Biotechnology
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CNTB vs DAWN vs IMVT vs KYMR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
CNTB vs DAWN vs IMVT vs KYMR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $130M | $2.22B | $5.53B | $6.91B |
| Revenue (TTM) | $26M | $158M | $0.00 | $51M |
| Net Income (TTM) | $-57M | $-107M | $-464M | $-315M |
| Gross Margin | 95.6% | 89.1% | — | 33.2% |
| Operating Margin | -223.4% | -80.8% | — | -7.0% |
| Total Debt | $178K | $3M | $98K | $82M |
| Cash & Equiv. | $78M | $197M | $714M | $357M |
CNTB vs DAWN vs IMVT vs KYMR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 21 | May 26 | Return |
|---|---|---|---|
| Connect Biopharma H… (CNTB) | 100 | 15.7 | -84.3% |
| Day One Biopharmace… (DAWN) | 100 | 90.5 | -9.5% |
| Immunovant, Inc. (IMVT) | 100 | 179.6 | +79.6% |
| Kymera Therapeutics… (KYMR) | 100 | 176.0 | +76.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CNTB vs DAWN vs IMVT vs KYMR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CNTB is the #2 pick in this set and the best alternative if growth is your priority.
- 72.2% revenue growth vs IMVT's -21.3%
DAWN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.35
- Rev growth 20.6%, EPS growth -2.0%
- Lower volatility, beta 0.35, Low D/E 0.6%, current ratio 8.02x
- Beta 0.35, current ratio 8.02x
IMVT is the clearest fit if your priority is long-term compounding.
- 173.6% 10Y total return vs KYMR's 154.4%
- 3.2% margin vs KYMR's -6.1%
KYMR lags the leaders in this set but could rank higher in a more targeted comparison.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 72.2% revenue growth vs IMVT's -21.3% | |
| Quality / Margins | 3.2% margin vs KYMR's -6.1% | |
| Stability / Safety | Beta 0.35 vs IMVT's 1.37 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +241.7% vs IMVT's +96.1% | |
| Efficiency (ROA) | -20.7% ROA vs CNTB's -69.4%, ROIC -30.5% vs -338.2% |
CNTB vs DAWN vs IMVT vs KYMR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
CNTB vs DAWN vs IMVT vs KYMR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
DAWN leads in 1 of 6 categories
CNTB leads 1 • IMVT leads 1 • KYMR leads 1 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
DAWN leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
DAWN and IMVT operate at a comparable scale, with $158M and $0 in trailing revenue. Profitability is closely matched — net margins range from -67.8% (DAWN) to -6.1% (KYMR). On growth, DAWN holds the edge at +83.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $26M | $158M | $0 | $51M |
| EBITDAEarnings before interest/tax | -$57M | -$124M | -$487M | -$352M |
| Net IncomeAfter-tax profit | -$57M | -$107M | -$464M | -$315M |
| Free Cash FlowCash after capex | -$54M | -$108M | -$423M | -$244M |
| Gross MarginGross profit ÷ Revenue | +95.6% | +89.1% | — | +33.2% |
| Operating MarginEBIT ÷ Revenue | -2.2% | -80.8% | — | -7.0% |
| Net MarginNet income ÷ Revenue | -2.2% | -67.8% | — | -6.1% |
| FCF MarginFCF ÷ Revenue | -2.1% | -68.0% | — | -4.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | -99.8% | +83.9% | — | +55.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.6% | +70.0% | +19.7% | +13.4% |
Valuation Metrics
CNTB leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $130M | $2.2B | $5.5B | $6.9B |
| Enterprise ValueMkt cap + debt − cash | $51M | $2.0B | $4.8B | $6.6B |
| Trailing P/EPrice ÷ TTM EPS | -8.32x | -20.70x | -9.97x | -22.93x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 4.97x | 14.06x | — | 176.26x |
| Price / BookPrice ÷ Book value/share | 1.40x | 5.05x | 5.83x | 4.52x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
IMVT leads this category, winning 3 of 9 comparable metrics.
