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CLDX vs DBVT vs ALKS vs IMVT vs ABBV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CLDX
Celldex Therapeutics, Inc.

Biotechnology

NASDAQ • US
Market Cap$2.22B
5Y Perf.+1147.9%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-58.8%
ALKS
Alkermes plc

Biotechnology

HealthcareNASDAQ • IE
Market Cap$5.90B
5Y Perf.+116.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+6.1%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+118.7%

CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CLDX logoCLDX
DBVT logoDBVT
ALKS logoALKS
IMVT logoIMVT
ABBV logoABBV
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - General
Market Cap$2.22B$1712.35T$5.90B$5.53B$358.42B
Revenue (TTM)$2M$0.00$1.56B$0.00$61.16B
Net Income (TTM)$-259M$-168M$153M$-464M$4.23B
Gross Margin100.0%65.4%70.2%
Operating Margin-191.6%12.3%26.7%
Forward P/E24.8x14.3x
Total Debt$2M$22M$70M$98K$69.07B
Cash & Equiv.$29M$194M$1.12B$714M$5.23B

CLDX vs DBVT vs ALKS vs IMVT vs ABBVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CLDX
DBVT
ALKS
IMVT
ABBV
StockMay 20May 26Return
Celldex Therapeutic… (CLDX)1001247.9+1147.9%
DBV Technologies S.… (DBVT)10041.2-58.8%
Alkermes plc (ALKS)100216.4+116.4%
Immunovant, Inc. (IMVT)100106.1+6.1%
AbbVie Inc. (ABBV)100218.7+118.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: CLDX vs DBVT vs ALKS vs IMVT vs ABBV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV leads in 4 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Alkermes plc is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. DBVT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
CLDX
Celldex Therapeutics, Inc.
The Secondary Option

CLDX lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: portfolio exposure
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT ranks third and is worth considering specifically for momentum.

  • +110.4% vs ABBV's +11.3%
Best for: momentum
ALKS
Alkermes plc
The Quality Compounder

ALKS is the #2 pick in this set and the best alternative if quality and efficiency is your priority.

  • 9.8% margin vs CLDX's -172.5%
  • 5.4% ROA vs DBVT's -89.0%
Best for: quality and efficiency
IMVT
Immunovant, Inc.
The Defensive Pick

IMVT is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
Best for: sleep-well-at-night and defensive
ABBV
AbbVie Inc.
The Income Pick

ABBV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 13 yrs, beta 0.34, yield 3.2%
  • Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
  • 295.5% 10Y total return vs IMVT's 173.6%
  • 8.6% revenue growth vs DBVT's -100.0%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthABBV logoABBV8.6% revenue growth vs DBVT's -100.0%
ValueABBV logoABBVBetter valuation composite
Quality / MarginsALKS logoALKS9.8% margin vs CLDX's -172.5%
Stability / SafetyABBV logoABBVBeta 0.34 vs CLDX's 1.73
DividendsABBV logoABBV3.2% yield; 13-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)DBVT logoDBVT+110.4% vs ABBV's +11.3%
Efficiency (ROA)ALKS logoALKS5.4% ROA vs DBVT's -89.0%

CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CLDXCelldex Therapeutics, Inc.
FY 2025
Grant
93.7%$1M
Service
6.3%$97,000
DBVTDBV Technologies S.A.

Segment breakdown not available.

ALKSAlkermes plc
FY 2025
Vivitrol
39.8%$468M
Aristada And Aristada Initio
31.5%$370M
Manufactured Product And Royalty
24.8%$291M
Manufacturing Revenue
3.9%$46M
IMVTImmunovant, Inc.

Segment breakdown not available.

ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B

CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABBVLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

ABBV leads this category, winning 3 of 6 comparable metrics.

