Biotechnology
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Side-by-side financial analysisStock Comparison
ENGN vs TGTX vs KO vs IMVT vs PEP
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Beverages - Non-Alcoholic
Biotechnology
Beverages - Non-Alcoholic
ENGN vs TGTX vs KO vs IMVT vs PEP — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Beverages - Non-Alcoholic | Biotechnology | Beverages - Non-Alcoholic |
| Market Cap | $83M | $7.58B | $355.61B | $6.90B | $197.17B |
| Revenue (TTM) | — | $700M | $49.28B | $0.00 | $93.92B |
| Net Income (TTM) | $-122M | $462M | $13.70B | $-506M | $8.24B |
| Gross Margin | — | 83.0% | 61.7% | — | 54.1% |
| Operating Margin | — | 21.3% | 29.3% | — | 12.2% |
| Forward P/E | — | 35.9x | 25.3x | — | 16.7x |
| Total Debt | $32M | $261M | $45.49B | $72K | $49.90B |
| Cash & Equiv. | $50M | $79M | $10.27B | $902M | $9.16B |
ENGN vs TGTX vs KO vs IMVT vs PEP — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Nov 23 | Jun 26 | Return |
|---|---|---|---|
| enGene Holdings Inc. (ENGN) | 100 | 21.1 | -78.9% |
| TG Therapeutics, In… (TGTX) | 100 | 386.6 | +286.6% |
| The Coca-Cola Compa… (KO) | 100 | 141.4 | +41.4% |
| Immunovant, Inc. (IMVT) | 100 | 85.9 | -14.1% |
| PepsiCo, Inc. (PEP) | 100 | 85.7 | -14.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ENGN vs TGTX vs KO vs IMVT vs PEP
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ENGN lags the leaders in this set but could rank higher in a more targeted comparison.
TGTX carries the broadest edge in this set and is the clearest fit for growth exposure and defensive.
- Rev growth 87.3%, EPS growth 17.5%, 3Y rev CAGR 5.0%
- Beta 0.65, current ratio 4.10x
- 87.3% revenue growth vs ENGN's -77.3%
- 66.0% margin vs IMVT's 2.6%
KO is the clearest fit if your priority is valuation efficiency.
- PEG 2.26 vs PEP's 5.11
IMVT ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.
- 237.9% 10Y total return vs TGTX's 6.1%
- Lower volatility, beta 1.66, Low D/E 0.0%, current ratio 9.09x
- +110.9% vs ENGN's -50.2%
PEP is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 54 yrs, beta -0.11, yield 3.9%
- Better valuation composite
- 3.9% yield, 54-year raise streak, vs KO's 2.5%, (3 stocks pay no dividend)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 87.3% revenue growth vs ENGN's -77.3% | |
| Value | Better valuation composite | |
| Quality / Margins | 66.0% margin vs IMVT's 2.6% | |
| Stability / Safety | Beta 0.65 vs ENGN's 2.26 | |
| Dividends | 3.9% yield, 54-year raise streak, vs KO's 2.5%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +110.9% vs ENGN's -50.2% | |
| Efficiency (ROA) | 42.8% ROA vs IMVT's -62.2% |
ENGN vs TGTX vs KO vs IMVT vs PEP — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
ENGN vs TGTX vs KO vs IMVT vs PEP — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
TGTX leads in 3 of 6 categories
PEP leads 1 • KO leads 1 • ENGN leads 0 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
TGTX leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PEP and IMVT operate at a comparable scale, with $93.9B and $0 in trailing revenue. TGTX is the more profitable business, keeping 66.0% of every revenue dollar as net income compared to PEP's 8.8%. On growth, TGTX holds the edge at +69.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | — | $700M | $49.3B | $0 | $93.9B |
| EBITDAEarnings before interest/tax | -$127M | $150M | $15.5B | -$532M | $14.3B |
| Net IncomeAfter-tax profit | -$122M | $462M | $13.7B | -$506M | $8.2B |
| Free Cash FlowCash after capex | -$104M | -$14M | $12.6B | -$407M | $7.7B |
| Gross MarginGross profit ÷ Revenue | — | +83.0% | +61.7% | — | +54.1% |
| Operating MarginEBIT ÷ Revenue | — | +21.3% | +29.3% | — | +12.2% |
| Net MarginNet income ÷ Revenue | — | +66.0% | +27.8% | — | +8.8% |
| FCF MarginFCF ÷ Revenue | — | -2.0% | +25.5% | — | +8.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +69.6% | +12.1% | — | +5.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +8.3% | +2.9% | +18.2% | -14.1% | +66.7% |
Valuation Metrics
