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EDSA logo
EDSA
NUVB logo
NUVB
KO logo
KO
PRAX logo
PRAX
IMVT logo
IMVT
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Stock Comparison

EDSA vs NUVB vs KO vs PRAX vs IMVT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
EDSA
Edesa Biotech, Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$52M
5Y Perf.-86.3%
NUVB
Nuvation Bio Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$1.71B
5Y Perf.-51.2%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+71.9%
PRAX
Praxis Precision Medicines, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.70B
5Y Perf.-49.2%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.-22.9%

EDSA vs NUVB vs KO vs PRAX vs IMVT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
EDSA logoEDSA
NUVB logoNUVB
KO logoKO
PRAX logoPRAX
IMVT logoIMVT
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicBiotechnologyBiotechnology
Market Cap$52M$1.71B$355.61B$7.70B$6.90B
Revenue (TTM)$0.00$143M$49.28B$0.00$0.00
Net Income (TTM)$-10M$-146M$13.70B$-327M$-506M
Gross Margin91.6%61.7%
Operating Margin-105.0%29.3%
Forward P/E25.3x
Total Debt$0.00$10M$45.49B$110K$72K
Cash & Equiv.$11M$164M$10.27B$357M$902M

EDSA vs NUVB vs KO vs PRAX vs IMVTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

EDSA
NUVB
KO
PRAX
IMVT
StockOct 20Jun 26Return
Edesa Biotech, Inc. (EDSA)10013.7-86.3%
Nuvation Bio Inc. (NUVB)10048.8-51.2%
The Coca-Cola Compa… (KO)100171.9+71.9%
Praxis Precision Me… (PRAX)10050.8-49.2%
Immunovant, Inc. (IMVT)10077.1-22.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: EDSA vs NUVB vs KO vs PRAX vs IMVT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO leads in 3 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Praxis Precision Medicines, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. NUVB also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇KO emerged as the overall leader. Track its performance:
EDSA
Edesa Biotech, Inc.
The Lower-Volatility Pick

EDSA lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
NUVB
Nuvation Bio Inc.
The Growth Play

NUVB ranks third and is worth considering specifically for growth exposure.

  • Rev growth 7.0%, EPS growth 71.6%
  • 7.0% revenue growth vs PRAX's -100.0%
Best for: growth exposure
KO
The Coca-Cola Company
The Quality Compounder

KO carries the broadest edge in this set and is the clearest fit for quality and dividends.

  • 27.8% margin vs NUVB's -102.1%
  • 2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
  • 13.1% ROA vs EDSA's -75.2%, ROIC 15.8% vs -452.3%
Best for: quality and dividends
PRAX
Praxis Precision Medicines, Inc.
The Income Pick

PRAX is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 1.55
  • Lower volatility, beta 1.55, Low D/E 0.0%, current ratio 10.22x
  • Beta 1.55, current ratio 10.22x
  • Beta 1.55 vs NUVB's 2.23, lower leverage
Best for: income & stability and sleep-well-at-night
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding.

  • 237.9% 10Y total return vs KO's 121.1%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthNUVB logoNUVB7.0% revenue growth vs PRAX's -100.0%
Quality / MarginsKO logoKO27.8% margin vs NUVB's -102.1%
Stability / SafetyPRAX logoPRAXBeta 1.55 vs NUVB's 2.23, lower leverage
DividendsKO logoKO2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)PRAX logoPRAX+491.9% vs KO's +17.2%
Efficiency (ROA)KO logoKO13.1% ROA vs EDSA's -75.2%, ROIC 15.8% vs -452.3%

EDSA vs NUVB vs KO vs PRAX vs IMVT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

EDSAEdesa Biotech, Inc.
FY 2018
Product
100.0%$211,849
NUVBNuvation Bio Inc.
FY 2025
License
60.8%$38M
Product
39.2%$25M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
PRAXPraxis Precision Medicines, Inc.
FY 2024
License
76.8%$9M
Upfront Payment
23.2%$3M
IMVTImmunovant, Inc.

Segment breakdown not available.

EDSA vs NUVB vs KO vs PRAX vs IMVT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKOLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

Evenly matched — NUVB and KO each lead in 3 of 6 comparable metrics.

