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CELU vs FATE vs CRSP vs NTLA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
CELU vs FATE vs CRSP vs NTLA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $21M | $276M | $5.29B | $1.66B |
| Revenue (TTM) | $27M | $7M | $4M | $68M |
| Net Income (TTM) | $-92M | $-136M | $-569M | $-413M |
| Gross Margin | 76.0% | — | -41.7% | -25.6% |
| Operating Margin | -230.9% | -22.2% | -134.1% | -6.5% |
| Total Debt | $41M | $78M | $395M | $93M |
| Cash & Equiv. | $6M | $47M | $355M | $155M |
CELU vs FATE vs CRSP vs NTLA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Celularity Inc. (CELU) | 100 | 0.9 | -99.1% |
| Fate Therapeutics, … (FATE) | 100 | 7.4 | -92.6% |
| CRISPR Therapeutics… (CRSP) | 100 | 84.9 | -15.1% |
| Intellia Therapeuti… (NTLA) | 100 | 80.5 | -19.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CELU vs FATE vs CRSP vs NTLA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CELU carries the broadest edge in this set and is the clearest fit for income & stability.
- Dividend streak 1 yrs, beta 1.40, yield 26.2%
- -345.4% margin vs CRSP's -138.6%
- Beta 1.40 vs NTLA's 2.21
- 26.2% yield; 1-year raise streak; the other 3 pay no meaningful dividend
FATE is the #2 pick in this set and the best alternative if momentum is your priority.
- +132.0% vs CELU's -47.0%
CRSP is the clearest fit if your priority is long-term compounding and sleep-well-at-night.
- 289.1% 10Y total return vs FATE's 38.2%
- Lower volatility, beta 1.87, Low D/E 20.5%, current ratio 13.32x
- Beta 1.87, current ratio 13.32x
- -24.5% ROA vs CELU's -77.9%, ROIC -22.3% vs -125.0%
NTLA is the clearest fit if your priority is growth exposure.
- Rev growth 16.9%, EPS growth 27.4%, 3Y rev CAGR 9.1%
- 16.9% revenue growth vs CRSP's -90.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 16.9% revenue growth vs CRSP's -90.0% | |
| Quality / Margins | -345.4% margin vs CRSP's -138.6% | |
| Stability / Safety | Beta 1.40 vs NTLA's 2.21 | |
| Dividends | 26.2% yield; 1-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +132.0% vs CELU's -47.0% | |
| Efficiency (ROA) | -24.5% ROA vs CELU's -77.9%, ROIC -22.3% vs -125.0% |
CELU vs FATE vs CRSP vs NTLA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
CELU vs FATE vs CRSP vs NTLA — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
CRSP leads in 2 of 6 categories
CELU leads 1 • FATE leads 0 • NTLA leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
CELU leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NTLA is the larger business by revenue, generating $68M annually — 16.5x CRSP's $4M. CELU is the more profitable business, keeping -3.5% of every revenue dollar as net income compared to CRSP's -138.6%. On growth, NTLA holds the edge at +78.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $27M | $7M | $4M | $68M |
| EBITDAEarnings before interest/tax | -$54M | -$148M | -$535M | -$431M |
| Net IncomeAfter-tax profit | -$92M | -$136M | -$569M | -$413M |
| Free Cash FlowCash after capex | -$13M | -$88M | -$401M | -$396M |
| Gross MarginGross profit ÷ Revenue | +76.0% | — | -41.7% | -25.6% |
| Operating MarginEBIT ÷ Revenue | -2.3% | -22.2% | -134.1% | -6.5% |
| Net MarginNet income ÷ Revenue | -3.5% | -20.5% | -138.6% | -6.1% |
| FCF MarginFCF ÷ Revenue | -49.9% | -13.2% | -97.8% | -5.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -77.4% | -26.4% | +68.6% | +78.8% |
| EPS Growth (YoY)Latest quarter vs prior year | -59.7% | +38.6% | +19.0% | +34.6% |
Valuation Metrics
Evenly matched — CELU and FATE and CRSP each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $21M | $276M | $5.3B | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $56M | $307M | $5.3B | $1.6B |
| Trailing P/EPrice ÷ TTM EPS | -0.25x | -2.08x | -8.47x | -3.70x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 0.80x | 41.49x | 1506.63x | 24.60x |
| Price / BookPrice ÷ Book value/share | — | 1.37x | 2.57x | 2.27x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
CRSP leads this category, winning 4 of 8 comparable metrics.
