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Stock Comparison

COSM vs PHVS vs HROW vs KALV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
COSM
Cosmos Health Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$11M
5Y Perf.-92.7%
PHVS
Pharvaris N.V.

Biotechnology

HealthcareNASDAQ • NL
Market Cap$1.93B
5Y Perf.-21.9%
HROW
Harrow Health, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.45B
5Y Perf.+409.1%
KALV
KalVista Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.37B
5Y Perf.-18.7%

COSM vs PHVS vs HROW vs KALV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
COSM logoCOSM
PHVS logoPHVS
HROW logoHROW
KALV logoKALV
IndustryDrug Manufacturers - Specialty & GenericBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnology
Market Cap$11M$1.93B$1.45B$1.37B
Revenue (TTM)$60M$0.00$272M$15M
Net Income (TTM)$-19M$-166M$-5M$-210M
Gross Margin11.4%75.1%-17.2%
Operating Margin-23.9%11.2%-13.4%
Forward P/E82.9x
Total Debt$12M$861K$252M$6M
Cash & Equiv.$315K$281M$73M$99M

COSM vs PHVS vs HROW vs KALVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

COSM
PHVS
HROW
KALV
StockFeb 21May 26Return
Cosmos Health Inc. (COSM)1007.3-92.7%
Pharvaris N.V. (PHVS)10078.1-21.9%
Harrow Health, Inc. (HROW)100509.1+409.1%
KalVista Pharmaceut… (KALV)10081.3-18.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: COSM vs PHVS vs HROW vs KALV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HROW and KALV are tied at the top with 2 categories each — the right choice depends on your priorities. KalVista Pharmaceuticals, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. COSM and PHVS also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
COSM
Cosmos Health Inc.
The Income Pick

COSM is the clearest fit if your priority is income & stability.

  • Dividend streak 1 yrs, beta 1.72, yield 92.4%
  • 92.4% yield; 1-year raise streak; the other 3 pay no meaningful dividend
Best for: income & stability
PHVS
Pharvaris N.V.
The Defensive Pick

PHVS is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 1.02, Low D/E 0.3%, current ratio 12.60x
  • 1.9% margin vs KALV's -13.9%
Best for: sleep-well-at-night
HROW
Harrow Health, Inc.
The Growth Play

HROW carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 36.4%, EPS growth 71.4%, 3Y rev CAGR 45.4%
  • 9.1% 10Y total return vs KALV's 154.5%
  • 36.4% revenue growth vs KALV's -34.5%
  • -1.4% ROA vs KALV's -77.7%, ROIC 9.5% vs -152.3%
Best for: growth exposure and long-term compounding
KALV
KalVista Pharmaceuticals, Inc.
The Defensive Pick

KALV is the #2 pick in this set and the best alternative if defensive is your priority.

  • Beta 0.82, current ratio 5.35x
  • Beta 0.82 vs HROW's 2.13, lower leverage
  • +118.1% vs COSM's -17.0%
Best for: defensive
See the full category breakdown
CategoryWinnerWhy
GrowthHROW logoHROW36.4% revenue growth vs KALV's -34.5%
Quality / MarginsPHVS logoPHVS1.9% margin vs KALV's -13.9%
Stability / SafetyKALV logoKALVBeta 0.82 vs HROW's 2.13, lower leverage
DividendsCOSM logoCOSM92.4% yield; 1-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)KALV logoKALV+118.1% vs COSM's -17.0%
Efficiency (ROA)HROW logoHROW-1.4% ROA vs KALV's -77.7%, ROIC 9.5% vs -152.3%

COSM vs PHVS vs HROW vs KALV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

COSMCosmos Health Inc.
FY 2024
Pharma manufacturing
100.0%$865,373
PHVSPharvaris N.V.

Segment breakdown not available.

HROWHarrow Health, Inc.
FY 2025
Product Sales Net
99.9%$272M
Other Revenues
0.1%$394,000
KALVKalVista Pharmaceuticals, Inc.

Segment breakdown not available.

COSM vs PHVS vs HROW vs KALV — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCOSMLAGGINGPHVS

Income & Cash Flow (Last 12 Months)

HROW leads this category, winning 4 of 6 comparable metrics.

