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Stock Comparison

KLRS vs REPL vs ADMA vs JPM vs IMVT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
KLRS
Kalaris Therapeutics Inc

Biotechnology

HealthcareNASDAQ • US
Market Cap$81M
5Y Perf.-46.1%
REPL
Replimune Group, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$733M
5Y Perf.-8.9%
ADMA
ADMA Biologics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.90B
5Y Perf.-58.6%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+30.7%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.+96.7%

KLRS vs REPL vs ADMA vs JPM vs IMVT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
KLRS logoKLRS
REPL logoREPL
ADMA logoADMA
JPM logoJPM
IMVT logoIMVT
IndustryBiotechnologyBiotechnologyBiotechnologyBanks - DiversifiedBiotechnology
Market Cap$81M$733M$1.90B$896.00B$6.90B
Revenue (TTM)$0.00$510M$280.33B$0.00
Net Income (TTM)$-44M$-315M$165M$57.05B$-506M
Gross Margin61.3%60.0%
Operating Margin42.1%25.9%
Forward P/E9.9x14.4x
Total Debt$1M$76M$80M$942.38B$72K
Cash & Equiv.$98M$111M$88M$343.34B$902M

KLRS vs REPL vs ADMA vs JPM vs IMVTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

KLRS
REPL
ADMA
JPM
IMVT
StockMar 25Jun 26Return
Kalaris Therapeutic… (KLRS)10053.9-46.1%
Replimune Group, In… (REPL)10091.1-8.9%
ADMA Biologics, Inc. (ADMA)10041.4-58.6%
JPMorgan Chase & Co. (JPM)100130.7+30.7%
Immunovant, Inc. (IMVT)100196.7+96.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: KLRS vs REPL vs ADMA vs JPM vs IMVT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ADMA leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Kalaris Therapeutics Inc is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. JPM and IMVT also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇ADMA emerged as the overall leader. Track its performance:
KLRS
Kalaris Therapeutics Inc
The Defensive Pick

KLRS is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 0.81, Low D/E 1.8%, current ratio 12.23x
  • Beta 0.81, current ratio 12.23x
  • 100.0% revenue growth vs REPL's -39.7%
  • Beta 0.81 vs IMVT's 1.66
Best for: sleep-well-at-night and defensive
REPL
Replimune Group, Inc.
The Healthcare Pick

Among these 5 stocks, REPL doesn't own a clear edge in any measured category.

Best for: healthcare exposure
ADMA
ADMA Biologics, Inc.
The Growth Play

ADMA carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 19.6%, EPS growth -25.9%, 3Y rev CAGR 49.0%
  • Better valuation composite
  • 32.4% margin vs KLRS's -1.2%
  • 27.4% ROA vs REPL's -72.2%, ROIC 36.0% vs -51.9%
Best for: growth exposure
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM ranks third and is worth considering specifically for income & stability and long-term compounding.

  • Dividend streak 15 yrs, beta 0.94, yield 1.9%
  • 465.8% 10Y total return vs IMVT's 237.9%
  • 1.9% yield; 15-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability and long-term compounding
IMVT
Immunovant, Inc.
The Momentum Pick

IMVT is the clearest fit if your priority is momentum.

  • +110.9% vs ADMA's -62.0%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthKLRS logoKLRS100.0% revenue growth vs REPL's -39.7%
ValueADMA logoADMABetter valuation composite
Quality / MarginsADMA logoADMA32.4% margin vs KLRS's -1.2%
Stability / SafetyKLRS logoKLRSBeta 0.81 vs IMVT's 1.66
DividendsJPM logoJPM1.9% yield; 15-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)IMVT logoIMVT+110.9% vs ADMA's -62.0%
Efficiency (ROA)ADMA logoADMA27.4% ROA vs REPL's -72.2%, ROIC 36.0% vs -51.9%

KLRS vs REPL vs ADMA vs JPM vs IMVT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

KLRSKalaris Therapeutics Inc

Segment breakdown not available.

REPLReplimune Group, Inc.

Segment breakdown not available.

ADMAADMA Biologics, Inc.
FY 2024
ADMA BioManufacturing Segment
97.4%$416M
Plasma Collection Centers Segment
2.6%$11M
JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000
IMVTImmunovant, Inc.

Segment breakdown not available.

KLRS vs REPL vs ADMA vs JPM vs IMVT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLADMALAGGINGIMVT

Income & Cash Flow (Last 12 Months)

ADMA leads this category, winning 3 of 5 comparable metrics.

JPM and IMVT operate at a comparable scale, with $280.3B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to JPM's 20.4%.

MetricKLRS logoKLRSKalaris Therapeut…REPL logoREPLReplimune Group, …ADMA logoADMAADMA Biologics, I…JPM logoJPMJPMorgan Chase & …IMVT logoIMVTImmunovant, Inc.
RevenueTrailing 12 months$0$510M$280.3B$0
EBITDAEarnings before interest/tax-$46M-$323M$221M$81.4B-$532M
Net IncomeAfter-tax profit-$44M-$315M$165M$57.0B-$506M
Free Cash FlowCash after capex-$49M-$283M$108M$100.9B-$407M
Gross MarginGross profit ÷ Revenue+61.3%+60.0%
Operating MarginEBIT ÷ Revenue+42.1%+25.9%
Net MarginNet income ÷ Revenue+32.4%+20.4%
FCF MarginFCF ÷ Revenue+21.2%+36.0%
Rev. Growth (YoY)Latest quarter vs prior year-0.3%
EPS Growth (YoY)Latest quarter vs prior year+81.7%+2.5%+72.7%+16.0%-14.1%
ADMA leads this category, winning 3 of 5 comparable metrics.