KO and IMVT operate at a comparable scale, with $49.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to NUVB's -102.1%. On growth, NUVB holds the edge at +26.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricEDSA logoEDSAEdesa Biotech, In…NUVB logoNUVBNuvation Bio Inc.KO logoKOThe Coca-Cola Com…PRAX logoPRAXPraxis Precision …IMVT logoIMVTImmunovant, Inc.
RevenueTrailing 12 months$0$143M$49.3B$0$0
EBITDAEarnings before interest/tax-$11M-$145M$15.5B-$357M-$532M
Net IncomeAfter-tax profit-$10M-$146M$13.7B-$327M-$506M
Free Cash FlowCash after capex-$8M-$126M$12.6B-$283M-$407M
Gross MarginGross profit ÷ Revenue+91.6%+61.7%
Operating MarginEBIT ÷ Revenue-105.0%+29.3%
Net MarginNet income ÷ Revenue-102.1%+27.8%
FCF MarginFCF ÷ Revenue-88.1%+25.5%
Rev. Growth (YoY)Latest quarter vs prior year+26.0%+12.1%
EPS Growth (YoY)Latest quarter vs prior year-66.7%+106.3%+18.2%+2.7%-14.1%
Evenly matched — NUVB and KO each lead in 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — EDSA and KO and PRAX each lead in 1 of 3 comparable metrics.
MetricEDSA logoEDSAEdesa Biotech, In…NUVB logoNUVBNuvation Bio Inc.KO logoKOThe Coca-Cola Com…PRAX logoPRAXPraxis Precision …IMVT logoIMVTImmunovant, Inc.
Market CapShares × price$52M$1.7B$355.6B$7.7B$6.9B
Enterprise ValueMkt cap + debt − cash$41M$1.6B$390.8B$7.3B$6.0B
Trailing P/EPrice ÷ TTM EPS-4.57x-8.20x27.18x-19.77x-12.14x
Forward P/EPrice ÷ next-FY EPS est.25.27x
PEG RatioP/E ÷ EPS growth rate2.43x
EV / EBITDAEnterprise value multiple26.39x
Price / SalesMarket cap ÷ Revenue27.16x7.42x
Price / BookPrice ÷ Book value/share2.64x5.50x10.40x6.83x7.19x
Price / FCFMarket cap ÷ FCF67.15x
Evenly matched — EDSA and KO and PRAX each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

KO leads this category, winning 6 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-82 for EDSA. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs IMVT's 2/9, reflecting strong financial health.

MetricEDSA logoEDSAEdesa Biotech, In…NUVB logoNUVBNuvation Bio Inc.KO logoKOThe Coca-Cola Com…PRAX logoPRAXPraxis Precision …IMVT logoIMVTImmunovant, Inc.
ROE (TTM)Return on equity-82.3%-44.1%+41.1%-43.0%-68.2%
ROA (TTM)Return on assets-75.2%-23.8%+13.1%-40.2%-62.2%
ROICReturn on invested capital-4.5%-54.3%+15.8%-65.0%
ROCEReturn on capital employed-109.6%-42.8%+17.3%-49.3%-68.3%
Piotroski ScoreFundamental quality 0–924732
Debt / EquityFinancial leverage0.03x1.33x0.00x0.00x
Net DebtTotal debt minus cash-$11M-$154M$35.2B-$357M-$902M
Cash & Equiv.Liquid assets$11M$164M$10.3B$357M$902M
Total DebtShort + long-term debt$0$10M$45.5B$110,000$72,000
Interest CoverageEBIT ÷ Interest expense-162.11x10.70x
KO leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

PRAX leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $1,441 for EDSA. Over the past 12 months, PRAX leads with a +491.9% total return vs KO's +17.2%. The 3-year compound annual growth rate (CAGR) favors PRAX at 164.8% vs EDSA's -0.5% — a key indicator of consistent wealth creation.

