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Stock Comparison

BLTE vs BEAM vs EDIT vs CRSP

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BLTE
Belite Bio, Inc

Biotechnology

HealthcareNASDAQ • US
Market Cap$4.96B
5Y Perf.+1373.1%
BEAM
Beam Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.23B
5Y Perf.-16.1%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-77.1%
CRSP
CRISPR Therapeutics AG

Biotechnology

HealthcareNASDAQ • CH
Market Cap$5.06B
5Y Perf.+5.6%

BLTE vs BEAM vs EDIT vs CRSP — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BLTE logoBLTE
BEAM logoBEAM
EDIT logoEDIT
CRSP logoCRSP
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$4.96B$3.23B$297M$5.06B
Revenue (TTM)$0.00$132M$0.00$4M
Net Income (TTM)$-49M$-65M$-160M$-569M
Gross Margin-64.2%-41.7%
Operating Margin-281.0%-134.1%
Total Debt$537K$294M$18M$395M
Cash & Equiv.$32M$295M$147M$355M

BLTE vs BEAM vs EDIT vs CRSPLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BLTE
BEAM
EDIT
CRSP
StockApr 22May 26Return
Belite Bio, Inc (BLTE)1001473.1+1373.1%
Beam Therapeutics I… (BEAM)10083.9-16.1%
Editas Medicine, In… (EDIT)10022.9-77.1%
CRISPR Therapeutics… (CRSP)100105.6+5.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: BLTE vs BEAM vs EDIT vs CRSP

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BLTE leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Beam Therapeutics Inc. is the stronger pick specifically for growth and revenue expansion and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
BLTE
Belite Bio, Inc
The Income Pick

BLTE carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • beta 0.80
  • 13.7% 10Y total return vs CRSP's 272.0%
  • Lower volatility, beta 0.80, Low D/E 0.4%, current ratio 24.31x
  • Beta 0.80, current ratio 24.31x
Best for: income & stability and long-term compounding
BEAM
Beam Therapeutics Inc.
The Growth Play

BEAM is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
  • 120.0% revenue growth vs EDIT's -100.0%
  • -4.6% ROA vs EDIT's -74.2%
Best for: growth exposure
EDIT
Editas Medicine, Inc.
The Specific-Use Pick

EDIT plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
CRSP
CRISPR Therapeutics AG
The Secondary Option

CRSP lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBEAM logoBEAM120.0% revenue growth vs EDIT's -100.0%
Quality / MarginsBLTE logoBLTE2.4% margin vs CRSP's -138.6%
Stability / SafetyBLTE logoBLTEBeta 0.80 vs EDIT's 2.52, lower leverage
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)BLTE logoBLTE+154.4% vs CRSP's +53.1%
Efficiency (ROA)BEAM logoBEAM-4.6% ROA vs EDIT's -74.2%

BLTE vs BEAM vs EDIT vs CRSP — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BLTEBelite Bio, Inc

Segment breakdown not available.

BEAMBeam Therapeutics Inc.

Segment breakdown not available.

EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M
CRSPCRISPR Therapeutics AG
FY 2025
Grant
100.0%$4M

BLTE vs BEAM vs EDIT vs CRSP — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBEAMLAGGINGCRSP

Income & Cash Flow (Last 12 Months)

BEAM leads this category, winning 4 of 6 comparable metrics.

BEAM and EDIT operate at a comparable scale, with $132M and $0 in trailing revenue. BEAM is the more profitable business, keeping -49.2% of every revenue dollar as net income compared to CRSP's -138.6%. On growth, CRSP holds the edge at +68.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBLTE logoBLTEBelite Bio, IncBEAM logoBEAMBeam Therapeutics…EDIT logoEDITEditas Medicine, …CRSP logoCRSPCRISPR Therapeuti…
RevenueTrailing 12 months$0$132M$0$4M
EBITDAEarnings before interest/tax-$50M-$355M$0-$535M
Net IncomeAfter-tax profit-$49M-$65M-$160M-$569M
Free Cash FlowCash after capex$0-$384M-$166M-$401M
Gross MarginGross profit ÷ Revenue-64.2%-41.7%
Operating MarginEBIT ÷ Revenue-2.8%-134.1%
Net MarginNet income ÷ Revenue-49.2%-138.6%
FCF MarginFCF ÷ Revenue-2.9%-97.8%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%-151.6%+68.6%
EPS Growth (YoY)Latest quarter vs prior year-61.3%+26.6%+105.5%+19.0%
BEAM leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — BLTE and BEAM and CRSP each lead in 1 of 3 comparable metrics.
MetricBLTE logoBLTEBelite Bio, IncBEAM logoBEAMBeam Therapeutics…EDIT logoEDITEditas Medicine, …CRSP logoCRSPCRISPR Therapeuti…
Market CapShares × price$5.0B$3.2B$297M$5.1B
Enterprise ValueMkt cap + debt − cash$4.9B$3.2B$168M$5.1B
Trailing P/EPrice ÷ TTM EPS-132.20x-38.85x-1.68x-8.10x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue23.14x1440.41x
Price / BookPrice ÷ Book value/share32.67x2.51x9.85x2.45x
Price / FCFMarket cap ÷ FCF
Evenly matched — BLTE and BEAM and CRSP each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

BEAM leads this category, winning 4 of 9 comparable metrics.

BEAM delivers a -5.9% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-5 for EDIT. BLTE carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), BEAM scores 4/9 vs CRSP's 1/9, reflecting mixed financial health.