Valuation Metrics

Evenly matched — ADMA and JPM each lead in 2 of 6 comparable metrics.

At 13.7x trailing earnings, ADMA trades at a 14% valuation discount to JPM's 16.0x P/E. On an enterprise value basis, ADMA's 9.5x EV/EBITDA is more attractive than JPM's 18.4x.

MetricKLRS logoKLRSKalaris Therapeut…REPL logoREPLReplimune Group, …ADMA logoADMAADMA Biologics, I…JPM logoJPMJPMorgan Chase & …IMVT logoIMVTImmunovant, Inc.
Market CapShares × price$81M$733M$1.9B$896.0B$6.9B
Enterprise ValueMkt cap + debt − cash-$16M$698M$1.9B$1.50T$6.0B
Trailing P/EPrice ÷ TTM EPS-1.52x-2.89x13.68x16.00x-12.14x
Forward P/EPrice ÷ next-FY EPS est.9.92x14.40x
PEG RatioP/E ÷ EPS growth rate0.90x
EV / EBITDAEnterprise value multiple9.50x18.36x
Price / SalesMarket cap ÷ Revenue3.73x3.20x
Price / BookPrice ÷ Book value/share0.84x1.72x4.21x2.47x7.19x
Price / FCFMarket cap ÷ FCF68.40x8.88x
Evenly matched — ADMA and JPM each lead in 2 of 6 comparable metrics.

Profitability & Efficiency

ADMA leads this category, winning 6 of 9 comparable metrics.

ADMA delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $-103 for REPL. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), ADMA scores 5/9 vs IMVT's 2/9, reflecting solid financial health.

MetricKLRS logoKLRSKalaris Therapeut…REPL logoREPLReplimune Group, …ADMA logoADMAADMA Biologics, I…JPM logoJPMJPMorgan Chase & …IMVT logoIMVTImmunovant, Inc.
ROE (TTM)Return on equity-72.8%-102.7%+39.0%+15.9%-68.2%
ROA (TTM)Return on assets-43.5%-72.2%+27.4%+1.3%-62.2%
ROICReturn on invested capital-51.9%+36.0%+4.5%
ROCEReturn on capital employed-41.0%-55.9%+38.8%+8.9%-68.3%
Piotroski ScoreFundamental quality 0–932552
Debt / EquityFinancial leverage0.02x0.18x0.17x2.60x0.00x
Net DebtTotal debt minus cash-$97M-$35M-$8M$599.0B-$902M
Cash & Equiv.Liquid assets$98M$111M$88M$343.3B$902M
Total DebtShort + long-term debt$1M$76M$80M$942.4B$72,000
Interest CoverageEBIT ÷ Interest expense-31.98x-48.62x50.85x0.74x
ADMA leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JPM leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ADMA five years ago would be worth $44,620 today (with dividends reinvested), compared to $2,561 for REPL. Over the past 12 months, IMVT leads with a +110.9% total return vs ADMA's -62.0%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.6% vs REPL's -27.7% — a key indicator of consistent wealth creation.

MetricKLRS logoKLRSKalaris Therapeut…REPL logoREPLReplimune Group, …ADMA logoADMAADMA Biologics, I…JPM logoJPMJPMorgan Chase & …IMVT logoIMVTImmunovant, Inc.
YTD ReturnYear-to-date-47.8%-0.2%-54.1%-0.5%+29.8%
1-Year ReturnPast 12 months+56.9%-10.2%-62.0%+21.8%+110.9%
3-Year ReturnCumulative with dividends-52.5%-62.1%+112.1%+138.2%+55.0%
5-Year ReturnCumulative with dividends-52.5%-74.4%+346.2%+118.2%+213.0%
10-Year ReturnCumulative with dividends-52.5%-41.4%+15.3%+465.8%+237.9%
CAGR (3Y)Annualised 3-year return-22.0%-27.7%+28.5%+33.6%+15.7%
JPM leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — KLRS and JPM each lead in 1 of 2 comparable metrics.

KLRS is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than IMVT's 1.66 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. JPM currently trades 95.1% from its 52-week high vs KLRS's 36.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricKLRS logoKLRSKalaris Therapeut…REPL logoREPLReplimune Group, …ADMA logoADMAADMA Biologics, I…JPM logoJPMJPMorgan Chase & …IMVT logoIMVTImmunovant, Inc.
Beta (5Y)Sensitivity to S&P 5000.81x0.84x1.11x0.94x1.66x
52-Week HighHighest price in past year$11.88$13.24$22.20$337.25$36.27
52-Week LowLowest price in past year$2.14$1.50$7.21$262.71$14.32
% of 52W HighCurrent price vs 52-week peak+36.4%+67.1%+37.0%+95.1%+92.7%
RSI (14)Momentum oscillator 0–10039.763.444.959.157.9
Avg Volume (50D)Average daily shares traded86K8.9M5.0M7.0M1.9M
Evenly matched — KLRS and JPM each lead in 1 of 2 comparable metrics.

