CMPS
COMPASS Pathways plc
Medical - Care Facilities
Market Cap$902M
5Y Perf.-73.1%
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Stock Comparison
CMPS vs SAVA
Revenue, margins, valuation, and 5-year total return — side by side.
SAVA
Cassava Sciences, Inc.
Biotechnology
Market Cap$94M
5Y Perf.+39.0%
CMPS vs SAVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | CMPS | SAVA |
|---|---|---|
| Industry | Medical - Care Facilities | Biotechnology |
| Market Cap | $902M | $94M |
| Revenue (TTM) | $0.00 | $0.00 |
| Net Income (TTM) | $-288M | $-106M |
| Total Debt | $21M | $0.00 |
| Cash & Equiv. | $150M | $129M |
CMPS vs SAVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
CMPS
SAVA
| Stock | Sep 20 | May 26 | Return |
|---|---|---|---|
| COMPASS Pathways plc (CMPS) | 100 | 26.9 | -73.1% |
| Cassava Sciences, I… (SAVA) | 100 | 139.0 | +39.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CMPS vs SAVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: CMPS leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. Cassava Sciences, Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
CMPS
COMPASS Pathways plc
The Income Pick
CMPS carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 1.33
- Lower volatility, beta 1.33, current ratio 0.77x
- Beta 1.33, current ratio 0.77x
Best for: income & stability and sleep-well-at-night
SAVA
Cassava Sciences, Inc.
The Growth Play
SAVA is the clearest fit if your priority is growth exposure and long-term compounding.
- EPS growth 77.6%
- -19.5% 10Y total return vs CMPS's -67.6%
- 5.4% margin vs CMPS's 1.3%
Best for: growth exposure and long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | CMPS | -85.7% revenue growth vs SAVA's -5.4% |
| Quality / Margins | SAVA | 5.4% margin vs CMPS's 1.3% |
| Stability / Safety | CMPS | Beta 1.33 vs SAVA's 2.02 |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | CMPS | +151.1% vs SAVA's +25.3% |
| Efficiency (ROA) | SAVA | -75.3% ROA vs CMPS's -106.8% |
CMPS vs SAVA — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLSAVALAGGINGCMPS
CMPSCOMPASS Pathways plc
2leads
SAVACassava Sciences, Inc.
3leads
6 Total Categories
CATEGORYLEADERvs CMPSMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
SAVA1/1
Valuation MetricsMultiples, price ratios, and targets
SAVA1/1
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
SAVA4/5
Total Returns1Y, 3Y, 5Y total returns with dividends
CMPS4/6
Risk & VolatilityBeta, volatility, and downside exposure
CMPS2/2
Analyst OutlookRatings, price targets, and dividends
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Income & Cash Flow (Last 12 Months)
SAVA leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
CMPS and SAVA operate at a comparable scale, with $0 and $0 in trailing revenue.
| Metric | CMPSCOMPASS Pathways … | SAVACassava Sciences,… |
|---|---|---|
| RevenueTrailing 12 months | $0 | $0 |
| EBITDAEarnings before interest/tax | -$179M | -$110M |
| Net IncomeAfter-tax profit | -$288M | -$106M |
| Free Cash FlowCash after capex | -$157M | -$84M |
| Gross MarginGross profit ÷ Revenue | — | — |
| Operating MarginEBIT ÷ Revenue | — | — |
| Net MarginNet income ÷ Revenue | — | — |
| FCF MarginFCF ÷ Revenue | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | -58.7% | +62.1% |
SAVA leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
SAVA leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
| Metric | CMPSCOMPASS Pathways … | SAVACassava Sciences,… |
|---|---|---|
| Market CapShares × price | $902M | $94M |
| Enterprise ValueMkt cap + debt − cash | $774M | -$34M |
| Trailing P/EPrice ÷ TTM EPS | -3.05x | -3.76x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — |
| Price / BookPrice ÷ Book value/share | — | 0.63x |
| Price / FCFMarket cap ÷ FCF | — | — |
SAVA leads this category, winning 1 of 1 comparable metric.
Profitability & Efficiency
SAVA leads this category, winning 4 of 5 comparable metrics.
