Biotechnology
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5 / 10Stock Comparison
IBRX vs FATE vs NKTR vs IMVT vs KYMR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
IBRX vs FATE vs NKTR vs IMVT vs KYMR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $7.64B | $280M | $1.69B | $5.53B | $6.91B |
| Revenue (TTM) | $83M | $7M | $55M | $0.00 | $51M |
| Net Income (TTM) | $-349M | $-136M | $-164M | $-464M | $-315M |
| Gross Margin | 94.8% | — | 99.6% | — | 33.2% |
| Operating Margin | -315.8% | -22.2% | -237.9% | — | -7.0% |
| Total Debt | $504M | $78M | $149M | $98K | $82M |
| Cash & Equiv. | $143M | $47M | $15M | $714M | $357M |
IBRX vs FATE vs NKTR vs IMVT vs KYMR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Aug 20 | May 26 | Return |
|---|---|---|---|
| ImmunityBio, Inc. (IBRX) | 100 | 106.3 | +6.3% |
| Fate Therapeutics, … (FATE) | 100 | 6.7 | -93.3% |
| Nektar Therapeutics (NKTR) | 100 | 28.7 | -71.3% |
| Immunovant, Inc. (IMVT) | 100 | 80.2 | -19.8% |
| Kymera Therapeutics… (KYMR) | 100 | 265.3 | +165.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IBRX vs FATE vs NKTR vs IMVT vs KYMR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IBRX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 22.7%, EPS growth 46.1%, 3Y rev CAGR 150.9%
- 22.7% revenue growth vs FATE's -51.2%
Among these 5 stocks, FATE doesn't own a clear edge in any measured category.
NKTR ranks third and is worth considering specifically for momentum.
- +8.2% vs IMVT's +96.1%
IMVT is the clearest fit if your priority is long-term compounding and sleep-well-at-night.
- 173.6% 10Y total return vs KYMR's 154.4%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- 3.2% margin vs FATE's -20.5%
KYMR carries the broadest edge in this set and is the clearest fit for income & stability and defensive.
- beta 1.15
- Beta 1.15, current ratio 10.47x
- Beta 1.15 vs IBRX's 2.21
- -22.3% ROA vs IBRX's -93.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 22.7% revenue growth vs FATE's -51.2% | |
| Quality / Margins | 3.2% margin vs FATE's -20.5% | |
| Stability / Safety | Beta 1.15 vs IBRX's 2.21 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +8.2% vs IMVT's +96.1% | |
| Efficiency (ROA) | -22.3% ROA vs IBRX's -93.2% |
IBRX vs FATE vs NKTR vs IMVT vs KYMR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
IBRX vs FATE vs NKTR vs IMVT vs KYMR — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NKTR leads in 2 of 6 categories
KYMR leads 1 • IBRX leads 0 • FATE leads 0 • IMVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NKTR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IBRX and IMVT operate at a comparable scale, with $83M and $0 in trailing revenue. NKTR is the more profitable business, keeping -3.0% of every revenue dollar as net income compared to FATE's -20.5%. On growth, IBRX holds the edge at +4.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $83M | $7M | $55M | $0 | $51M |
| EBITDAEarnings before interest/tax | -$245M | -$148M | -$130M | -$487M | -$352M |
| Net IncomeAfter-tax profit | -$349M | -$136M | -$164M | -$464M | -$315M |
| Free Cash FlowCash after capex | -$324M | -$88M | -$209M | -$423M | -$244M |
| Gross MarginGross profit ÷ Revenue | +94.8% | — | +99.6% | — | +33.2% |
| Operating MarginEBIT ÷ Revenue | -3.2% | -22.2% | -2.4% | — | -7.0% |
| Net MarginNet income ÷ Revenue | -4.2% | -20.5% | -3.0% | — | -6.1% |
| FCF MarginFCF ÷ Revenue | -3.9% | -13.2% | -3.8% | — | -4.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | +4.3% | -26.4% | -25.3% | — | +55.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +40.8% | +38.6% | -4.5% | +19.7% | +13.4% |
Valuation Metrics
Evenly matched — FATE and NKTR and KYMR each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $7.6B | $280M | $1.7B | $5.5B | $6.9B |
| Enterprise ValueMkt cap + debt − cash | $8.0B | $312M | $1.8B | $4.8B | $6.6B |
| Trailing P/EPrice ÷ TTM EPS | -12.52x | -2.11x | -8.57x | -9.97x | -22.93x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 518.37x | 42.18x | 30.64x | — | 176.26x |
| Price / BookPrice ÷ Book value/share | — | 1.39x | 15.66x | 5.83x | 4.52x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
KYMR leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-4 for NKTR. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), IBRX scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -65.8% | -4.0% | -47.1% | -25.0% |
| ROA (TTM)Return on assets | -93.2% | -42.7% | -62.8% | -44.1% | -22.3% |
| ROICReturn on invested capital | — | -36.5% | -57.2% | — | -24.9% |
| ROCEReturn on capital employed | -88.9% | -43.1% | -55.7% | -66.1% | -27.2% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 2 | 2 | 4 |
| Debt / EquityFinancial leverage | — | 0.38x | 1.66x | 0.00x | 0.05x |
| Net DebtTotal debt minus cash | $361M | $31M | $134M | -$714M | -$275M |
