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IVA logo
IVA
AKBA logo
AKBA
KO logo
KO
FOLD logo
FOLD
HALO logo
HALO
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Stock Comparison

IVA vs AKBA vs KO vs FOLD vs HALO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IVA
Inventiva S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$200M
5Y Perf.-62.2%
AKBA
Akebia Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$248M
5Y Perf.-91.7%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+74.9%
FOLD
Amicus Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$4.55B
5Y Perf.+0.1%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$8.24B
5Y Perf.+155.6%

IVA vs AKBA vs KO vs FOLD vs HALO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IVA logoIVA
AKBA logoAKBA
KO logoKO
FOLD logoFOLD
HALO logoHALO
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicBiotechnologyBiotechnology
Market Cap$200M$248M$355.61B$4.55B$8.24B
Revenue (TTM)$30M$232M$49.28B$634M$1.51B
Net Income (TTM)$-415M$-21M$13.70B$-27M$349M
Gross Margin92.5%80.9%61.7%87.9%76.9%
Operating Margin-6.7%2.3%29.3%5.2%57.0%
Forward P/E25.3x40.6x8.6x
Total Debt$54M$216M$45.49B$483M$2.14B
Cash & Equiv.$97M$185M$10.27B$214M$134M

IVA vs AKBA vs KO vs FOLD vs HALOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IVA
AKBA
KO
FOLD
HALO
StockJul 20Jun 26Return
Inventiva S.A. (IVA)10037.8-62.2%
Akebia Therapeutics… (AKBA)1008.3-91.7%
The Coca-Cola Compa… (KO)100174.9+74.9%
Amicus Therapeutics… (FOLD)100100.1+0.1%
Halozyme Therapeuti… (HALO)100255.6+155.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: IVA vs AKBA vs KO vs FOLD vs HALO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO and FOLD are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Amicus Therapeutics, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. HALO and AKBA also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
IVA
Inventiva S.A.
The Healthcare Pick

Among these 5 stocks, IVA doesn't own a clear edge in any measured category.

Best for: healthcare exposure
AKBA
Akebia Therapeutics, Inc.
The Growth Play

AKBA is the clearest fit if your priority is growth exposure.

  • Rev growth 47.5%, EPS growth 93.7%, 3Y rev CAGR -6.9%
  • 47.5% revenue growth vs IVA's -47.4%
Best for: growth exposure
KO
The Coca-Cola Company
The Quality Compounder

KO has the current edge in this matchup, primarily because of its strength in quality and dividends.

  • 27.8% margin vs IVA's -13.8%
  • 2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Best for: quality and dividends
FOLD
Amicus Therapeutics, Inc.
The Income Pick

FOLD is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 0.48
  • Lower volatility, beta 0.48, current ratio 2.84x
  • Beta 0.48, current ratio 2.84x
  • Beta 0.48 vs IVA's 1.59
Best for: income & stability and sleep-well-at-night
HALO
Halozyme Therapeutics, Inc.
The Long-Run Compounder

HALO ranks third and is worth considering specifically for long-term compounding and valuation efficiency.

  • 7.0% 10Y total return vs KO's 121.1%
  • PEG 0.37 vs KO's 2.26
  • Lower P/E (8.6x vs 40.6x)
  • 14.7% ROA vs IVA's -232.6%
Best for: long-term compounding and valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthAKBA logoAKBA47.5% revenue growth vs IVA's -47.4%
ValueHALO logoHALOLower P/E (8.6x vs 40.6x)
Quality / MarginsKO logoKO27.8% margin vs IVA's -13.8%
Stability / SafetyFOLD logoFOLDBeta 0.48 vs IVA's 1.59
DividendsKO logoKO2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)FOLD logoFOLD+134.8% vs AKBA's -74.7%
Efficiency (ROA)HALO logoHALO14.7% ROA vs IVA's -232.6%

IVA vs AKBA vs KO vs FOLD vs HALO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IVAInventiva S.A.

Segment breakdown not available.

AKBAAkebia Therapeutics, Inc.
FY 2025
License Collaboration And Other Revenue
95.7%$9M
Supply Agreement
3.2%$300,000
License Collaboration And Other Revenue, Royalties
1.1%$100,000
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
FOLDAmicus Therapeutics, Inc.

Segment breakdown not available.

HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M

IVA vs AKBA vs KO vs FOLD vs HALO — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHALOLAGGINGFOLD

Income & Cash Flow (Last 12 Months)

HALO leads this category, winning 3 of 6 comparable metrics.

