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Stock Comparison

ESTA vs NVCR vs INMD vs SYK vs BSX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ESTA
Establishment Labs Holdings Inc.

Medical - Devices

HealthcareNASDAQ • CR
Market Cap$2.12B
5Y Perf.+264.7%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-73.5%
INMD
InMode Ltd.

Medical - Devices

HealthcareNASDAQ • IL
Market Cap$882M
5Y Perf.-4.8%
SYK
Stryker Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$112.69B
5Y Perf.+45.8%
BSX
Boston Scientific Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$84.08B
5Y Perf.+42.0%

ESTA vs NVCR vs INMD vs SYK vs BSX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ESTA logoESTA
NVCR logoNVCR
INMD logoINMD
SYK logoSYK
BSX logoBSX
IndustryMedical - DevicesMedical - Instruments & SuppliesMedical - DevicesMedical - DevicesMedical - Devices
Market Cap$2.12B$1.92B$882M$112.69B$84.08B
Revenue (TTM)$211M$674M$375M$25.12B$20.07B
Net Income (TTM)$-51M$-173M$87M$3.25B$2.89B
Gross Margin69.3%75.2%77.8%63.5%69.0%
Operating Margin-18.5%-27.2%21.3%22.4%19.8%
Forward P/E10.3x19.1x16.0x
Total Debt$264M$290M$13M$14.86B$12.42B
Cash & Equiv.$76M$103M$303M$4.01B$2.04B

ESTA vs NVCR vs INMD vs SYK vs BSXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ESTA
NVCR
INMD
SYK
BSX
StockMay 20May 26Return
Establishment Labs … (ESTA)100364.7+264.7%
NovoCure Limited (NVCR)10026.5-73.5%
InMode Ltd. (INMD)10095.2-4.8%
Stryker Corporation (SYK)100145.8+45.8%
Boston Scientific C… (BSX)100142.0+42.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: ESTA vs NVCR vs INMD vs SYK vs BSX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INMD leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Establishment Labs Holdings Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. SYK and BSX also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
ESTA
Establishment Labs Holdings Inc.
The Long-Run Compounder

ESTA is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 191.0% 10Y total return vs SYK's 187.1%
  • 27.1% revenue growth vs INMD's -6.2%
  • +116.5% vs BSX's -46.0%
Best for: long-term compounding
NVCR
NovoCure Limited
The Healthcare Pick

Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
INMD
InMode Ltd.
The Defensive Pick

INMD carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and valuation efficiency.

  • Lower volatility, beta 1.04, Low D/E 1.9%, current ratio 9.88x
  • PEG 1.04 vs SYK's 1.28
  • Beta 1.04, current ratio 9.88x
  • Lower P/E (10.3x vs 16.0x)
Best for: sleep-well-at-night and valuation efficiency
SYK
Stryker Corporation
The Income Pick

SYK ranks third and is worth considering specifically for income & stability.

  • Dividend streak 34 yrs, beta 0.55, yield 1.1%
  • 1.1% yield; 34-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability
BSX
Boston Scientific Corporation
The Growth Play

BSX is the clearest fit if your priority is growth exposure.

  • Rev growth 19.9%, EPS growth 55.2%, 3Y rev CAGR 16.5%
  • Beta 0.34 vs NVCR's 2.20, lower leverage
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthESTA logoESTA27.1% revenue growth vs INMD's -6.2%
ValueINMD logoINMDLower P/E (10.3x vs 16.0x)
Quality / MarginsINMD logoINMD23.3% margin vs NVCR's -25.7%
Stability / SafetyBSX logoBSXBeta 0.34 vs NVCR's 2.20, lower leverage
DividendsSYK logoSYK1.1% yield; 34-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)ESTA logoESTA+116.5% vs BSX's -46.0%
Efficiency (ROA)INMD logoINMD11.8% ROA vs NVCR's -16.5%, ROIC 13.5% vs -16.4%

ESTA vs NVCR vs INMD vs SYK vs BSX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ESTAEstablishment Labs Holdings Inc.

Segment breakdown not available.

NVCRNovoCure Limited

Segment breakdown not available.

INMDInMode Ltd.
FY 2025
Capital Equipment
100.0%$289M
SYKStryker Corporation
FY 2025
MedSurg
62.3%$15.6B
Orthopaedics
37.7%$9.5B
BSXBoston Scientific Corporation
FY 2025
Cardiovascular
66.0%$13.3B
MedSurg
34.0%$6.8B

ESTA vs NVCR vs INMD vs SYK vs BSX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINMDLAGGINGNVCR

Income & Cash Flow (Last 12 Months)

INMD leads this category, winning 3 of 6 comparable metrics.

