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INVA vs DBVT vs PRGO vs AZN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - General
INVA vs DBVT vs PRGO vs AZN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - General |
| Market Cap | $1.93B | $1712.35T | $1.61B | $282.96B |
| Revenue (TTM) | $424M | $0.00 | $4.18B | $60.44B |
| Net Income (TTM) | $504M | $-168M | $-1.82B | $10.39B |
| Gross Margin | 76.2% | — | 34.2% | 81.7% |
| Operating Margin | 14.8% | — | -4.1% | 23.7% |
| Forward P/E | 11.9x | — | 5.6x | 17.7x |
| Total Debt | $269M | $22M | $3.97B | $29.70B |
| Cash & Equiv. | $551M | $194M | $532M | $5.71B |
INVA vs DBVT vs PRGO vs AZN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Innoviva, Inc. (INVA) | 100 | 163.2 | +63.2% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Perrigo Company plc (PRGO) | 100 | 21.4 | -78.6% |
| AstraZeneca PLC (AZN) | 100 | 170.2 | +70.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: INVA vs DBVT vs PRGO vs AZN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.
- Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
- Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
- Beta 0.13, current ratio 14.64x
- 18.5% revenue growth vs DBVT's -100.0%
DBVT is the clearest fit if your priority is momentum.
- +110.4% vs PRGO's -51.2%
PRGO is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 10 yrs, beta 1.18, yield 9.8%
- Better valuation composite
- 9.8% yield, 10-year raise streak, vs AZN's 1.8%, (2 stocks pay no dividend)
AZN is the clearest fit if your priority is long-term compounding and valuation efficiency.
- 268.6% 10Y total return vs INVA's 94.9%
- PEG 0.81 vs INVA's 1.15
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 18.5% revenue growth vs DBVT's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 118.9% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.13 vs DBVT's 1.26 | |
| Dividends | 9.8% yield, 10-year raise streak, vs AZN's 1.8%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +110.4% vs PRGO's -51.2% | |
| Efficiency (ROA) | 32.4% ROA vs DBVT's -89.0% |
INVA vs DBVT vs PRGO vs AZN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
INVA vs DBVT vs PRGO vs AZN — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INVA leads in 3 of 6 categories
PRGO leads 2 • DBVT leads 0 • AZN leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — INVA and AZN each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
AZN and DBVT operate at a comparable scale, with $60.4B and $0 in trailing revenue. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, AZN holds the edge at +12.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $424M | $0 | $4.2B | $60.4B |
| EBITDAEarnings before interest/tax | $86M | -$112M | $58M | $20.1B |
| Net IncomeAfter-tax profit | $504M | -$168M | -$1.8B | $10.4B |
| Free Cash FlowCash after capex | $181M | -$151M | $108M | $9.1B |
| Gross MarginGross profit ÷ Revenue | +76.2% | — | +34.2% | +81.7% |
| Operating MarginEBIT ÷ Revenue | +14.8% | — | -4.1% | +23.7% |
| Net MarginNet income ÷ Revenue | +118.9% | — | -43.5% | +17.2% |
| FCF MarginFCF ÷ Revenue | +42.8% | — | +2.6% | +15.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +10.6% | — | -7.2% | +12.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +4.0% | +91.5% | -56.4% | +5.3% |
Valuation Metrics
PRGO leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 75% valuation discount to AZN's 27.9x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs AZN's 1.28x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.9B | $1712.35T | $1.6B | $283.0B |
| Enterprise ValueMkt cap + debt − cash | $1.7B | $1712.35T | $5.1B | $306.9B |
| Trailing P/EPrice ÷ TTM EPS | 6.91x | -0.76x | -1.14x | 27.91x |
| Forward P/EPrice ÷ next-FY EPS est. | 11.91x | — | 5.56x | 17.74x |
| PEG RatioP/E ÷ EPS growth rate | 0.67x | — | — | 1.28x |
| EV / EBITDAEnterprise value multiple | 8.10x | — | 7.42x | 15.76x |
| Price / SalesMarket cap ÷ Revenue | 4.55x | — | 0.38x | 4.82x |
| Price / BookPrice ÷ Book value/share | 1.65x | 0.66x | 0.55x | 5.85x |
| Price / FCFMarket cap ÷ FCF | 9.88x | — | 11.12x | 24.05x |
Profitability & Efficiency
INVA leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), AZN scores 8/9 vs PRGO's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +46.5% | -130.2% | -50.7% | +22.2% |
| ROA (TTM)Return on assets | +32.4% | -89.0% | -19.8% | +9.1% |
| ROICReturn on invested capital | +14.2% | — | +3.7% | +14.9% |
| ROCEReturn on capital employed | +12.4% | -145.7% | +4.3% | +17.2% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 4 | 8 |
| Debt / EquityFinancial leverage | 0.23x | 0.13x | 1.35x | 0.61x |
| Net DebtTotal debt minus cash | -$282M | -$172M | $3.4B | $24.0B |
| Cash & Equiv.Liquid assets | $551M | $194M | $532M | $5.7B |
