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Stock Comparison

JAZZ vs AVNS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
JAZZ
Jazz Pharmaceuticals plc

Biotechnology

HealthcareNASDAQ • IE
Market Cap$14.34B
5Y Perf.+91.6%
AVNS
Avanos Medical, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$1.15B
5Y Perf.-14.9%

JAZZ vs AVNS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
JAZZ logoJAZZ
AVNS logoAVNS
IndustryBiotechnologyMedical - Devices
Market Cap$14.34B$1.15B
Revenue (TTM)$4.44B$716M
Net Income (TTM)$29M$-69M
Gross Margin66.9%49.4%
Operating Margin13.9%-8.4%
Forward P/E9.5x24.7x
Total Debt$5.42B$129M
Cash & Equiv.$1.39B$90M

JAZZ vs AVNSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

JAZZ
AVNS
StockMay 20May 26Return
Jazz Pharmaceutical… (JAZZ)100191.6+91.6%
Avanos Medical, Inc. (AVNS)10085.1-14.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: JAZZ vs AVNS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JAZZ leads in 6 of 7 categories, making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
JAZZ
Jazz Pharmaceuticals plc
The Income Pick

JAZZ carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 0.65
  • Rev growth 4.9%, EPS growth -167.5%, 3Y rev CAGR 5.3%
  • 58.3% 10Y total return vs AVNS's -15.7%
Best for: income & stability and growth exposure
AVNS
Avanos Medical, Inc.
The Specific-Use Pick

In this particular matchup, AVNS is outpaced on most metrics by others in the set.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthJAZZ logoJAZZ4.9% revenue growth vs AVNS's 1.9%
ValueJAZZ logoJAZZLower P/E (9.5x vs 24.7x)
Quality / MarginsJAZZ logoJAZZ0.7% margin vs AVNS's -9.7%
Stability / SafetyJAZZ logoJAZZBeta 0.65 vs AVNS's 1.54
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)JAZZ logoJAZZ+105.6% vs AVNS's +92.4%
Efficiency (ROA)JAZZ logoJAZZ0.3% ROA vs AVNS's -6.6%, ROIC 2.1% vs -5.4%

JAZZ vs AVNS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

JAZZJazz Pharmaceuticals plc
FY 2025
Xywav
39.6%$1.7B
Epidiolex/Epidyolex
25.3%$1.1B
Rylaze/Enrylaze
9.6%$403M
Zepzelca
7.3%$307M
High Sodium AG Oxybate Product Royalty Revenue
5.1%$212M
Defitelio/Defibrotide
4.8%$199M
Vyxeos
3.5%$147M
Other (4)
4.8%$201M
AVNSAvanos Medical, Inc.
FY 2025
Corporate Other
100.0%$31M

JAZZ vs AVNS — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJAZZLAGGINGAVNS

Income & Cash Flow (Last 12 Months)

JAZZ leads this category, winning 6 of 6 comparable metrics.

JAZZ is the larger business by revenue, generating $4.4B annually — 6.2x AVNS's $716M. JAZZ is the more profitable business, keeping 0.7% of every revenue dollar as net income compared to AVNS's -9.7%. On growth, JAZZ holds the edge at +19.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricJAZZ logoJAZZJazz Pharmaceutic…AVNS logoAVNSAvanos Medical, I…
RevenueTrailing 12 months$4.4B$716M
EBITDAEarnings before interest/tax$994M-$21M
Net IncomeAfter-tax profit$29M-$69M
Free Cash FlowCash after capex$1.2B$24M
Gross MarginGross profit ÷ Revenue+66.9%+49.4%
Operating MarginEBIT ÷ Revenue+13.9%-8.4%
Net MarginNet income ÷ Revenue+0.7%-9.7%
FCF MarginFCF ÷ Revenue+28.1%+3.4%
Rev. Growth (YoY)Latest quarter vs prior year+19.1%+8.8%
EPS Growth (YoY)Latest quarter vs prior year+3.9%-21.4%
JAZZ leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

JAZZ leads this category, winning 3 of 5 comparable metrics.
MetricJAZZ logoJAZZJazz Pharmaceutic…AVNS logoAVNSAvanos Medical, I…
Market CapShares × price$14.3B$1.2B
Enterprise ValueMkt cap + debt − cash$18.4B$1.2B
Trailing P/EPrice ÷ TTM EPS-39.14x-16.93x
Forward P/EPrice ÷ next-FY EPS est.9.45x24.72x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple23.97x
Price / SalesMarket cap ÷ Revenue3.36x1.65x
Price / BookPrice ÷ Book value/share3.23x1.47x
Price / FCFMarket cap ÷ FCF11.06x26.77x
JAZZ leads this category, winning 3 of 5 comparable metrics.

Profitability & Efficiency

JAZZ leads this category, winning 5 of 8 comparable metrics.

JAZZ delivers a 0.7% return on equity — every $100 of shareholder capital generates $1 in annual profit, vs $-9 for AVNS. AVNS carries lower financial leverage with a 0.17x debt-to-equity ratio, signaling a more conservative balance sheet compared to JAZZ's 1.26x.

