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ENGN
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IMVT logo
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PEP
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Stock Comparison

ENGN vs TGTX vs KO vs IMVT vs PEP

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ENGN
enGene Holdings Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$83M
5Y Perf.-78.9%
TGTX
TG Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.58B
5Y Perf.+286.6%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+41.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.-14.1%
PEP
PepsiCo, Inc.

Beverages - Non-Alcoholic

Consumer DefensiveNASDAQ • US
Market Cap$197.17B
5Y Perf.-14.3%

ENGN vs TGTX vs KO vs IMVT vs PEP — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ENGN logoENGN
TGTX logoTGTX
KO logoKO
IMVT logoIMVT
PEP logoPEP
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicBiotechnologyBeverages - Non-Alcoholic
Market Cap$83M$7.58B$355.61B$6.90B$197.17B
Revenue (TTM)$700M$49.28B$0.00$93.92B
Net Income (TTM)$-122M$462M$13.70B$-506M$8.24B
Gross Margin83.0%61.7%54.1%
Operating Margin21.3%29.3%12.2%
Forward P/E35.9x25.3x16.7x
Total Debt$32M$261M$45.49B$72K$49.90B
Cash & Equiv.$50M$79M$10.27B$902M$9.16B

ENGN vs TGTX vs KO vs IMVT vs PEPLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ENGN
TGTX
KO
IMVT
PEP
StockNov 23Jun 26Return
enGene Holdings Inc. (ENGN)10021.1-78.9%
TG Therapeutics, In… (TGTX)100386.6+286.6%
The Coca-Cola Compa… (KO)100141.4+41.4%
Immunovant, Inc. (IMVT)10085.9-14.1%
PepsiCo, Inc. (PEP)10085.7-14.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: ENGN vs TGTX vs KO vs IMVT vs PEP

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TGTX leads in 4 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and profitability and margin quality. PepsiCo, Inc. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. IMVT also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇TGTX emerged as the overall leader. Track its performance:
ENGN
enGene Holdings Inc.
The Healthcare Pick

ENGN lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
TGTX
TG Therapeutics, Inc.
The Growth Play

TGTX carries the broadest edge in this set and is the clearest fit for growth exposure and defensive.

  • Rev growth 87.3%, EPS growth 17.5%, 3Y rev CAGR 5.0%
  • Beta 0.65, current ratio 4.10x
  • 87.3% revenue growth vs ENGN's -77.3%
  • 66.0% margin vs IMVT's 2.6%
Best for: growth exposure and defensive
KO
The Coca-Cola Company
The Value Pick

KO is the clearest fit if your priority is valuation efficiency.

  • PEG 2.26 vs PEP's 5.11
Best for: valuation efficiency
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.

  • 237.9% 10Y total return vs TGTX's 6.1%
  • Lower volatility, beta 1.66, Low D/E 0.0%, current ratio 9.09x
  • +110.9% vs ENGN's -50.2%
Best for: long-term compounding and sleep-well-at-night
PEP
PepsiCo, Inc.
The Income Pick

PEP is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 54 yrs, beta -0.11, yield 3.9%
  • Better valuation composite
  • 3.9% yield, 54-year raise streak, vs KO's 2.5%, (3 stocks pay no dividend)
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthTGTX logoTGTX87.3% revenue growth vs ENGN's -77.3%
ValuePEP logoPEPBetter valuation composite
Quality / MarginsTGTX logoTGTX66.0% margin vs IMVT's 2.6%
Stability / SafetyTGTX logoTGTXBeta 0.65 vs ENGN's 2.26
DividendsPEP logoPEP3.9% yield, 54-year raise streak, vs KO's 2.5%, (3 stocks pay no dividend)
Momentum (1Y)IMVT logoIMVT+110.9% vs ENGN's -50.2%
Efficiency (ROA)TGTX logoTGTX42.8% ROA vs IMVT's -62.2%

ENGN vs TGTX vs KO vs IMVT vs PEP — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ENGNenGene Holdings Inc.

Segment breakdown not available.

TGTXTG Therapeutics, Inc.
FY 2025
Product
98.5%$607M
Royalty
0.9%$6M
Other Revenue
0.6%$4M
License Revenue
0.0%$152,000
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
IMVTImmunovant, Inc.

Segment breakdown not available.

PEPPepsiCo, Inc.

Segment breakdown not available.

ENGN vs TGTX vs KO vs IMVT vs PEP — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLTGTXLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

TGTX leads this category, winning 4 of 6 comparable metrics.

