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GKOS vs ATRC vs NVCR vs IRTC vs ABT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
GKOS
Glaukos Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$7.81B
5Y Perf.+242.5%
ATRC
AtriCure, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$1.33B
5Y Perf.-45.0%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$2.04B
5Y Perf.-73.5%
IRTC
iRhythm Technologies, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$3.96B
5Y Perf.-2.9%
ABT
Abbott Laboratories

Medical - Devices

HealthcareNYSE • US
Market Cap$146.59B
5Y Perf.-11.2%

GKOS vs ATRC vs NVCR vs IRTC vs ABT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
GKOS logoGKOS
ATRC logoATRC
NVCR logoNVCR
IRTC logoIRTC
ABT logoABT
IndustryMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - DevicesMedical - Devices
Market Cap$7.81B$1.33B$2.04B$3.96B$146.59B
Revenue (TTM)$551M$552M$674M$788M$43.84B
Net Income (TTM)$-189M$-5M$-173M$-28M$13.98B
Gross Margin78.1%75.5%75.2%71.0%54.0%
Operating Margin-15.6%-0.4%-27.2%-3.3%17.8%
Forward P/E428.7x27422.7x15.4x
Total Debt$140M$88M$290M$731M$15.28B
Cash & Equiv.$91M$167M$103M$236M$7.62B

GKOS vs ATRC vs NVCR vs IRTC vs ABTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

GKOS
ATRC
NVCR
IRTC
ABT
StockMay 20May 26Return
Glaukos Corporation (GKOS)100342.5+242.5%
AtriCure, Inc. (ATRC)10055.0-45.0%
NovoCure Limited (NVCR)10026.5-73.5%
iRhythm Technologie… (IRTC)10097.1-2.9%
Abbott Laboratories (ABT)10088.8-11.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: GKOS vs ATRC vs NVCR vs IRTC vs ABT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABT leads in 5 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Glaukos Corporation is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
GKOS
Glaukos Corporation
The Long-Run Compounder

GKOS is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 454.5% 10Y total return vs IRTC's 363.2%
  • 32.3% revenue growth vs ABT's 4.6%
  • +47.5% vs ABT's -35.3%
Best for: long-term compounding
ATRC
AtriCure, Inc.
The Defensive Pick

ATRC ranks third and is worth considering specifically for sleep-well-at-night.

  • Lower volatility, beta 0.95, Low D/E 17.9%, current ratio 3.96x
Best for: sleep-well-at-night
NVCR
NovoCure Limited
The Healthcare Pick

NVCR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
IRTC
iRhythm Technologies, Inc.
The Growth Play

IRTC is the clearest fit if your priority is growth exposure and defensive.

  • Rev growth 26.2%, EPS growth 61.7%, 3Y rev CAGR 22.1%
  • Beta 0.73, current ratio 4.63x
Best for: growth exposure and defensive
ABT
Abbott Laboratories
The Income Pick

ABT carries the broadest edge in this set and is the clearest fit for income & stability.

  • Dividend streak 11 yrs, beta 0.22, yield 2.6%
  • Lower P/E (15.4x vs 27422.7x)
  • 31.9% margin vs GKOS's -34.3%
  • Beta 0.22 vs NVCR's 2.15, lower leverage
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthGKOS logoGKOS32.3% revenue growth vs ABT's 4.6%
ValueABT logoABTLower P/E (15.4x vs 27422.7x)
Quality / MarginsABT logoABT31.9% margin vs GKOS's -34.3%
Stability / SafetyABT logoABTBeta 0.22 vs NVCR's 2.15, lower leverage
DividendsABT logoABT2.6% yield; 11-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)GKOS logoGKOS+47.5% vs ABT's -35.3%
Efficiency (ROA)ABT logoABT16.6% ROA vs GKOS's -20.1%, ROIC 9.9% vs -9.2%

GKOS vs ATRC vs NVCR vs IRTC vs ABT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GKOSGlaukos Corporation
FY 2019
Glaucoma
97.5%$231M
Corneal Health
2.5%$6M
ATRCAtriCure, Inc.
FY 2025
Shipping and Handling
100.0%$2M
NVCRNovoCure Limited

Segment breakdown not available.

IRTCiRhythm Technologies, Inc.
FY 2025
Commercial Payors
52.5%$392M
Centers For Medicare And Medicaid
24.0%$179M
Healthcare Institutions
16.8%$126M
Non-contracted Third-party Payors
6.7%$50M
ABTAbbott Laboratories
FY 2024
Medical Devices
45.3%$19.0B
Diagnostic Products
22.3%$9.3B
Nutritional Products
20.1%$8.4B
Established Pharmaceutical Products
12.4%$5.2B

GKOS vs ATRC vs NVCR vs IRTC vs ABT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABTLAGGINGIRTC

Income & Cash Flow (Last 12 Months)

ABT leads this category, winning 3 of 6 comparable metrics.