Analyst Outlook

JPM leads this category, winning 1 of 1 comparable metric.

Analyst consensus: REPL as "Buy", ADMA as "Buy", JPM as "Buy", IMVT as "Buy". Consensus price targets imply 331.2% upside for KLRS (target: $19) vs 5.9% for JPM (target: $340). JPM is the only dividend payer here at 1.86% yield — a key consideration for income-focused portfolios.

MetricKLRS logoKLRSKalaris Therapeut…REPL logoREPLReplimune Group, …ADMA logoADMAADMA Biologics, I…JPM logoJPMJPMorgan Chase & …IMVT logoIMVTImmunovant, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$18.67$14.00$21.00$339.75$43.67
# AnalystsCovering analysts15106123
Dividend YieldAnnual dividend ÷ price+1.9%
Dividend StreakConsecutive years of raises0115
Dividend / ShareAnnual DPS$5.95
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+1.7%+3.9%0.0%
JPM leads this category, winning 1 of 1 comparable metric.
Key Takeaway

ADMA leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). JPM leads in 2 (Total Returns, Analyst Outlook). 2 tied.

Best OverallADMA Biologics, Inc. (ADMA)Leads 2 of 6 categories
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KLRS vs REPL vs ADMA vs JPM vs IMVT: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is KLRS or REPL or ADMA or JPM or IMVT a better buy right now?

For growth investors, ADMA Biologics, Inc.

(ADMA) is the stronger pick with 19. 6% revenue growth year-over-year, versus 3. 3% for JPMorgan Chase & Co. (JPM). ADMA Biologics, Inc. (ADMA) offers the better valuation at 13. 7x trailing P/E (9. 9x forward), making it the more compelling value choice. Analysts rate Replimune Group, Inc. (REPL) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — KLRS or REPL or ADMA or JPM or IMVT?

On trailing P/E, ADMA Biologics, Inc.

(ADMA) is the cheapest at 13. 7x versus JPMorgan Chase & Co. at 16. 0x. On forward P/E, ADMA Biologics, Inc. is actually cheaper at 9. 9x.

03

Which is the better long-term investment — KLRS or REPL or ADMA or JPM or IMVT?

Over the past 5 years, ADMA Biologics, Inc.

(ADMA) delivered a total return of +346. 2%, compared to -74. 4% for Replimune Group, Inc. (REPL). Over 10 years, the gap is even starker: JPM returned +465. 8% versus KLRS's -52. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — KLRS or REPL or ADMA or JPM or IMVT?

By beta (market sensitivity over 5 years), Kalaris Therapeutics Inc (KLRS) is the lower-risk stock at 0.

81β versus Immunovant, Inc. 's 1. 66β — meaning IMVT is approximately 104% more volatile than KLRS relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

05

Which is growing faster — KLRS or REPL or ADMA or JPM or IMVT?

By revenue growth (latest reported year), ADMA Biologics, Inc.

(ADMA) is pulling ahead at 19. 6% versus 3. 3% for JPMorgan Chase & Co. (JPM). On earnings-per-share growth, the picture is similar: Kalaris Therapeutics Inc grew EPS 75. 7% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — KLRS or REPL or ADMA or JPM or IMVT?

ADMA Biologics, Inc.

(ADMA) is the more profitable company, earning 28. 8% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 37. 5% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — JPM leads at 59. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is KLRS or REPL or ADMA or JPM or IMVT more undervalued right now?

On forward earnings alone, ADMA Biologics, Inc.

(ADMA) trades at 9. 9x forward P/E versus 14. 4x for JPMorgan Chase & Co. — 4. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KLRS: 331. 2% to $18. 67.

08

Which pays a better dividend — KLRS or REPL or ADMA or JPM or IMVT?

In this comparison, JPM (1.

9% yield) pays a dividend. KLRS, REPL, ADMA, IMVT do not pay a meaningful dividend and should not be held primarily for income.

09

Is KLRS or REPL or ADMA or JPM or IMVT better for a retirement portfolio?

For long-horizon retirement investors, JPMorgan Chase & Co.

(JPM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 94), 1. 9% yield, +465. 8% 10Y return). Immunovant, Inc. (IMVT) carries a higher beta of 1. 66 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (JPM: +465. 8%, IMVT: +237. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between KLRS and REPL and ADMA and JPM and IMVT?

These companies operate in different sectors (KLRS (Healthcare) and REPL (Healthcare) and ADMA (Healthcare) and JPM (Financial Services) and IMVT (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: KLRS is a small-cap quality compounder stock; REPL is a small-cap quality compounder stock; ADMA is a small-cap high-growth stock; JPM is a large-cap deep-value stock; IMVT is a small-cap quality compounder stock. JPM pays a dividend while KLRS, REPL, ADMA, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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