Biotechnology
Build Your Comparison
Side-by-side financial analysisStock Comparison
IVA vs MDGL vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Beverages - Non-Alcoholic
IVA vs MDGL vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Beverages - Non-Alcoholic |
| Market Cap | $200M | $11.08B | $355.61B |
| Revenue (TTM) | $30M | $1.13B | $49.28B |
| Net Income (TTM) | $-415M | $-309M | $13.70B |
| Gross Margin | 92.5% | 93.1% | 61.7% |
| Operating Margin | -6.7% | -27.7% | 29.3% |
| Forward P/E | — | — | 25.3x |
| Total Debt | $54M | $354M | $45.49B |
| Cash & Equiv. | $97M | $199M | $10.27B |
IVA vs MDGL vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 20 | Jun 26 | Return |
|---|---|---|---|
| Inventiva S.A. (IVA) | 100 | 37.8 | -62.2% |
| Madrigal Pharmaceut… (MDGL) | 100 | 468.5 | +368.5% |
| The Coca-Cola Compa… (KO) | 100 | 174.9 | +74.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IVA vs MDGL vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IVA plays a supporting role in this comparison — it may shine differently against other peers.
MDGL carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 1 yrs, beta 0.49
- Rev growth 432.1%, EPS growth 41.3%
- 39.4% 10Y total return vs KO's 121.1%
KO is the clearest fit if your priority is quality and dividends.
- 27.8% margin vs IVA's -13.8%
- 2.5% yield; 56-year raise streak; the other 2 pay no meaningful dividend
- 13.1% ROA vs IVA's -232.6%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 432.1% revenue growth vs IVA's -47.4% | |
| Quality / Margins | 27.8% margin vs IVA's -13.8% | |
| Stability / Safety | Beta 0.49 vs IVA's 1.59 | |
| Dividends | 2.5% yield; 56-year raise streak; the other 2 pay no meaningful dividend | |
| Momentum (1Y) | +61.8% vs IVA's +13.6% | |
| Efficiency (ROA) | 13.1% ROA vs IVA's -232.6% |
IVA vs MDGL vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
IVA vs MDGL vs KO — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
KO leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
KO is the larger business by revenue, generating $49.3B annually — 1632.3x IVA's $30M. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to IVA's -13.8%. On growth, MDGL holds the edge at +126.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $30M | $1.1B | $49.3B |
| EBITDAEarnings before interest/tax | -$195M | -$312M | $15.5B |
| Net IncomeAfter-tax profit | -$415M | -$309M | $13.7B |
| Free Cash FlowCash after capex | -$177M | -$272M | $12.6B |
| Gross MarginGross profit ÷ Revenue | +92.5% | +93.1% | +61.7% |
| Operating MarginEBIT ÷ Revenue | -6.7% | -27.7% | +29.3% |
| Net MarginNet income ÷ Revenue | -13.8% | -27.3% | +27.8% |
| FCF MarginFCF ÷ Revenue | -5.9% | -24.1% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | +62.9% | +126.8% | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | -72.3% | +2.1% | +18.2% |
Valuation Metrics
KO leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $200M | $11.1B | $355.6B |
| Enterprise ValueMkt cap + debt − cash | $151M | $11.2B | $390.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.94x | -37.41x | 27.18x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 25.27x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.43x |
| EV / EBITDAEnterprise value multiple | — | — | 26.39x |
| Price / SalesMarket cap ÷ Revenue | 18.82x | 11.57x | 7.42x |
| Price / BookPrice ÷ Book value/share | — | 17.90x | 10.40x |
| Price / FCFMarket cap ÷ FCF | — | — | 67.15x |
Profitability & Efficiency
KO leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-50 for MDGL. MDGL carries lower financial leverage with a 0.59x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs IVA's 2/9, reflecting strong financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | — | -50.2% | +41.1% |
| ROA (TTM)Return on assets | -2.3% | -25.4% | +13.1% |
| ROICReturn on invested capital | — | -29.4% | +15.8% |
| ROCEReturn on capital employed | -11.1% | -32.9% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 3 | 7 |
| Debt / EquityFinancial leverage | — | 0.59x | 1.33x |
| Net DebtTotal debt minus cash | -$42M | $156M | $35.2B |
| Cash & Equiv.Liquid assets | $97M | $199M | $10.3B |
| Total DebtShort + long-term debt | $54M | $354M | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | -15.39x | -25.80x | 10.70x |
Total Returns (Dividends Reinvested)
MDGL leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MDGL five years ago would be worth $44,660 today (with dividends reinvested), compared to $2,477 for IVA. Over the past 12 months, MDGL leads with a +61.8% total return vs IVA's +13.6%. The 3-year compound annual growth rate (CAGR) favors MDGL at 21.9% vs IVA's 3.1% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | -19.1% | -19.0% | +20.3% |