ABT is the larger business by revenue, generating $43.8B annually — 79.5x GKOS's $551M. ABT is the more profitable business, keeping 31.9% of every revenue dollar as net income compared to GKOS's -34.3%. On growth, GKOS holds the edge at +41.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…ABT logoABTAbbott Laboratori…
RevenueTrailing 12 months$551M$552M$674M$788M$43.8B
EBITDAEarnings before interest/tax-$40M$13M-$165M-$6M$10.9B
Net IncomeAfter-tax profit-$189M-$5M-$173M-$28M$14.0B
Free Cash FlowCash after capex-$18M$54M-$48M$19M$6.9B
Gross MarginGross profit ÷ Revenue+78.1%+75.5%+75.2%+71.0%+54.0%
Operating MarginEBIT ÷ Revenue-15.6%-0.4%-27.2%-3.3%+17.8%
Net MarginNet income ÷ Revenue-34.3%-0.8%-25.7%-3.5%+31.9%
FCF MarginFCF ÷ Revenue-3.4%+9.7%-7.1%+2.4%+15.8%
Rev. Growth (YoY)Latest quarter vs prior year+41.2%+14.3%+12.3%+25.7%+6.9%
EPS Growth (YoY)Latest quarter vs prior year-6.3%+101.6%-100.0%+55.7%0.0%
ABT leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — ATRC and ABT each lead in 3 of 6 comparable metrics.

On an enterprise value basis, ABT's 15.4x EV/EBITDA is more attractive than ATRC's 73.2x.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…ABT logoABTAbbott Laboratori…
Market CapShares × price$7.8B$1.3B$2.0B$4.0B$146.6B
Enterprise ValueMkt cap + debt − cash$7.9B$1.3B$2.2B$4.5B$154.2B
Trailing P/EPrice ÷ TTM EPS-40.71x-109.50x-14.66x-86.81x11.03x
Forward P/EPrice ÷ next-FY EPS est.428.71x27422.73x15.40x
PEG RatioP/E ÷ EPS growth rate0.37x
EV / EBITDAEnterprise value multiple73.24x15.36x
Price / SalesMarket cap ÷ Revenue15.40x2.49x3.11x5.31x3.49x
Price / BookPrice ÷ Book value/share11.64x2.55x5.86x25.28x3.08x
Price / FCFMarket cap ÷ FCF27.56x114.83x23.08x
Evenly matched — ATRC and ABT each lead in 3 of 6 comparable metrics.

Profitability & Efficiency

ABT leads this category, winning 6 of 9 comparable metrics.

ABT delivers a 27.3% return on equity — every $100 of shareholder capital generates $27 in annual profit, vs $-51 for NVCR. ATRC carries lower financial leverage with a 0.18x debt-to-equity ratio, signaling a more conservative balance sheet compared to IRTC's 4.79x. On the Piotroski fundamental quality scale (0–9), ABT scores 7/9 vs GKOS's 3/9, reflecting strong financial health.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…ABT logoABTAbbott Laboratori…
ROE (TTM)Return on equity-26.5%-1.0%-50.8%-20.6%+27.3%
ROA (TTM)Return on assets-20.1%-0.7%-16.5%-2.8%+16.6%
ROICReturn on invested capital-9.2%-0.6%-16.4%-5.2%+9.9%
ROCEReturn on capital employed-10.3%-0.6%-28.9%-4.4%+10.8%
Piotroski ScoreFundamental quality 0–935567
Debt / EquityFinancial leverage0.21x0.18x0.85x4.79x0.32x
Net DebtTotal debt minus cash$49M-$79M$187M$495M$7.7B
Cash & Equiv.Liquid assets$91M$167M$103M$236M$7.6B
Total DebtShort + long-term debt$140M$88M$290M$731M$15.3B
Interest CoverageEBIT ÷ Interest expense-18.69x0.47x-96.80x-1.48x19.22x
ABT leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GKOS leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in GKOS five years ago would be worth $17,474 today (with dividends reinvested), compared to $983 for NVCR. Over the past 12 months, GKOS leads with a +47.5% total return vs ABT's -35.3%. The 3-year compound annual growth rate (CAGR) favors GKOS at 31.5% vs NVCR's -36.4% — a key indicator of consistent wealth creation.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…ABT logoABTAbbott Laboratori…
YTD ReturnYear-to-date+20.6%-33.1%+36.4%-31.1%-31.1%
1-Year ReturnPast 12 months+47.5%-15.7%+2.6%-11.9%-35.3%
3-Year ReturnCumulative with dividends+127.6%-45.0%-74.2%-5.4%-17.8%
5-Year ReturnCumulative with dividends+74.7%-64.2%-90.2%+54.8%-20.2%
10-Year ReturnCumulative with dividends+454.5%+84.4%+38.5%+363.2%+166.6%
CAGR (3Y)Annualised 3-year return+31.5%-18.1%-36.4%-1.8%-6.3%
GKOS leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — GKOS and ABT each lead in 1 of 2 comparable metrics.