ABBV and IMVT operate at a comparable scale, with $61.2B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to CLDX's -172.5%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCLDX logoCLDXCelldex Therapeut…DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcIMVT logoIMVTImmunovant, Inc.ABBV logoABBVAbbVie Inc.
RevenueTrailing 12 months$2M$0$1.6B$0$61.2B
EBITDAEarnings before interest/tax-$284M-$112M$212M-$487M$24.5B
Net IncomeAfter-tax profit-$259M-$168M$153M-$464M$4.2B
Free Cash FlowCash after capex-$213M-$151M$392M-$423M$18.7B
Gross MarginGross profit ÷ Revenue+100.0%+65.4%+70.2%
Operating MarginEBIT ÷ Revenue-191.6%+12.3%+26.7%
Net MarginNet income ÷ Revenue-172.5%+9.8%+6.9%
FCF MarginFCF ÷ Revenue-142.2%+25.1%+30.6%
Rev. Growth (YoY)Latest quarter vs prior year-93.6%+28.2%+10.0%
EPS Growth (YoY)Latest quarter vs prior year-73.2%+91.5%-4.1%+19.7%+57.4%
ABBV leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

ALKS leads this category, winning 2 of 5 comparable metrics.

At 24.8x trailing earnings, ALKS trades at a 71% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, ABBV's 15.0x EV/EBITDA is more attractive than ALKS's 17.3x.

MetricCLDX logoCLDXCelldex Therapeut…DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcIMVT logoIMVTImmunovant, Inc.ABBV logoABBVAbbVie Inc.
Market CapShares × price$2.2B$1712.35T$5.9B$5.5B$358.4B
Enterprise ValueMkt cap + debt − cash$2.2B$1712.35T$4.9B$4.8B$422.3B
Trailing P/EPrice ÷ TTM EPS-8.54x-0.76x24.76x-9.97x85.50x
Forward P/EPrice ÷ next-FY EPS est.14.28x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple17.25x14.96x
Price / SalesMarket cap ÷ Revenue1477.19x4.00x5.86x
Price / BookPrice ÷ Book value/share4.20x0.66x3.28x5.83x
Price / FCFMarket cap ÷ FCF12.28x20.12x
ALKS leads this category, winning 2 of 5 comparable metrics.

Profitability & Efficiency

ALKS leads this category, winning 4 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DBVT's 0.13x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs IMVT's 2/9, reflecting strong financial health.

MetricCLDX logoCLDXCelldex Therapeut…DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcIMVT logoIMVTImmunovant, Inc.ABBV logoABBVAbbVie Inc.
ROE (TTM)Return on equity-41.7%-130.2%+8.8%-47.1%+62.1%
ROA (TTM)Return on assets-38.9%-89.0%+5.4%-44.1%+3.1%
ROICReturn on invested capital-35.2%+18.9%+23.9%
ROCEReturn on capital employed-44.7%-145.7%+14.2%-66.1%+21.5%
Piotroski ScoreFundamental quality 0–934726
Debt / EquityFinancial leverage0.00x0.13x0.04x0.00x
Net DebtTotal debt minus cash-$27M-$172M-$1.0B-$714M$63.8B
Cash & Equiv.Liquid assets$29M$194M$1.1B$714M$5.2B
Total DebtShort + long-term debt$2M$22M$70M$98,000$69.1B
Interest CoverageEBIT ÷ Interest expense-189.82x32.30x3.28x
ALKS leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ABBV leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs CLDX's -0.0% — a key indicator of consistent wealth creation.

MetricCLDX logoCLDXCelldex Therapeut…DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcIMVT logoIMVTImmunovant, Inc.ABBV logoABBVAbbVie Inc.
YTD ReturnYear-to-date+23.4%+4.9%+25.3%+5.1%-10.1%
1-Year ReturnPast 12 months+76.2%+110.4%+16.5%+96.1%+11.3%
3-Year ReturnCumulative with dividends-0.1%+19.7%+14.5%+40.9%+50.4%
5-Year ReturnCumulative with dividends+22.0%-69.1%+60.9%+62.4%+101.3%
10-Year ReturnCumulative with dividends-43.3%-87.0%-11.0%+173.6%+295.5%
CAGR (3Y)Annualised 3-year return-0.0%+6.2%+4.6%+12.1%+14.6%
ABBV leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ALKS and ABBV each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than CLDX's 1.73 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs DBVT's 76.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCLDX logoCLDXCelldex Therapeut…DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcIMVT logoIMVTImmunovant, Inc.ABBV logoABBVAbbVie Inc.
Beta (5Y)Sensitivity to S&P 5001.73x1.26x1.06x1.37x0.34x
52-Week HighHighest price in past year$35.79$26.18$36.60$30.09$244.81
52-Week LowLowest price in past year$17.85$7.53$25.17$13.36$176.57
% of 52W HighCurrent price vs 52-week peak+93.1%+76.3%+96.7%+90.5%+82.8%
RSI (14)Momentum oscillator 0–10060.748.160.260.246.8
Avg Volume (50D)Average daily shares traded985K252K2.3M1.4M5.8M
Evenly matched — ALKS and ABBV each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: CLDX as "Buy", DBVT as "Buy", ALKS as "Buy", IMVT as "Buy", ABBV as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 24.3% for ALKS (target: $44). ABBV is the only dividend payer here at 3.24% yield — a key consideration for income-focused portfolios.