| 1-Year ReturnPast 12 months | +13.6% | +61.8% | +17.2% |
| 3-Year ReturnCumulative with dividends | +9.7% | +80.9% | +47.0% |
| 5-Year ReturnCumulative with dividends | -75.2% | +346.6% | +65.6% |
| 10-Year ReturnCumulative with dividends | -71.3% | +3940.1% | +121.1% |
| CAGR (3Y)Annualised 3-year return | +3.1% | +21.9% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than IVA's 1.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs IVA's 48.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.59x | 0.49x | -0.20x |
| 52-Week HighHighest price in past year | $7.98 | $615.00 | $84.04 |
| 52-Week LowLowest price in past year | $2.85 | $275.00 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +48.2% | +78.2% | +98.3% |
| RSI (14)Momentum oscillator 0–100 | 28.4 | 42.3 | 60.6 |
| Avg Volume (50D)Average daily shares traded | 478K | 263K | 12.7M |
Analyst Outlook
KO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: IVA as "Buy", MDGL as "Buy", KO as "Buy". Consensus price targets imply 328.6% upside for IVA (target: $17) vs 4.2% for KO (target: $86). KO is the only dividend payer here at 2.46% yield — a key consideration for income-focused portfolios.
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $16.50 | $710.22 | $86.13 |
| # AnalystsCovering analysts | 8 | 23 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | +2.5% |
| Dividend StreakConsecutive years of raises | — | 1 | 56 |
| Dividend / ShareAnnual DPS | — | — | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.2% |
KO leads in 5 of 6 categories (Income & Cash Flow, Valuation Metrics). MDGL leads in 1 (Total Returns).
IVA vs MDGL vs KO: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is IVA or MDGL or KO a better buy right now?
For growth investors, Madrigal Pharmaceuticals, Inc.
(MDGL) is the stronger pick with 432. 1% revenue growth year-over-year, versus -47. 4% for Inventiva S. A. (IVA). The Coca-Cola Company (KO) offers the better valuation at 27. 2x trailing P/E (25. 3x forward), making it the more compelling value choice. Analysts rate Inventiva S. A. (IVA) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — IVA or MDGL or KO?
Over the past 5 years, Madrigal Pharmaceuticals, Inc.
(MDGL) delivered a total return of +346. 6%, compared to -75. 2% for Inventiva S. A. (IVA). Over 10 years, the gap is even starker: MDGL returned +39. 4% versus IVA's -71. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — IVA or MDGL or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Inventiva S. A. 's 1. 59β — meaning IVA is approximately -893% more volatile than KO relative to the S&P 500. On balance sheet safety, Madrigal Pharmaceuticals, Inc. (MDGL) carries a lower debt/equity ratio of 59% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.
04Which is growing faster — IVA or MDGL or KO?
By revenue growth (latest reported year), Madrigal Pharmaceuticals, Inc.
(MDGL) is pulling ahead at 432. 1% versus -47. 4% for Inventiva S. A. (IVA). On earnings-per-share growth, the picture is similar: Madrigal Pharmaceuticals, Inc. grew EPS 41. 3% year-over-year, compared to -45. 7% for Inventiva S. A.. Over a 3-year CAGR, IVA leads at 29. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — IVA or MDGL or KO?
The Coca-Cola Company (KO) is the more profitable company, earning 27.
3% net margin versus -20. 0% for Inventiva S. A. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -1060. 6% for IVA. At the gross margin level — before operating expenses — IVA leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is IVA or MDGL or KO more undervalued right now?
Analyst consensus price targets imply the most upside for IVA: 328.
6% to $16. 50.
07Which pays a better dividend — IVA or MDGL or KO?
In this comparison, KO (2.
5% yield) pays a dividend. IVA, MDGL do not pay a meaningful dividend and should not be held primarily for income.
08Is IVA or MDGL or KO better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Inventiva S. A. (IVA) carries a higher beta of 1. 59 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, IVA: -71. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between IVA and MDGL and KO?
These companies operate in different sectors (IVA (Healthcare) and MDGL (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: IVA is a small-cap quality compounder stock; MDGL is a mid-cap high-growth stock; KO is a large-cap quality compounder stock. KO pays a dividend while IVA, MDGL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.