Biotechnology
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CLDX vs DBVT vs ALKS vs IMVT vs ABBV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Drug Manufacturers - General
CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General |
| Market Cap | $2.22B | $1712.35T | $5.90B | $5.53B | $358.42B |
| Revenue (TTM) | $2M | $0.00 | $1.56B | $0.00 | $61.16B |
| Net Income (TTM) | $-259M | $-168M | $153M | $-464M | $4.23B |
| Gross Margin | 100.0% | — | 65.4% | — | 70.2% |
| Operating Margin | -191.6% | — | 12.3% | — | 26.7% |
| Forward P/E | — | — | 24.8x | — | 14.3x |
| Total Debt | $2M | $22M | $70M | $98K | $69.07B |
| Cash & Equiv. | $29M | $194M | $1.12B | $714M | $5.23B |
CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Celldex Therapeutic… (CLDX) | 100 | 1247.9 | +1147.9% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Alkermes plc (ALKS) | 100 | 216.4 | +116.4% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| AbbVie Inc. (ABBV) | 100 | 218.7 | +118.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CLDX vs DBVT vs ALKS vs IMVT vs ABBV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CLDX lags the leaders in this set but could rank higher in a more targeted comparison.
DBVT ranks third and is worth considering specifically for momentum.
- +110.4% vs ABBV's +11.3%
ALKS is the #2 pick in this set and the best alternative if quality and efficiency is your priority.
- 9.8% margin vs CLDX's -172.5%
- 5.4% ROA vs DBVT's -89.0%
IMVT is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
ABBV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
- 295.5% 10Y total return vs IMVT's 173.6%
- 8.6% revenue growth vs DBVT's -100.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs DBVT's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 9.8% margin vs CLDX's -172.5% | |
| Stability / Safety | Beta 0.34 vs CLDX's 1.73 | |
| Dividends | 3.2% yield; 13-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +110.4% vs ABBV's +11.3% | |
| Efficiency (ROA) | 5.4% ROA vs DBVT's -89.0% |
CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
CLDX vs DBVT vs ALKS vs IMVT vs ABBV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ABBV leads in 3 of 6 categories
ALKS leads 2 • CLDX leads 0 • DBVT leads 0 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ABBV leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV and IMVT operate at a comparable scale, with $61.2B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to CLDX's -172.5%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $2M | $0 | $1.6B | $0 | $61.2B |
| EBITDAEarnings before interest/tax | -$284M | -$112M | $212M | -$487M | $24.5B |
| Net IncomeAfter-tax profit | -$259M | -$168M | $153M | -$464M | $4.2B |
| Free Cash FlowCash after capex | -$213M | -$151M | $392M | -$423M | $18.7B |
| Gross MarginGross profit ÷ Revenue | +100.0% | — | +65.4% | — | +70.2% |
| Operating MarginEBIT ÷ Revenue | -191.6% | — | +12.3% | — | +26.7% |
| Net MarginNet income ÷ Revenue | -172.5% | — | +9.8% | — | +6.9% |
| FCF MarginFCF ÷ Revenue | -142.2% | — | +25.1% | — | +30.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | -93.6% | — | +28.2% | — | +10.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -73.2% | +91.5% | -4.1% | +19.7% | +57.4% |
Valuation Metrics
ALKS leads this category, winning 2 of 5 comparable metrics.
Valuation Metrics
At 24.8x trailing earnings, ALKS trades at a 71% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, ABBV's 15.0x EV/EBITDA is more attractive than ALKS's 17.3x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $2.2B | $1712.35T | $5.9B | $5.5B | $358.4B |
| Enterprise ValueMkt cap + debt − cash | $2.2B | $1712.35T | $4.9B | $4.8B | $422.3B |
| Trailing P/EPrice ÷ TTM EPS | -8.54x | -0.76x | 24.76x | -9.97x | 85.50x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 14.28x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 17.25x | — | 14.96x |
| Price / SalesMarket cap ÷ Revenue | 1477.19x | — | 4.00x | — | 5.86x |
| Price / BookPrice ÷ Book value/share | 4.20x | 0.66x | 3.28x | 5.83x | — |
| Price / FCFMarket cap ÷ FCF | — | — | 12.28x | — | 20.12x |
Profitability & Efficiency
ALKS leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DBVT's 0.13x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs IMVT's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -41.7% | -130.2% | +8.8% | -47.1% | +62.1% |
| ROA (TTM)Return on assets | -38.9% | -89.0% | +5.4% | -44.1% | +3.1% |
| ROICReturn on invested capital | -35.2% | — | +18.9% | — | +23.9% |
| ROCEReturn on capital employed | -44.7% | -145.7% | +14.2% | -66.1% | +21.5% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 7 | 2 | 6 |
| Debt / EquityFinancial leverage | 0.00x | 0.13x | 0.04x | 0.00x | — |
| Net DebtTotal debt minus cash | -$27M | -$172M | -$1.0B | -$714M | $63.8B |
| Cash & Equiv.Liquid assets | $29M | $194M | $1.1B | $714M | $5.2B |
| Total DebtShort + long-term debt | $2M | $22M | $70M | $98,000 | $69.1B |
