Biotechnology
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Side-by-side financial analysisStock Comparison
BMEA vs IMVT vs KYMR vs PRAX
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
BMEA vs IMVT vs KYMR vs PRAX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $70M | $6.90B | $7.04B | $7.70B |
| Revenue (TTM) | $0.00 | $0.00 | $51M | $0.00 |
| Net Income (TTM) | $-45M | $-506M | $-315M | $-327M |
| Gross Margin | — | — | 33.2% | — |
| Operating Margin | — | — | -7.0% | — |
| Total Debt | $2M | $72K | $82M | $110K |
| Cash & Equiv. | $56M | $902M | $357M | $357M |
BMEA vs IMVT vs KYMR vs PRAX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Apr 21 | Jun 26 | Return |
|---|---|---|---|
| Biomea Fusion, Inc. (BMEA) | 100 | 6.9 | -93.1% |
| Immunovant, Inc. (IMVT) | 100 | 214.4 | +114.4% |
| Kymera Therapeutics… (KYMR) | 100 | 189.3 | +89.3% |
| Praxis Precision Me… (PRAX) | 100 | 58.0 | -42.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BMEA vs IMVT vs KYMR vs PRAX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BMEA carries the broadest edge in this set and is the clearest fit for growth and quality.
- 65.4% revenue growth vs PRAX's -100.0%
- 3.2% margin vs KYMR's -6.1%
IMVT is the clearest fit if your priority is long-term compounding.
- 237.9% 10Y total return vs KYMR's 159.2%
KYMR is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.
- beta 0.91
- Rev growth -16.7%, EPS growth -23.8%, 3Y rev CAGR -5.8%
- Lower volatility, beta 0.91, Low D/E 5.2%, current ratio 10.47x
- Beta 0.91, current ratio 10.47x
PRAX is the clearest fit if your priority is momentum.
- +491.9% vs BMEA's -55.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 65.4% revenue growth vs PRAX's -100.0% | |
| Quality / Margins | 3.2% margin vs KYMR's -6.1% | |
| Stability / Safety | Beta 0.91 vs BMEA's 1.78, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +491.9% vs BMEA's -55.2% | |
| Efficiency (ROA) | -22.3% ROA vs BMEA's -77.1% |
BMEA vs IMVT vs KYMR vs PRAX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
BMEA vs IMVT vs KYMR vs PRAX — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BMEA leads in 1 of 6 categories
KYMR leads 1 • IMVT leads 0 • PRAX leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
BMEA leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
KYMR and PRAX operate at a comparable scale, with $51M and $0 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $51M | $0 |
| EBITDAEarnings before interest/tax | -$66M | -$532M | -$352M | -$357M |
| Net IncomeAfter-tax profit | -$45M | -$506M | -$315M | -$327M |
| Free Cash FlowCash after capex | -$56M | -$407M | -$244M | -$283M |
| Gross MarginGross profit ÷ Revenue | — | — | +33.2% | — |
| Operating MarginEBIT ÷ Revenue | — | — | -7.0% | — |
| Net MarginNet income ÷ Revenue | — | — | -6.1% | — |
| FCF MarginFCF ÷ Revenue | — | — | -4.7% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +55.5% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +78.8% | -14.1% | +13.4% | +2.7% |
Valuation Metrics
Evenly matched — BMEA and KYMR each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $70M | $6.9B | $7.0B | $7.7B |
| Enterprise ValueMkt cap + debt − cash | $15M | $6.0B | $6.8B | $7.3B |
| Trailing P/EPrice ÷ TTM EPS | -0.99x | -12.14x | -23.36x | -19.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | 179.54x | — |
| Price / BookPrice ÷ Book value/share | 2.07x | 7.19x | 4.61x | 6.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
KYMR leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-197 for BMEA. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to BMEA's 0.05x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -196.7% | -68.2% | -25.0% | -43.0% |
| ROA (TTM)Return on assets | -77.1% | -62.2% | -22.3% | -40.2% |
| ROICReturn on invested capital | — | — | -24.9% | -65.0% |
| ROCEReturn on capital employed | -153.8% | -68.3% | -27.2% | -49.3% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 | 4 | 3 |
| Debt / EquityFinancial leverage | 0.05x | 0.00x | 0.05x | 0.00x |
| Net DebtTotal debt minus cash | -$54M | -$902M | -$275M | -$357M |
| Cash & Equiv.Liquid assets | $56M | $902M | $357M | $357M |
| Total DebtShort + long-term debt | $2M | $72,000 | $82M | $110,000 |
