Drug Manufacturers - Specialty & Generic
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5 / 10Stock Comparison
EBS vs BRKR vs WAT vs SIGA vs A
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Devices
Medical - Diagnostics & Research
Drug Manufacturers - Specialty & Generic
Medical - Diagnostics & Research
EBS vs BRKR vs WAT vs SIGA vs A — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Medical - Devices | Medical - Diagnostics & Research | Drug Manufacturers - Specialty & Generic | Medical - Diagnostics & Research |
| Market Cap | $472M | $6.66B | $22.83B | $339M | $33.58B |
| Revenue (TTM) | $743M | $3.46B | $3.77B | $94M | $7.07B |
| Net Income (TTM) | $53M | $-12M | $449M | $-4.04T | $1.29B |
| Gross Margin | 47.1% | 45.3% | 55.0% | 61.8% | 38.8% |
| Operating Margin | 14.7% | 4.9% | 17.1% | 27.7% | 20.6% |
| Forward P/E | 17.6x | 20.7x | 24.4x | 2.8x | 19.9x |
| Total Debt | $572M | $2.04B | $1.41B | $595K | $3.35B |
| Cash & Equiv. | $205M | $299M | $588M | $155M | $1.79B |
EBS vs BRKR vs WAT vs SIGA vs A — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Emergent BioSolutio… (EBS) | 100 | 10.9 | -89.1% |
| Bruker Corporation (BRKR) | 100 | 101.0 | +1.0% |
| Waters Corporation (WAT) | 100 | 175.3 | +75.3% |
| SIGA Technologies, … (SIGA) | 100 | 79.0 | -21.0% |
| Agilent Technologie… (A) | 100 | 134.6 | +34.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: EBS vs BRKR vs WAT vs SIGA vs A
Each card shows where this stock fits in a portfolio — not just who wins on paper.
EBS is the clearest fit if your priority is momentum.
- +92.7% vs WAT's +1.4%
Among these 5 stocks, BRKR doesn't own a clear edge in any measured category.
WAT has the current edge in this matchup, primarily because of its strength in growth exposure.
- Rev growth 7.0%, EPS growth 0.5%, 3Y rev CAGR 2.1%
- 7.0% revenue growth vs SIGA's -31.8%
- Beta 1.07 vs EBS's 1.83, lower leverage
SIGA is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- Dividend streak 4 yrs, beta 1.15, yield 12.7%
- 7.6% 10Y total return vs WAT's 162.0%
- Lower volatility, beta 1.15, Low D/E 0.3%, current ratio 11.83x
- Beta 1.15, yield 12.7%, current ratio 11.83x
A ranks third and is worth considering specifically for valuation efficiency.
- PEG 1.35 vs WAT's 4.70
- 18.3% margin vs SIGA's -43K%
- 10.1% ROA vs SIGA's -7.4%, ROIC 13.5% vs 33.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 7.0% revenue growth vs SIGA's -31.8% | |
| Value | Lower P/E (2.8x vs 24.4x) | |
| Quality / Margins | 18.3% margin vs SIGA's -43K% | |
| Stability / Safety | Beta 1.07 vs EBS's 1.83, lower leverage | |
| Dividends | 12.7% yield, 4-year raise streak, vs A's 0.8%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +92.7% vs WAT's +1.4% | |
| Efficiency (ROA) | 10.1% ROA vs SIGA's -7.4%, ROIC 13.5% vs 33.7% |
EBS vs BRKR vs WAT vs SIGA vs A — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
EBS vs BRKR vs WAT vs SIGA vs A — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
SIGA leads in 3 of 6 categories
EBS leads 1 • WAT leads 1 • BRKR leads 0 • A leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
SIGA leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
A is the larger business by revenue, generating $7.1B annually — 75.3x SIGA's $94M. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to SIGA's -43117.4%. On growth, WAT holds the edge at +91.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $743M | $3.5B | $3.8B | $94M | $7.1B |
| EBITDAEarnings before interest/tax | $207M | $397M | $953M | $26M | $1.7B |
| Net IncomeAfter-tax profit | $53M | -$12M | $449M | -$4.04T | $1.3B |
| Free Cash FlowCash after capex | $157M | $51M | $264M | $33M | $993M |
| Gross MarginGross profit ÷ Revenue | +47.1% | +45.3% | +55.0% | +61.8% | +38.8% |
| Operating MarginEBIT ÷ Revenue | +14.7% | +4.9% | +17.1% | +27.7% | +20.6% |
| Net MarginNet income ÷ Revenue | +7.1% | -0.3% | +11.9% | -43117.4% | +18.3% |
| FCF MarginFCF ÷ Revenue | +21.1% | +1.5% | +7.0% | +35.2% | +14.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | -23.6% | +2.7% | +91.5% | -11.3% | +7.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -76.3% | -79.2% | -142.9% | — | -3.6% |
Valuation Metrics
EBS leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 9.8x trailing earnings, EBS trades at a 70% valuation discount to WAT's 32.6x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.76x vs WAT's 6.29x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $472M | $6.7B | $22.8B | $339M | $33.6B |