| Cash & Equiv.Liquid assets | $143M | $47M | $15M | $714M | $357M |
| Total DebtShort + long-term debt | $504M | $78M | $149M | $98,000 | $82M |
| Interest CoverageEBIT ÷ Interest expense | -2.48x | — | -4.74x | — | -2119.53x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $318 for FATE. Over the past 12 months, NKTR leads with a +818.2% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs FATE's -23.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +284.2% | +145.5% | +92.0% | +5.1% | +16.3% |
| 1-Year ReturnPast 12 months | +310.6% | +143.0% | +818.2% | +96.1% | +190.7% |
| 3-Year ReturnCumulative with dividends | +21.1% | -55.4% | +621.8% | +40.9% | +205.1% |
| 5-Year ReturnCumulative with dividends | -53.6% | -96.8% | -72.3% | +62.4% | +92.1% |
| 10-Year ReturnCumulative with dividends | -7.5% | +40.5% | -59.1% | +173.6% | +154.4% |
| CAGR (3Y)Annualised 3-year return | +6.6% | -23.6% | +93.3% | +12.1% | +45.0% |
Risk & Volatility
Evenly matched — FATE and KYMR each lead in 1 of 2 comparable metrics.
Risk & Volatility
KYMR is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than IBRX's 2.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FATE currently trades 98.6% from its 52-week high vs IBRX's 62.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.21x | 2.17x | 1.85x | 1.37x | 1.15x |
| 52-Week HighHighest price in past year | $12.43 | $2.46 | $109.00 | $30.09 | $103.00 |
| 52-Week LowLowest price in past year | $1.83 | $0.91 | $7.99 | $13.36 | $28.06 |
| % of 52W HighCurrent price vs 52-week peak | +62.4% | +98.6% | +76.5% | +90.5% | +82.2% |
| RSI (14)Momentum oscillator 0–100 | 59.4 | 81.0 | 53.4 | 60.2 | 54.1 |
| Avg Volume (50D)Average daily shares traded | 20.4M | 1.9M | 991K | 1.4M | 602K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: IBRX as "Buy", FATE as "Buy", NKTR as "Buy", IMVT as "Buy", KYMR as "Buy". Consensus price targets imply 1525.5% upside for FATE (target: $40) vs 38.3% for KYMR (target: $117).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $13.50 | $39.50 | $132.83 | $45.50 | $117.06 |
| # AnalystsCovering analysts | 5 | 31 | 33 | 23 | 26 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
NKTR leads in 2 of 6 categories (Income & Cash Flow, Total Returns). KYMR leads in 1 (Profitability & Efficiency). 2 tied.
IBRX vs FATE vs NKTR vs IMVT vs KYMR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is IBRX or FATE or NKTR or IMVT or KYMR a better buy right now?
For growth investors, ImmunityBio, Inc.
(IBRX) is the stronger pick with 22. 7% revenue growth year-over-year, versus -51. 2% for Fate Therapeutics, Inc. (FATE). Analysts rate ImmunityBio, Inc. (IBRX) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — IBRX or FATE or NKTR or IMVT or KYMR?
Over the past 5 years, Kymera Therapeutics, Inc.
(KYMR) delivered a total return of +92. 1%, compared to -96. 8% for Fate Therapeutics, Inc. (FATE). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus NKTR's -59. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — IBRX or FATE or NKTR or IMVT or KYMR?
By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.
(KYMR) is the lower-risk stock at 1. 15β versus ImmunityBio, Inc. 's 2. 21β — meaning IBRX is approximately 93% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — IBRX or FATE or NKTR or IMVT or KYMR?
By revenue growth (latest reported year), ImmunityBio, Inc.
(IBRX) is pulling ahead at 22. 7% versus -51. 2% for Fate Therapeutics, Inc. (FATE). On earnings-per-share growth, the picture is similar: ImmunityBio, Inc. grew EPS 46. 1% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, IBRX leads at 150. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — IBRX or FATE or NKTR or IMVT or KYMR?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -28. 0% for ImmunityBio, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -23. 3% for IBRX. At the gross margin level — before operating expenses — IBRX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — IBRX or FATE or NKTR or IMVT or KYMR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is IBRX or FATE or NKTR or IMVT or KYMR better for a retirement portfolio?
For long-horizon retirement investors, Kymera Therapeutics, Inc.
(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), +154. 4% 10Y return). ImmunityBio, Inc. (IBRX) carries a higher beta of 2. 21 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +154. 4%, IBRX: -7. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between IBRX and FATE and NKTR and IMVT and KYMR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: IBRX is a small-cap high-growth stock; FATE is a small-cap quality compounder stock; NKTR is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; KYMR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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