| Interest CoverageEBIT ÷ Interest expense | — | — | -2119.53x | — |
Total Returns (Dividends Reinvested)
Evenly matched — IMVT and PRAX each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $569 for BMEA. Over the past 12 months, PRAX leads with a +491.9% total return vs BMEA's -55.2%. The 3-year compound annual growth rate (CAGR) favors PRAX at 164.8% vs BMEA's -69.2% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -12.7% | +29.8% | +18.5% | -6.9% |
| 1-Year ReturnPast 12 months | -55.2% | +110.9% | +82.3% | +491.9% |
| 3-Year ReturnCumulative with dividends | -97.1% | +55.0% | +242.9% | +1757.4% |
| 5-Year ReturnCumulative with dividends | -94.3% | +213.0% | +70.4% | -14.2% |
| 10-Year ReturnCumulative with dividends | -93.1% | +237.9% | +159.2% | -36.1% |
| CAGR (3Y)Annualised 3-year return | -69.2% | +15.7% | +50.8% | +164.8% |
Risk & Volatility
Evenly matched — IMVT and KYMR each lead in 1 of 2 comparable metrics.
Risk & Volatility
KYMR is the less volatile stock with a 0.91 beta — it tends to amplify market swings less than BMEA's 1.78 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 92.7% from its 52-week high vs BMEA's 38.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.78x | 1.66x | 0.91x | 1.55x |
| 52-Week HighHighest price in past year | $3.08 | $36.27 | $103.00 | $366.52 |
| 52-Week LowLowest price in past year | $0.87 | $14.32 | $36.65 | $37.19 |
| % of 52W HighCurrent price vs 52-week peak | +38.0% | +92.7% | +83.7% | +72.7% |
| RSI (14)Momentum oscillator 0–100 | 38.2 | 57.9 | 56.8 | 31.9 |
| Avg Volume (50D)Average daily shares traded | 1.5M | 1.9M | 492K | 396K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: BMEA as "Buy", IMVT as "Buy", KYMR as "Buy", PRAX as "Buy". Consensus price targets imply 1626.5% upside for BMEA (target: $20) vs 29.9% for IMVT (target: $44).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $20.20 | $43.67 | $112.60 | $607.15 |
| # AnalystsCovering analysts | 13 | 23 | 26 | 16 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
BMEA leads in 1 of 6 categories (Income & Cash Flow). KYMR leads in 1 (Profitability & Efficiency). 3 tied.
BMEA vs IMVT vs KYMR vs PRAX: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is BMEA or IMVT or KYMR or PRAX a better buy right now?
For growth investors, Kymera Therapeutics, Inc.
(KYMR) is the stronger pick with -16. 7% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). Analysts rate Biomea Fusion, Inc. (BMEA) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — BMEA or IMVT or KYMR or PRAX?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +213. 0%, compared to -94. 3% for Biomea Fusion, Inc. (BMEA). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus BMEA's -93. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — BMEA or IMVT or KYMR or PRAX?
By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.
(KYMR) is the lower-risk stock at 0. 91β versus Biomea Fusion, Inc. 's 1. 78β — meaning BMEA is approximately 94% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 5% for Biomea Fusion, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — BMEA or IMVT or KYMR or PRAX?
By revenue growth (latest reported year), Kymera Therapeutics, Inc.
(KYMR) is pulling ahead at -16. 7% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Biomea Fusion, Inc. grew EPS 69. 2% year-over-year, compared to -32. 0% for Praxis Precision Medicines, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — BMEA or IMVT or KYMR or PRAX?
Biomea Fusion, Inc.
(BMEA) is the more profitable company, earning 0. 0% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BMEA leads at 0. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — BMEA or IMVT or KYMR or PRAX?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is BMEA or IMVT or KYMR or PRAX better for a retirement portfolio?
For long-horizon retirement investors, Kymera Therapeutics, Inc.
(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 91), +159. 2% 10Y return). Biomea Fusion, Inc. (BMEA) carries a higher beta of 1. 78 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +159. 2%, BMEA: -93. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between BMEA and IMVT and KYMR and PRAX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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