HROW and PHVS operate at a comparable scale, with $272M and $0 in trailing revenue. HROW is the more profitable business, keeping -1.9% of every revenue dollar as net income compared to KALV's -13.9%. On growth, COSM holds the edge at +37.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCOSM logoCOSMCosmos Health Inc.PHVS logoPHVSPharvaris N.V.HROW logoHROWHarrow Health, In…KALV logoKALVKalVista Pharmace…
RevenueTrailing 12 months$60M$0$272M$15M
EBITDAEarnings before interest/tax-$13M-$86M$59M-$202M
Net IncomeAfter-tax profit-$19M-$166M-$5M-$210M
Free Cash FlowCash after capex-$10M-$134M$73M-$160M
Gross MarginGross profit ÷ Revenue+11.4%+75.1%-17.2%
Operating MarginEBIT ÷ Revenue-23.9%+11.2%-13.4%
Net MarginNet income ÷ Revenue-31.0%-1.9%-13.9%
FCF MarginFCF ÷ Revenue-17.2%+26.8%-10.6%
Rev. Growth (YoY)Latest quarter vs prior year+37.9%+33.3%
EPS Growth (YoY)Latest quarter vs prior year+62.2%+22.1%-5.3%-1.1%
HROW leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

COSM leads this category, winning 2 of 3 comparable metrics.
MetricCOSM logoCOSMCosmos Health Inc.PHVS logoPHVSPharvaris N.V.HROW logoHROWHarrow Health, In…KALV logoKALVKalVista Pharmace…
Market CapShares × price$11M$1.9B$1.5B$1.4B
Enterprise ValueMkt cap + debt − cash$23M$1.6B$1.6B$1.3B
Trailing P/EPrice ÷ TTM EPS-0.30x-10.18x-278.93x-7.24x
Forward P/EPrice ÷ next-FY EPS est.82.86x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue0.20x5.34x
Price / BookPrice ÷ Book value/share0.27x5.10x27.56x13.91x
Price / FCFMarket cap ÷ FCF
COSM leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

HROW leads this category, winning 6 of 9 comparable metrics.

HROW delivers a -10.1% return on equity — every $100 of shareholder capital generates $-10 in annual profit, vs $-3 for KALV. PHVS carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to HROW's 4.84x. On the Piotroski fundamental quality scale (0–9), HROW scores 4/9 vs PHVS's 1/9, reflecting mixed financial health.

MetricCOSM logoCOSMCosmos Health Inc.PHVS logoPHVSPharvaris N.V.HROW logoHROWHarrow Health, In…KALV logoKALVKalVista Pharmace…
ROE (TTM)Return on equity-80.1%-53.2%-10.1%-2.8%
ROA (TTM)Return on assets-26.7%-49.0%-1.4%-77.7%
ROICReturn on invested capital-28.9%+9.5%-152.3%
ROCEReturn on capital employed-44.3%-44.7%+10.2%-89.9%
Piotroski ScoreFundamental quality 0–93142
Debt / EquityFinancial leverage0.48x0.00x4.84x0.07x
Net DebtTotal debt minus cash$12M-$280M$179M-$92M
Cash & Equiv.Liquid assets$315,105$281M$73M$99M
Total DebtShort + long-term debt$12M$861,470$252M$6M
Interest CoverageEBIT ÷ Interest expense-9.42x0.53x-13.75x
HROW leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — PHVS and HROW and KALV each lead in 2 of 6 comparable metrics.

A $10,000 investment in HROW five years ago would be worth $47,797 today (with dividends reinvested), compared to $547 for COSM. Over the past 12 months, KALV leads with a +118.1% total return vs COSM's -17.0%. The 3-year compound annual growth rate (CAGR) favors PHVS at 47.4% vs COSM's -52.8% — a key indicator of consistent wealth creation.

MetricCOSM logoCOSMCosmos Health Inc.PHVS logoPHVSPharvaris N.V.HROW logoHROWHarrow Health, In…KALV logoKALVKalVista Pharmace…
YTD ReturnYear-to-date-32.0%+12.1%-21.8%+72.8%
1-Year ReturnPast 12 months-17.0%+73.6%+58.8%+118.1%
3-Year ReturnCumulative with dividends-89.5%+220.5%+43.0%+180.1%
5-Year ReturnCumulative with dividends-94.5%+31.2%+378.0%+5.9%
10-Year ReturnCumulative with dividends+37.8%+2.3%+914.3%+154.5%
CAGR (3Y)Annualised 3-year return-52.8%+47.4%+12.7%+41.0%
Evenly matched — PHVS and HROW and KALV each lead in 2 of 6 comparable metrics.

Risk & Volatility

KALV leads this category, winning 2 of 2 comparable metrics.