| Total DebtShort + long-term debt | $269M | $22M | $4.0B | $29.7B |
| Interest CoverageEBIT ÷ Interest expense | 63.45x | -189.82x | -7.20x | 8.43x |
Total Returns (Dividends Reinvested)
INVA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs PRGO's -25.2% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +14.7% | +4.9% | -13.5% | +1.1% |
| 1-Year ReturnPast 12 months | +21.7% | +110.4% | -51.2% | +33.9% |
| 3-Year ReturnCumulative with dividends | +95.2% | +19.7% | -58.1% | +30.4% |
| 5-Year ReturnCumulative with dividends | +94.4% | -69.1% | -60.1% | +82.2% |
| 10-Year ReturnCumulative with dividends | +94.9% | -87.0% | -77.7% | +268.6% |
| CAGR (3Y)Annualised 3-year return | +25.0% | +6.2% | -25.2% | +9.3% |
Risk & Volatility
INVA leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 90.7% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.13x | 1.26x | 1.18x | 0.67x |
| 52-Week HighHighest price in past year | $25.15 | $26.18 | $28.44 | $212.71 |
| 52-Week LowLowest price in past year | $16.52 | $7.53 | $9.23 | $91.44 |
| % of 52W HighCurrent price vs 52-week peak | +90.7% | +76.3% | +41.2% | +85.8% |
| RSI (14)Momentum oscillator 0–100 | 39.9 | 48.1 | 60.9 | 39.1 |
| Avg Volume (50D)Average daily shares traded | 621K | 252K | 3.4M | 1.9M |
Analyst Outlook
PRGO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: INVA as "Buy", DBVT as "Buy", PRGO as "Hold", AZN as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 15.6% for AZN (target: $211). For income investors, PRGO offers the higher dividend yield at 9.81% vs AZN's 1.78%.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $37.67 | $46.33 | $20.00 | $211.00 |
| # AnalystsCovering analysts | 10 | 15 | 36 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | +9.8% | +1.8% |
| Dividend StreakConsecutive years of raises | 0 | 0 | 10 | 4 |
| Dividend / ShareAnnual DPS | — | — | $1.15 | $3.25 |
| Buyback YieldShare repurchases ÷ mkt cap | +0.2% | 0.0% | 0.0% | +0.3% |
INVA leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). PRGO leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.
INVA vs DBVT vs PRGO vs AZN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is INVA or DBVT or PRGO or AZN a better buy right now?
For growth investors, Innoviva, Inc.
(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate Innoviva, Inc. (INVA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — INVA or DBVT or PRGO or AZN?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus AstraZeneca PLC at 27. 9x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: AstraZeneca PLC wins at 0. 81x versus Innoviva, Inc. 's 1. 15x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — INVA or DBVT or PRGO or AZN?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 4%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: AZN returned +268. 6% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — INVA or DBVT or PRGO or AZN?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 897% more volatile than INVA relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
05Which is growing faster — INVA or DBVT or PRGO or AZN?
By revenue growth (latest reported year), Innoviva, Inc.
(INVA) is pulling ahead at 18. 5% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, AZN leads at 9. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — INVA or DBVT or PRGO or AZN?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — AZN leads at 81. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is INVA or DBVT or PRGO or AZN more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, AstraZeneca PLC (AZN) is the more undervalued stock at a PEG of 0. 81x versus Innoviva, Inc. 's 1. 15x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 6x forward P/E versus 17. 7x for AstraZeneca PLC — 12. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — INVA or DBVT or PRGO or AZN?
In this comparison, PRGO (9.
8% yield), AZN (1. 8% yield) pay a dividend. INVA, DBVT do not pay a meaningful dividend and should not be held primarily for income.
09Is INVA or DBVT or PRGO or AZN better for a retirement portfolio?
For long-horizon retirement investors, AstraZeneca PLC (AZN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
67), 1. 8% yield, +268. 6% 10Y return). Both have compounded well over 10 years (AZN: +268. 6%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between INVA and DBVT and PRGO and AZN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: INVA is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; PRGO is a small-cap income-oriented stock; AZN is a large-cap quality compounder stock. PRGO, AZN pay a dividend while INVA, DBVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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