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Stock Comparison

EDSA vs MRK vs KO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
EDSA
Edesa Biotech, Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$50M
5Y Perf.-83.6%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$298.30B
5Y Perf.+61.0%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.22B
5Y Perf.+84.7%

EDSA vs MRK vs KO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
EDSA logoEDSA
MRK logoMRK
KO logoKO
IndustryBiotechnologyDrug Manufacturers - GeneralBeverages - Non-Alcoholic
Market Cap$50M$298.30B$355.22B
Revenue (TTM)$0.00$64.93B$49.28B
Net Income (TTM)$-10M$18.25B$13.70B
Gross Margin74.2%61.7%
Operating Margin41.1%29.3%
Forward P/E23.5x25.2x
Total Debt$0.00$50.53B$45.49B
Cash & Equiv.$11M$14.56B$10.27B

EDSA vs MRK vs KOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

EDSA
MRK
KO
StockJun 20Jun 26Return
Edesa Biotech, Inc. (EDSA)10016.4-83.6%
Merck & Co., Inc. (MRK)100161.0+61.0%
The Coca-Cola Compa… (KO)100184.7+84.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: EDSA vs MRK vs KO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: MRK leads in 5 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Edesa Biotech, Inc. is the stronger pick specifically for recent price momentum and sentiment. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇MRK emerged as the overall leader. Track its performance:
EDSA
Edesa Biotech, Inc.
The Momentum Pick

EDSA is the clearest fit if your priority is momentum.

  • +203.8% vs KO's +17.4%
Best for: momentum
MRK
Merck & Co., Inc.
The Income Pick

MRK carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 15 yrs, beta 0.34, yield 2.7%
  • 172.8% 10Y total return vs KO's 120.9%
  • Lower volatility, beta 0.34, Low D/E 96.0%, current ratio 1.54x
Best for: income & stability and long-term compounding
KO
The Coca-Cola Company
The Growth Play

KO is the clearest fit if your priority is growth exposure.

  • Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
  • 1.9% revenue growth vs EDSA's -82.2%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthKO logoKO1.9% revenue growth vs EDSA's -82.2%
ValueMRK logoMRKLower P/E (23.5x vs 25.2x), PEG 1.11 vs 2.26
Quality / MarginsMRK logoMRK28.1% margin vs EDSA's 0.0%
Stability / SafetyMRK logoMRKLower D/E ratio (96.0% vs 132.7%)
DividendsMRK logoMRK2.7% yield, 15-year raise streak, vs KO's 2.5%, (1 stock pays no dividend)
Momentum (1Y)EDSA logoEDSA+203.8% vs KO's +17.4%
Efficiency (ROA)MRK logoMRK14.6% ROA vs EDSA's -75.2%, ROIC 22.0% vs -452.3%

EDSA vs MRK vs KO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
EDSAEdesa Biotech, Inc.
FY 2018
Product
100.0%$211,849
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B

EDSA vs MRK vs KO — Financial Metrics

Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLMRKLAGGINGKO

Income & Cash Flow (Last 12 Months)

Evenly matched — MRK and KO each lead in 3 of 6 comparable metrics.

MRK and EDSA operate at a comparable scale, with $64.9B and $0 in trailing revenue. Profitability is closely matched — net margins range from 28.1% (MRK) to 27.8% (KO). On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricEDSA logoEDSAEdesa Biotech, In…MRK logoMRKMerck & Co., Inc.KO logoKOThe Coca-Cola Com…
RevenueTrailing 12 months$0$64.9B$49.3B
EBITDAEarnings before interest/tax-$11M$32.4B$15.5B
Net IncomeAfter-tax profit-$10M$18.3B$13.7B
Free Cash FlowCash after capex-$8M$12.4B$12.6B
Gross MarginGross profit ÷ Revenue+74.2%+61.7%
Operating MarginEBIT ÷ Revenue+41.1%+29.3%
Net MarginNet income ÷ Revenue+28.1%+27.8%
FCF MarginFCF ÷ Revenue+19.0%+25.5%
Rev. Growth (YoY)Latest quarter vs prior year+4.5%+12.1%
EPS Growth (YoY)Latest quarter vs prior year-66.7%-19.6%+18.2%
Evenly matched — MRK and KO each lead in 3 of 6 comparable metrics.