KALV is the less volatile stock with a 0.82 beta — it tends to amplify market swings less than HROW's 2.13 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KALV currently trades 99.5% from its 52-week high vs COSM's 26.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCOSM logoCOSMCosmos Health Inc.PHVS logoPHVSPharvaris N.V.HROW logoHROWHarrow Health, In…KALV logoKALVKalVista Pharmace…
Beta (5Y)Sensitivity to S&P 5001.72x1.02x2.13x0.82x
52-Week HighHighest price in past year$1.32$31.12$54.85$26.84
52-Week LowLowest price in past year$0.28$14.59$21.12$9.83
% of 52W HighCurrent price vs 52-week peak+26.5%+95.4%+71.2%+99.5%
RSI (14)Momentum oscillator 0–10048.657.254.675.4
Avg Volume (50D)Average daily shares traded793K227K733K3.0M
KALV leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

COSM leads this category, winning 1 of 1 comparable metric.

Analyst consensus: PHVS as "Buy", HROW as "Buy", KALV as "Buy". Consensus price targets imply 93.8% upside for HROW (target: $76) vs 6.7% for KALV (target: $29). COSM is the only dividend payer here at 92.44% yield — a key consideration for income-focused portfolios.

MetricCOSM logoCOSMCosmos Health Inc.PHVS logoPHVSPharvaris N.V.HROW logoHROWHarrow Health, In…KALV logoKALVKalVista Pharmace…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$43.67$75.67$28.50
# AnalystsCovering analysts111013
Dividend YieldAnnual dividend ÷ price+92.4%
Dividend StreakConsecutive years of raises10
Dividend / ShareAnnual DPS$0.32
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
COSM leads this category, winning 1 of 1 comparable metric.
Key Takeaway

HROW leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). COSM leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.

Best OverallCosmos Health Inc. (COSM)Leads 2 of 6 categories
Loading custom metrics...

COSM vs PHVS vs HROW vs KALV: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is COSM or PHVS or HROW or KALV a better buy right now?

For growth investors, Harrow Health, Inc.

(HROW) is the stronger pick with 36. 4% revenue growth year-over-year, versus 2. 0% for Cosmos Health Inc. (COSM). Analysts rate Pharvaris N. V. (PHVS) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — COSM or PHVS or HROW or KALV?

Over the past 5 years, Harrow Health, Inc.

(HROW) delivered a total return of +378. 0%, compared to -94. 5% for Cosmos Health Inc. (COSM). Over 10 years, the gap is even starker: HROW returned +914. 3% versus PHVS's +2. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — COSM or PHVS or HROW or KALV?

By beta (market sensitivity over 5 years), KalVista Pharmaceuticals, Inc.

(KALV) is the lower-risk stock at 0. 82β versus Harrow Health, Inc. 's 2. 13β — meaning HROW is approximately 158% more volatile than KALV relative to the S&P 500. On balance sheet safety, Pharvaris N. V. (PHVS) carries a lower debt/equity ratio of 0% versus 5% for Harrow Health, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — COSM or PHVS or HROW or KALV?

By revenue growth (latest reported year), Harrow Health, Inc.

(HROW) is pulling ahead at 36. 4% versus 2. 0% for Cosmos Health Inc. (COSM). On earnings-per-share growth, the picture is similar: Harrow Health, Inc. grew EPS 71. 4% year-over-year, compared to -7. 3% for KalVista Pharmaceuticals, Inc.. Over a 3-year CAGR, HROW leads at 45. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — COSM or PHVS or HROW or KALV?

Pharvaris N.

V. (PHVS) is the more profitable company, earning 0. 0% net margin versus -1391. 1% for KalVista Pharmaceuticals, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HROW leads at 11. 2% versus -1343. 0% for KALV. At the gross margin level — before operating expenses — HROW leads at 75. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is COSM or PHVS or HROW or KALV more undervalued right now?

Analyst consensus price targets imply the most upside for HROW: 93.

8% to $75. 67.

07

Which pays a better dividend — COSM or PHVS or HROW or KALV?

In this comparison, COSM (92.

4% yield) pays a dividend. PHVS, HROW, KALV do not pay a meaningful dividend and should not be held primarily for income.

08

Is COSM or PHVS or HROW or KALV better for a retirement portfolio?

For long-horizon retirement investors, KalVista Pharmaceuticals, Inc.

(KALV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 82), +154. 5% 10Y return). Harrow Health, Inc. (HROW) carries a higher beta of 2. 13 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KALV: +154. 5%, HROW: +914. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between COSM and PHVS and HROW and KALV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: COSM is a small-cap income-oriented stock; PHVS is a small-cap quality compounder stock; HROW is a small-cap high-growth stock; KALV is a small-cap quality compounder stock. COSM pays a dividend while PHVS, HROW, KALV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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