CNTB
Connect Biopharma Holdings Limited
Biotechnology
Market Cap$130M
5Y Perf.-89.4%
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Stock Comparison
CNTB vs RXST
Revenue, margins, valuation, and 5-year total return — side by side.
RXST
RxSight, Inc.
Medical - Devices
Market Cap$239M
5Y Perf.-63.8%
CNTB vs RXST — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | CNTB | RXST |
|---|---|---|
| Industry | Biotechnology | Medical - Devices |
| Market Cap | $130M | $239M |
| Revenue (TTM) | $26M | $127M |
| Net Income (TTM) | $-57M | $-47M |
| Gross Margin | 95.6% | 77.0% |
| Operating Margin | -223.4% | -43.4% |
| Total Debt | $178K | $11M |
| Cash & Equiv. | $78M | $20M |
CNTB vs RXST — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
CNTB
RXST
| Stock | Jul 21 | May 26 | Return |
|---|---|---|---|
| Connect Biopharma H… (CNTB) | 100 | 10.6 | -89.4% |
| RxSight, Inc. (RXST) | 100 | 36.3 | -63.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CNTB vs RXST
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: CNTB leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. RxSight, Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
CNTB
Connect Biopharma Holdings Limited
The Growth Play
CNTB carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.
- EPS growth 74.1%
- Lower volatility, beta -0.14, Low D/E 0.2%, current ratio 11.46x
- Beta -0.14, current ratio 11.46x
Best for: growth exposure and sleep-well-at-night
RXST
RxSight, Inc.
The Long-Run Compounder
RXST is the clearest fit if your priority is long-term compounding.
- -63.7% 10Y total return vs CNTB's -87.4%
- -36.6% margin vs CNTB's -220.1%
- -15.1% ROA vs CNTB's -69.4%, ROIC -13.3% vs -338.2%
Best for: long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | CNTB | 72.2% revenue growth vs RXST's -3.9% |
| Quality / Margins | RXST | -36.6% margin vs CNTB's -220.1% |
| Stability / Safety | CNTB | Lower D/E ratio (0.2% vs 4.0%) |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | CNTB | +191.3% vs RXST's -61.1% |
| Efficiency (ROA) | RXST | -15.1% ROA vs CNTB's -69.4%, ROIC -13.3% vs -338.2% |
CNTB vs RXST — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
FY 2024
FY 2025
CNTB vs RXST — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLRXSTLAGGINGCNTB
CNTBConnect Biopharma Hol…
2leads
RXSTRxSight, Inc.
3leads
6 Total Categories
CATEGORYLEADERvs CNTBMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
RXST5/6
Valuation MetricsMultiples, price ratios, and targets
RXST2/3
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
RXST5/9
Total Returns1Y, 3Y, 5Y total returns with dividends
CNTB4/6
Risk & VolatilityBeta, volatility, and downside exposure
CNTB2/2
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
RXST leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RXST is the larger business by revenue, generating $127M annually — 4.9x CNTB's $26M. Profitability is closely matched — net margins range from -36.6% (RXST) to -2.2% (CNTB). On growth, RXST holds the edge at -18.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | CNTBConnect Biopharma… | RXSTRxSight, Inc. |
|---|---|---|
| RevenueTrailing 12 months | $26M | $127M |
| EBITDAEarnings before interest/tax | -$57M | -$57M |
| Net IncomeAfter-tax profit | -$57M | -$47M |
| Free Cash FlowCash after capex | -$54M | -$2M |
| Gross MarginGross profit ÷ Revenue | +95.6% | +77.0% |
| Operating MarginEBIT ÷ Revenue | -2.2% | -43.4% |
| Net MarginNet income ÷ Revenue | -2.2% | -36.6% |
| FCF MarginFCF ÷ Revenue | -2.1% | -1.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -99.8% | -18.5% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.6% | -90.0% |
RXST leads this category, winning 5 of 6 comparable metrics.
Valuation Metrics
RXST leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | CNTBConnect Biopharma… | RXSTRxSight, Inc. |
|---|---|---|
| Market CapShares × price | $130M | $239M |
| Enterprise ValueMkt cap + debt − cash | $51M | $230M |
| Trailing P/EPrice ÷ TTM EPS | -8.32x | -6.11x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 4.97x | 1.78x |
| Price / BookPrice ÷ Book value/share | 1.40x | 0.87x |
| Price / FCFMarket cap ÷ FCF | — | — |
RXST leads this category, winning 2 of 3 comparable metrics.