MetricBLTE logoBLTEBelite Bio, IncBEAM logoBEAMBeam Therapeutics…EDIT logoEDITEditas Medicine, …CRSP logoCRSPCRISPR Therapeuti…
ROE (TTM)Return on equity-34.9%-5.9%-5.2%-30.9%
ROA (TTM)Return on assets-33.6%-4.6%-74.2%-24.5%
ROICReturn on invested capital-50.9%-31.1%-22.3%
ROCEReturn on capital employed-33.7%-33.3%-26.6%
Piotroski ScoreFundamental quality 0–93411
Debt / EquityFinancial leverage0.00x0.24x0.66x0.21x
Net DebtTotal debt minus cash-$31M-$1M-$129M$40M
Cash & Equiv.Liquid assets$32M$295M$147M$355M
Total DebtShort + long-term debt$537,000$294M$18M$395M
Interest CoverageEBIT ÷ Interest expense-1999.80x1.08x
BEAM leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

BLTE leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in BLTE five years ago would be worth $147,309 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, BLTE leads with a +154.4% total return vs CRSP's +53.1%. The 3-year compound annual growth rate (CAGR) favors BLTE at 79.9% vs EDIT's -32.0% — a key indicator of consistent wealth creation.

MetricBLTE logoBLTEBelite Bio, IncBEAM logoBEAMBeam Therapeutics…EDIT logoEDITEditas Medicine, …CRSP logoCRSPCRISPR Therapeuti…
YTD ReturnYear-to-date-2.1%+16.0%+47.8%-2.5%
1-Year ReturnPast 12 months+154.4%+93.9%+127.8%+53.1%
3-Year ReturnCumulative with dividends+482.1%-5.6%-68.5%-6.3%
5-Year ReturnCumulative with dividends+1373.1%-55.6%-91.1%-51.3%
10-Year ReturnCumulative with dividends+1373.1%+67.8%-90.0%+272.0%
CAGR (3Y)Annualised 3-year return+79.9%-1.9%-32.0%-2.2%
BLTE leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — BLTE and BEAM each lead in 1 of 2 comparable metrics.

BLTE is the less volatile stock with a 0.80 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BEAM currently trades 86.4% from its 52-week high vs EDIT's 66.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBLTE logoBLTEBelite Bio, IncBEAM logoBEAMBeam Therapeutics…EDIT logoEDITEditas Medicine, …CRSP logoCRSPCRISPR Therapeuti…
Beta (5Y)Sensitivity to S&P 5000.80x2.14x2.52x1.93x
52-Week HighHighest price in past year$200.00$36.44$4.54$78.48
52-Week LowLowest price in past year$56.10$15.35$1.29$33.50
% of 52W HighCurrent price vs 52-week peak+78.0%+86.4%+66.7%+66.8%
RSI (14)Momentum oscillator 0–10043.060.957.555.5
Avg Volume (50D)Average daily shares traded155K2.0M1.6M2.0M
Evenly matched — BLTE and BEAM each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: BLTE as "Buy", BEAM as "Buy", EDIT as "Buy", CRSP as "Buy". Consensus price targets imply 98.0% upside for EDIT (target: $6) vs 20.2% for CRSP (target: $63).

MetricBLTE logoBLTEBelite Bio, IncBEAM logoBEAMBeam Therapeutics…EDIT logoEDITEditas Medicine, …CRSP logoCRSPCRISPR Therapeuti…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$203.00$40.83$6.00$63.00
# AnalystsCovering analysts6272538
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

BEAM leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BLTE leads in 1 (Total Returns). 2 tied.

Best OverallBeam Therapeutics Inc. (BEAM)Leads 2 of 6 categories
Loading custom metrics...

BLTE vs BEAM vs EDIT vs CRSP: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is BLTE or BEAM or EDIT or CRSP a better buy right now?

For growth investors, Beam Therapeutics Inc.

(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Belite Bio, Inc (BLTE) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — BLTE or BEAM or EDIT or CRSP?

Over the past 5 years, Belite Bio, Inc (BLTE) delivered a total return of +1373%, compared to -91.

1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: BLTE returned +1373% versus EDIT's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — BLTE or BEAM or EDIT or CRSP?

By beta (market sensitivity over 5 years), Belite Bio, Inc (BLTE) is the lower-risk stock at 0.

80β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 213% more volatile than BLTE relative to the S&P 500. On balance sheet safety, Belite Bio, Inc (BLTE) carries a lower debt/equity ratio of 0% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — BLTE or BEAM or EDIT or CRSP?

By revenue growth (latest reported year), Beam Therapeutics Inc.

(BEAM) is pulling ahead at 120. 0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -49. 1% for CRISPR Therapeutics AG. Over a 3-year CAGR, CRSP leads at 100. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — BLTE or BEAM or EDIT or CRSP?

Belite Bio, Inc (BLTE) is the more profitable company, earning 0.

0% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BLTE leads at 0. 0% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — BEAM leads at 84. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — BLTE or BEAM or EDIT or CRSP?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is BLTE or BEAM or EDIT or CRSP better for a retirement portfolio?

For long-horizon retirement investors, Belite Bio, Inc (BLTE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

80), +1373% 10Y return). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BLTE: +1373%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between BLTE and BEAM and EDIT and CRSP?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: BLTE is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock; EDIT is a small-cap quality compounder stock; CRSP is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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