ABT is the less volatile stock with a 0.22 beta — it tends to amplify market swings less than NVCR's 2.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GKOS currently trades 91.0% from its 52-week high vs IRTC's 56.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…ABT logoABTAbbott Laboratori…
Beta (5Y)Sensitivity to S&P 5001.16x0.95x2.15x0.73x0.22x
52-Week HighHighest price in past year$146.75$43.18$20.06$212.00$139.06
52-Week LowLowest price in past year$73.16$26.10$9.82$112.31$84.08
% of 52W HighCurrent price vs 52-week peak+91.0%+60.9%+89.2%+56.9%+60.6%
RSI (14)Momentum oscillator 0–10061.544.070.953.326.3
Avg Volume (50D)Average daily shares traded674K678K1.4M525K10.6M
Evenly matched — GKOS and ABT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: GKOS as "Buy", ATRC as "Buy", NVCR as "Buy", IRTC as "Buy", ABT as "Buy". Consensus price targets imply 95.3% upside for ATRC (target: $51) vs 9.8% for GKOS (target: $147). ABT is the only dividend payer here at 2.60% yield — a key consideration for income-focused portfolios.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…ABT logoABTAbbott Laboratori…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$146.67$51.33$33.50$193.67$128.71
# AnalystsCovering analysts2419151941
Dividend YieldAnnual dividend ÷ price+2.6%
Dividend StreakConsecutive years of raises11
Dividend / ShareAnnual DPS$2.19
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.8%0.0%0.0%+0.9%
Insufficient data to determine a leader in this category.
Key Takeaway

ABT leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). GKOS leads in 1 (Total Returns). 2 tied.

Best OverallAbbott Laboratories (ABT)Leads 2 of 6 categories
Loading custom metrics...

GKOS vs ATRC vs NVCR vs IRTC vs ABT: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is GKOS or ATRC or NVCR or IRTC or ABT a better buy right now?

For growth investors, Glaukos Corporation (GKOS) is the stronger pick with 32.

3% revenue growth year-over-year, versus 4. 6% for Abbott Laboratories (ABT). Abbott Laboratories (ABT) offers the better valuation at 11. 0x trailing P/E (15. 4x forward), making it the more compelling value choice. Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — GKOS or ATRC or NVCR or IRTC or ABT?

On forward P/E, Abbott Laboratories is actually cheaper at 15.

4x.

03

Which is the better long-term investment — GKOS or ATRC or NVCR or IRTC or ABT?

Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +74.

7%, compared to -90. 2% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: GKOS returned +454. 5% versus NVCR's +38. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — GKOS or ATRC or NVCR or IRTC or ABT?

By beta (market sensitivity over 5 years), Abbott Laboratories (ABT) is the lower-risk stock at 0.

22β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 894% more volatile than ABT relative to the S&P 500. On balance sheet safety, AtriCure, Inc. (ATRC) carries a lower debt/equity ratio of 18% versus 5% for iRhythm Technologies, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — GKOS or ATRC or NVCR or IRTC or ABT?

By revenue growth (latest reported year), Glaukos Corporation (GKOS) is pulling ahead at 32.

3% versus 4. 6% for Abbott Laboratories (ABT). On earnings-per-share growth, the picture is similar: Abbott Laboratories grew EPS 133. 6% year-over-year, compared to -18. 4% for Glaukos Corporation. Over a 3-year CAGR, IRTC leads at 22. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — GKOS or ATRC or NVCR or IRTC or ABT?

Abbott Laboratories (ABT) is the more profitable company, earning 31.

9% net margin versus -37. 0% for Glaukos Corporation — meaning it keeps 31. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABT leads at 16. 3% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — GKOS leads at 77. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is GKOS or ATRC or NVCR or IRTC or ABT more undervalued right now?

On forward earnings alone, Abbott Laboratories (ABT) trades at 15.

4x forward P/E versus 27422. 7x for iRhythm Technologies, Inc. — 27407. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ATRC: 95. 3% to $51. 33.

08

Which pays a better dividend — GKOS or ATRC or NVCR or IRTC or ABT?

In this comparison, ABT (2.

6% yield) pays a dividend. GKOS, ATRC, NVCR, IRTC do not pay a meaningful dividend and should not be held primarily for income.

09

Is GKOS or ATRC or NVCR or IRTC or ABT better for a retirement portfolio?

For long-horizon retirement investors, Abbott Laboratories (ABT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

22), 2. 6% yield, +166. 6% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABT: +166. 6%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between GKOS and ATRC and NVCR and IRTC and ABT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: GKOS is a small-cap high-growth stock; ATRC is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; IRTC is a small-cap high-growth stock; ABT is a mid-cap deep-value stock. ABT pays a dividend while GKOS, ATRC, NVCR, IRTC do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Revenue Growth>
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(GKOS: 41.2% · ATRC: 14.3%)

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