Valuation Metrics

MRK leads this category, winning 5 of 7 comparable metrics.

At 16.6x trailing earnings, MRK trades at a 39% valuation discount to KO's 27.1x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.78x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricEDSA logoEDSAEdesa Biotech, In…MRK logoMRKMerck & Co., Inc.KO logoKOThe Coca-Cola Com…
Market CapShares × price$50M$298.3B$355.2B
Enterprise ValueMkt cap + debt − cash$39M$334.3B$390.4B
Trailing P/EPrice ÷ TTM EPS-4.45x16.59x27.15x
Forward P/EPrice ÷ next-FY EPS est.23.50x25.24x
PEG RatioP/E ÷ EPS growth rate0.78x2.43x
EV / EBITDAEnterprise value multiple11.40x26.36x
Price / SalesMarket cap ÷ Revenue4.59x7.41x
Price / BookPrice ÷ Book value/share2.58x5.75x10.39x
Price / FCFMarket cap ÷ FCF24.13x67.07x
MRK leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

MRK leads this category, winning 5 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-82 for EDSA. MRK carries lower financial leverage with a 0.96x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs EDSA's 2/9, reflecting strong financial health.

MetricEDSA logoEDSAEdesa Biotech, In…MRK logoMRKMerck & Co., Inc.KO logoKOThe Coca-Cola Com…
ROE (TTM)Return on equity-82.3%+36.1%+41.1%
ROA (TTM)Return on assets-75.2%+14.6%+13.1%
ROICReturn on invested capital-4.5%+22.0%+15.8%
ROCEReturn on capital employed-109.6%+23.8%+17.3%
Piotroski ScoreFundamental quality 0–9247
Debt / EquityFinancial leverage0.96x1.33x
Net DebtTotal debt minus cash-$11M$36.0B$35.2B
Cash & Equiv.Liquid assets$11M$14.6B$10.3B
Total DebtShort + long-term debt$0$50.5B$45.5B
Interest CoverageEBIT ÷ Interest expense19.68x10.70x
MRK leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — EDSA and MRK and KO each lead in 2 of 6 comparable metrics.

A $10,000 investment in MRK five years ago would be worth $17,802 today (with dividends reinvested), compared to $1,382 for EDSA. Over the past 12 months, EDSA leads with a +203.8% total return vs KO's +17.4%. The 3-year compound annual growth rate (CAGR) favors KO at 13.7% vs EDSA's -1.3% — a key indicator of consistent wealth creation.

MetricEDSA logoEDSAEdesa Biotech, In…MRK logoMRKMerck & Co., Inc.KO logoKOThe Coca-Cola Com…
YTD ReturnYear-to-date+276.7%+14.3%+20.2%
1-Year ReturnPast 12 months+203.8%+54.5%+17.4%
3-Year ReturnCumulative with dividends-3.9%+18.6%+46.9%
5-Year ReturnCumulative with dividends-86.2%+78.0%+63.6%
10-Year ReturnCumulative with dividends-99.3%+172.8%+120.9%
CAGR (3Y)Annualised 3-year return-1.3%+5.8%+13.7%
Evenly matched — EDSA and MRK and KO each lead in 2 of 6 comparable metrics.

Risk & Volatility

Evenly matched — EDSA and KO each lead in 1 of 2 comparable metrics.

EDSA is the less volatile stock with a -0.29 beta — it tends to amplify market swings less than MRK's 0.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.2% from its 52-week high vs EDSA's 27.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricEDSA logoEDSAEdesa Biotech, In…MRK logoMRKMerck & Co., Inc.KO logoKOThe Coca-Cola Com…
Beta (5Y)Sensitivity to S&P 500-0.29x0.34x-0.15x
52-Week HighHighest price in past year$20.32$125.14$84.04
52-Week LowLowest price in past year$0.72$76.66$65.35
% of 52W HighCurrent price vs 52-week peak+27.8%+96.5%+98.2%
RSI (14)Momentum oscillator 0–10034.355.465.7
Avg Volume (50D)Average daily shares traded617K7.1M12.6M
Evenly matched — EDSA and KO each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — MRK and KO each lead in 1 of 2 comparable metrics.