| Enterprise ValueMkt cap + debt − cash | $838M | $8.4B | $23.7B | $185M | $35.1B |
| Trailing P/EPrice ÷ TTM EPS | 9.82x | -291.53x | 32.55x | 14.33x | 25.96x |
| Forward P/EPrice ÷ next-FY EPS est. | 17.57x | 20.68x | 24.36x | 2.78x | 19.87x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 6.29x | — | 1.76x |
| EV / EBITDAEnterprise value multiple | 4.02x | 18.41x | 21.51x | 7.60x | 19.89x |
| Price / SalesMarket cap ÷ Revenue | 0.64x | 1.94x | 7.21x | 3.58x | 4.83x |
| Price / BookPrice ÷ Book value/share | 0.99x | 2.64x | 8.17x | 1.70x | 5.00x |
| Price / FCFMarket cap ÷ FCF | 3.01x | 153.73x | 42.30x | 6.96x | 29.15x |
Profitability & Efficiency
SIGA leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $-11 for SIGA. SIGA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to EBS's 1.09x. On the Piotroski fundamental quality scale (0–9), EBS scores 7/9 vs WAT's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +9.6% | -0.5% | +8.0% | -10.7% | +18.7% |
| ROA (TTM)Return on assets | +3.7% | -0.2% | +4.6% | -7.4% | +10.1% |
| ROICReturn on invested capital | +8.5% | +4.4% | +20.3% | +33.7% | +13.5% |
| ROCEReturn on capital employed | +9.1% | +5.0% | +18.5% | +11.3% | +14.5% |
| Piotroski ScoreFundamental quality 0–9 | 7 | 4 | 4 | 5 | 5 |
| Debt / EquityFinancial leverage | 1.09x | 0.81x | 0.55x | 0.00x | 0.50x |
| Net DebtTotal debt minus cash | $367M | $1.7B | $820M | -$154M | $1.6B |
| Cash & Equiv.Liquid assets | $205M | $299M | $588M | $155M | $1.8B |
| Total DebtShort + long-term debt | $572M | $2.0B | $1.4B | $595,169 | $3.4B |
| Interest CoverageEBIT ÷ Interest expense | 1.84x | 1.14x | 6.72x | — | 19.53x |
Total Returns (Dividends Reinvested)
SIGA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in WAT five years ago would be worth $11,133 today (with dividends reinvested), compared to $1,482 for EBS. Over the past 12 months, EBS leads with a +92.7% total return vs WAT's +1.4%. The 3-year compound annual growth rate (CAGR) favors SIGA at 6.9% vs BRKR's -16.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -27.0% | -9.0% | -8.3% | -15.0% | -13.6% |
| 1-Year ReturnPast 12 months | +92.7% | +7.8% | +1.4% | +1.5% | +11.3% |
| 3-Year ReturnCumulative with dividends | +0.2% | -42.5% | +18.1% | +22.2% | -8.2% |
| 5-Year ReturnCumulative with dividends | -85.2% | -35.5% | +11.3% | +1.4% | -8.0% |
| 10-Year ReturnCumulative with dividends | -76.6% | +67.1% | +162.0% | +764.0% | +205.7% |
| CAGR (3Y)Annualised 3-year return | +0.1% | -16.9% | +5.7% | +6.9% | -2.8% |
Risk & Volatility
WAT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
WAT is the less volatile stock with a 1.07 beta — it tends to amplify market swings less than EBS's 1.83 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. WAT currently trades 84.6% from its 52-week high vs SIGA's 49.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.83x | 1.59x | 1.07x | 1.15x | 1.23x |
| 52-Week HighHighest price in past year | $14.06 | $56.22 | $414.15 | $9.62 | $160.27 |
| 52-Week LowLowest price in past year | $4.72 | $28.53 | $275.05 | $4.29 | $104.79 |
| % of 52W HighCurrent price vs 52-week peak | +65.0% | +77.8% | +84.6% | +49.2% | +74.0% |
| RSI (14)Momentum oscillator 0–100 | 61.4 | 64.8 | 64.9 | 47.0 | 52.5 |
| Avg Volume (50D)Average daily shares traded | 873K | 1.9M | 999K | 688K | 2.0M |
Analyst Outlook
Evenly matched — SIGA and A each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: EBS as "Buy", BRKR as "Buy", WAT as "Hold", SIGA as "Buy", A as "Buy". Consensus price targets imply 39.9% upside for A (target: $166) vs 14.9% for WAT (target: $403). For income investors, SIGA offers the higher dividend yield at 12.73% vs BRKR's 0.34%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $12.00 | $52.13 | $402.57 | — | $166.00 |
| # AnalystsCovering analysts | 15 | 32 | 34 | 1 | 38 |
| Dividend YieldAnnual dividend ÷ price | — | +0.3% | — | +12.7% | +0.8% |
| Dividend StreakConsecutive years of raises | 1 | 0 | 1 | 4 | 10 |
| Dividend / ShareAnnual DPS | — | $0.15 | — | $0.60 | $0.99 |
| Buyback YieldShare repurchases ÷ mkt cap | +5.3% | +0.2% | +0.1% | 0.0% | +1.3% |
SIGA leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). EBS leads in 1 (Valuation Metrics). 1 tied.