PEP leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 17.9x trailing earnings, TGTX trades at a 34% valuation discount to KO's 27.2x P/E. Adjusting for growth (PEG ratio), KO offers better value at 2.43x vs PEP's 7.37x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $83M | $7.6B | $355.6B | $6.9B | $197.2B |
| Enterprise ValueMkt cap + debt − cash | $65M | $7.8B | $390.8B | $6.0B | $237.9B |
| Trailing P/EPrice ÷ TTM EPS | -0.71x | 17.88x | 27.18x | -12.14x | 24.05x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 35.88x | 25.27x | — | 16.68x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.43x | — | 7.37x |
| EV / EBITDAEnterprise value multiple | — | 62.82x | 26.39x | — | 16.63x |
| Price / SalesMarket cap ÷ Revenue | — | 12.30x | 7.42x | — | 2.10x |
| Price / BookPrice ÷ Book value/share | 0.49x | 12.33x | 10.40x | 7.19x | 9.63x |
| Price / FCFMarket cap ÷ FCF | — | — | 67.15x | — | 25.70x |
Profitability & Efficiency
TGTX leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
TGTX delivers a 87.4% return on equity — every $100 of shareholder capital generates $87 in annual profit, vs $-68 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to PEP's 2.43x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ENGN's 1/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -55.8% | +87.4% | +41.1% | -68.2% | +40.1% |
| ROA (TTM)Return on assets | -45.7% | +42.8% | +13.1% | -62.2% | +7.7% |
| ROICReturn on invested capital | -67.4% | +16.4% | +15.8% | — | +14.9% |
| ROCEReturn on capital employed | -50.7% | +17.7% | +17.3% | -68.3% | +16.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 | 7 | 2 | 5 |
| Debt / EquityFinancial leverage | 0.19x | 0.40x | 1.33x | 0.00x | 2.43x |
| Net DebtTotal debt minus cash | -$18M | $182M | $35.2B | -$902M | $40.7B |
| Cash & Equiv.Liquid assets | $50M | $79M | $10.3B | $902M | $9.2B |
| Total DebtShort + long-term debt | $32M | $261M | $45.5B | $72,000 | $49.9B |
| Interest CoverageEBIT ÷ Interest expense | -40.18x | 5.67x | 10.70x | — | 10.34x |
Total Returns (Dividends Reinvested)
TGTX leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $810 for ENGN. Over the past 12 months, IMVT leads with a +110.9% total return vs ENGN's -50.2%. The 3-year compound annual growth rate (CAGR) favors TGTX at 23.6% vs ENGN's -56.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -81.7% | +69.1% | +20.3% | +29.8% | +3.5% |
| 1-Year ReturnPast 12 months | -50.2% | +32.5% | +17.2% | +110.9% | +13.4% |
| 3-Year ReturnCumulative with dividends | -91.9% | +89.0% | +47.0% | +55.0% | -11.7% |
| 5-Year ReturnCumulative with dividends | -91.9% | +29.3% | +65.6% | +213.0% | +14.3% |
| 10-Year ReturnCumulative with dividends | -91.9% | +605.4% | +121.1% | +237.9% | +82.3% |
| CAGR (3Y)Annualised 3-year return | -56.7% | +23.6% | +13.7% | +15.7% | -4.1% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ENGN's 2.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs ENGN's 13.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.26x | 0.65x | -0.20x | 1.66x | -0.11x |
| 52-Week HighHighest price in past year | $12.25 | $50.41 | $84.04 | $36.27 | $171.48 |
| 52-Week LowLowest price in past year | $1.40 | $25.28 | $65.35 | $14.32 | $127.60 |
| % of 52W HighCurrent price vs 52-week peak | +13.2% | +98.2% | +98.3% | +92.7% | +84.1% |
| RSI (14)Momentum oscillator 0–100 | 29.8 | 76.1 | 60.6 | 57.9 | 41.6 |
| Avg Volume (50D)Average daily shares traded | 1.9M | 2.0M | 12.7M | 1.9M | 6.0M |
Analyst Outlook
Evenly matched — KO and PEP each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ENGN as "Hold", TGTX as "Buy", KO as "Buy", IMVT as "Buy", PEP as "Hold". Consensus price targets imply 332.1% upside for ENGN (target: $7) vs 4.2% for KO (target: $86). For income investors, PEP offers the higher dividend yield at 3.86% vs KO's 2.46%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | $7.00 | $54.50 | $86.13 | $43.67 | $167.88 |
| # AnalystsCovering analysts | 9 | 13 | 48 | 23 | 45 |
| Dividend YieldAnnual dividend ÷ price | — | — | +2.5% | — | +3.9% |
| Dividend StreakConsecutive years of raises | 0 | 0 | 56 | — | 54 |
| Dividend / ShareAnnual DPS | — | — | $2.04 | — | $5.57 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.2% | +0.2% | 0.0% | +0.5% |
TGTX leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PEP leads in 1 (Valuation Metrics). 1 tied.