SYK is the larger business by revenue, generating $25.1B annually — 119.0x ESTA's $211M. INMD is the more profitable business, keeping 23.3% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, ESTA holds the edge at +45.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricESTA logoESTAEstablishment Lab…NVCR logoNVCRNovoCure LimitedINMD logoINMDInMode Ltd.SYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
RevenueTrailing 12 months$211M$674M$375M$25.1B$20.1B
EBITDAEarnings before interest/tax-$32M-$165M$81M$6.3B$4.7B
Net IncomeAfter-tax profit-$51M-$173M$87M$3.2B$2.9B
Free Cash FlowCash after capex-$57M-$48M$91M$4.3B$3.6B
Gross MarginGross profit ÷ Revenue+69.3%+75.2%+77.8%+63.5%+69.0%
Operating MarginEBIT ÷ Revenue-18.5%-27.2%+21.3%+22.4%+19.8%
Net MarginNet income ÷ Revenue-24.2%-25.7%+23.3%+12.9%+14.4%
FCF MarginFCF ÷ Revenue-27.2%-7.1%+24.2%+17.1%+18.1%
Rev. Growth (YoY)Latest quarter vs prior year+45.2%+12.3%+5.3%+11.4%+15.9%
EPS Growth (YoY)Latest quarter vs prior year+92.6%-100.0%-30.8%+56.0%+18.5%
INMD leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

INMD leads this category, winning 6 of 7 comparable metrics.

At 9.7x trailing earnings, INMD trades at a 72% valuation discount to SYK's 35.0x P/E. Adjusting for growth (PEG ratio), INMD offers better value at 0.98x vs SYK's 2.36x — a lower PEG means you pay less per unit of expected earnings growth.

MetricESTA logoESTAEstablishment Lab…NVCR logoNVCRNovoCure LimitedINMD logoINMDInMode Ltd.SYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
Market CapShares × price$2.1B$1.9B$882M$112.7B$84.1B
Enterprise ValueMkt cap + debt − cash$2.3B$2.1B$593M$123.5B$94.5B
Trailing P/EPrice ÷ TTM EPS-41.88x-13.80x9.73x35.03x29.16x
Forward P/EPrice ÷ next-FY EPS est.10.32x19.06x15.96x
PEG RatioP/E ÷ EPS growth rate0.98x2.36x
EV / EBITDAEnterprise value multiple6.88x20.31x25.30x
Price / SalesMarket cap ÷ Revenue10.03x2.92x2.38x4.49x4.19x
Price / BookPrice ÷ Book value/share90.61x5.51x1.33x5.02x3.46x
Price / FCFMarket cap ÷ FCF10.46x26.31x22.99x
INMD leads this category, winning 6 of 7 comparable metrics.

Profitability & Efficiency

INMD leads this category, winning 5 of 9 comparable metrics.

SYK delivers a 15.0% return on equity — every $100 of shareholder capital generates $15 in annual profit, vs $-2 for ESTA. INMD carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ESTA's 11.23x. On the Piotroski fundamental quality scale (0–9), BSX scores 7/9 vs INMD's 3/9, reflecting strong financial health.

MetricESTA logoESTAEstablishment Lab…NVCR logoNVCRNovoCure LimitedINMD logoINMDInMode Ltd.SYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
ROE (TTM)Return on equity-2.0%-50.8%+13.3%+15.0%+12.4%
ROA (TTM)Return on assets-15.0%-16.5%+11.8%+6.9%+6.9%
ROICReturn on invested capital-14.6%-16.4%+13.5%+11.4%+8.8%
ROCEReturn on capital employed-14.1%-28.9%+12.1%+13.0%+11.1%
Piotroski ScoreFundamental quality 0–945367
Debt / EquityFinancial leverage11.23x0.85x0.02x0.66x0.51x
Net DebtTotal debt minus cash$189M$187M-$289M$10.8B$10.4B
Cash & Equiv.Liquid assets$76M$103M$303M$4.0B$2.0B
Total DebtShort + long-term debt$264M$290M$13M$14.9B$12.4B
Interest CoverageEBIT ÷ Interest expense-1.30x-96.80x6.72x11.03x
INMD leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

BSX leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in BSX five years ago would be worth $13,117 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, ESTA leads with a +116.5% total return vs BSX's -46.0%. The 3-year compound annual growth rate (CAGR) favors BSX at 2.1% vs NVCR's -37.6% — a key indicator of consistent wealth creation.

MetricESTA logoESTAEstablishment Lab…NVCR logoNVCRNovoCure LimitedINMD logoINMDInMode Ltd.SYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
YTD ReturnYear-to-date+4.6%+28.3%-5.9%-15.2%-40.3%
1-Year ReturnPast 12 months+116.5%+1.1%-2.1%-22.5%-46.0%
3-Year ReturnCumulative with dividends+6.4%-75.7%-60.2%+5.5%+6.5%
5-Year ReturnCumulative with dividends+0.6%-91.3%-63.9%+21.5%+31.2%
10-Year ReturnCumulative with dividends+191.0%+30.3%+105.0%+187.1%+155.5%
CAGR (3Y)Annualised 3-year return+2.1%-37.6%-26.4%+1.8%+2.1%
BSX leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ESTA and BSX each lead in 1 of 2 comparable metrics.