| Interest CoverageEBIT ÷ Interest expense | — | -189.82x | 32.30x | — | 3.28x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs CLDX's -0.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +23.4% | +4.9% | +25.3% | +5.1% | -10.1% |
| 1-Year ReturnPast 12 months | +76.2% | +110.4% | +16.5% | +96.1% | +11.3% |
| 3-Year ReturnCumulative with dividends | -0.1% | +19.7% | +14.5% | +40.9% | +50.4% |
| 5-Year ReturnCumulative with dividends | +22.0% | -69.1% | +60.9% | +62.4% | +101.3% |
| 10-Year ReturnCumulative with dividends | -43.3% | -87.0% | -11.0% | +173.6% | +295.5% |
| CAGR (3Y)Annualised 3-year return | -0.0% | +6.2% | +4.6% | +12.1% | +14.6% |
Risk & Volatility
Evenly matched — ALKS and ABBV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than CLDX's 1.73 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs DBVT's 76.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.73x | 1.26x | 1.06x | 1.37x | 0.34x |
| 52-Week HighHighest price in past year | $35.79 | $26.18 | $36.60 | $30.09 | $244.81 |
| 52-Week LowLowest price in past year | $17.85 | $7.53 | $25.17 | $13.36 | $176.57 |
| % of 52W HighCurrent price vs 52-week peak | +93.1% | +76.3% | +96.7% | +90.5% | +82.8% |
| RSI (14)Momentum oscillator 0–100 | 60.7 | 48.1 | 60.2 | 60.2 | 46.8 |
| Avg Volume (50D)Average daily shares traded | 985K | 252K | 2.3M | 1.4M | 5.8M |
Analyst Outlook
ABBV leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: CLDX as "Buy", DBVT as "Buy", ALKS as "Buy", IMVT as "Buy", ABBV as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 24.3% for ALKS (target: $44). ABBV is the only dividend payer here at 3.24% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $45.00 | $46.33 | $44.00 | $45.50 | $256.64 |
| # AnalystsCovering analysts | 19 | 15 | 28 | 23 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +3.2% |
| Dividend StreakConsecutive years of raises | — | 0 | 0 | — | 13 |
| Dividend / ShareAnnual DPS | — | — | — | — | $6.57 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.5% | 0.0% | +0.3% |
ABBV leads in 3 of 6 categories (Income & Cash Flow, Total Returns). ALKS leads in 2 (Valuation Metrics, Profitability & Efficiency). 1 tied.
CLDX vs DBVT vs ALKS vs IMVT vs ABBV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is CLDX or DBVT or ALKS or IMVT or ABBV a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -78. 6% for Celldex Therapeutics, Inc. (CLDX). Alkermes plc (ALKS) offers the better valuation at 24. 8x trailing P/E, making it the more compelling value choice. Analysts rate Celldex Therapeutics, Inc. (CLDX) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — CLDX or DBVT or ALKS or IMVT or ABBV?
On trailing P/E, Alkermes plc (ALKS) is the cheapest at 24.
8x versus AbbVie Inc. at 85. 5x.
03Which is the better long-term investment — CLDX or DBVT or ALKS or IMVT or ABBV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — CLDX or DBVT or ALKS or IMVT or ABBV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus Celldex Therapeutics, Inc. 's 1. 73β — meaning CLDX is approximately 410% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 13% for DBV Technologies S. A. — giving it more financial flexibility in a downturn.
05Which is growing faster — CLDX or DBVT or ALKS or IMVT or ABBV?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -78. 6% for Celldex Therapeutics, Inc. (CLDX). On earnings-per-share growth, the picture is similar: AbbVie Inc. grew EPS -0. 8% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ALKS leads at 9. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — CLDX or DBVT or ALKS or IMVT or ABBV?
Alkermes plc (ALKS) is the more profitable company, earning 16.
4% net margin versus -172. 5% for Celldex Therapeutics, Inc. — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -191. 6% for CLDX. At the gross margin level — before operating expenses — CLDX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is CLDX or DBVT or ALKS or IMVT or ABBV more undervalued right now?
Analyst consensus price targets imply the most upside for DBVT: 131.
8% to $46. 33.
08Which pays a better dividend — CLDX or DBVT or ALKS or IMVT or ABBV?
In this comparison, ABBV (3.
2% yield) pays a dividend. CLDX, DBVT, ALKS, IMVT do not pay a meaningful dividend and should not be held primarily for income.
09Is CLDX or DBVT or ALKS or IMVT or ABBV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Celldex Therapeutics, Inc. (CLDX) carries a higher beta of 1. 73 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABBV: +295. 5%, CLDX: -43. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between CLDX and DBVT and ALKS and IMVT and ABBV?
Both stocks operate in the null sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CLDX is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; ALKS is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock. ABBV pays a dividend while CLDX, DBVT, ALKS, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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