Profitability & Efficiency
CRSP delivers a -30.9% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-66 for FATE. NTLA carries lower financial leverage with a 0.14x debt-to-equity ratio, signaling a more conservative balance sheet compared to FATE's 0.38x. On the Piotroski fundamental quality scale (0–9), NTLA scores 4/9 vs CRSP's 1/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -65.8% | -30.9% | -56.6% |
| ROA (TTM)Return on assets | -77.9% | -42.7% | -24.5% | -45.2% |
| ROICReturn on invested capital | -125.0% | -36.5% | -22.3% | -44.0% |
| ROCEReturn on capital employed | -116.1% | -43.1% | -26.6% | -48.5% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 | 1 | 4 |
| Debt / EquityFinancial leverage | — | 0.38x | 0.21x | 0.14x |
| Net DebtTotal debt minus cash | $35M | $31M | $40M | -$62M |
| Cash & Equiv.Liquid assets | $6M | $47M | $355M | $155M |
| Total DebtShort + long-term debt | $41M | $78M | $395M | $93M |
| Interest CoverageEBIT ÷ Interest expense | -12.58x | — | — | — |
Total Returns (Dividends Reinvested)
CRSP leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CRSP five years ago would be worth $5,404 today (with dividends reinvested), compared to $87 for CELU. Over the past 12 months, FATE leads with a +132.0% total return vs CELU's -47.0%. The 3-year compound annual growth rate (CAGR) favors CRSP at -0.7% vs CELU's -42.3% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -27.3% | +141.4% | +2.0% | +53.0% |
| 1-Year ReturnPast 12 months | -47.0% | +132.0% | +51.7% | +70.2% |
| 3-Year ReturnCumulative with dividends | -80.8% | -56.1% | -2.0% | -67.4% |
| 5-Year ReturnCumulative with dividends | -99.1% | -96.8% | -46.0% | -76.9% |
| 10-Year ReturnCumulative with dividends | -99.1% | +38.2% | +289.1% | -41.3% |
| CAGR (3Y)Annualised 3-year return | -42.3% | -24.0% | -0.7% | -31.2% |
Risk & Volatility
Evenly matched — CELU and FATE each lead in 1 of 2 comparable metrics.
Risk & Volatility
CELU is the less volatile stock with a 1.40 beta — it tends to amplify market swings less than NTLA's 2.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FATE currently trades 97.0% from its 52-week high vs CELU's 20.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.40x | 1.99x | 1.87x | 2.21x |
| 52-Week HighHighest price in past year | $4.35 | $2.46 | $78.48 | $28.25 |
| 52-Week LowLowest price in past year | $0.87 | $0.91 | $34.12 | $6.83 |
| % of 52W HighCurrent price vs 52-week peak | +20.2% | +97.0% | +69.9% | +49.9% |
| RSI (14)Momentum oscillator 0–100 | 28.9 | 82.9 | 49.4 | 49.5 |
| Avg Volume (50D)Average daily shares traded | 191K | 1.9M | 1.9M | 5.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: FATE as "Buy", CRSP as "Buy", NTLA as "Buy". Consensus price targets imply 1552.7% upside for FATE (target: $40) vs 14.9% for CRSP (target: $63). CELU is the only dividend payer here at 26.19% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $39.50 | $63.00 | $20.00 |
| # AnalystsCovering analysts | — | 31 | 38 | 39 |
| Dividend YieldAnnual dividend ÷ price | +26.2% | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | — | — | — |
| Dividend / ShareAnnual DPS | $0.23 | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
CRSP leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). CELU leads in 1 (Income & Cash Flow). 2 tied.
CELU vs FATE vs CRSP vs NTLA: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is CELU or FATE or CRSP or NTLA a better buy right now?
For growth investors, Intellia Therapeutics, Inc.
(NTLA) is the stronger pick with 16. 9% revenue growth year-over-year, versus -90. 0% for CRISPR Therapeutics AG (CRSP). Analysts rate Fate Therapeutics, Inc. (FATE) a "Buy" — based on 31 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CELU or FATE or CRSP or NTLA?
Over the past 5 years, CRISPR Therapeutics AG (CRSP) delivered a total return of -46.
0%, compared to -99. 1% for Celularity Inc. (CELU). Over 10 years, the gap is even starker: CRSP returned +289. 1% versus CELU's -99. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CELU or FATE or CRSP or NTLA?
By beta (market sensitivity over 5 years), Celularity Inc.
(CELU) is the lower-risk stock at 1. 40β versus Intellia Therapeutics, Inc. 's 2. 21β — meaning NTLA is approximately 58% more volatile than CELU relative to the S&P 500. On balance sheet safety, Intellia Therapeutics, Inc. (NTLA) carries a lower debt/equity ratio of 14% versus 38% for Fate Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CELU or FATE or CRSP or NTLA?
By revenue growth (latest reported year), Intellia Therapeutics, Inc.
(NTLA) is pulling ahead at 16. 9% versus -90. 0% for CRISPR Therapeutics AG (CRSP). On earnings-per-share growth, the picture is similar: Fate Therapeutics, Inc. grew EPS 29. 9% year-over-year, compared to -49. 1% for CRISPR Therapeutics AG. Over a 3-year CAGR, CRSP leads at 100. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CELU or FATE or CRSP or NTLA?
Celularity Inc.
(CELU) is the more profitable company, earning -345. 8% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps -345. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CELU leads at -230. 9% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — NTLA leads at 76. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CELU or FATE or CRSP or NTLA?
In this comparison, CELU (26.
2% yield) pays a dividend. FATE, CRSP, NTLA do not pay a meaningful dividend and should not be held primarily for income.
07Is CELU or FATE or CRSP or NTLA better for a retirement portfolio?
For long-horizon retirement investors, Celularity Inc.
(CELU) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (26. 2% yield). Intellia Therapeutics, Inc. (NTLA) carries a higher beta of 2. 21 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CELU: -99. 1%, NTLA: -41. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CELU and FATE and CRSP and NTLA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CELU is a small-cap income-oriented stock; FATE is a small-cap quality compounder stock; CRSP is a small-cap quality compounder stock; NTLA is a small-cap high-growth stock. CELU pays a dividend while FATE, CRSP, NTLA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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