ENGN vs TGTX vs KO vs IMVT vs PEP: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ENGN or TGTX or KO or IMVT or PEP a better buy right now?
For growth investors, TG Therapeutics, Inc.
(TGTX) is the stronger pick with 87. 3% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). TG Therapeutics, Inc. (TGTX) offers the better valuation at 17. 9x trailing P/E (35. 9x forward), making it the more compelling value choice. Analysts rate TG Therapeutics, Inc. (TGTX) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ENGN or TGTX or KO or IMVT or PEP?
On trailing P/E, TG Therapeutics, Inc.
(TGTX) is the cheapest at 17. 9x versus The Coca-Cola Company at 27. 2x. On forward P/E, PepsiCo, Inc. is actually cheaper at 16. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: The Coca-Cola Company wins at 2. 26x versus PepsiCo, Inc. 's 5. 11x.
03Which is the better long-term investment — ENGN or TGTX or KO or IMVT or PEP?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +213. 0%, compared to -91. 9% for enGene Holdings Inc. (ENGN). Over 10 years, the gap is even starker: TGTX returned +605. 4% versus ENGN's -91. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ENGN or TGTX or KO or IMVT or PEP?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus enGene Holdings Inc. 's 2. 26β — meaning ENGN is approximately -1227% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 2% for PepsiCo, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ENGN or TGTX or KO or IMVT or PEP?
By revenue growth (latest reported year), TG Therapeutics, Inc.
(TGTX) is pulling ahead at 87. 3% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: TG Therapeutics, Inc. grew EPS 1747% year-over-year, compared to -56. 8% for enGene Holdings Inc.. Over a 3-year CAGR, TGTX leads at 504. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ENGN or TGTX or KO or IMVT or PEP?
TG Therapeutics, Inc.
(TGTX) is the more profitable company, earning 72. 6% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 72. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — TGTX leads at 83. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ENGN or TGTX or KO or IMVT or PEP more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, The Coca-Cola Company (KO) is the more undervalued stock at a PEG of 2. 26x versus PepsiCo, Inc. 's 5. 11x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, PepsiCo, Inc. (PEP) trades at 16. 7x forward P/E versus 35. 9x for TG Therapeutics, Inc. — 19. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ENGN: 332. 1% to $7. 00.
08Which pays a better dividend — ENGN or TGTX or KO or IMVT or PEP?
In this comparison, PEP (3.
9% yield), KO (2. 5% yield) pay a dividend. ENGN, TGTX, IMVT do not pay a meaningful dividend and should not be held primarily for income.
09Is ENGN or TGTX or KO or IMVT or PEP better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). enGene Holdings Inc. (ENGN) carries a higher beta of 2. 26 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, ENGN: -91. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ENGN and TGTX and KO and IMVT and PEP?
These companies operate in different sectors (ENGN (Healthcare) and TGTX (Healthcare) and KO (Consumer Defensive) and IMVT (Healthcare) and PEP (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: ENGN is a small-cap quality compounder stock; TGTX is a small-cap high-growth stock; KO is a large-cap quality compounder stock; IMVT is a small-cap quality compounder stock; PEP is a mid-cap income-oriented stock. KO, PEP pay a dividend while ENGN, TGTX, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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