+2.6%+4.4%
ROCEReturn on capital employed+2.9%+5.0%
Piotroski ScoreFundamental quality 0–954
Debt / EquityFinancial leverage0.21x0.81x
Net DebtTotal debt minus cash$999M$1.7B
Cash & Equiv.Liquid assets$532M$299M
Total DebtShort + long-term debt$1.5B$2.0B
Interest CoverageEBIT ÷ Interest expense-2.49x0.75x
BIO leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

BIO leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in BRKR five years ago would be worth $6,345 today (with dividends reinvested), compared to $4,301 for BIO. Over the past 12 months, BIO leads with a +11.9% total return vs BRKR's +7.7%. The 3-year compound annual growth rate (CAGR) favors BIO at -11.9% vs BRKR's -17.8% — a key indicator of consistent wealth creation.

MetricBIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
YTD ReturnYear-to-date-15.2%-12.0%
1-Year ReturnPast 12 months+11.9%+7.7%
3-Year ReturnCumulative with dividends-31.5%-44.4%
5-Year ReturnCumulative with dividends-57.0%-36.6%
10-Year ReturnCumulative with dividends+82.9%+59.6%
CAGR (3Y)Annualised 3-year return-11.9%-17.8%
BIO leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

BIO leads this category, winning 2 of 2 comparable metrics.

BIO is the less volatile stock with a 0.92 beta — it tends to amplify market swings less than BRKR's 1.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.

MetricBIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
Beta (5Y)Sensitivity to S&P 5000.92x1.59x
52-Week HighHighest price in past year$343.12$56.22
52-Week LowLowest price in past year$211.43$28.53
% of 52W HighCurrent price vs 52-week peak+75.5%+75.2%
RSI (14)Momentum oscillator 0–10035.352.6
Avg Volume (50D)Average daily shares traded306K1.9M
BIO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates BIO as "Buy" and BRKR as "Buy". Consensus price targets imply 23.2% upside for BRKR (target: $52) vs 20.6% for BIO (target: $313). BRKR is the only dividend payer here at 0.36% yield — a key consideration for income-focused portfolios.

MetricBIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$312.50$52.13
# AnalystsCovering analysts1432
Dividend YieldAnnual dividend ÷ price+0.4%
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS$0.15
Buyback YieldShare repurchases ÷ mkt cap+4.2%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

BIO leads in 4 of 6 categories — strongest in Income & Cash Flow and Profitability & Efficiency. 1 category is tied.

Best OverallBio-Rad Laboratories, Inc. (BIO)Leads 4 of 6 categories
Loading custom metrics...

BIO vs BRKR: Frequently Asked Questions

10 questions · data-driven answers · updated daily

01

Is BIO or BRKR a better buy right now?

For growth investors, Bruker Corporation (BRKR) is the stronger pick with 2.

1% revenue growth year-over-year, versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 3x trailing P/E (25. 2x forward), making it the more compelling value choice. Analysts rate Bio-Rad Laboratories, Inc. (BIO) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — BIO or BRKR?

On forward P/E, Bruker Corporation is actually cheaper at 20.

0x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — BIO or BRKR?

Over the past 5 years, Bruker Corporation (BRKR) delivered a total return of -36.

6%, compared to -57. 0% for Bio-Rad Laboratories, Inc. (BIO). Over 10 years, the gap is even starker: BIO returned +82. 9% versus BRKR's +59. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — BIO or BRKR?

By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.

(BIO) is the lower-risk stock at 0. 92β versus Bruker Corporation's 1. 59β — meaning BRKR is approximately 72% more volatile than BIO relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 81% for Bruker Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — BIO or BRKR?

By revenue growth (latest reported year), Bruker Corporation (BRKR) is pulling ahead at 2.

1% versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). On earnings-per-share growth, the picture is similar: Bio-Rad Laboratories, Inc. grew EPS 142. 6% year-over-year, compared to -119. 7% for Bruker Corporation. Over a 3-year CAGR, BRKR leads at 10. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — BIO or BRKR?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus -0. 3% for Bruker Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BIO leads at 10. 5% versus 6. 9% for BRKR. At the gross margin level — before operating expenses — BIO leads at 52. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is BIO or BRKR more undervalued right now?

On forward earnings alone, Bruker Corporation (BRKR) trades at 20.

0x forward P/E versus 25. 2x for Bio-Rad Laboratories, Inc. — 5. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for BRKR: 23. 2% to $52. 13.

08

Which pays a better dividend — BIO or BRKR?

In this comparison, BRKR (0.

4% yield) pays a dividend. BIO does not pay a meaningful dividend and should not be held primarily for income.

09

Is BIO or BRKR better for a retirement portfolio?

For long-horizon retirement investors, Bio-Rad Laboratories, Inc.

(BIO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 92)). Bruker Corporation (BRKR) carries a higher beta of 1. 59 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BIO: +82. 9%, BRKR: +59. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between BIO and BRKR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: BIO is a small-cap deep-value stock; BRKR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Sector: Healthcare
  • Market Cap > $100B
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Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 27%
  • Dividend Yield > 0.5%
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