Analyst consensus: EDSA as "Buy", MRK as "Buy", KO as "Buy". Consensus price targets imply 8.2% upside for MRK (target: $131) vs 4.6% for KO (target: $86). For income investors, MRK offers the higher dividend yield at 2.70% vs KO's 2.47%.

MetricEDSA logoEDSAEdesa Biotech, In…MRK logoMRKMerck & Co., Inc.KO logoKOThe Coca-Cola Com…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$130.69$86.29
# AnalystsCovering analysts23748
Dividend YieldAnnual dividend ÷ price+2.7%+2.5%
Dividend StreakConsecutive years of raises1556
Dividend / ShareAnnual DPS$3.26$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.7%+0.2%
Evenly matched — MRK and KO each lead in 1 of 2 comparable metrics.
Key Takeaway

MRK leads in 2 of 6 categories — strongest in Valuation Metrics and Profitability & Efficiency. 4 categories are tied.

Best OverallMerck & Co., Inc. (MRK)Leads 2 of 6 categories
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EDSA vs MRK vs KO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is EDSA or MRK or KO a better buy right now?

For growth investors, The Coca-Cola Company (KO) is the stronger pick with 1.

9% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Merck & Co. , Inc. (MRK) offers the better valuation at 16. 6x trailing P/E (23. 5x forward), making it the more compelling value choice. Analysts rate Edesa Biotech, Inc. (EDSA) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — EDSA or MRK or KO?

On trailing P/E, Merck & Co.

, Inc. (MRK) is the cheapest at 16. 6x versus The Coca-Cola Company at 27. 1x. On forward P/E, Merck & Co. , Inc. is actually cheaper at 23. 5x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co. , Inc. wins at 1. 11x versus The Coca-Cola Company's 2. 26x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — EDSA or MRK or KO?

Over the past 5 years, Merck & Co.

, Inc. (MRK) delivered a total return of +78. 0%, compared to -86. 2% for Edesa Biotech, Inc. (EDSA). Over 10 years, the gap is even starker: MRK returned +172. 8% versus EDSA's -99. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — EDSA or MRK or KO?

By beta (market sensitivity over 5 years), Edesa Biotech, Inc.

(EDSA) is the lower-risk stock at -0. 29β versus Merck & Co. , Inc. 's 0. 34β — meaning MRK is approximately -219% more volatile than EDSA relative to the S&P 500. On balance sheet safety, Merck & Co. , Inc. (MRK) carries a lower debt/equity ratio of 96% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.

05

Which is growing faster — EDSA or MRK or KO?

By revenue growth (latest reported year), The Coca-Cola Company (KO) is pulling ahead at 1.

9% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: Edesa Biotech, Inc. grew EPS 34. 2% year-over-year, compared to 8. 0% for Merck & Co. , Inc.. Over a 3-year CAGR, KO leads at 3. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — EDSA or MRK or KO?

Merck & Co.

, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus 0. 0% for Edesa Biotech, Inc. — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus 0. 0% for EDSA. At the gross margin level — before operating expenses — MRK leads at 72. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is EDSA or MRK or KO more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Merck & Co. , Inc. (MRK) is the more undervalued stock at a PEG of 1. 11x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Merck & Co. , Inc. (MRK) trades at 23. 5x forward P/E versus 25. 2x for The Coca-Cola Company — 1. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MRK: 8. 2% to $130. 69.

08

Which pays a better dividend — EDSA or MRK or KO?

In this comparison, MRK (2.

7% yield), KO (2. 5% yield) pay a dividend. EDSA does not pay a meaningful dividend and should not be held primarily for income.

09

Is EDSA or MRK or KO better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

15), 2. 5% yield, +120. 9% 10Y return). Both have compounded well over 10 years (KO: +120. 9%, EDSA: -99. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between EDSA and MRK and KO?

These companies operate in different sectors (EDSA (Healthcare) and MRK (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: EDSA is a small-cap quality compounder stock; MRK is a large-cap deep-value stock; KO is a large-cap quality compounder stock. MRK, KO pay a dividend while EDSA does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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