BSX is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ESTA currently trades 86.5% from its 52-week high vs BSX's 51.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricESTA logoESTAEstablishment Lab…NVCR logoNVCRNovoCure LimitedINMD logoINMDInMode Ltd.SYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
Beta (5Y)Sensitivity to S&P 5001.27x2.15x1.00x0.52x0.30x
52-Week HighHighest price in past year$83.31$20.06$16.74$404.87$109.50
52-Week LowLowest price in past year$32.75$9.82$12.72$289.91$54.98
% of 52W HighCurrent price vs 52-week peak+86.5%+83.9%+83.2%+72.7%+51.7%
RSI (14)Momentum oscillator 0–10066.869.839.824.333.2
Avg Volume (50D)Average daily shares traded455K1.5M804K2.1M15.5M
Evenly matched — ESTA and BSX each lead in 1 of 2 comparable metrics.

Analyst Outlook

SYK leads this category, winning 1 of 1 comparable metric.

Analyst consensus: ESTA as "Buy", NVCR as "Buy", INMD as "Hold", SYK as "Buy", BSX as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 18.0% for ESTA (target: $85). SYK is the only dividend payer here at 1.14% yield — a key consideration for income-focused portfolios.

MetricESTA logoESTAEstablishment Lab…NVCR logoNVCRNovoCure LimitedINMD logoINMDInMode Ltd.SYK logoSYKStryker Corporati…BSX logoBSXBoston Scientific…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuyBuy
Price TargetConsensus 12-month target$85.00$33.50$17.00$389.62$91.33
# AnalystsCovering analysts1415115043
Dividend YieldAnnual dividend ÷ price+1.1%
Dividend StreakConsecutive years of raises340
Dividend / ShareAnnual DPS$3.36
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+14.5%0.0%0.0%
SYK leads this category, winning 1 of 1 comparable metric.
Key Takeaway

INMD leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). BSX leads in 1 (Total Returns). 1 tied.

Best OverallInMode Ltd. (INMD)Leads 3 of 6 categories
Loading custom metrics...

ESTA vs NVCR vs INMD vs SYK vs BSX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ESTA or NVCR or INMD or SYK or BSX a better buy right now?

For growth investors, Establishment Labs Holdings Inc.

(ESTA) is the stronger pick with 27. 1% revenue growth year-over-year, versus -6. 2% for InMode Ltd. (INMD). InMode Ltd. (INMD) offers the better valuation at 9. 7x trailing P/E (10. 3x forward), making it the more compelling value choice. Analysts rate Establishment Labs Holdings Inc. (ESTA) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ESTA or NVCR or INMD or SYK or BSX?

On trailing P/E, InMode Ltd.

(INMD) is the cheapest at 9. 7x versus Stryker Corporation at 35. 0x. On forward P/E, InMode Ltd. is actually cheaper at 10. 3x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: InMode Ltd. wins at 1. 04x versus Stryker Corporation's 1. 28x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — ESTA or NVCR or INMD or SYK or BSX?

Over the past 5 years, Boston Scientific Corporation (BSX) delivered a total return of +31.

2%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: ESTA returned +190. 0% versus NVCR's +38. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ESTA or NVCR or INMD or SYK or BSX?

By beta (market sensitivity over 5 years), Boston Scientific Corporation (BSX) is the lower-risk stock at 0.

30β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 616% more volatile than BSX relative to the S&P 500. On balance sheet safety, InMode Ltd. (INMD) carries a lower debt/equity ratio of 2% versus 11% for Establishment Labs Holdings Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ESTA or NVCR or INMD or SYK or BSX?

By revenue growth (latest reported year), Establishment Labs Holdings Inc.

(ESTA) is pulling ahead at 27. 1% versus -6. 2% for InMode Ltd. (INMD). On earnings-per-share growth, the picture is similar: Boston Scientific Corporation grew EPS 55. 2% year-over-year, compared to -36. 4% for InMode Ltd.. Over a 3-year CAGR, BSX leads at 16. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ESTA or NVCR or INMD or SYK or BSX?

InMode Ltd.

(INMD) is the more profitable company, earning 25. 3% net margin versus -24. 2% for Establishment Labs Holdings Inc. — meaning it keeps 25. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INMD leads at 23. 0% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — INMD leads at 78. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ESTA or NVCR or INMD or SYK or BSX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, InMode Ltd. (INMD) is the more undervalued stock at a PEG of 1. 04x versus Stryker Corporation's 1. 28x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, InMode Ltd. (INMD) trades at 10. 3x forward P/E versus 19. 1x for Stryker Corporation — 8. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.

08

Which pays a better dividend — ESTA or NVCR or INMD or SYK or BSX?

In this comparison, SYK (1.

1% yield) pays a dividend. ESTA, NVCR, INMD, BSX do not pay a meaningful dividend and should not be held primarily for income.

09

Is ESTA or NVCR or INMD or SYK or BSX better for a retirement portfolio?

For long-horizon retirement investors, Stryker Corporation (SYK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

52), 1. 1% yield, +179. 2% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SYK: +179. 2%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ESTA and NVCR and INMD and SYK and BSX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ESTA is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock; INMD is a small-cap deep-value stock; SYK is a mid-cap quality compounder stock; BSX is a mid-cap high-growth stock. SYK pays a dividend while ESTA, NVCR, INMD, BSX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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High-Growth Compounder

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Beat Both

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Revenue Growth>
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(ESTA: 45.2% · NVCR: 12.3%)

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