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CELC vs KYMR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
CELC vs KYMR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $5.66B | $6.91B |
| Revenue (TTM) | $0.00 | $51M |
| Net Income (TTM) | $-163M | $-315M |
| Gross Margin | — | 33.2% |
| Operating Margin | — | -7.0% |
| Total Debt | $98M | $82M |
| Cash & Equiv. | $23M | $357M |
CELC vs KYMR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Aug 20 | May 26 | Return |
|---|---|---|---|
| Celcuity Inc. (CELC) | 100 | 2355.1 | +2255.1% |
| Kymera Therapeutics… (KYMR) | 100 | 265.3 | +165.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CELC vs KYMR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CELC is the clearest fit if your priority is growth exposure and long-term compounding.
- EPS growth -5.2%
- 8.1% 10Y total return vs KYMR's 154.4%
- 0.6% margin vs KYMR's -6.1%
KYMR carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 1.15
- Lower volatility, beta 1.15, Low D/E 5.2%, current ratio 10.47x
- Beta 1.15, current ratio 10.47x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -16.7% revenue growth vs CELC's -73.2% | |
| Quality / Margins | 0.6% margin vs KYMR's -6.1% | |
| Stability / Safety | Beta 1.15 vs CELC's 1.71, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +11.8% vs KYMR's +190.7% | |
| Efficiency (ROA) | -22.3% ROA vs CELC's -58.0%, ROIC -24.9% vs -50.3% |
CELC vs KYMR — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
KYMR leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
KYMR and CELC operate at a comparable scale, with $51M and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $51M |
| EBITDAEarnings before interest/tax | -$159M | -$352M |
| Net IncomeAfter-tax profit | -$163M | -$315M |
| Free Cash FlowCash after capex | -$145M | -$244M |
| Gross MarginGross profit ÷ Revenue | — | +33.2% |
| Operating MarginEBIT ÷ Revenue | — | -7.0% |
| Net MarginNet income ÷ Revenue | — | -6.1% |
| FCF MarginFCF ÷ Revenue | — | -4.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +55.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -31.4% | +13.4% |
Valuation Metrics
Evenly matched — CELC and KYMR each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $5.7B | $6.9B |
| Enterprise ValueMkt cap + debt − cash | $5.7B | $6.6B |
| Trailing P/EPrice ÷ TTM EPS | -46.19x | -22.93x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 176.26x |
| Price / BookPrice ÷ Book value/share | 44.60x | 4.52x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
KYMR leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-179 for CELC. KYMR carries lower financial leverage with a 0.05x debt-to-equity ratio, signaling a more conservative balance sheet compared to CELC's 0.85x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs CELC's 1/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -179.0% | -25.0% |
| ROA (TTM)Return on assets | -58.0% | -22.3% |
| ROICReturn on invested capital | -50.3% | -24.9% |
| ROCEReturn on capital employed | -58.0% | -27.2% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 |
| Debt / EquityFinancial leverage | 0.85x | 0.05x |
| Net DebtTotal debt minus cash | $75M | -$275M |
| Cash & Equiv.Liquid assets | $23M | $357M |
| Total DebtShort + long-term debt | $98M | $82M |
| Interest CoverageEBIT ÷ Interest expense | -5.02x | -2119.53x |
Total Returns (Dividends Reinvested)
CELC leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CELC five years ago would be worth $48,161 today (with dividends reinvested), compared to $19,212 for KYMR. Over the past 12 months, CELC leads with a +1184.0% total return vs KYMR's +190.7%. The 3-year compound annual growth rate (CAGR) favors CELC at 140.6% vs KYMR's 45.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +30.0% | +16.3% |
| 1-Year ReturnPast 12 months | +1184.0% | +190.7% |
| 3-Year ReturnCumulative with dividends | +1292.0% | +205.1% |
| 5-Year ReturnCumulative with dividends | +381.6% | +92.1% |
| 10-Year ReturnCumulative with dividends | +814.7% | +154.4% |
| CAGR (3Y)Annualised 3-year return | +140.6% | +45.0% |
Risk & Volatility
Evenly matched — CELC and KYMR each lead in 1 of 2 comparable metrics.
Risk & Volatility
KYMR is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than CELC's 1.71 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CELC currently trades 86.6% from its 52-week high vs KYMR's 82.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.71x | 1.15x |
| 52-Week HighHighest price in past year | $151.02 | $103.00 |
| 52-Week LowLowest price in past year | $9.51 | $28.06 |
| % of 52W HighCurrent price vs 52-week peak | +86.6% | +82.2% |
| RSI (14)Momentum oscillator 0–100 | 63.4 | 54.1 |
| Avg Volume (50D)Average daily shares traded | 800K | 602K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates CELC as "Buy" and KYMR as "Buy". Consensus price targets imply 38.3% upside for KYMR (target: $117) vs -4.6% for CELC (target: $125).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $124.75 | $117.06 |
| # AnalystsCovering analysts | 9 | 26 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
KYMR leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CELC leads in 1 (Total Returns). 2 tied.
CELC vs KYMR: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is CELC or KYMR a better buy right now?
Analysts rate Celcuity Inc.
(CELC) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CELC or KYMR?
Over the past 5 years, Celcuity Inc.
(CELC) delivered a total return of +381. 6%, compared to +92. 1% for Kymera Therapeutics, Inc. (KYMR). Over 10 years, the gap is even starker: CELC returned +814. 7% versus KYMR's +154. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CELC or KYMR?
By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.
(KYMR) is the lower-risk stock at 1. 15β versus Celcuity Inc. 's 1. 71β — meaning CELC is approximately 49% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Kymera Therapeutics, Inc. (KYMR) carries a lower debt/equity ratio of 5% versus 85% for Celcuity Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CELC or KYMR?
On earnings-per-share growth, the picture is similar: Celcuity Inc.
grew EPS -5. 2% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CELC or KYMR?
Celcuity Inc.
(CELC) is the more profitable company, earning 0. 0% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CELC leads at 0. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CELC or KYMR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CELC or KYMR better for a retirement portfolio?
For long-horizon retirement investors, Kymera Therapeutics, Inc.
(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), +154. 4% 10Y return). Celcuity Inc. (CELC) carries a higher beta of 1. 71 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +154. 4%, CELC: +814. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CELC and KYMR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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