Profitability & Efficiency
SAVA delivers a -95.8% return on equity — every $100 of shareholder capital generates $-96 in annual profit, vs $-3 for CMPS.
| Metric | CMPSCOMPASS Pathways … | SAVACassava Sciences,… |
|---|---|---|
| ROE (TTM)Return on equity | -3.4% | -95.8% |
| ROA (TTM)Return on assets | -106.8% | -75.3% |
| ROICReturn on invested capital | — | -6.3% |
| ROCEReturn on capital employed | -2.5% | -99.9% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 |
| Debt / EquityFinancial leverage | — | — |
| Net DebtTotal debt minus cash | -$129M | -$129M |
| Cash & Equiv.Liquid assets | $150M | $129M |
| Total DebtShort + long-term debt | $21M | $0 |
| Interest CoverageEBIT ÷ Interest expense | -52.40x | — |
SAVA leads this category, winning 4 of 5 comparable metrics.
Total Returns (Dividends Reinvested)
CMPS leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in SAVA five years ago would be worth $3,302 today (with dividends reinvested), compared to $2,756 for CMPS. Over the past 12 months, CMPS leads with a +151.1% total return vs SAVA's +25.3%. The 3-year compound annual growth rate (CAGR) favors CMPS at 3.5% vs SAVA's -16.0% — a key indicator of consistent wealth creation.
| Metric | CMPSCOMPASS Pathways … | SAVACassava Sciences,… |
|---|---|---|
| YTD ReturnYear-to-date | +43.4% | -6.5% |
| 1-Year ReturnPast 12 months | +151.1% | +25.3% |
| 3-Year ReturnCumulative with dividends | +11.0% | -40.8% |
| 5-Year ReturnCumulative with dividends | -72.4% | -67.0% |
| 10-Year ReturnCumulative with dividends | -67.6% | -19.5% |
| CAGR (3Y)Annualised 3-year return | +3.5% | -16.0% |
CMPS leads this category, winning 4 of 6 comparable metrics.
Risk & Volatility
CMPS leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
CMPS is the less volatile stock with a 1.33 beta — it tends to amplify market swings less than SAVA's 2.02 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CMPS currently trades 92.0% from its 52-week high vs SAVA's 39.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | CMPSCOMPASS Pathways … | SAVACassava Sciences,… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.33x | 2.02x |
| 52-Week HighHighest price in past year | $10.21 | $4.98 |
| 52-Week LowLowest price in past year | $2.25 | $1.51 |
| % of 52W HighCurrent price vs 52-week peak | +92.0% | +39.3% |
| RSI (14)Momentum oscillator 0–100 | 68.1 | 46.8 |
| Avg Volume (50D)Average daily shares traded | 3.7M | 712K |
CMPS leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates CMPS as "Buy" and SAVA as "Buy".
| Metric | CMPSCOMPASS Pathways … | SAVACassava Sciences,… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $17.83 | — |
| # AnalystsCovering analysts | 13 | 12 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | 1 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
SAVA leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CMPS leads in 2 (Total Returns, Risk & Volatility).
Best OverallCassava Sciences, Inc. (SAVA)Leads 3 of 6 categories
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CMPS vs SAVA: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is CMPS or SAVA a better buy right now?
Analysts rate COMPASS Pathways plc (CMPS) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison.
The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CMPS or SAVA?
Over the past 5 years, Cassava Sciences, Inc.
(SAVA) delivered a total return of -67. 0%, compared to -72. 4% for COMPASS Pathways plc (CMPS). Over 10 years, the gap is even starker: SAVA returned -19. 5% versus CMPS's -67. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CMPS or SAVA?
By beta (market sensitivity over 5 years), COMPASS Pathways plc (CMPS) is the lower-risk stock at 1.
33β versus Cassava Sciences, Inc. 's 2. 02β — meaning SAVA is approximately 52% more volatile than CMPS relative to the S&P 500.
04Which is growing faster — CMPS or SAVA?
On earnings-per-share growth, the picture is similar: Cassava Sciences, Inc.
grew EPS 77. 6% year-over-year, compared to -33. 9% for COMPASS Pathways plc. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CMPS or SAVA?
COMPASS Pathways plc (CMPS) is the more profitable company, earning 0.
0% net margin versus 0. 0% for Cassava Sciences, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CMPS leads at 0. 0% versus 0. 0% for SAVA. At the gross margin level — before operating expenses — CMPS leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CMPS or SAVA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CMPS or SAVA better for a retirement portfolio?
For long-horizon retirement investors, COMPASS Pathways plc (CMPS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding.
Cassava Sciences, Inc. (SAVA) carries a higher beta of 2. 02 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CMPS: -67. 6%, SAVA: -19. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CMPS and SAVA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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