Profitability & Efficiency
RXST leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
RXST delivers a -17.0% return on equity — every $100 of shareholder capital generates $-17 in annual profit, vs $-80 for CNTB. CNTB carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to RXST's 0.04x. On the Piotroski fundamental quality scale (0–9), CNTB scores 5/9 vs RXST's 3/9, reflecting solid financial health.
| Metric | CNTBConnect Biopharma… | RXSTRxSight, Inc. |
|---|---|---|
| ROE (TTM)Return on equity | -80.4% | -17.0% |
| ROA (TTM)Return on assets | -69.4% | -15.1% |
| ROICReturn on invested capital | -3.4% | -13.3% |
| ROCEReturn on capital employed | -23.2% | -16.7% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 3 |
| Debt / EquityFinancial leverage | 0.00x | 0.04x |
| Net DebtTotal debt minus cash | -$78M | -$9M |
| Cash & Equiv.Liquid assets | $78M | $20M |
| Total DebtShort + long-term debt | $178,000 | $11M |
| Interest CoverageEBIT ÷ Interest expense | -5993.94x | -4852.10x |
RXST leads this category, winning 5 of 9 comparable metrics.
Total Returns (Dividends Reinvested)
CNTB leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in RXST five years ago would be worth $3,625 today (with dividends reinvested), compared to $1,500 for CNTB. Over the past 12 months, CNTB leads with a +191.3% total return vs RXST's -61.1%. The 3-year compound annual growth rate (CAGR) favors CNTB at 25.5% vs RXST's -33.1% — a key indicator of consistent wealth creation.
| Metric | CNTBConnect Biopharma… | RXSTRxSight, Inc. |
|---|---|---|
| YTD ReturnYear-to-date | -7.5% | -44.1% |
| 1-Year ReturnPast 12 months | +191.3% | -61.1% |
| 3-Year ReturnCumulative with dividends | +97.5% | -70.1% |
| 5-Year ReturnCumulative with dividends | -85.0% | -63.7% |
| 10-Year ReturnCumulative with dividends | -87.4% | -63.7% |
| CAGR (3Y)Annualised 3-year return | +25.5% | -33.1% |
CNTB leads this category, winning 4 of 6 comparable metrics.
Risk & Volatility
CNTB leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
CNTB is the less volatile stock with a -0.14 beta — it tends to amplify market swings less than RXST's 1.73 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CNTB currently trades 61.0% from its 52-week high vs RXST's 34.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | CNTBConnect Biopharma… | RXSTRxSight, Inc. |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.14x | 1.73x |
| 52-Week HighHighest price in past year | $3.82 | $16.74 |
| 52-Week LowLowest price in past year | $0.70 | $5.30 |
| % of 52W HighCurrent price vs 52-week peak | +61.0% | +34.6% |
| RSI (14)Momentum oscillator 0–100 | 42.8 | 43.5 |
| Avg Volume (50D)Average daily shares traded | 272K | 741K |
CNTB leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates CNTB as "Buy" and RXST as "Hold". Consensus price targets imply 286.3% upside for CNTB (target: $9) vs 85.3% for RXST (target: $11).
| Metric | CNTBConnect Biopharma… | RXSTRxSight, Inc. |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold |
| Price TargetConsensus 12-month target | $9.00 | $10.75 |
| # AnalystsCovering analysts | 5 | 12 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
RXST leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CNTB leads in 2 (Total Returns, Risk & Volatility).
Best OverallRxSight, Inc. (RXST)Leads 3 of 6 categories
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CNTB vs RXST: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is CNTB or RXST a better buy right now?
Analysts rate Connect Biopharma Holdings Limited (CNTB) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison.
The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CNTB or RXST?
Over the past 5 years, RxSight, Inc.
(RXST) delivered a total return of -63. 7%, compared to -85. 0% for Connect Biopharma Holdings Limited (CNTB). Over 10 years, the gap is even starker: RXST returned -63. 7% versus CNTB's -87. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CNTB or RXST?
By beta (market sensitivity over 5 years), Connect Biopharma Holdings Limited (CNTB) is the lower-risk stock at -0.
14β versus RxSight, Inc. 's 1. 73β — meaning RXST is approximately -1346% more volatile than CNTB relative to the S&P 500. On balance sheet safety, Connect Biopharma Holdings Limited (CNTB) carries a lower debt/equity ratio of 0% versus 4% for RxSight, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CNTB or RXST?
On earnings-per-share growth, the picture is similar: Connect Biopharma Holdings Limited grew EPS 74.
1% year-over-year, compared to -33. 8% for RxSight, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CNTB or RXST?
RxSight, Inc.
(RXST) is the more profitable company, earning -29. 0% net margin versus -60. 0% for Connect Biopharma Holdings Limited — meaning it keeps -29. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RXST leads at -35. 8% versus -86. 2% for CNTB. At the gross margin level — before operating expenses — CNTB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CNTB or RXST?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CNTB or RXST better for a retirement portfolio?
For long-horizon retirement investors, Connect Biopharma Holdings Limited (CNTB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
14)). RxSight, Inc. (RXST) carries a higher beta of 1. 73 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CNTB: -87. 4%, RXST: -63. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CNTB and RXST?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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