EBS vs BRKR vs WAT vs SIGA vs A: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is EBS or BRKR or WAT or SIGA or A a better buy right now?
For growth investors, Waters Corporation (WAT) is the stronger pick with 7.
0% revenue growth year-over-year, versus -31. 8% for SIGA Technologies, Inc. (SIGA). Emergent BioSolutions Inc. (EBS) offers the better valuation at 9. 8x trailing P/E (17. 6x forward), making it the more compelling value choice. Analysts rate Emergent BioSolutions Inc. (EBS) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — EBS or BRKR or WAT or SIGA or A?
On trailing P/E, Emergent BioSolutions Inc.
(EBS) is the cheapest at 9. 8x versus Waters Corporation at 32. 6x. On forward P/E, SIGA Technologies, Inc. is actually cheaper at 2. 8x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 35x versus Waters Corporation's 4. 70x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — EBS or BRKR or WAT or SIGA or A?
Over the past 5 years, Waters Corporation (WAT) delivered a total return of +11.
3%, compared to -85. 2% for Emergent BioSolutions Inc. (EBS). Over 10 years, the gap is even starker: SIGA returned +764. 0% versus EBS's -76. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — EBS or BRKR or WAT or SIGA or A?
By beta (market sensitivity over 5 years), Waters Corporation (WAT) is the lower-risk stock at 1.
07β versus Emergent BioSolutions Inc. 's 1. 83β — meaning EBS is approximately 71% more volatile than WAT relative to the S&P 500. On balance sheet safety, SIGA Technologies, Inc. (SIGA) carries a lower debt/equity ratio of 0% versus 109% for Emergent BioSolutions Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — EBS or BRKR or WAT or SIGA or A?
By revenue growth (latest reported year), Waters Corporation (WAT) is pulling ahead at 7.
0% versus -31. 8% for SIGA Technologies, Inc. (SIGA). On earnings-per-share growth, the picture is similar: Emergent BioSolutions Inc. grew EPS 125. 8% year-over-year, compared to -119. 7% for Bruker Corporation. Over a 3-year CAGR, BRKR leads at 10. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — EBS or BRKR or WAT or SIGA or A?
SIGA Technologies, Inc.
(SIGA) is the more profitable company, earning 24. 6% net margin versus -0. 3% for Bruker Corporation — meaning it keeps 24. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: WAT leads at 28. 2% versus 6. 9% for BRKR. At the gross margin level — before operating expenses — SIGA leads at 68. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is EBS or BRKR or WAT or SIGA or A more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 35x versus Waters Corporation's 4. 70x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, SIGA Technologies, Inc. (SIGA) trades at 2. 8x forward P/E versus 24. 4x for Waters Corporation — 21. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for A: 39. 9% to $166. 00.
08Which pays a better dividend — EBS or BRKR or WAT or SIGA or A?
In this comparison, SIGA (12.
7% yield), A (0. 8% yield), BRKR (0. 3% yield) pay a dividend. EBS, WAT do not pay a meaningful dividend and should not be held primarily for income.
09Is EBS or BRKR or WAT or SIGA or A better for a retirement portfolio?
For long-horizon retirement investors, SIGA Technologies, Inc.
(SIGA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), 12. 7% yield, +764. 0% 10Y return). Emergent BioSolutions Inc. (EBS) carries a higher beta of 1. 83 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SIGA: +764. 0%, EBS: -76. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between EBS and BRKR and WAT and SIGA and A?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: EBS is a small-cap deep-value stock; BRKR is a small-cap quality compounder stock; WAT is a mid-cap quality compounder stock; SIGA is a small-cap deep-value stock; A is a mid-cap quality compounder stock. SIGA, A pay a dividend while EBS, BRKR, WAT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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