MetricCLDX logoCLDXCelldex Therapeut…DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcIMVT logoIMVTImmunovant, Inc.ABBV logoABBVAbbVie Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$45.00$46.33$44.00$45.50$256.64
# AnalystsCovering analysts1915282341
Dividend YieldAnnual dividend ÷ price+3.2%
Dividend StreakConsecutive years of raises0013
Dividend / ShareAnnual DPS$6.57
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.5%0.0%+0.3%
ABBV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

ABBV leads in 3 of 6 categories (Income & Cash Flow, Total Returns). ALKS leads in 2 (Valuation Metrics, Profitability & Efficiency). 1 tied.

Best OverallAbbVie Inc. (ABBV)Leads 3 of 6 categories
Loading custom metrics...

CLDX vs DBVT vs ALKS vs IMVT vs ABBV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is CLDX or DBVT or ALKS or IMVT or ABBV a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -78. 6% for Celldex Therapeutics, Inc. (CLDX). Alkermes plc (ALKS) offers the better valuation at 24. 8x trailing P/E, making it the more compelling value choice. Analysts rate Celldex Therapeutics, Inc. (CLDX) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — CLDX or DBVT or ALKS or IMVT or ABBV?

On trailing P/E, Alkermes plc (ALKS) is the cheapest at 24.

8x versus AbbVie Inc. at 85. 5x.

03

Which is the better long-term investment — CLDX or DBVT or ALKS or IMVT or ABBV?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +101. 3%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — CLDX or DBVT or ALKS or IMVT or ABBV?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus Celldex Therapeutics, Inc. 's 1. 73β — meaning CLDX is approximately 410% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 13% for DBV Technologies S. A. — giving it more financial flexibility in a downturn.

05

Which is growing faster — CLDX or DBVT or ALKS or IMVT or ABBV?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus -78. 6% for Celldex Therapeutics, Inc. (CLDX). On earnings-per-share growth, the picture is similar: AbbVie Inc. grew EPS -0. 8% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ALKS leads at 9. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — CLDX or DBVT or ALKS or IMVT or ABBV?

Alkermes plc (ALKS) is the more profitable company, earning 16.

4% net margin versus -172. 5% for Celldex Therapeutics, Inc. — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -191. 6% for CLDX. At the gross margin level — before operating expenses — CLDX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is CLDX or DBVT or ALKS or IMVT or ABBV more undervalued right now?

Analyst consensus price targets imply the most upside for DBVT: 131.

8% to $46. 33.

08

Which pays a better dividend — CLDX or DBVT or ALKS or IMVT or ABBV?

In this comparison, ABBV (3.

2% yield) pays a dividend. CLDX, DBVT, ALKS, IMVT do not pay a meaningful dividend and should not be held primarily for income.

09

Is CLDX or DBVT or ALKS or IMVT or ABBV better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Celldex Therapeutics, Inc. (CLDX) carries a higher beta of 1. 73 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABBV: +295. 5%, CLDX: -43. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between CLDX and DBVT and ALKS and IMVT and ABBV?

Both stocks operate in the null sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CLDX is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; ALKS is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock. ABBV pays a dividend while CLDX, DBVT, ALKS, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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