Profitability & Efficiency
DAWN delivers a -23.4% return on equity — every $100 of shareholder capital generates $-23 in annual profit, vs $-80 for CNTB. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KYMR's 0.05x. On the Piotroski fundamental quality scale (0–9), CNTB scores 5/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -80.4% | -23.4% | -47.1% | -25.0% |
| ROA (TTM)Return on assets | -69.4% | -20.7% | -44.1% | -22.3% |
| ROICReturn on invested capital | -3.4% | -30.5% | — | -24.9% |
| ROCEReturn on capital employed | -23.2% | -26.7% | -66.1% | -27.2% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 2 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.01x | 0.00x | 0.05x |
| Net DebtTotal debt minus cash | -$78M | -$194M | -$714M | -$275M |
| Cash & Equiv.Liquid assets | $78M | $197M | $714M | $357M |
| Total DebtShort + long-term debt | $178,000 | $3M | $98,000 | $82M |
| Interest CoverageEBIT ÷ Interest expense | -5993.94x | — | — | -2119.53x |
Total Returns (Dividends Reinvested)
KYMR leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $1,500 for CNTB. Over the past 12 months, DAWN leads with a +241.7% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs IMVT's 12.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -7.5% | +143.3% | +5.1% | +16.3% |
| 1-Year ReturnPast 12 months | +191.3% | +241.7% | +96.1% | +190.7% |
| 3-Year ReturnCumulative with dividends | +97.5% | +65.1% | +40.9% | +205.1% |
| 5-Year ReturnCumulative with dividends | -85.0% | -8.4% | +62.4% | +92.1% |
| 10-Year ReturnCumulative with dividends | -87.4% | -8.4% | +173.6% | +154.4% |
| CAGR (3Y)Annualised 3-year return | +25.5% | +18.2% | +12.1% | +45.0% |
Risk & Volatility
Evenly matched — CNTB and DAWN each lead in 1 of 2 comparable metrics.
Risk & Volatility
CNTB is the less volatile stock with a -0.14 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DAWN currently trades 100.0% from its 52-week high vs CNTB's 61.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.14x | 0.35x | 1.37x | 1.15x |
| 52-Week HighHighest price in past year | $3.82 | $21.53 | $30.09 | $103.00 |
| 52-Week LowLowest price in past year | $0.70 | $5.64 | $13.36 | $28.06 |
| % of 52W HighCurrent price vs 52-week peak | +61.0% | +100.0% | +90.5% | +82.2% |
| RSI (14)Momentum oscillator 0–100 | 42.8 | 80.3 | 60.2 | 54.1 |
| Avg Volume (50D)Average daily shares traded | 272K | 4.9M | 1.4M | 602K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: CNTB as "Buy", DAWN as "Buy", IMVT as "Buy", KYMR as "Buy". Consensus price targets imply 286.3% upside for CNTB (target: $9) vs 10.3% for DAWN (target: $24).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $9.00 | $23.75 | $45.50 | $117.06 |
| # AnalystsCovering analysts | 5 | 12 | 23 | 26 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
DAWN leads in 1 of 6 categories (Income & Cash Flow). CNTB leads in 1 (Valuation Metrics). 1 tied.
CNTB vs DAWN vs IMVT vs KYMR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is CNTB or DAWN or IMVT or KYMR a better buy right now?
For growth investors, Day One Biopharmaceuticals, Inc.
(DAWN) is the stronger pick with 20. 6% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Analysts rate Connect Biopharma Holdings Limited (CNTB) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CNTB or DAWN or IMVT or KYMR?
Over the past 5 years, Kymera Therapeutics, Inc.
(KYMR) delivered a total return of +92. 1%, compared to -85. 0% for Connect Biopharma Holdings Limited (CNTB). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus CNTB's -87. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CNTB or DAWN or IMVT or KYMR?
By beta (market sensitivity over 5 years), Connect Biopharma Holdings Limited (CNTB) is the lower-risk stock at -0.
14β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately -1093% more volatile than CNTB relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 5% for Kymera Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CNTB or DAWN or IMVT or KYMR?
By revenue growth (latest reported year), Day One Biopharmaceuticals, Inc.
(DAWN) is pulling ahead at 20. 6% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Connect Biopharma Holdings Limited grew EPS 74. 1% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CNTB or DAWN or IMVT or KYMR?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — CNTB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CNTB or DAWN or IMVT or KYMR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CNTB or DAWN or IMVT or KYMR better for a retirement portfolio?
For long-horizon retirement investors, Connect Biopharma Holdings Limited (CNTB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
14)). Both have compounded well over 10 years (CNTB: -87. 4%, IMVT: +173. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CNTB and DAWN and IMVT and KYMR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CNTB is a small-cap quality compounder stock; DAWN is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; KYMR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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