KO is the larger business by revenue, generating $49.3B annually — 1632.3x IVA's $30M. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to IVA's -13.8%. On growth, IVA holds the edge at +62.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIVA logoIVAInventiva S.A.AKBA logoAKBAAkebia Therapeuti…KO logoKOThe Coca-Cola Com…FOLD logoFOLDAmicus Therapeuti…HALO logoHALOHalozyme Therapeu…
RevenueTrailing 12 months$30M$232M$49.3B$634M$1.5B
EBITDAEarnings before interest/tax-$195M$7M$15.5B$40M$961M
Net IncomeAfter-tax profit-$415M-$21M$13.7B-$27M$349M
Free Cash FlowCash after capex-$177M$60M$12.6B$30M$668M
Gross MarginGross profit ÷ Revenue+92.5%+80.9%+61.7%+87.9%+76.9%
Operating MarginEBIT ÷ Revenue-6.7%+2.3%+29.3%+5.2%+57.0%
Net MarginNet income ÷ Revenue-13.8%-8.8%+27.8%-4.3%+23.1%
FCF MarginFCF ÷ Revenue-5.9%+25.8%+25.5%+4.7%+44.3%
Rev. Growth (YoY)Latest quarter vs prior year+62.9%-6.6%+12.1%+23.7%+42.2%
EPS Growth (YoY)Latest quarter vs prior year-72.3%-2.3%+18.2%-89.0%+31.2%
HALO leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

AKBA leads this category, winning 4 of 7 comparable metrics.

At 27.1x trailing earnings, HALO trades at a 0% valuation discount to KO's 27.2x P/E. Adjusting for growth (PEG ratio), HALO offers better value at 1.18x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricIVA logoIVAInventiva S.A.AKBA logoAKBAAkebia Therapeuti…KO logoKOThe Coca-Cola Com…FOLD logoFOLDAmicus Therapeuti…HALO logoHALOHalozyme Therapeu…
Market CapShares × price$200M$248M$355.6B$4.5B$8.2B
Enterprise ValueMkt cap + debt − cash$151M$279M$390.8B$4.8B$10.3B
Trailing P/EPrice ÷ TTM EPS-0.94x-44.45x27.18x-164.85x27.15x
Forward P/EPrice ÷ next-FY EPS est.25.27x40.62x8.57x
PEG RatioP/E ÷ EPS growth rate2.43x1.18x
EV / EBITDAEnterprise value multiple11.28x26.39x114.88x11.34x
Price / SalesMarket cap ÷ Revenue18.82x1.05x7.42x7.17x5.90x
Price / BookPrice ÷ Book value/share7.29x10.40x16.29x176.41x
Price / FCFMarket cap ÷ FCF3.65x67.15x152.43x12.79x
AKBA leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

HALO leads this category, winning 5 of 9 comparable metrics.

HALO delivers a 126.3% return on equity — every $100 of shareholder capital generates $126 in annual profit, vs $-63 for AKBA. KO carries lower financial leverage with a 1.33x debt-to-equity ratio, signaling a more conservative balance sheet compared to HALO's 43.89x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs IVA's 2/9, reflecting strong financial health.

MetricIVA logoIVAInventiva S.A.AKBA logoAKBAAkebia Therapeuti…KO logoKOThe Coca-Cola Com…FOLD logoFOLDAmicus Therapeuti…HALO logoHALOHalozyme Therapeu…
ROE (TTM)Return on equity-62.7%+41.1%-12.0%+126.3%
ROA (TTM)Return on assets-2.3%-5.7%+13.1%-3.2%+14.7%
ROICReturn on invested capital+23.2%+15.8%+5.3%+32.1%
ROCEReturn on capital employed-11.1%+13.3%+17.3%+5.1%+38.2%
Piotroski ScoreFundamental quality 0–925745
Debt / EquityFinancial leverage6.63x1.33x1.76x43.89x
Net DebtTotal debt minus cash-$42M$31M$35.2B$269M$2.0B
Cash & Equiv.Liquid assets$97M$185M$10.3B$214M$134M
Total DebtShort + long-term debt$54M$216M$45.5B$483M$2.1B
Interest CoverageEBIT ÷ Interest expense-15.39x0.16x10.70x1.00x44.97x
HALO leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

HALO leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in KO five years ago would be worth $16,560 today (with dividends reinvested), compared to $2,477 for IVA. Over the past 12 months, FOLD leads with a +134.8% total return vs AKBA's -74.7%. The 3-year compound annual growth rate (CAGR) favors HALO at 27.3% vs AKBA's -9.8% — a key indicator of consistent wealth creation.