PEP and IMVT operate at a comparable scale, with $93.9B and $0 in trailing revenue. TGTX is the more profitable business, keeping 66.0% of every revenue dollar as net income compared to PEP's 8.8%. On growth, TGTX holds the edge at +69.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricENGN logoENGNenGene Holdings I…TGTX logoTGTXTG Therapeutics, …KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.PEP logoPEPPepsiCo, Inc.
RevenueTrailing 12 months$700M$49.3B$0$93.9B
EBITDAEarnings before interest/tax-$127M$150M$15.5B-$532M$14.3B
Net IncomeAfter-tax profit-$122M$462M$13.7B-$506M$8.2B
Free Cash FlowCash after capex-$104M-$14M$12.6B-$407M$7.7B
Gross MarginGross profit ÷ Revenue+83.0%+61.7%+54.1%
Operating MarginEBIT ÷ Revenue+21.3%+29.3%+12.2%
Net MarginNet income ÷ Revenue+66.0%+27.8%+8.8%
FCF MarginFCF ÷ Revenue-2.0%+25.5%+8.2%
Rev. Growth (YoY)Latest quarter vs prior year+69.6%+12.1%+5.6%
EPS Growth (YoY)Latest quarter vs prior year+8.3%+2.9%+18.2%-14.1%+66.7%
TGTX leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

PEP leads this category, winning 4 of 7 comparable metrics.

At 17.9x trailing earnings, TGTX trades at a 34% valuation discount to KO's 27.2x P/E. Adjusting for growth (PEG ratio), KO offers better value at 2.43x vs PEP's 7.37x — a lower PEG means you pay less per unit of expected earnings growth.

MetricENGN logoENGNenGene Holdings I…TGTX logoTGTXTG Therapeutics, …KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.PEP logoPEPPepsiCo, Inc.
Market CapShares × price$83M$7.6B$355.6B$6.9B$197.2B
Enterprise ValueMkt cap + debt − cash$65M$7.8B$390.8B$6.0B$237.9B
Trailing P/EPrice ÷ TTM EPS-0.71x17.88x27.18x-12.14x24.05x
Forward P/EPrice ÷ next-FY EPS est.35.88x25.27x16.68x
PEG RatioP/E ÷ EPS growth rate2.43x7.37x
EV / EBITDAEnterprise value multiple62.82x26.39x16.63x
Price / SalesMarket cap ÷ Revenue12.30x7.42x2.10x
Price / BookPrice ÷ Book value/share0.49x12.33x10.40x7.19x9.63x
Price / FCFMarket cap ÷ FCF67.15x25.70x
PEP leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

TGTX leads this category, winning 4 of 9 comparable metrics.

TGTX delivers a 87.4% return on equity — every $100 of shareholder capital generates $87 in annual profit, vs $-68 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to PEP's 2.43x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ENGN's 1/9, reflecting strong financial health.

MetricENGN logoENGNenGene Holdings I…TGTX logoTGTXTG Therapeutics, …KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.PEP logoPEPPepsiCo, Inc.
ROE (TTM)Return on equity-55.8%+87.4%+41.1%-68.2%+40.1%
ROA (TTM)Return on assets-45.7%+42.8%+13.1%-62.2%+7.7%
ROICReturn on invested capital-67.4%+16.4%+15.8%+14.9%
ROCEReturn on capital employed-50.7%+17.7%+17.3%-68.3%+16.1%
Piotroski ScoreFundamental quality 0–914725
Debt / EquityFinancial leverage0.19x0.40x1.33x0.00x2.43x
Net DebtTotal debt minus cash-$18M$182M$35.2B-$902M$40.7B
Cash & Equiv.Liquid assets$50M$79M$10.3B$902M$9.2B
Total DebtShort + long-term debt$32M$261M$45.5B$72,000$49.9B
Interest CoverageEBIT ÷ Interest expense-40.18x5.67x10.70x10.34x
TGTX leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

TGTX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $810 for ENGN. Over the past 12 months, IMVT leads with a +110.9% total return vs ENGN's -50.2%. The 3-year compound annual growth rate (CAGR) favors TGTX at 23.6% vs ENGN's -56.7% — a key indicator of consistent wealth creation.

MetricENGN logoENGNenGene Holdings I…TGTX logoTGTXTG Therapeutics, …KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.PEP logoPEPPepsiCo, Inc.
YTD ReturnYear-to-date-81.7%+69.1%+20.3%+29.8%+3.5%
1-Year ReturnPast 12 months-50.2%+32.5%+17.2%+110.9%+13.4%
3-Year ReturnCumulative with dividends-91.9%+89.0%+47.0%+55.0%-11.7%
5-Year ReturnCumulative with dividends-91.9%+29.3%+65.6%+213.0%+14.3%
10-Year ReturnCumulative with dividends-91.9%+605.4%+121.1%+237.9%+82.3%
CAGR (3Y)Annualised 3-year return-56.7%+23.6%+13.7%+15.7%-4.1%
TGTX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ENGN's 2.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs ENGN's 13.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricENGN logoENGNenGene Holdings I…TGTX logoTGTXTG Therapeutics, …KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.PEP logoPEPPepsiCo, Inc.
Beta (5Y)Sensitivity to S&P 5002.26x0.65x-0.20x1.66x-0.11x
52-Week HighHighest price in past year$12.25$50.41$84.04$36.27$171.48
52-Week LowLowest price in past year$1.40$25.28$65.35$14.32$127.60
% of 52W HighCurrent price vs 52-week peak+13.2%+98.2%+98.3%+92.7%+84.1%
RSI (14)Momentum oscillator 0–10029.876.160.657.941.6
Avg Volume (50D)Average daily shares traded1.9M2.0M12.7M1.9M6.0M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — KO and PEP each lead in 1 of 2 comparable metrics.