MetricJAZZ logoJAZZJazz Pharmaceutic…AVNS logoAVNSAvanos Medical, I…
ROE (TTM)Return on equity+0.7%-8.9%
ROA (TTM)Return on assets+0.3%-6.6%
ROICReturn on invested capital+2.1%-5.4%
ROCEReturn on capital employed+2.2%-6.5%
Piotroski ScoreFundamental quality 0–955
Debt / EquityFinancial leverage1.26x0.17x
Net DebtTotal debt minus cash$4.0B$39M
Cash & Equiv.Liquid assets$1.4B$90M
Total DebtShort + long-term debt$5.4B$129M
Interest CoverageEBIT ÷ Interest expense-3.72x-16.71x
JAZZ leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

JAZZ leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in JAZZ five years ago would be worth $13,224 today (with dividends reinvested), compared to $5,773 for AVNS. Over the past 12 months, JAZZ leads with a +105.6% total return vs AVNS's +92.4%. The 3-year compound annual growth rate (CAGR) favors JAZZ at 18.1% vs AVNS's 1.8% — a key indicator of consistent wealth creation.

MetricJAZZ logoJAZZJazz Pharmaceutic…AVNS logoAVNSAvanos Medical, I…
YTD ReturnYear-to-date+32.0%+121.1%
1-Year ReturnPast 12 months+105.6%+92.4%
3-Year ReturnCumulative with dividends+64.8%+5.4%
5-Year ReturnCumulative with dividends+32.2%-42.3%
10-Year ReturnCumulative with dividends+58.3%-15.7%
CAGR (3Y)Annualised 3-year return+18.1%+1.8%
JAZZ leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — JAZZ and AVNS each lead in 1 of 2 comparable metrics.

JAZZ is the less volatile stock with a 0.65 beta — it tends to amplify market swings less than AVNS's 1.54 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.

MetricJAZZ logoJAZZJazz Pharmaceutic…AVNS logoAVNSAvanos Medical, I…
Beta (5Y)Sensitivity to S&P 5000.65x1.54x
52-Week HighHighest price in past year$230.40$24.80
52-Week LowLowest price in past year$97.50$9.30
% of 52W HighCurrent price vs 52-week peak+99.2%+99.7%
RSI (14)Momentum oscillator 0–10067.790.7
Avg Volume (50D)Average daily shares traded956K1.3M
Evenly matched — JAZZ and AVNS each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates JAZZ as "Buy" and AVNS as "Hold". Consensus price targets imply -5.4% upside for JAZZ (target: $216) vs -7.0% for AVNS (target: $23).

MetricJAZZ logoJAZZJazz Pharmaceutic…AVNS logoAVNSAvanos Medical, I…
Analyst RatingConsensus buy/hold/sellBuyHold
Price TargetConsensus 12-month target$216.14$23.00
# AnalystsCovering analysts488
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap+0.9%+0.3%
Insufficient data to determine a leader in this category.
Key Takeaway

JAZZ leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.

Best OverallJazz Pharmaceuticals plc (JAZZ)Leads 4 of 6 categories
Loading custom metrics...

JAZZ vs AVNS: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is JAZZ or AVNS a better buy right now?

For growth investors, Jazz Pharmaceuticals plc (JAZZ) is the stronger pick with 4.

9% revenue growth year-over-year, versus 1. 9% for Avanos Medical, Inc. (AVNS). Analysts rate Jazz Pharmaceuticals plc (JAZZ) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — JAZZ or AVNS?

Over the past 5 years, Jazz Pharmaceuticals plc (JAZZ) delivered a total return of +32.

2%, compared to -42. 3% for Avanos Medical, Inc. (AVNS). Over 10 years, the gap is even starker: JAZZ returned +58. 3% versus AVNS's -15. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — JAZZ or AVNS?

By beta (market sensitivity over 5 years), Jazz Pharmaceuticals plc (JAZZ) is the lower-risk stock at 0.

65β versus Avanos Medical, Inc. 's 1. 54β — meaning AVNS is approximately 138% more volatile than JAZZ relative to the S&P 500. On balance sheet safety, Avanos Medical, Inc. (AVNS) carries a lower debt/equity ratio of 17% versus 126% for Jazz Pharmaceuticals plc — giving it more financial flexibility in a downturn.

04

Which is growing faster — JAZZ or AVNS?

By revenue growth (latest reported year), Jazz Pharmaceuticals plc (JAZZ) is pulling ahead at 4.

9% versus 1. 9% for Avanos Medical, Inc. (AVNS). On earnings-per-share growth, the picture is similar: Avanos Medical, Inc. grew EPS 82. 9% year-over-year, compared to -167. 5% for Jazz Pharmaceuticals plc. Over a 3-year CAGR, JAZZ leads at 5. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — JAZZ or AVNS?

Jazz Pharmaceuticals plc (JAZZ) is the more profitable company, earning -8.

3% net margin versus -9. 7% for Avanos Medical, Inc. — meaning it keeps -8. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JAZZ leads at 5. 3% versus -8. 8% for AVNS. At the gross margin level — before operating expenses — JAZZ leads at 88. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is JAZZ or AVNS more undervalued right now?

On forward earnings alone, Jazz Pharmaceuticals plc (JAZZ) trades at 9.

5x forward P/E versus 24. 7x for Avanos Medical, Inc. — 15. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for JAZZ: -5. 4% to $216. 14.

07

Which pays a better dividend — JAZZ or AVNS?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is JAZZ or AVNS better for a retirement portfolio?

For long-horizon retirement investors, Jazz Pharmaceuticals plc (JAZZ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

65)). Avanos Medical, Inc. (AVNS) carries a higher beta of 1. 54 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (JAZZ: +58. 3%, AVNS: -15. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between JAZZ and AVNS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.

Stocks Like

JAZZ

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
  • Gross Margin > 40%
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AVNS

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Gross Margin > 29%
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Beat Both

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Revenue Growth>
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(JAZZ: 19.1% · AVNS: 8.8%)

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