MetricIVA logoIVAInventiva S.A.AKBA logoAKBAAkebia Therapeuti…KO logoKOThe Coca-Cola Com…FOLD logoFOLDAmicus Therapeuti…HALO logoHALOHalozyme Therapeu…
YTD ReturnYear-to-date-19.1%-40.4%+20.3%+1.5%-1.2%
1-Year ReturnPast 12 months+13.6%-74.7%+17.2%+134.8%+27.4%
3-Year ReturnCumulative with dividends+9.7%-26.6%+47.0%+11.6%+106.4%
5-Year ReturnCumulative with dividends-75.2%-74.7%+65.6%+35.2%+60.3%
10-Year ReturnCumulative with dividends-71.3%-89.0%+121.1%+147.3%+701.6%
CAGR (3Y)Annualised 3-year return+3.1%-9.8%+13.7%+3.7%+27.3%
HALO leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — KO and FOLD each lead in 1 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than IVA's 1.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FOLD currently trades 99.9% from its 52-week high vs AKBA's 22.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIVA logoIVAInventiva S.A.AKBA logoAKBAAkebia Therapeuti…KO logoKOThe Coca-Cola Com…FOLD logoFOLDAmicus Therapeuti…HALO logoHALOHalozyme Therapeu…
Beta (5Y)Sensitivity to S&P 5001.59x1.32x-0.20x0.48x0.58x
52-Week HighHighest price in past year$7.98$4.08$84.04$14.50$82.22
52-Week LowLowest price in past year$2.85$0.82$65.35$5.51$51.06
% of 52W HighCurrent price vs 52-week peak+48.2%+22.7%+98.3%+99.9%+84.5%
RSI (14)Momentum oscillator 0–10028.432.960.672.257.1
Avg Volume (50D)Average daily shares traded478K4.1M12.7M2.3M1.5M
Evenly matched — KO and FOLD each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: IVA as "Buy", AKBA as "Buy", KO as "Buy", FOLD as "Buy", HALO as "Buy". Consensus price targets imply 332.7% upside for AKBA (target: $4) vs 0.1% for FOLD (target: $15). KO is the only dividend payer here at 2.46% yield — a key consideration for income-focused portfolios.

MetricIVA logoIVAInventiva S.A.AKBA logoAKBAAkebia Therapeuti…KO logoKOThe Coca-Cola Com…FOLD logoFOLDAmicus Therapeuti…HALO logoHALOHalozyme Therapeu…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$16.50$4.00$86.13$14.50$88.25
# AnalystsCovering analysts811482427
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises56
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.2%0.0%+4.2%
Insufficient data to determine a leader in this category.
Key Takeaway

HALO leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). AKBA leads in 1 (Valuation Metrics). 1 tied.

Best OverallHalozyme Therapeutics, Inc. (HALO)Leads 3 of 6 categories
Loading custom metrics...

IVA vs AKBA vs KO vs FOLD vs HALO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is IVA or AKBA or KO or FOLD or HALO a better buy right now?

For growth investors, Akebia Therapeutics, Inc.

(AKBA) is the stronger pick with 47. 5% revenue growth year-over-year, versus -47. 4% for Inventiva S. A. (IVA). Halozyme Therapeutics, Inc. (HALO) offers the better valuation at 27. 1x trailing P/E (8. 6x forward), making it the more compelling value choice. Analysts rate Inventiva S. A. (IVA) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — IVA or AKBA or KO or FOLD or HALO?

On trailing P/E, Halozyme Therapeutics, Inc.

(HALO) is the cheapest at 27. 1x versus The Coca-Cola Company at 27. 2x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 6x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 37x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — IVA or AKBA or KO or FOLD or HALO?

Over the past 5 years, The Coca-Cola Company (KO) delivered a total return of +65.

6%, compared to -75. 2% for Inventiva S. A. (IVA). Over 10 years, the gap is even starker: HALO returned +701. 6% versus AKBA's -89. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — IVA or AKBA or KO or FOLD or HALO?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Inventiva S. A. 's 1. 59β — meaning IVA is approximately -893% more volatile than KO relative to the S&P 500. On balance sheet safety, The Coca-Cola Company (KO) carries a lower debt/equity ratio of 133% versus 44% for Halozyme Therapeutics, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — IVA or AKBA or KO or FOLD or HALO?

By revenue growth (latest reported year), Akebia Therapeutics, Inc.

(AKBA) is pulling ahead at 47. 5% versus -47. 4% for Inventiva S. A. (IVA). On earnings-per-share growth, the picture is similar: Akebia Therapeutics, Inc. grew EPS 93. 7% year-over-year, compared to -45. 7% for Inventiva S. A.. Over a 3-year CAGR, IVA leads at 29. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — IVA or AKBA or KO or FOLD or HALO?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -20. 0% for Inventiva S. A. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -1060. 6% for IVA. At the gross margin level — before operating expenses — IVA leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is IVA or AKBA or KO or FOLD or HALO more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 37x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 6x forward P/E versus 40. 6x for Amicus Therapeutics, Inc. — 32. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AKBA: 332. 7% to $4. 00.

08

Which pays a better dividend — IVA or AKBA or KO or FOLD or HALO?

In this comparison, KO (2.

5% yield) pays a dividend. IVA, AKBA, FOLD, HALO do not pay a meaningful dividend and should not be held primarily for income.

09

Is IVA or AKBA or KO or FOLD or HALO better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Inventiva S. A. (IVA) carries a higher beta of 1. 59 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, IVA: -71. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between IVA and AKBA and KO and FOLD and HALO?

These companies operate in different sectors (IVA (Healthcare) and AKBA (Healthcare) and KO (Consumer Defensive) and FOLD (Healthcare) and HALO (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: IVA is a small-cap quality compounder stock; AKBA is a small-cap high-growth stock; KO is a large-cap quality compounder stock; FOLD is a small-cap high-growth stock; HALO is a small-cap high-growth stock. KO pays a dividend while IVA, AKBA, FOLD, HALO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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