MetricEDSA logoEDSAEdesa Biotech, In…NUVB logoNUVBNuvation Bio Inc.KO logoKOThe Coca-Cola Com…PRAX logoPRAXPraxis Precision …IMVT logoIMVTImmunovant, Inc.
YTD ReturnYear-to-date+286.7%-42.7%+20.3%-6.9%+29.8%
1-Year ReturnPast 12 months+195.9%+171.8%+17.2%+491.9%+110.9%
3-Year ReturnCumulative with dividends-1.4%+182.8%+47.0%+1757.4%+55.0%
5-Year ReturnCumulative with dividends-85.6%-56.9%+65.6%-14.2%+213.0%
10-Year ReturnCumulative with dividends-99.3%-50.8%+121.1%-36.1%+237.9%
CAGR (3Y)Annualised 3-year return-0.5%+41.4%+13.7%+164.8%+15.7%
PRAX leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than NUVB's 2.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs EDSA's 28.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricEDSA logoEDSAEdesa Biotech, In…NUVB logoNUVBNuvation Bio Inc.KO logoKOThe Coca-Cola Com…PRAX logoPRAXPraxis Precision …IMVT logoIMVTImmunovant, Inc.
Beta (5Y)Sensitivity to S&P 500-0.18x2.23x-0.20x1.55x1.66x
52-Week HighHighest price in past year$20.32$9.75$84.04$366.52$36.27
52-Week LowLowest price in past year$0.72$1.57$65.35$37.19$14.32
% of 52W HighCurrent price vs 52-week peak+28.5%+50.5%+98.3%+72.7%+92.7%
RSI (14)Momentum oscillator 0–10036.850.260.631.957.9
Avg Volume (50D)Average daily shares traded612K4.0M12.7M396K1.9M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: EDSA as "Buy", NUVB as "Buy", KO as "Buy", PRAX as "Buy", IMVT as "Buy". Consensus price targets imply 164.2% upside for NUVB (target: $13) vs 4.2% for KO (target: $86). KO is the only dividend payer here at 2.46% yield — a key consideration for income-focused portfolios.

MetricEDSA logoEDSAEdesa Biotech, In…NUVB logoNUVBNuvation Bio Inc.KO logoKOThe Coca-Cola Com…PRAX logoPRAXPraxis Precision …IMVT logoIMVTImmunovant, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$13.00$86.13$607.15$43.67
# AnalystsCovering analysts29481623
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises56
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.2%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

KO leads in 2 of 6 categories (Profitability & Efficiency, Risk & Volatility). PRAX leads in 1 (Total Returns). 2 tied.

Best OverallThe Coca-Cola Company (KO)Leads 2 of 6 categories
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EDSA vs NUVB vs KO vs PRAX vs IMVT: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is EDSA or NUVB or KO or PRAX or IMVT a better buy right now?

For growth investors, Nuvation Bio Inc.

(NUVB) is the stronger pick with 699. 0% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). The Coca-Cola Company (KO) offers the better valuation at 27. 2x trailing P/E (25. 3x forward), making it the more compelling value choice. Analysts rate Edesa Biotech, Inc. (EDSA) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — EDSA or NUVB or KO or PRAX or IMVT?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -85. 6% for Edesa Biotech, Inc. (EDSA). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus EDSA's -99. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — EDSA or NUVB or KO or PRAX or IMVT?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Nuvation Bio Inc. 's 2. 23β — meaning NUVB is approximately -1212% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.

04

Which is growing faster — EDSA or NUVB or KO or PRAX or IMVT?

By revenue growth (latest reported year), Nuvation Bio Inc.

(NUVB) is pulling ahead at 699. 0% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Nuvation Bio Inc. grew EPS 71. 6% year-over-year, compared to -32. 0% for Praxis Precision Medicines, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — EDSA or NUVB or KO or PRAX or IMVT?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -325. 3% for Nuvation Bio Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -338. 7% for NUVB. At the gross margin level — before operating expenses — NUVB leads at 86. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is EDSA or NUVB or KO or PRAX or IMVT more undervalued right now?

Analyst consensus price targets imply the most upside for NUVB: 164.

2% to $13. 00.

07

Which pays a better dividend — EDSA or NUVB or KO or PRAX or IMVT?

In this comparison, KO (2.

5% yield) pays a dividend. EDSA, NUVB, PRAX, IMVT do not pay a meaningful dividend and should not be held primarily for income.

08

Is EDSA or NUVB or KO or PRAX or IMVT better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Nuvation Bio Inc. (NUVB) carries a higher beta of 2. 23 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, NUVB: -50. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between EDSA and NUVB and KO and PRAX and IMVT?

These companies operate in different sectors (EDSA (Healthcare) and NUVB (Healthcare) and KO (Consumer Defensive) and PRAX (Healthcare) and IMVT (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: EDSA is a small-cap quality compounder stock; NUVB is a small-cap high-growth stock; KO is a large-cap quality compounder stock; PRAX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock. KO pays a dividend while EDSA, NUVB, PRAX, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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