Analyst consensus: ENGN as "Hold", TGTX as "Buy", KO as "Buy", IMVT as "Buy", PEP as "Hold". Consensus price targets imply 332.1% upside for ENGN (target: $7) vs 4.2% for KO (target: $86). For income investors, PEP offers the higher dividend yield at 3.86% vs KO's 2.46%.

MetricENGN logoENGNenGene Holdings I…TGTX logoTGTXTG Therapeutics, …KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.PEP logoPEPPepsiCo, Inc.
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuyHold
Price TargetConsensus 12-month target$7.00$54.50$86.13$43.67$167.88
# AnalystsCovering analysts913482345
Dividend YieldAnnual dividend ÷ price+2.5%+3.9%
Dividend StreakConsecutive years of raises005654
Dividend / ShareAnnual DPS$2.04$5.57
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.2%+0.2%0.0%+0.5%
Evenly matched — KO and PEP each lead in 1 of 2 comparable metrics.
Key Takeaway

TGTX leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PEP leads in 1 (Valuation Metrics). 1 tied.

Best OverallTG Therapeutics, Inc. (TGTX)Leads 3 of 6 categories
Loading custom metrics...

ENGN vs TGTX vs KO vs IMVT vs PEP: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ENGN or TGTX or KO or IMVT or PEP a better buy right now?

For growth investors, TG Therapeutics, Inc.

(TGTX) is the stronger pick with 87. 3% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). TG Therapeutics, Inc. (TGTX) offers the better valuation at 17. 9x trailing P/E (35. 9x forward), making it the more compelling value choice. Analysts rate TG Therapeutics, Inc. (TGTX) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ENGN or TGTX or KO or IMVT or PEP?

On trailing P/E, TG Therapeutics, Inc.

(TGTX) is the cheapest at 17. 9x versus The Coca-Cola Company at 27. 2x. On forward P/E, PepsiCo, Inc. is actually cheaper at 16. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: The Coca-Cola Company wins at 2. 26x versus PepsiCo, Inc. 's 5. 11x.

03

Which is the better long-term investment — ENGN or TGTX or KO or IMVT or PEP?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -91. 9% for enGene Holdings Inc. (ENGN). Over 10 years, the gap is even starker: TGTX returned +605. 4% versus ENGN's -91. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ENGN or TGTX or KO or IMVT or PEP?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus enGene Holdings Inc. 's 2. 26β — meaning ENGN is approximately -1227% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 2% for PepsiCo, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ENGN or TGTX or KO or IMVT or PEP?

By revenue growth (latest reported year), TG Therapeutics, Inc.

(TGTX) is pulling ahead at 87. 3% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: TG Therapeutics, Inc. grew EPS 1747% year-over-year, compared to -56. 8% for enGene Holdings Inc.. Over a 3-year CAGR, TGTX leads at 504. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ENGN or TGTX or KO or IMVT or PEP?

TG Therapeutics, Inc.

(TGTX) is the more profitable company, earning 72. 6% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 72. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — TGTX leads at 83. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ENGN or TGTX or KO or IMVT or PEP more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, The Coca-Cola Company (KO) is the more undervalued stock at a PEG of 2. 26x versus PepsiCo, Inc. 's 5. 11x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, PepsiCo, Inc. (PEP) trades at 16. 7x forward P/E versus 35. 9x for TG Therapeutics, Inc. — 19. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ENGN: 332. 1% to $7. 00.

08

Which pays a better dividend — ENGN or TGTX or KO or IMVT or PEP?

In this comparison, PEP (3.

9% yield), KO (2. 5% yield) pay a dividend. ENGN, TGTX, IMVT do not pay a meaningful dividend and should not be held primarily for income.

09

Is ENGN or TGTX or KO or IMVT or PEP better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). enGene Holdings Inc. (ENGN) carries a higher beta of 2. 26 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, ENGN: -91. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ENGN and TGTX and KO and IMVT and PEP?

These companies operate in different sectors (ENGN (Healthcare) and TGTX (Healthcare) and KO (Consumer Defensive) and IMVT (Healthcare) and PEP (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ENGN is a small-cap quality compounder stock; TGTX is a small-cap high-growth stock; KO is a large-cap quality compounder stock; IMVT is a small-cap quality compounder stock; PEP is a mid-cap income-oriented stock. KO, PEP pay a dividend while ENGN, TGTX, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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